Highly arthritis-susceptible DA rats express IL-1beta in articular cartilage.

abstract：:A simple technique requiring only 0.2 ml whole blood for measuring the response of lymphocytes in cultures to each of various mitogens and antigens has been elaborated. The response is quantified by comparing the number of lymphocytes with and without a stimulating agent. The increment of cell numbers is given by a ce...

journal_title：Scandinavian journal of immunology

authors： Haneberg B,Wesenberg F,Aarskog D

更新日期：1978-01-01 00:00:00

abstract：:In a prospective clinical study in New Halfa Teaching Hospital, the possible association between FcgammaRIIa-R/H131 polymorphism and anti-malarial antibody responses with clinical outcome of Plasmodium falciparum malaria among Sudanese patients was investigated. A total of 256 individuals were consecutively enrolled, ...

journal_title：Scandinavian journal of immunology

authors： Nasr A,Iriemenam NC,Troye-Blomberg M,Giha HA,Balogun HA,Osman OF,Montgomery SM,ElGhazali G,Berzins K

更新日期：2007-07-01 00:00:00

abstract：:Immunohistological techniques were used to identify activated T lymphocytes within the synovial membrane of patients with rheumatoid arthritis, using the monoclonal antibody (MoAb) RFT2, which identifies a 40-k dalton molecule preferentially expressed by T blasts or activated cells. Using this reagent together with a ...

journal_title：Scandinavian journal of immunology

authors： Poulter LW,Duke O,Panayi GS,Hobbs S,Raftery MJ,Janossy G

更新日期：1985-12-01 00:00:00

abstract：:Cells of the mononuclear phagocytic system (MPS) were described as playing a decisive role in amyloidogenesis. A relationship between the amyloid enhancing factor (AEF) and MPS cells was suggested and recently AEF activity was attributed to a serine esterase (SE) of leucocytic origin. In the present study, no correlat...

journal_title：Scandinavian journal of immunology

authors： Niewold TA,Gruys E,Kisilevsky R,Shirahama TS

更新日期：1991-07-01 00:00:00

abstract：:Dendritic cells (DCs) are specific antigen-presenting cells that play critical roles in the initiation and polarization of immune responses. DCs residing in the lungs might be detected in the bronchoalveolar lavage fluid (BALF). We analysed DC compartment in the peripheral blood and BALF of patients with allergy and i...

journal_title：Scandinavian journal of immunology

authors： Kayserova J,Zentsova-Jaresova I,Budinsky V,Rozkova D,Kopecka J,Vernerova E,Pohunek P,Skalicka V,Spisek R,Sediva A

更新日期：2012-03-01 00:00:00

abstract：:Around 20 susceptibility loci for type 1 diabetes mellitus (T1DM) have been mapped. One of these loci, IDDM10, was found on chromosome 10p11-q11. Here, we investigated whether the IDDM10 locus contributes in the susceptibility to T1DM in a Russian family dataset. One hundred and fourteen simplex Russian families, each...

journal_title：Scandinavian journal of immunology

authors： Chistiakov DA,Seryogin Y,Savost'anov KV,Zilberman LI,Titovich EV,Kuraeva TL,Dedov II,Nosikov VV

更新日期：2004-09-01 00:00:00

abstract：:To compare the receptor patterns for mitogenic and non-mitogenic substances, surface glycoproteins of human lymphocytes were labelled with the lactoperioxidase-catalysed iodination technique and with a galactose oxidase-tritiated sodium borohydride technique. Labelled cells were detergent-solubilized, and the lysates ...

journal_title：Scandinavian journal of immunology

authors： Skoog VT,Nilsson SF,Weber TH

更新日期：1980-01-01 00:00:00

abstract：:Human CD26 has dipeptidyl peptidase-4 (DPP IV) enzyme activity and binds to adenosine deaminase (ADA). CD26 is costimulatory for lymphocytes and has a circulating soluble form (sCD26). DPP IV enzyme inhibition is a new successful type 2 diabetes therapy. We examined whether the ADA binding and catalytic functions of s...

journal_title：Scandinavian journal of immunology

authors： Yu DM,Slaitini L,Gysbers V,Riekhoff AG,Kähne T,Knott HM,De Meester I,Abbott CA,McCaughan GW,Gorrell MD

更新日期：2011-02-01 00:00:00

abstract：:In mice, an in vitro cell-mediated cytotoxicity is directed towards syngeneic erythrocytes used as targets. This phenomenon occurs in lymphoid organs of normal, non-immunized mice. Its intensity is greater in the thymus than in spleen or lymph nodes. The study of the nature of the cell responsible for this spontaneous...

journal_title：Scandinavian journal of immunology

authors： Charreire J,Bach JF

更新日期：1982-07-01 00:00:00

abstract：:CD8+ T cells are thought to play an important role in protective immunity against tuberculosis. We report the identification of three peptides derived from Rv1818c, Rv3812 and Rv3018c proteins of Mycobacterium tuberculosis that bound to HLA-A*0201 molecules and their ability to induce in vitro T-cell response in perip...

journal_title：Scandinavian journal of immunology

authors： Chaitra MG,Shaila MS,Chandra NR,Nayak R

更新日期：2008-04-01 00:00:00

abstract：:The enhancement of the lytic capacity of mouse splenic 'natural killer' (NK) cells by interferon has been studied in vitro as a model for NK cell differentiation from inactive immediate precursors. We show that the increased cytotoxicity is a function of interferon concentration, and that two stages in the NK cell dif...

journal_title：Scandinavian journal of immunology

authors： Senik A,Kolb JP,Orn A,Gidlund M

更新日期：1980-01-01 00:00:00

abstract：:It was reported that the expression of Toll-like receptor (TLR) 9 may be related to Th2-type allergic inflammation including allergic rhinitis (AR). However, little is known about the expression of TLR9 in the basophils in AR. In the present study, the expression of TLR9 was examined by flow cytometry analysis, and th...

journal_title：Scandinavian journal of immunology

authors： Zhong Q,Zhan M,Wang L,Chen D,Zhao N,Wang J,Huang Y,Zhang X,He S,Zhang H

更新日期：2020-11-28 00:00:00

abstract：:Allograft rejection involves T-cell activation, requiring T-cell receptor interactions with major histocompatibility complex (MHC) molecules and costimulatory signals delivered through the B7-CD28 pathway. We evaluated the effect of blocking this pathway on graft rejection and survival, in a rat experimental model of ...

journal_title：Scandinavian journal of immunology

authors： Kurlberg G,Haglind E,Schön K,Törnqvist H,Lycke N

更新日期：2000-03-01 00:00:00

abstract：:Antibodies to interleukin-2 (IL-2) have been reported in the sera of patients under therapies involving this cytokine and in the sera of patients infected with human immunodeficiency virus (HIV). Our study proves that auto-antibodies to IL-2 are present also, at a lower titre, in healthy individuals. These antibodies ...

journal_title：Scandinavian journal of immunology

authors： Tiberio L,Caruso A,Pozzi A,Rivoltini L,Morelli D,Monti E,Balsari A

更新日期：1993-11-01 00:00:00

abstract：:Antibodies against IL-1 alpha were detected in sera of apparently healthy individuals. The immunoglobulins belonged to the IgG class, particularly IgG1, IgG2, and IgG4. [125I]rIL-1 alpha bound to Fab fragments of IgG, and IgG immune complexes of molecular weights from 160 to 700 kDa were formed in the sera by [125I]rI...

journal_title：Scandinavian journal of immunology

authors： Svenson M,Bagge Hansen M,Bendtzen K

更新日期：1990-12-01 00:00:00

abstract：:The molecular status of Abs in the vaginal fluid is reconsidered as a basis for immunization strategies for women' vaccination against HIV. Analysis of separated immunoglobulins (Igs) shows a large proportion of uncleaved IgG, whereas the low amount of IgA includes SIgA, monomers and fragments. SIgM is at a very low l...

journal_title：Scandinavian journal of immunology

authors： Hocini H,Barra A,Bélec L,Iscaki S,Preud'homme JL,Pillot J,Bouvet JP

更新日期：1995-08-01 00:00:00

abstract：:The oral commensal bacterium Streptococcus gordonii has been gathering interest as a candidate live mucosal vaccine delivery vector. S. gordonii has been shown to be capable of activating antigen presenting immune cells in a manner which leads to their activation and maturation, yet the mechanism used by S. gordonii t...

journal_title：Scandinavian journal of immunology

authors： Mayer ML,Phillips CM,Townsend RA,Halperin SA,Lee SF

更新日期：2009-04-01 00:00:00

abstract：:Mycobacteria preferentially reside in resident macrophages whereas activated macrophages are presumed to eliminate the bacteria effectively. The aim of the present study was to determine the antibacterial activities of resident and activated murine peritoneal macrophages against Mycobacterium fortuitum and the intrace...

journal_title：Scandinavian journal of immunology

authors： Nibbering PH,Yoshida SI,van den Barselaar MT,van Furth R

更新日期：1994-08-01 00:00:00

abstract：:The objective of the study was to investigate the antigen specificity and occurrence of individual autoantibodies in mothers of children diagnosed with atrioventricular (AV) block in a nation-wide setting. Patients with AV block detected before 15 years of age were identified using national quality registries as well ...

journal_title：Scandinavian journal of immunology

authors： Salomonsson S,Dzikaite V,Zeffer E,Eliasson H,Ambrosi A,Bergman G,Fernlund E,Theander E,Ohman A,Rydberg A,Skogh T,Wållberg-Jonsson S,Elfving A,Fored M,Ekbom A,Lundström U,Mellander M,Winqvist O,Sonesson SE,Gadler F,

更新日期：2011-11-01 00:00:00

abstract：:Spleen effector cells for IgG- and IgM-induced antibody-dependent cellular cytotoxicity (ADCC) were characterized with respect to density and cell surface markers by using sheep erythrocytes (SRBC) coated with hybridoma-derived monoclonal anti-SRBC IgG or anti-SRBC IgM antibodies as targets. While basically the same e...

journal_title：Scandinavian journal of immunology

authors： Zöller M,Andrighetto GC,Heyman B,Lamon EW,Wigzell H

更新日期：1983-01-01 00:00:00

abstract：:Using ELISA, we have quantified the levels of IL-2 and IFN-gamma in the oral mucosa, ear skin and regional and distant lymph nodes in an experimental murine model of contact sensitivity (CS), induced by the hapten oxazolone (OXA). Compared to normal conditions, the levels of IL-2 peaked early (4-6 h) after hapten expo...

journal_title：Scandinavian journal of immunology

authors： Ahlfors EE,Lyberg T

更新日期：2010-07-01 00:00:00

abstract：:Modulation of cytotoxic responses by viral immunoevasins plays an important role in the establishment of latent and persistent viral infections. Together with MHC class-I-restricted CD8T-lymphocytes, non-MHC-restricted natural killer (NK) and lymphokine-activated killer (LAK) cells participate in this anti-viral contr...

journal_title：Scandinavian journal of immunology

authors： Cartier A,Masucci MG

更新日期：2004-12-01 00:00:00

abstract：:In the present study evidence is presented that SAA in serum complexes to a carrier protein with a molecular weight of 100,000-200,000 daltons, with mobility in the alpha-region on electrophoresis, and with a rather low normal serum concentration. The carrier protein is apparently not albumin. SAA isolated from the ca...

journal_title：Scandinavian journal of immunology

authors： Skogen B,Natvig JB,Michaelsen TE,Anders RF

更新日期：1977-01-01 00:00:00

abstract：:Coeliac disease (CD) is becoming a model for understanding the pathogenesis of autoimmune disorders. In CD, antibodies against transglutaminase 2 (TG2) and specific residues of gliadins have been identified. A similar situation is seen in rheumatoid arthritis (RA) with both anti-citrullinated protein antibodies (ACPA)...

journal_title：Scandinavian journal of immunology

authors： Bodil Roth E,Theander E,Londos E,Sandberg-Wollheim M,Larsson A,Sjöberg K,Stenberg P

更新日期：2008-06-01 00:00:00

abstract：:A substantial proportion of immunologists, microbiologists and health professionals--and, indeed, many dictionaries--currently regard the term pathogen as a synonym for a pathogenic organism (most often a micro-organism). I will argue that this is a distortion of its original meaning--'a specific causative agent of di...

journal_title：Scandinavian journal of immunology

authors： Cunliffe J

更新日期：2008-08-01 00:00:00

abstract：:Beta-2 microglobulin (beta 2m) gene 'knock-out' mice (C1D) were primed with purified H-2Kb and H-2Db molecules and spleen cells from immunized mice were used to generate monoclonal antibody secreting B-cell hybridomas. Approximately 0.2% of the Ig-secreting primary microcultures contained H-2b binding antibodies. Thre...

journal_title：Scandinavian journal of immunology

authors： Claesson MH,Endel B,Ulrik J,Pedersen LO,Skov S,Buus S

更新日期：1994-08-01 00:00:00

abstract：:In the present study we describe the production and characterization of a panel of monoclonal antibodies (MoAbs) directed against cruzipain (Crz), the major cysteine proteinase from Trypanosoma cruzi. The five MoAbs, BD6, BF2, CG2, CH8, and DC10 were analysed with respect to affinity and specificity. None of the MoAbs...

journal_title：Scandinavian journal of immunology

authors： Gonzalez G,Orn A,Cazzulo JJ,Grönvik KO

更新日期：1994-10-01 00:00:00

abstract：:Using a recently developed murine model of haematogenously induced Staphylococcus aureus, the authors have characterized the phenotypes and functional properties of inflammatory cells present in the synovium of arthritic mice. The results show that large numbers of granulocytes and macrophages were observed in the inf...

journal_title：Scandinavian journal of immunology

authors： Abdelnour A,Bremell T,Holmdahl R,Tarkowski A

更新日期：1994-04-01 00:00:00

abstract：:After intravenous injection of 10(5) purified, lymph node (LN)-derived dm2 (H-2d/Ld-) CD4+ T cells into young C.B-17 scid/scid (severe combined immunodeficiency, SCID) mice (H-2d/Ld+), the transplanted Ld-T cells show a selective pattern of engraftment: they repopulate the spleen, the lamina propria of the small intes...

journal_title：Scandinavian journal of immunology

authors： Rudolphi A,Enssle KH,Claesson MH,Reimann J

更新日期：1993-07-01 00:00:00

abstract：:Depletion of adherent cells from stimulator and responder lymphocytes by a single filtration through nylon wool columns led to complete abrogation of the cytotoxic response to the stimulating alloantigen. Cytotoxic responses were restored by adding anti-Thy-1 + complement-greated normal peritoneal exudate cells (PEC) ...

journal_title：Scandinavian journal of immunology

authors： Symington FW,Teh HS

更新日期：1980-01-01 00:00:00