Abstract:
:In mice, an in vitro cell-mediated cytotoxicity is directed towards syngeneic erythrocytes used as targets. This phenomenon occurs in lymphoid organs of normal, non-immunized mice. Its intensity is greater in the thymus than in spleen or lymph nodes. The study of the nature of the cell responsible for this spontaneous syngeneic cytotoxicity ruled out the role of macrophages. The involvement of T cells in this phenomenon is assessed by its disappearance after the lymphoid cells had been treated with anti-theta serum plus complement, by its disappearance from lymphoid organs of mice previously treated by hydrocortisone, and by its decrease in the presence of synthetic thymic factor. Moreover, spontaneous syngeneic cytotoxicity is lost when lymphoid cells are depleted at autologous rosettes by centrifugation on a Ficoll-Hypaque gradient after rosette formation. Cytotoxic lymphocytes might belong to the population of auto-rosettes previously characterized as a population of immature T cells.
journal_name
Scand J Immunoljournal_title
Scandinavian journal of immunologyauthors
Charreire J,Bach JFdoi
10.1111/j.1365-3083.1982.tb00692.xsubject
Has Abstractpub_date
1982-07-01 00:00:00pages
1-8issue
1eissn
0300-9475issn
1365-3083journal_volume
16pub_type
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journal_title:Scandinavian journal of immunology
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journal_title:Scandinavian journal of immunology
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journal_title:Scandinavian journal of immunology
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journal_title:Scandinavian journal of immunology
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journal_title:Scandinavian journal of immunology
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journal_title:Scandinavian journal of immunology
pub_type: 杂志文章
doi:10.1046/j.1365-3083.1996.d01-70.x
更新日期:1996-05-01 00:00:00
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journal_title:Scandinavian journal of immunology
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journal_title:Scandinavian journal of immunology
pub_type: 杂志文章
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更新日期:1996-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:1993-07-01 00:00:00
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journal_title:Scandinavian journal of immunology
pub_type: 杂志文章
doi:10.1111/j.1365-3083.1979.tb03176.x
更新日期:1979-01-01 00:00:00
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journal_title:Scandinavian journal of immunology
pub_type: 杂志文章
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更新日期:1991-02-01 00:00:00
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journal_title:Scandinavian journal of immunology
pub_type: 杂志文章
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journal_title:Scandinavian journal of immunology
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pub_type: 杂志文章
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更新日期:2008-02-01 00:00:00
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journal_title:Scandinavian journal of immunology
pub_type: 杂志文章
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更新日期:1975-01-01 00:00:00
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journal_title:Scandinavian journal of immunology
pub_type: 杂志文章
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更新日期:2000-03-01 00:00:00
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更新日期:2012-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:2001-02-01 00:00:00
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journal_title:Scandinavian journal of immunology
pub_type: 杂志文章,评审
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更新日期:2021-01-01 00:00:00
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journal_title:Scandinavian journal of immunology
pub_type: 杂志文章
doi:10.1111/j.1365-3083.1976.tb00306.x
更新日期:1976-01-01 00:00:00
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journal_title:Scandinavian journal of immunology
pub_type: 杂志文章
doi:10.1111/j.1365-3083.1984.tb01032.x
更新日期:1984-12-01 00:00:00