Expression of G protein αq Subunit is Decreased in Lymphocytes from Patients with Rheumatoid Arthritis and is Correlated with Disease Activity.

abstract：:Infection with murine gammaherpesvirus 68 has become an accepted model for studying the virus/host interactions with regard to gammaherpesvirus infections. Previous studies using gene-deficient mice have revealed that neither IFNγ nor perforin is essential in controlling the outcome of infection or the virus load duri...

journal_title：Scandinavian journal of immunology

authors： Bartholdy C,Høgh-Petersen M,Storm P,Holst PJ,Orskov C,Christensen JP,Thomsen AR

更新日期：2014-06-01 00:00:00

abstract：:Antibodies to crude leukocyte interferon (CIF) were bound to Sepharose 4B, and CIF was chromatographed. A relationship between recovered interferon and percentage binding of the antibodies to Sepharose 4B was observed. Highest recovery was obtained when only 50%-85% of th- antibodies were bound. When CIF was subjected...

journal_title：Scandinavian journal of immunology

authors： Berg K

更新日期：1977-01-01 00:00:00

abstract：:Using rocket immunoelectrophoresis and indirect haemagglutination tests, antibodies to nicotinic acetylcholine receptor (n-AChR) from Torpedo marmorata were detected in sera from rabbits with experimental myasthenia but not in sera from patients with myasthenia gravis or in rabbit antisera to a partly purified skeleta...

journal_title：Scandinavian journal of immunology

authors： Aarli JA,Mattsson C,Heilbronn E

更新日期：1975-01-01 00:00:00

abstract：:Inflammatory bowel diseases (IBD) are a group of chronic recurrent gastrointestinal inflammatory diseases, including ulcerative colitis (UC), Crohn's disease (CD) and IBD unclassified. The pathogenesis may be related to the mucosal immune dysfunction in genetically susceptible hosts affected by environmental factors. ...

journal_title：Scandinavian journal of immunology

authors： Zhang X,Wang S,Ding X,Guo J,Tian Z

更新日期：2020-09-01 00:00:00

abstract：:Heterogeneity in antigen recognition of an alloreactive helper T-cell line was studied by repeated limiting dilution cloning. Analysis of the fine specificities of these clones showed that the gain of reactivity to new antigens by the T-cell line included the generation of non-cross-reactive T cells specific to new ma...

journal_title：Scandinavian journal of immunology

authors： Rajasekar R,Andersson J,Leanderson T

更新日期：1988-06-01 00:00:00

abstract：:γδ T cells are characterized by recognizing conserved endogenous and stress-induced antigens without antigen presentation. It has been show that γδ T cells play an important role in anti-tumour/microbe responses, but their function in autoimmune diseases is yet not clear. Here, we reported the quantity and phenotype o...

journal_title：Scandinavian journal of immunology

authors： Wang L,Kang N,Zhou J,Guo Y,Zhang X,Cui L,Ba D,He W

更新日期：2012-07-01 00:00:00

abstract：:The lectin pathway (LP) of the complement system may initiate inflammatory reactions when body tissue is altered. We aimed to investigate levels of the LP proteins in out-of-hospital cardiac arrest patients, and to compare these with healthy individuals. Furthermore, we aimed to clarify whether duration of targeted te...

journal_title：Scandinavian journal of immunology

authors： Haugaard SF,Jeppesen AN,Troldborg A,Kirkegaard H,Thiel S,Hvas AM

更新日期：2018-06-09 00:00:00

abstract：:During B-cell development in the avian bursa of Fabricius most of the developing B cells die by apoptosis and only a minority survive to emigrate into the periphery. Recently, it has been shown that when developing bursal cells become mature and ready to migrate they start to express chL12 antigen. The expression of t...

journal_title：Scandinavian journal of immunology

authors： Lampisuo M,Arstila TP,Liippo J,Lassila O

更新日期：1998-03-01 00:00:00

abstract：:Peripheral blood mononuclear cells (PBM) from four patients with IgG myeloma and four patients with benign monoclonal gammopathy (BMG) were stimulated with pokeweed mitogen (PWM), and the in vitro immunoglobulin production over 7 days was measured with an enzyme-linked immunosorbent assay. All myeloma patients were su...

journal_title：Scandinavian journal of immunology

authors： Peest D,Brunkhorst U,Schedel I,Deicher H

更新日期：1984-02-01 00:00:00

abstract：:Antigen uptake and the following maturation of dendritic cells (DCs) are pivotal to the initiation of specific antimicrobial immune responses. DCs also play an important role in the recruitment and activation of the cells of the innate immune system. We have examined the interactions of DCs with Borrelia burgdorferi t...

journal_title：Scandinavian journal of immunology

authors： Suhonen J,Komi J,Soukka J,Lassila O,Viljanen MK

更新日期：2003-07-01 00:00:00

abstract：:Histoplasma capsulatum is a fungus found intracellularly in neutrophils and peripheral blood mononuclear cells (PBMCs), suggesting that it is capable of evading damage and survives inside these cells. In this study, we report that neutrophils from H. capsulatum-infected mice, and human neutrophils and mononuclear cell...

journal_title：Scandinavian journal of immunology

authors： Medeiros AI,Bonato VL,Malheiro A,Dias AR,Silva CL,Faccioli LH

更新日期：2002-10-01 00:00:00

abstract：:Autologous and allogeneic mixed lymphocyte cultures (AMC and MLC) were assayed for blastogenesis, generation of cytotoxic potential, and the effect of interferon (IFN-alpha) on these features. The cells of the mixed cultures lysed K562, Daudi, and autologous and allogeneic phytohaemagglutinin blasts. Stimulator-specif...

journal_title：Scandinavian journal of immunology

authors： Argov S,Klein E

更新日期：1983-03-01 00:00:00

abstract：:Increasing evidence suggests a key role for the innate immune system in asthma development. Although the role of Natural Killer (NK) cells in allergic asthma is poorly known, modifications of the blood NK cell populations have been found in asthmatic and/or allergic patients. Their repartition and activation status in...

journal_title：Scandinavian journal of immunology

authors： Ple C,Barrier M,Amniai L,Marquillies P,Bertout J,Tsicopoulos A,Walzer T,Lassalle P,Duez C

更新日期：2010-08-01 00:00:00

abstract：:The specificity of the Fcgamma receptors in normal spleen and liver and in malignant tissues was studied using hemadsorption to cryostat sections. Indicator cells (EA) were sheep erythrocytes (E) sensitized with rabbit IgG antibody (A). The binding of EA to sections of normal and malignant tissues was inhibited by poo...

journal_title：Scandinavian journal of immunology

authors： Matre R

更新日期：1976-01-01 00:00:00

abstract：:Human blood lymphocytes were tested for their proliferative response to purified protein derivative (PPD) in vitro. Purified T cells showed a lower response than the orginial purified lymphocyte suspension. Purified B cells were unresponsive to PPD. Mixtures of preparations of T and B cells were stimulated to a greate...

journal_title：Scandinavian journal of immunology

authors： Blomgren H

更新日期：1975-09-01 00:00:00

abstract：:We have investigated the production of interleukin 2 (IL-2) by human T cells after their stimulation by phytohaemagglutinin (PHA). T cells isolated by rosetting with sheep erythrocytes produced high levels of IL-2. Further separation of rosette-forming cells, according to the expression of Fc receptors for IgG, showed...

journal_title：Scandinavian journal of immunology

authors： Silva AG,Alvarez JM,Bonnard GD,de Landazuri MO

更新日期：1981-09-01 00:00:00

abstract：:During immunological rejection of the transplanted heart, cytotoxic T lymphocytes (CTL) infiltrate the myocardium and by damaging the myocytes contribute to loss of function. To address one important aspect of heart transplant rejection, we investigated in guinea pig ventricular myocytes how CTL-derived lytic granules...

journal_title：Scandinavian journal of immunology

authors： Binah O,Kline R,Berke G,Hoffman B

更新日期：1993-01-01 00:00:00

abstract：:The mechanisms by which glucocorticoids suppress immune responses have not yet been clearly defined. In steroid-sensitive pathological conditions, an increase in gamma delta T cells can occur in certain untreated systemic autoimmune disorders and seems to be a peristent feature in most cases of systemic lupus erythema...

journal_title：Scandinavian journal of immunology

authors： Spinozzi F,Agea E,Bistoni O,Travetti A,Migliorati G,Moraca R,Nicoletti I,Riccardi C,Paoletti FP,Vaccaro R

更新日期：1995-05-01 00:00:00

abstract：:The monoclonal antibodies A and B specific for the HN molecule of Sendai virus were used to induce polyclonal and monoclonal anti-idiotypic antibodies. No response was observed in allogeneic Lewis rats, low responses in syngeneic LOU rats, and high responses in allogeneic BN rats and xenogeneic Balb/c mice. The monocl...

journal_title：Scandinavian journal of immunology

authors： Fenner M,Siegmann K,Binz H

更新日期：1986-09-01 00:00:00

abstract：:Interleukin-12 receptor deficiency is a well-described cause of human susceptibility to infection with low-virulent mycobacteria and Salmonella species. We identified a male patient presenting in his late forties with severe gastroenteropathy because of outbred infestation by a previously unknown mycobacterium. In add...

journal_title：Scandinavian journal of immunology

authors： Schejbel L,Rasmussen EM,Kemp HB,Lundstedt AC,Nielsen KR,Obel N,Marquart H,Andersen AB

更新日期：2011-12-01 00:00:00

abstract：:The occurrence of D-D recombination during the embryonic differentiation of chicken B cells was studied. Ig heavy (H) chains were amplified by polymerase chain reaction from day-12 bursal cDNA, and 30 random V-D-J regions were analysed by DNA sequencing. No gene conversion events were observed in any of the V regions,...

journal_title：Scandinavian journal of immunology

authors： Mansikka A,Toivanen P

更新日期：1991-05-01 00:00:00

abstract：:Six synthetic peptides of the MHC class I molecule corresponding to individual H-2Kb participants in amino acid sequences of domains alpha 1 (peptide 1 and 2) and alpha 2 (peptides 3, 4, 5, 6) were selected. Kb-specific suppressor T cells (Ts) were induced in vivo in mice, then pretreated with a set of peptides and as...

journal_title：Scandinavian journal of immunology

authors： Brondz BD,Anfalova TV,Pavlova LS,Pankratova EV,Kojich AG,Moshnikov SA

更新日期：1993-06-01 00:00:00

abstract：:Prolonged antigenic stimulation results in lymphocyte shedding of CD27, a member of the tumour necrosis factor receptor (TNFR) family, and transformation to a stable phenotype capable of synthesizing interleukin-4 (IL-4). Co-expression of alpha4beta7 identifies those cells with gut-homing potential. We have investigat...

journal_title：Scandinavian journal of immunology

authors： Meenan J,Spaans J,Grool TA,Lammers K,Pals S,Tytgat GN,van Deventer SJ

更新日期：1998-09-01 00:00:00

abstract：:We have investigated the ability of different cells from non-immunized mice of the BALB/c strain to present antigen to two ovalbumin-specific I-Ad-restricted T hybridomas. Lipopolysaccharide-activated B-cell blasts were found to be the most efficient antigen-presenting cells. Purified small and dense splenic B cells a...

journal_title：Scandinavian journal of immunology

authors： Gontijo CM,Möller G

更新日期：1991-08-01 00:00:00

abstract：:The addition of a small proportion (10%) of in vivo concanavalin-A (Con-A)-activated spleen cells to normal spleen cell cultures suppressed the primary immune response to sheep erythrocytes (SRBC) but had no effect on the thymus-independent primary immune response to 3,5-dinitro-4-hydroxy-phenacetyl-conjugated lipopol...

journal_title：Scandinavian journal of immunology

authors： Ekstedt RD,Waterfield JD,Nespoli L,Möller G

更新日期：1977-01-01 00:00:00

abstract：:Immune complexes were isolated by ultracentrifugation in sucrose gradients (20-65% (w/w]. the centrifugation procedure was demonstrated to be isopycnic. The banding density of the complexes was influenced by the chemical nature and molecular size of the antigen and by the antigen to antibody ratio. The method was appl...

journal_title：Scandinavian journal of immunology

authors： Rødahl E,Iversen OJ,Dalen AB

更新日期：1984-07-01 00:00:00

abstract：:The binding of a 34-kDa (mol. wt.) acylpoly(1,3)galactoside (APG) extracted from a membrane proteoglycan of Klebsiella pneumoniae to human blood leucocytes was investigated. APG is made of a long poly(1,3)galactose chain, a core-like region and a lipid moiety which comprises two glucosamine residues bound to a phospha...

journal_title：Scandinavian journal of immunology

authors： Hmama Z,Kouassi E,Panaye G,Delassan S,Normier G,Binz H,Revillard JP

更新日期：1992-07-01 00:00:00

abstract：:Beta-2 microglobulin (beta 2m) gene 'knock-out' mice (C1D) were primed with purified H-2Kb and H-2Db molecules and spleen cells from immunized mice were used to generate monoclonal antibody secreting B-cell hybridomas. Approximately 0.2% of the Ig-secreting primary microcultures contained H-2b binding antibodies. Thre...

journal_title：Scandinavian journal of immunology

authors： Claesson MH,Endel B,Ulrik J,Pedersen LO,Skov S,Buus S

更新日期：1994-08-01 00:00:00

abstract：:Plasma and serum samples from a patient with homozygous C2 deficiency and severe systemic lupus erythematosus who responded with full clinical remission after plasma infusions were examined for immune complexes (IC), C3 activation products, and the terminal complement complex (TCC). Plasma contained large amounts of C...

journal_title：Scandinavian journal of immunology

authors： Garred P,Mollnes TE,Thorsteinsson L,Erlendsson K,Steinsson K

更新日期：1990-01-01 00:00:00

abstract：:Chromosomally marked cells from the 7-day intraembryonic mesenchyme were transplanted into 14-day-old irradiated chick embryos. At the age of 6 weeks donor-derived T and B lymphocytes were shown to be present in the thymus, spleen and bone marrow, indicating that cells in the 7-day intraembryonic mesenchyme are capabl...

journal_title：Scandinavian journal of immunology

authors： Lassila O,Eskola J,Toivanen P,Dieterlen-Lièvre F

更新日期：1980-01-01 00:00:00