Lymphoid stem cells in the intraembryonic mesenchyme of the chicken.

abstract：:A search for an antigen-driven expansion of T lymphocytes in the inflamed joints in rheumatoid arthritis (RA) patients have been going on for decades. We here analyzed the human germinal centre T-cell receptor (TCR) Vbeta gene usage with polymerase chain reaction (PCR) combined with sequence analysis, to address the q...

journal_title：Scandinavian journal of immunology

authors： Källberg E,Leanderson T,Natvig JB

更新日期：2001-09-01 00:00:00

abstract：:Contagious bovine pleuropneumonia, caused by Mycoplasma mycoides ssp. mycoides biotype small colony (MmmSC), is one of the most serious cattle diseases in Africa. Several observations suggested that MmmSC had evolved an efficient way to escape the bovine immune responses by triggering host-cell cytotoxicity. This stud...

journal_title：Scandinavian journal of immunology

authors： Dedieu L,Chapey E,Balcer-Rodrigues V

更新日期：2005-12-01 00:00:00

abstract：:An antiserum to unstimulated rat peritoneal macrophages was produced in rabbits. The antibodies were directed against an acidic protein with a molecular weight of 35,000 and with an isoelectric point at 4.6. The macrophage acidic protein (MAP) was purified by gel filtration of rat lung soluble proteins, followed by pr...

journal_title：Scandinavian journal of immunology

authors： Persson LI,Hansson E,Rönnbäck L

更新日期：1981-10-01 00:00:00

abstract：:Interactions between homing receptors on circulating leucocytes and endothelial addressins regulate tissue-specific cellular extravasation. Although integrin alpha 4 beta 7 appears to be the main receptor for gut-homing T lymphocytes, less is known about molecules mediating mucosal B cell homing. Expression of integri...

journal_title：Scandinavian journal of immunology

authors： Farstad IN,Halstensen TS,Lazarovits AI,Norstein J,Fausa O,Brandtzaeg P

更新日期：1995-12-01 00:00:00

abstract：:Two monoclonal antibodies (MoAbs), F10.2 and F10.3, were selected for their ability to interfere in homotypic adhesion of human B cells. Precipitation studies and binding to intercellular adhesion molecule 1 (ICAM-1, CD54) cDNA transfected COS cells revealed that both MoAbs are directed against ICAM-1. The binding of ...

journal_title：Scandinavian journal of immunology

authors： Bloemen P,Moldenhauer G,van Dijk M,Schuurman HJ,Bloem AC

更新日期：1992-05-01 00:00:00

abstract：:Tumour regression induced in cancer patients by local instillation of Bacillus Calmette-Guérin (BCG) into the bladder has been considered to be mainly mediated by activated cellular immunity and inflammatory reactions. In the present study we investigated the cytotoxicity of T cells bearing gamma/delta T-cell receptor...

journal_title：Scandinavian journal of immunology

authors： Wang MH,Chen YQ,Gercken J,Ernst M,Böhle A,Flad HD,Ulmer AJ

更新日期：1993-09-01 00:00:00

abstract：:Changes in the concentration and composition of serum immunoglobulin A (IgA) and deposits of IgA in tissues are well-known characteristics of alcoholic liver disease. We investigated whether these changes also accompany IgA synthesis by peripheral blood mononuclear cells (MNC), by counting immunoglobulin-producing cel...

journal_title：Scandinavian journal of immunology

authors： Van de Wiel A,Seifert WF,Van der Linden JA,Gmelig-Meyling FH,Kater L,Schuurman HJ

更新日期：1987-02-01 00:00:00

abstract：:The secretion of interleukin (IL)-1 beta, IL-6 and tumour necrosis factor (TNF)-alpha were compared when freshly isolated autologous monocytes or monocytederived macrophages (MDMs) were co-cultured in vitro with autologous fragment (F)-spheroids established from a series of head and neck squamous cell carcinoma (HNSCC...

journal_title：Scandinavian journal of immunology

authors： Heimdal JH,Aarstad HJ,Olsnes C,Olofsson J

更新日期：2001-02-01 00:00:00

abstract：:The immune system defends the host against pathogenic attacks by micro-organisms and their products. It does not react against self-components due to the relatively efficient negative selection of developing T lymphocytes in the thymus. This process does permit T cells with low avidity against self to be present in th...

journal_title：Scandinavian journal of immunology

authors： Rubin B

更新日期：2009-03-01 00:00:00

abstract：:Rabbit Ig against human beta2-microglobulin was found to be mitogenic for human peripheral lymphocytes, tonsil lymphocytes, and appendix and spleen cells. Anti-beta2-m gave increased DNA synthesis, with peak responses on day 3 or 4 and showed a dose-response effect when diluted. The effect was seen in both serum-free ...

journal_title：Scandinavian journal of immunology

authors： Ringeén O,Möller E

更新日期：1975-01-01 00:00:00

abstract：:We investigated dietary antigen-specific T-cell responses in mesenteric lymph nodes (MLN) and Peyer's patches (PP) in noncolitic control mice as well as in colitis-prone mice prior to onset of histological active colitis. T cells were restimulated in vitro with constituents isolated from the mouse diet. Interestingly,...

journal_title：Scandinavian journal of immunology

authors： Bjursten M,Hultgren Hörnquist E

更新日期：2005-01-01 00:00:00

abstract：:Natural killer (NK) cell responsiveness in the mouse is determined in an education process guided by inhibitory Ly49 and NKG2A receptors binding to MHC class I molecules. It has been proposed that inhibitory signalling in human NK cells involves Abl-1 (c-Abl)-mediated phosphorylation of Crk, lowering NK cell function ...

journal_title：Scandinavian journal of immunology

authors： Ganesan S,Luu TT,Chambers BJ,Meinke S,Brodin P,Vivier E,Wetzel DM,Koleske AJ,Kadri N,Höglund P

更新日期：2017-09-01 00:00:00

abstract：:Infection with murine gammaherpesvirus 68 has become an accepted model for studying the virus/host interactions with regard to gammaherpesvirus infections. Previous studies using gene-deficient mice have revealed that neither IFNγ nor perforin is essential in controlling the outcome of infection or the virus load duri...

journal_title：Scandinavian journal of immunology

authors： Bartholdy C,Høgh-Petersen M,Storm P,Holst PJ,Orskov C,Christensen JP,Thomsen AR

更新日期：2014-06-01 00:00:00

abstract：:Autoimmune regulator's (AIRE) best characterized role is in the generation immunological tolerance, but it is also involved in many other processes such as spermatogenesis. Loss-of-function mutations in AIRE cause a disease called autoimmune polyendocrinopathy, candidiasis and ectodermal dystrophy (APECED; also called...

journal_title：Scandinavian journal of immunology

authors： Kekäläinen E,Pöntynen N,Meri S,Arstila TP,Jarva H

更新日期：2015-05-01 00:00:00

abstract：:Proteins immobilized on insoluble carriers or immunoadsorbents are now widely used in many areas of biological research. They are especially efficient in studies of complex protein mixtures because immunoadsorbents are very useful for isolation of individual components for further investigation. Antibodies immobilized...

journal_title：Scandinavian journal of immunology

authors： Nezlin R

更新日期：2005-07-01 00:00:00

abstract：:One successful approach to generate dendritic cells (DC) is to cultivate peripheral blood monocytes in fetal calf serum (FCS)-containing medium in the presence of granulocyte-macrophage colony stimulating factor (GM-CSF) and interleukin (IL)-4. Because the use of xenogenic proteins has to be strictly avoided for clini...

journal_title：Scandinavian journal of immunology

authors： Pietschmann P,Stöckl J,Draxler S,Majdic O,Knapp W

更新日期：2000-04-01 00:00:00

abstract：:Midtrimester amniotic fluid cytokines may reflect the function of the maternal immune system in the maternal-fetal interface and thus be predictive of pre-eclampsia. We determined the concentrations of interleukin (IL)-6, IL-8, IL-10, IL-11, IL-12, IL-15, tumour necrosis factor (TNF)-alpha and transforming growth fact...

journal_title：Scandinavian journal of immunology

authors： Heikkinen J,Möttönen M,Pulkki K,Lassila O,Alanen A

更新日期：2001-03-01 00:00:00

abstract：:The thymus is the major primary immune tissue for the production of functional T lymphocytes in vertebrates. However, its evolutionary origin is unknown. It has recently been shown that the generation of local T cells also occurs in gut-associated lymphoid tissues (GALT). This suggests that the thymus and GALT have si...

journal_title：Scandinavian journal of immunology

authors： Matsunaga T,Rahman A

更新日期：2001-01-01 00:00:00

abstract：:C-reactive protein (CRP) binds to Fcγ-receptors, FcγRIIa (CD32) with high affinity and to FcγRIa (CD64) with low affinity. The binding to CD32 has been shown to be allele specific, that is, it binds to R/R131 but not to H/H131. Little is known about the cooperation of CRP and neutrophilic granulocytes (PMNs) in inflam...

journal_title：Scandinavian journal of immunology

authors： Aas V,Sand KL,Asheim HC,Benestad HB,Iversen JG

更新日期：2013-06-01 00:00:00

abstract：:Mycobacteria preferentially reside in resident macrophages whereas activated macrophages are presumed to eliminate the bacteria effectively. The aim of the present study was to determine the antibacterial activities of resident and activated murine peritoneal macrophages against Mycobacterium fortuitum and the intrace...

journal_title：Scandinavian journal of immunology

authors： Nibbering PH,Yoshida SI,van den Barselaar MT,van Furth R

更新日期：1994-08-01 00:00:00

abstract：:The migration inhibition in vitro induced by measles virus material on leukocytes from 17 patients with multiple sclerosis (MS) was compared with that of 8 patients with various other central nervous system diseases and that of 12 healthy blood donors. Significant differences could not be demonstrated. The results do ...

journal_title：Scandinavian journal of immunology

authors： Nordal HJ,Froland SS,Vandvik B,Norrby E

更新日期：1976-01-01 00:00:00

abstract：:The currently used vaccine against tuberculosis, Bacille Calmette-Guérin (BCG), has variable efficacy, so new vaccine development is crucial. In this study, we evaluated a recombinant vaccine prepared from non-pathogenic Mycobacterium smegmatis (rMS) that expresses a fusion of early secreted antigenic target 6-kDa ant...

journal_title：Scandinavian journal of immunology

authors： Zhang H,Peng P,Miao S,Zhao Y,Mao F,Wang L,Bai Y,Xu Z,Wei S,Shi C

更新日期：2010-10-01 00:00:00

abstract：:Osteoclasts are responsible for bone destruction in rheumatoid arthritis (RA), and adipose-derived mesenchymal stromal cells (ADSCs) can inhibit experimental collagen-induced arthritis model. This study aims to determine whether ADSCs also suppresses osteoclastogenesis and bone erosion in collagen-induced arthritis (C...

journal_title：Scandinavian journal of immunology

authors： Chang Q,Li C,Lu Y,Geng R,Wei JN,Hu JZ

更新日期：2020-08-01 00:00:00

abstract：:Intravenous immunoglobulin (IVIG) preparations have been shown to suppress lymphocyte proliferation in vitro. This study aimed to investigate the effects of an IVIG produced by fractionation/DEAE-Sephadex adsorption on lymphocyte proliferation in vitro, with particular reference to contributions of the stabilizing age...

journal_title：Scandinavian journal of immunology

authors： Alder LB,Morgan LA,Spickett GP

更新日期：1996-12-01 00:00:00

abstract：:In murine schistosomiasis mansoni the worm egg-induced granulomatous inflammation is bi-phasic: an initial Th1 type is subsequently switched to a Th2 type response. Analysis of the cellular, molecular base of the Th1-associated response (5-6 weeks post infection) revealed mRNA messages for interleukin (IL)-12 p40, IL-...

journal_title：Scandinavian journal of immunology

authors： Todt JC,Whitfield JR,Ivard SR,Boros DL

更新日期：2000-10-01 00:00:00

abstract：:We describe a new quantitative fluorimetric assay for phagocytosis of bacteria. A suspension of fluorescein-labelled bacteria (Micrococcus lysodeikticus) is mixed and incubated with phagocytes. After fixation with paraformaldehyde, the excess non-phagocytosed and adsorbed bacteria are lysed with a solution of lysozyme...

journal_title：Scandinavian journal of immunology

authors： Vray B,Hoebeke J,Saint-Guillain M,Leloup R,Strosberg AD

更新日期：1980-01-01 00:00:00

abstract：:The effect of low-dose methotrexate (MTX) treatment on the CD26 density on circulating monocytes and CD4(+) T lymphocytes or levels of soluble CD26 (sCD26) has not yet been described in rheumatoid arthritis (RA). While CD26 in T lymphocytes is involved in the activation and proliferation of T lymphocytes, little is kn...

journal_title：Scandinavian journal of immunology

authors： Ellingsen T,Hornung N,Møller BK,Hjelm-Poulsen J,Stengaard-Pedersen K

更新日期：2007-10-01 00:00:00

abstract：:Foot-and-mouth disease (FMD) caused by FMD virus (FMDV) is a major health and economic problem in the farming industry. Vaccination of livestock against this highly infectious viral disease is crucial, and inactivated FMD vaccine has been effective at controlling infection. However, accumulated data show that the inac...

journal_title：Scandinavian journal of immunology

authors： Kang J,Zuo Y,Guo Q,Wang H,Liu Q,Liu Q,Xia G,Kang Y

更新日期：2015-11-01 00:00:00

abstract：:G-protein-coupled receptors play a major role in the activation of the innate immune system, such as polymorphonuclear neutrophils. Members of the formyl peptide receptor family recognize chemotactic peptides as well the amyloïd-beta peptide and fragments of the human immunodeficiency virus envelope and may thus be im...

journal_title：Scandinavian journal of immunology

authors： Boxio R,Bossenmeyer-Pourié C,Vanderesse R,Dournon C,Nüsse O

更新日期：2005-08-01 00:00:00

abstract：:Paratuberculosis (Johne's disease) is a chronic enteritis syndrome of ruminants, which is due to infection by Mycobacterium paratuberculosis. Cutaneous testing with proteins extracted from a mycobacterial culture fluid (johnin-PPD) is currently used to evaluate the cellular immune status. We have compared the componen...

journal_title：Scandinavian journal of immunology

authors： Gilot P,De Kesel M,Coene M,Cocito C

更新日期：1992-12-01 00:00:00