The Abl-1 Kinase is Dispensable for NK Cell Inhibitory Signalling and is not Involved in Murine NK Cell Education.

abstract：:Galectin-3 has been suggested as a pro-inflammatory mediator in animal arthritis and rheumatoid arthritis (RA). We aimed to study the serum level of galectin-3 in patients with newly diagnosed RA and associations with disease profile, Magnetic resonance imaging (MRI) findings and seromarkers of synovial matrix inflamm...

journal_title：Scandinavian journal of immunology

authors： Issa SF,Christensen AF,Lindegaard HM,Hetland ML,Hørslev-Petersen K,Stengaard-Pedersen K,Ejbjerg BJ,Lottenburger T,Ellingsen T,Pedersen JK,Junker K,Svendsen A,Tarp U,Østergaard M,Junker P

更新日期：2017-12-01 00:00:00

abstract：:Cells produced in murine T-cell colonies grown in methylcellulose have been studied to evaluate their proliferation, phenotypic differentiation, and ability to give rise to cytotoxic cells. Colony-forming cells from presumably cortical or medullary thymocytes, separated by peanut agglutination, or from lymph nodes, sh...

journal_title：Scandinavian journal of immunology

authors： Röpke C,Claësson MH

更新日期：1986-02-01 00:00:00

abstract：:The light (L) and heavy (H) chain and the idiotypic (Id) composition of the antibody (Ab) plaque-forming cells (PFC) and serum Ab specific for alpha-1,3 dextran have been characterized in murine strains exhibiting the CH-Ig-lb to e allotypes and in their F1 hybrids with Ig-la1, BALB/c prototypes. The Ab response of th...

journal_title：Scandinavian journal of immunology

authors： Bell C

更新日期：1979-03-01 00:00:00

abstract：:Cellular immune response and delayed-type hypersensitivity reactions are considered to play a major role in the immunopathogenesis of pulmonary tuberculosis (PTB). But the exact mechanism is still to be clarified. Th1 cells are mainly involved in cellular immune responses in PTB and provide a normal healing process wi...

journal_title：Scandinavian journal of immunology

authors： Aktas E,Ciftci F,Bilgic S,Sezer O,Bozkanat E,Deniz O,Citici U,Deniz G

更新日期：2009-09-01 00:00:00

abstract：:Schizophrenia is one of the most debilitating diseases among psychiatric disorders. Recent studies suggest the existence of effective immunological changes in the pathophysiology of this disease. The purpose of the current study was to determine the changes in serum levels of Brain Derived Neurotrophic Factor (BDNF) a...

journal_title：Scandinavian journal of immunology

authors： Ajami A,Hosseini SH,Taghipour M,Khalilian A

更新日期：2014-07-01 00:00:00

abstract：:The induction of T-cell apoptosis is regulated in part by monocytes (CD14+ cells). Human peripheral blood monocytes inhibited the spontaneous cell death of activated T cells in vitro. The inhibition of T-cell apoptosis did not require autologous monocytes. Inhibition required direct contact with monocytes and was not ...

journal_title：Scandinavian journal of immunology

authors： Sakata K,Sakata A,Kong L,Vela-Roch N,Talal N,Dang H

更新日期：1999-11-01 00:00:00

abstract：:We studied the inhibitory effect of a fraction of bovine seminal plasma on in vitro lymphocyte responses to specific and nonspecific ligands. Seminal plasma was fractionated by Sephadex G-100 chromatography, and the inhibitory component was found to have a molecular weight of above 100,000 daltons. This fraction was d...

journal_title：Scandinavian journal of immunology

authors： Prakash C,Coutinho A,Möller G

更新日期：1976-01-01 00:00:00

abstract：:Serum and salivary concentrations of immunoglobulin A1 (IgA1) and IgA2 were studied in 105 Icelandic children aged 0-12 years. Serum concentrations of both IgA1 and IgA2 increased slightly (P < 0.001) during childhood. The salivary IgA1/IgA2 ratio tended to decrease during the same period; this trend is less apparent ...

journal_title：Scandinavian journal of immunology

authors： Weemaes C,Klasen I,Göertz J,Beldhuis-Valkis M,Olafsson O,Haraldsson A

更新日期：2003-12-01 00:00:00

abstract：:The aim of this study was to test the hypothesis that exercise would induce inflammatory response characterized by increased pro-inflammatory cytokines - interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α), adhesion molecule, matrix metalloprotease-9 (MMP-9) and myeloperoxidase (MPO) levels. Additional aim was t...

journal_title：Scandinavian journal of immunology

authors： Reihmane D,Jurka A,Tretjakovs P

更新日期：2012-08-01 00:00:00

abstract：:To investigate the influence of genetic and/or environmental factors in the development and shaping of the human peripheral T cell repertoire the authors studied the T-cell receptor (TCR) V beta usage in 10 adult monozygous (Mz) and nine dizygous (Dz) twin pairs living in a Plasmodium falciparum endemic area in West A...

journal_title：Scandinavian journal of immunology

authors： Troye-Blomberg M,Fogdell A,el-Ghazali G,Larsson A,King MH,Sisay-Joof F,Olerup O,Grunewald J,Jepson A

更新日期：1997-05-01 00:00:00

abstract：:Physical association was measured between MLV gp70, the envelope glycoprotein of Rauscher murine leukaemia virus (R-MLV), and serologically defined H-2 antigens on the surface of R-MLV transformed C57BL/6 (H-2DbKb) mouse leukaemia cells (RBL-5A). Capping and patching with antisera against H-2Db caused specific co-capp...

journal_title：Scandinavian journal of immunology

authors： Zarling DA,Keshet I,Watson A,Bach FH

更新日期：1978-01-01 00:00:00

abstract：:Saliva was collected from 57 infants aged 6 weeks to 2.5 years and the molecular form of IgA was studied by centrifugation on sucrose density gradients. Two distinct populations were identified. Seventy-two per cent of the children had secretory IgA in their salivary secretions, while 28% had a molecular form correspo...

journal_title：Scandinavian journal of immunology

authors： Cripps AW,Gleeson M,Clancy RL

更新日期：1989-03-01 00:00:00

abstract：:The pair of microH-chain and kappa L-chain transgenes encoding the Sp6 TNP/DNA-specific IgM was bred onto the rearrangement-deficient genetic background of RAG-2T mice, and onto the kappa L-chain expression-deficient background of iE kappa T mice. Bone marrow of Sp6 transgenic RAG-2T mice contained normal numbers of B...

journal_title：Scandinavian journal of immunology

authors： Andersson J,Melchers F,Rolink A

更新日期：1995-07-01 00:00:00

abstract：:The cause of ankylosing spondylitis (AS) remains unelucidated. Both genetic and environmental factors are suspected playing an important role in AS development. Peptidyl arginine deiminase type IV (PADI4) is a member of gene family that encodes enzymes responsible for the conversion of arginine to citrulline residues....

journal_title：Scandinavian journal of immunology

authors： Chen R,Wei Y,Cai Q,Duan S,Lin J,Fang M,Lv K,Cheng N,Sun S

更新日期：2010-11-01 00:00:00

abstract：:Exogenously added beta 2-microglobulin (beta 2m) binds to a variety of murine cell types. The 'receptor' for beta 2m has been isolated. The purified 'receptor' comprised a 48,000-dalton chain and occasionally a 25,000-dalton component. Direct crosslinking of beta 2m to the receptor on intact cells gave rise to a singl...

journal_title：Scandinavian journal of immunology

authors： Sege K,Peterson PA

更新日期：1980-01-01 00:00:00

abstract：:To compare the receptor patterns for mitogenic and non-mitogenic substances, surface glycoproteins of human lymphocytes were labelled with the lactoperioxidase-catalysed iodination technique and with a galactose oxidase-tritiated sodium borohydride technique. Labelled cells were detergent-solubilized, and the lysates ...

journal_title：Scandinavian journal of immunology

authors： Skoog VT,Nilsson SF,Weber TH

更新日期：1980-01-01 00:00:00

abstract：:CD172α and CD47 are members of glycoprotein expressed on macrophages and various immune cells, promote immune recognition and T cell stimulation that priming phagocytosis of pathogens and apoptotic bodies and malignant cell. Tumour-releasing immunosuppressive factor promotes tumour growth and transforms the tumour res...

journal_title：Scandinavian journal of immunology

authors： Gautam PK,Acharya A

更新日期：2014-07-01 00:00:00

abstract：:Metabolic reprogramming plays a critical role in the important cellular metabolic alterations that occur during the activation of immune cells to enable them to adapt to the extracellular environment. Here, we review recent studies on how substrate availability and metabolites mediate the signalling pathways that regu...

journal_title：Scandinavian journal of immunology

authors： Qian X,Yang Z,Mao E,Chen E

更新日期：2018-11-01 00:00:00

abstract：:The immunoglobulin (Ig) plasma levels are known to be, at least partially, genetically regulated, but all the genes involved are not known. Interleukin-1 (IL-1) is a potent proinflammatory cytokine able to serve as an adjuvant for immune responses. IL-1alpha gene is polymorphic, and at least one of the polymorphisms h...

journal_title：Scandinavian journal of immunology

authors： Kilpinen S,Laine S,Hulkkonen J,Hurme M

更新日期：2003-03-01 00:00:00

abstract：:The interferon-alpha and -beta (IFN-alpha/beta) producing ability of the two murine dendritic cell (DC) lines D2SC/1 and FSDC was studied. The D2SC/1 cells produced IFN-alpha and -beta when stimulated by herpes simplex virus (HSV), Sendai virus (SV) or by the bacteria Escherichia coli or Staphylococcus aureus Cowan I....

journal_title：Scandinavian journal of immunology

authors： Eloranta ML,Sandberg K,Ricciardi-Castagnoli P,Lindahl M,Alm GV

更新日期：1997-09-01 00:00:00

abstract：:The in vitro immune response of lymphocytes from uraemic patients was studied by comparing the in vitro kinetics of interleukin 2 (IL-2) production, the mitogen-induced proliferative response, and the expression of IL-2 receptors by T lymphocytes. The IL-2 production in 26 uraemic cell cultures decreased significantly...

journal_title：Scandinavian journal of immunology

authors： Langhoff E,Hofmann B,Odum N,Ladefoged J,Platz P,Ryder LP,Svejgaard A

更新日期：1987-01-01 00:00:00

abstract：:Several vaccination studies have been performed in monkeys and humans testing the feasibility of prophylactic and therapeutic immunizations against Helicobacter pylori. The monkey studies showed that immune responses were induced by oral vaccination with the mucosal adjuvant LT (Escherichia coli heat-labile enterotoxi...

journal_title：Scandinavian journal of immunology

authors： Lee CK

更新日期：2001-05-01 00:00:00

abstract：:Sjögren's syndrome is characterized by dryness of the eyes and the mouth due to mononuclear cell infiltration of the lacrimal and salivary glands. The aetiology is unknown but autoimmunity is considered to play a significant role in the pathogenesis. Recent studies have focused on the fact that tear and salivary flow ...

journal_title：Scandinavian journal of immunology

authors： Humphreys-Beher MG,Brayer J,Yamachika S,Peck AB,Jonsson R

更新日期：1999-01-01 00:00:00

abstract：:We have analysed separately the role of B-cell receptor (BCR) stimulation and the soluble second signal in the T-cell-independent type 2 (TI-2) B-cell response. We were able to show that human B cells and macrophages (Mphi) could function together in TI-type microbial response. Interestingly, BCR cross-linking of peri...

journal_title：Scandinavian journal of immunology

authors： Mättö M,Raunio AR,Postila V,Huttunen K,Hirvonen MR,Pelkonen J

更新日期：2008-03-01 00:00:00

abstract：:Myasthenia gravis (MG) and its animal model experimental autoimmune MG (EAMG), are T-cell dependent, antibody-mediated autoimmune disorders. A dual altered peptide ligand (APL) composed of the tandemly arranged two single amino acids analogs of two myasthenogenic peptides, p195-212 and p259-271, was demonstrated to do...

journal_title：Scandinavian journal of immunology

authors： Ben-David H,Venkata Aruna B,Sela M,Mozes E

更新日期：2007-06-01 00:00:00

abstract：:The T-cell regulatory function has been evaluated in lines of mice genetically selected according to the High (H) and Low (L) antibody responsiveness to heterologous erythrocytes. The inhibition of antibody production following CD4+ subset depletion was stronger in L than in H mice. The dose of CD4-specific monoclonal...

journal_title：Scandinavian journal of immunology

authors： Cabrera WH,Siqueira M,Takahashi NS,Ribeiro OG,Araujo LM,Mouton D,Ibanez OM

更新日期：1995-03-01 00:00:00

abstract：:Allograft rejection involves T-cell activation, requiring T-cell receptor interactions with major histocompatibility complex (MHC) molecules and costimulatory signals delivered through the B7-CD28 pathway. We evaluated the effect of blocking this pathway on graft rejection and survival, in a rat experimental model of ...

journal_title：Scandinavian journal of immunology

authors： Kurlberg G,Haglind E,Schön K,Törnqvist H,Lycke N

更新日期：2000-03-01 00:00:00

abstract：:In a previous report the authors demonstrated that acute graft-versus-host disease (GVHD) was associated with pathologic amounts of tumour necrosis factor alpha (TNF-alpha) and the appearance of lipopolysaccharide (LPS) in the blood of GVH reactive mice just prior to death. In this study the authors have investigated ...

journal_title：Scandinavian journal of immunology

authors： Price KS,Nestel FP,Lapp WS

更新日期：1997-03-01 00:00:00

abstract：:Natural killer (NK) cells form part of the vertebrate defence against viruses and tumours, but show only limited specificity. The molecule(s) recognized by NK cells on target cells are at present unknown. Major histocompatibility complex (MHC) class I antigen concentration on target cells is inversely correlated with ...

journal_title：Scandinavian journal of immunology

authors： Müllbacher A,King NJ

更新日期：1989-07-01 00:00:00

abstract：:Cockroaches have been identified as one of the major indoor allergens inducing perennial rhinitis and asthma. Per a 1s are a group of the major allergens from American cockroach. Although Per a 1s are major allergens from American cockroach, factors contributing to the allergenicity of Per a 1s are still poorly define...

journal_title：Scandinavian journal of immunology

authors： He S,Zhang Z,Zhang H,Wei J,Yang L,Yang H,Sun W,Zeng X,Yang P

更新日期：2011-09-01 00:00:00