Kinetic analysis of interleukin 2 (IL-2) production and expression of IL-2 receptors by uraemic and normal lymphocytes.

abstract：:The secretion of interleukin (IL)-1 beta, IL-6 and tumour necrosis factor (TNF)-alpha were compared when freshly isolated autologous monocytes or monocytederived macrophages (MDMs) were co-cultured in vitro with autologous fragment (F)-spheroids established from a series of head and neck squamous cell carcinoma (HNSCC...

journal_title：Scandinavian journal of immunology

authors： Heimdal JH,Aarstad HJ,Olsnes C,Olofsson J

更新日期：2001-02-01 00:00:00

abstract：:Peripheral blood lymphoid subsets expressing either CD45RA or CD29 antigens, were quantified in 30 children and 59 adults with Down Syndrome and appropriate age-matched controls, by dual immunofluorescence and flow cytometry. Down's patients, both adults and children, displayed a significant decrease of CD4+CD45RA+ ce...

journal_title：Scandinavian journal of immunology

authors： Barrena MJ,Echaniz P,Garcia-Serrano C,Cuadrado E

更新日期：1993-10-01 00:00:00

abstract：:The average frequency of cytotoxic precursor cells in DBA/2 lymph node cell preparations reactive to the syngeneic tumour P815 has been determined as 1 in 2000. This frequency is similar to the precursor frequency for an allogeneic tumour EL-4. The normal lack of response of DBA/2 lymph node cells to the syngeneic tum...

journal_title：Scandinavian journal of immunology

authors： Warren HS,Lafferty KJ

更新日期：1979-01-01 00:00:00

abstract：:Monoclonal anti-HLA-DR antibodies inhibited the production of interleukin-2 (IL-2) when added from the initiation of autologous (AMLR) and allogeneic (MLR) mixed lymphocyte reactions, but not 60 h later. The inhibitory activity of the anti-DR sera became apparent 8 h after initiation of the cultures and was maintained...

journal_title：Scandinavian journal of immunology

authors： Palacios R

更新日期：1981-09-01 00:00:00

abstract：:Inflammatory bowel diseases (IBD) are a group of chronic recurrent gastrointestinal inflammatory diseases, including ulcerative colitis (UC), Crohn's disease (CD) and IBD unclassified. The pathogenesis may be related to the mucosal immune dysfunction in genetically susceptible hosts affected by environmental factors. ...

journal_title：Scandinavian journal of immunology

authors： Zhang X,Wang S,Ding X,Guo J,Tian Z

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Both C1-inhibitor (C1-INH) and antibodies against the CD18 adhesion molecule have been shown to reduce ischaemia-reperfusion injuries. The objective of this study was to investigate the effect of increased ischaemia times and to determine whether inhibiting C1 or blocking the CD18 function was protective in ...

journal_title：Scandinavian journal of immunology

authors： Nielsen EW,Mollnes TE,Harlan JM,Winn RK

更新日期：2002-12-01 00:00:00

abstract：:The authors have established a new immunodeficient mouse strain on the genetic background of the diabetes prone non-obese diabetic (NOD) mouse. A deletion mutant of the RAG-2 gene was back crossed 10 generations onto the NOD/Bom strain background. The homozygous NODrag-2-/- mice lack functionally mature B and T lympho...

journal_title：Scandinavian journal of immunology

authors： Söderstrøm I,Bergman ML,Colucci F,Lejon K,Bergqvist I,Holmberg D

更新日期：1996-05-01 00:00:00

abstract：:Gangliosides are complex glycosphingolipids, which exert immune-modulating effects on various cell types. Ganglioside GD(3) and GM(3) are the predominant gangliosides of human breast milk but during the early phase of lactation, the content of GD(3) decreases while GM(3) increases. The biological value of gangliosides...

journal_title：Scandinavian journal of immunology

authors： Brønnum H,Seested T,Hellgren LI,Brix S,Frøkiaer H

更新日期：2005-06-01 00:00:00

abstract：:22q11.2 deletion syndrome is the commonest chromosome deletion syndrome. 22q11.2 deletion may result in variable clinical phenotypes which may differ even between patients with identical deletions. Abnormal pharyngeal arch development results in defects in the development of the parathyroid glands, thymus and conotrun...

journal_title：Scandinavian journal of immunology

authors： McLean-Tooke A,Spickett GP,Gennery AR

更新日期：2007-07-01 00:00:00

abstract：:Human lymphocytes were cultured under different conditions to determine the effects of technical variations on the response to pokeweed mitogen (PWM) and Staphylococcus aureus as measured by (a) quantitation of immunoglobulins (Ig) in the culture supernatants and (b) enumeration of Ig-secreting cells (ISC) by a revers...

journal_title：Scandinavian journal of immunology

authors： Munoz J,Pryjma J,Fudenberg HH,Virella G

更新日期：1980-01-01 00:00:00

abstract：:Allogeneic chimaeras that utilize C.B-17 SCID mice (H-2d) as recipients of MHC mismatched bone marrow from C57B1/6 (H-2b) or SJL/J (H-2s) mice have been used to provide experimental evidence demonstrating the necessity for a direct interaction between an effector T helper and the cytotoxic T-cell precursor in order to...

journal_title：Scandinavian journal of immunology

authors： Lin Y,Langman R,Cohn M

更新日期：1992-05-01 00:00:00

abstract：:In this review, we summarize and discuss some key findings from the study of naturally occurring autoantibodies. The B-cell compartment of the immune system appears to recognize almost all endogenous and environmental antigens. This ability is accomplished principally through autopolyreactive humoral and cellular immu...

journal_title：Scandinavian journal of immunology

authors： Avrameas S

更新日期：2016-04-01 00:00:00

abstract：:In this study, we discuss the use of glycopeptides containing tumour-associated carbohydrate antigens (TACA) as preventive vaccines for carcinomas. The results of our recent studies suggest that CD8(+) cytotoxic T cells are capable of recognizing small TACA in a conventional class I MHC-restricted fashion. TACA-specif...

journal_title：Scandinavian journal of immunology

authors： Franco A

更新日期：2005-05-01 00:00:00

abstract：:Non-specific antibody production usually accompanies the T-cell-regulated B-cell response. In this paper the mechanisms involved in non-MHC-restricted T-B-cell interaction were studied. As previously shown for NK cells, activated B cells induce IFN-gamma and TNF alpha production in non-MHC-restricted cytotoxic T lymph...

journal_title：Scandinavian journal of immunology

authors： Becker JC,Dummer R,Von Wussow P,Burg G,Schmidt RE

更新日期：1992-08-01 00:00:00

abstract：:Phagocytosis of Staphylococcus aureus by human polymorphonuclear leucocytes (PMN) on the surface of endothelial cells is accompanied by adherence of the PMN to the endothelial surface and detachment of the endothelial cells from the culture monolayer. We studied the role of the leucocyte adherence-related glycoprotein...

journal_title：Scandinavian journal of immunology

authors： Vandenbroucke-Grauls CM,Thijssen HM,Tetteroo PA,Rozemuller E,Verhoef J

更新日期：1989-07-01 00:00:00

abstract：:Alterations in duodenal Ig-producing cells induced by two oral cholera vaccinations were studied by two-colour immunofluorescence in mucosal tissue sections from adults with selective IgA deficiency (IgAD), either with (n = 7) or without (n = 9) frequent infections, infection-prone patients with combined IgAD and IgG ...

journal_title：Scandinavian journal of immunology

authors： Nilssen DE,Friman V,Theman K,Björkander J,Kilander A,Holmgren J,Hanson LA,Brandtzaeg P

更新日期：1993-08-01 00:00:00

abstract：:The intestinal microbiota is important for tolerance induction through mucosal immunological responses. The composition of the gut microbiota of an infant is affected by environmental factors such as diet, disease and antibiotic treatment. However, already in utero, these environmental factors can affect the immunolog...

journal_title：Scandinavian journal of immunology

authors： Tormo-Badia N,Håkansson Å,Vasudevan K,Molin G,Ahrné S,Cilio CM

更新日期：2014-10-01 00:00:00

abstract：:CD4+ T cells lacking the costimulatory molecule CD28 have been described both in elderly individuals and in chronic inflammatory disorders, one being rheumatoid arthritis (RA). We, in this study, provide a comprehensive characterization of cell surface markers on and function of such CD28nullCD4+ T cells, as well as c...

journal_title：Scandinavian journal of immunology

authors： Fasth AE,Cao D,van Vollenhoven R,Trollmo C,Malmström V

更新日期：2004-07-01 00:00:00

abstract：:A Gross virus induced rat T cell lymphoma G1-Tc1 and a Moloney virus induced mouse T cell lymphoma YAC-1 are shown to exert a strong cytotoxic activity against rat yolk sac tumours but not to various types of rat, mouse or human normal cells or tumour cell lines including carcinomas, sarcomas, lymphomas and gliomas. B...

journal_title：Scandinavian journal of immunology

authors： Lindvall M,Eriksson H,Hedlund G,Sjögren HO

更新日期：1997-11-01 00:00:00

abstract：:Amyloid was extracted from the liver of a horse that had developed amyloidosis after being used for several years for the production of antibodies to bacterial antigens. The amyloid fibrils were shown to be of the AA type. Two AA proteins with molecular weights of 9000 and 11,000 and with identical partial N-terminal ...

journal_title：Scandinavian journal of immunology

authors： Husebekk A,Husby G,Sletten K,Marhaug G,Nordstoga K

更新日期：1986-06-01 00:00:00

abstract：:Several enveloped viruses, particularly some RNA viruses, have high rates of mutation or replication, which can make them virulent pathogens in humans and other mammals. A proposed treatment could use synthesized proteins to mask pathogenic viral surface proteins to quickly induce an immune attack on specific envelope...

journal_title：Scandinavian journal of immunology

authors： Roe K

更新日期：2020-09-01 00:00:00

abstract：:Myeloid dendritic cells (MyDCs), prime stimulators of antigen-specific immunity, can serve as one of the major reservoirs for human immunodeficiency virus type-1 (HIV-1). Utilizing mature monocyte-derived MyDCs generated with granulocyte/macrophage colony-stimulating factor, interleukin-4, and tumour necrosis factor-a...

journal_title：Scandinavian journal of immunology

authors： Gieseler RK,Marquitan G,Hahn MJ,Perdon LA,Driessen WH,Sullivan SM,Scolaro MJ

更新日期：2004-05-01 00:00:00

abstract：:In a group of 20 patients with asymptomatic paraproteinemia, as judged after at least 3 years of follow-up, the primary and secondary antibody response to Helix pomatia hemocyanin (HPH) was defective as compared with the response in controls. The class of antibody was assessed by mercaptoethanol (ME) treatment of seru...

journal_title：Scandinavian journal of immunology

authors： Weits J,de Gast GC,The TH,Marrink J,Mandema E

更新日期：1976-01-01 00:00:00

abstract：:Mice homologous for the alymphoplasia mutation (aly) show the systemic absence of secondary lymphoid tissues, with disorganized splenic architecture, including the absence of the germinal centre and follicular dendritic cells. In this study, we examined the influence of defects of gut-associated lymphoid tissue (GALT)...

journal_title：Scandinavian journal of immunology

authors： Morimoto M,Yamauchi Y,Shinkawa S,Ishiwata K,Hayashi T

更新日期：2006-05-01 00:00:00

abstract：:The majority of patients with myasthenia gravis were shown to have T and B cells specific for a beta-bungarotoxin binding protein, presynaptic membrane receptor (PsmR). Such autoreactive T cells may be subdivided into different subsets according to the pattern of cytokine production. In this study the authors examined...

journal_title：Scandinavian journal of immunology

authors： Yi Q,Pirskanen R,Lefvert AK

更新日期：1996-01-01 00:00:00

abstract：:We have examined the frequencies of T gamma delta cells in blood, synovial fluids, and synovial membranes of patients with rheumatoid arthritis (RA) and in blood from age-matched controls. Immunocytochemical and immunohistochemical techniques were used with monoclonal antibodies BB3 and A13 to define a major and minor...

journal_title：Scandinavian journal of immunology

authors： Smith MD,Bröker B,Moretta L,Ciccone E,Grossi CE,Edwards JC,Yüksel F,Colaco B,Worman C,Mackenzie L

更新日期：1990-12-01 00:00:00

abstract：:The frequency of HLA DQA1, DQB1, and DPB1 mismatches was evaluated in 110 HLA class I- and DRB1-matched, unrelated pairs who were tested in mixed lymphocyte culture (MLC) in connection with a potential allogeneic bone-marrow transplantation between unrelated persons. After typing of the DQA1, DQB1, and DPB1 genes retr...

journal_title：Scandinavian journal of immunology

authors： Partanen J,Koskimies S

更新日期：1994-03-01 00:00:00

abstract：:Native agarose beads (diameter 5-10 micron), activators of the alternative complement pathway, are slowly phagocytosed when incubated with human monocytes cultured under serum-free conditions. Agarose beads preincubated with monocyte cultures and then transferred to new cultures are more easily phagocytosed than nativ...

journal_title：Scandinavian journal of immunology

authors： Hetland G,Eskeland T

更新日期：1986-03-01 00:00:00

abstract：:The relationship between the so-called natural interferon-alpha (IFN-alpha) producing cell (IPC), stimulated to produce IFN-alpha by herpes simplex virus type 1 (HSV), and of dendritic cells (DC) in peripheral blood leucocytes was investigated. The simultaneous expression of cell surface antigens and intracellular IFN...

journal_title：Scandinavian journal of immunology

authors： Svensson H,Johannisson A,Nikkilä T,Alm GV,Cederblad B

更新日期：1996-08-01 00:00:00

abstract：:CD27 has been found to be expressed on somatically mutated B cells and is thus a positive marker for memory B cells in peripheral blood (PB). Since abnormal immunogloblin (Ig) production is characteristic of the autoimmune diseases primary Sjögren's syndrome (pSS) and rheumatoid arthritis (RA), we have analyzed in det...

journal_title：Scandinavian journal of immunology

authors： Bohnhorst JO,Thoen JE,Natvig JB,Thompson KM

更新日期：2001-10-01 00:00:00