Characterization of amyloid protein AA and its serum precursor SAA in the horse.

abstract：:Coexistence of amyloid fibril protein AA and homogeneous immunoglobulin light-chain fragments was found in the isolated amyloid fibrils of two patients with amyloidosis secondary to rheumatoid arthritis. The light-chain amyloid fibril protein showed antigenic identity with a light-chain amyloid from a patient with pri...

journal_title：Scandinavian journal of immunology

authors： Westermark P,Natvig JB,Anders RF,Sletten K,Husby G

更新日期：1976-01-01 00:00:00

abstract：:The role of macrophages in the in vitro response of mouse spleen cells to the insolubilized, T-independent antigen trinitrophenylated polyacrylamide (TNP-PAA) is demonstrated by the following points. The response is abolished by filtration on Sephadex G-10 and can be restored by the addition of splenic adherent cells,...

journal_title：Scandinavian journal of immunology

authors： Duclos H,Galanaud P,Maillot MC,Crevon MC,Dormont J

更新日期：1979-01-01 00:00:00

abstract：:Hypoxia is a prominent microenvironment feature in a range of disorders including cancer, rheumatoid arthritis (RA), atherosclerosis, inflammatory bowel disease (IBD), infection and obesity. Hypoxia promotes biological functions of fibroblast-like synoviocytes via regulating hypoxia-inducible factor 1α (HIF1α). Dysreg...

journal_title：Scandinavian journal of immunology

authors： Yu R,Li C,Sun L,Jian L,Ma Z,Zhao J,Liu X

更新日期：2018-04-01 00:00:00

abstract：:Cutaneous lupus erythematosus (CLE) is an autoimmune disease with a broad range of cutaneous manifestations. In skin lesions of CLE, keratinocytes primarily undergo apoptosis. Interferon-κ(IFN-κ) is belonged to type I interferons (type I IFNs) and is selectively produced by keratinocytes. Recently, keratinocytes selec...

journal_title：Scandinavian journal of immunology

authors： Zhou X,Yan J,Lu Q,Zhou H,Fan L

更新日期：2021-01-01 00:00:00

abstract：:Telomeres are unique terminal chromosomal structures, the length of which has been shown to decrease with cell division in vitro and with increased age in vivo for human somatic cells. In human immunodeficiency virus (HIV)-1 infection, decrease of telomere length is primarily found in CD8+ T cells, and not in CD4+ T c...

journal_title：Scandinavian journal of immunology

authors： Aladdin H,Ullum H,Schjerling P,Skov Jensen M,Dam Nielsen S,Mathiesen L,Gerstoft J,Skinhøj P,Klarlund Pedersen B

更新日期：2000-08-01 00:00:00

abstract：:Transgenic techniques in inbred mouse strains are powerful tools to investigate the specific roles of genes in biological pathways and disease models. However, there is increasing concern over the influence of a variable genetic background in such experiments. To date there have been few investigations of the immunolo...

journal_title：Scandinavian journal of immunology

authors： Johansson AC,Vestberg M,Holmdahl R

更新日期：2000-07-01 00:00:00

abstract：:In vitro lymphocyte stimulation was performed on peripheral blood lymphocytes from 48 leprosy patients, 15 healthy contacts of leprosy patients, and 16 normal controls who lived in a leprosy-free area and who had not been exposed to leprosy. Tuberculin PPD and an antigen fraction. MLW 1, prepared from M. leprae, were ...

journal_title：Scandinavian journal of immunology

authors： Closs O,Reitan LJ,Negassi K,Harboe M,Belehu A

更新日期：1982-08-01 00:00:00

abstract：:ESAT-6 is a protein produced by virulent Mycobacterium tuberculosis but absent in Mycobacterium bovis bacillus Calmette-Guerin (BCG) and is considered as a promising vaccine subunit against tuberculosis. The protective efficacy of a new strategy based on the combination of DNA vaccine encoding ESAT-6 (DNA-E6) and BCG ...

journal_title：Scandinavian journal of immunology

authors： Fan X,Gao Q,Fu R

更新日期：2007-11-01 00:00:00

abstract：:Antigen fragments, biologically degraded by antigen-presenting cells (APC), combine with Ia positive moieties (IPM) to stimulate antigen-specific T lymphocyte lines. The main objective of this study was to evaluate whether this interaction was determined by the major histocompatibility complex (MHC) genotype of the AP...

journal_title：Scandinavian journal of immunology

authors： Friedman A,Lider O,Beraud E,Cohen IR

更新日期：1989-06-01 00:00:00

abstract：:Immunoglobulin G (IgG) is important in clearance and recognition of previously presented antigens and after activation, IgGs can interact with the Fc gamma receptors (FcγRs) on haematopoietic cells, including bone-resorbing osteoclasts. The pathogenicity of IgG, that is the ability to elicit stimulatory effects via Fc...

journal_title：Scandinavian journal of immunology

authors： Sehic E,Westerlund A,Lagerquist MK,Lerner UH,Carlsten H,Henning P,Engdahl C

更新日期：2020-12-15 00:00:00

abstract：:Using cytotoxic effector cells of different anti-H-2 specificities, new cell-mediated lympholysis targets, normally undetected on Meth. A tumour cells, were shown after passage with vaccinia or Moloney virus. The H-2d CML targets on Meth. A cells recognized by B10.BR anti-B10.D2 effector cells were presented only afte...

journal_title：Scandinavian journal of immunology

authors： Matossian-Rogers A,Garrido F,Festenstein H

更新日期：1977-01-01 00:00:00

abstract：:Psoriasis is a T-cell mediated inflammatory skin disease which has been associated with group A, beta-haemolytic streptococcal infections. Four 20 a.a. long M6-peptides sharing 5-6 a.a. sequences with human epidermal keratins were identified. To investigate the role of potentially cross-reactive T cells in the pathoge...

journal_title：Scandinavian journal of immunology

authors： Sigmundsdottir H,Sigurgeirsson B,Troye-Blomberg M,Good MF,Valdimarsson H,Jonsdottir I

更新日期：1997-06-01 00:00:00

abstract：:The main object of this study was to see whether or not chromatin constituents are present in cell membranes. The binding of antinuclear antibodies (ANA) to plasma membranes of leucocytes was studied by using autoantibodies and induced antibodies to different histones and histone peptides, and autoantibodies to double...

journal_title：Scandinavian journal of immunology

authors： Rekvig OP

更新日期：1989-01-01 00:00:00

abstract：:Non-specific antibody production usually accompanies the T-cell-regulated B-cell response. In this paper the mechanisms involved in non-MHC-restricted T-B-cell interaction were studied. As previously shown for NK cells, activated B cells induce IFN-gamma and TNF alpha production in non-MHC-restricted cytotoxic T lymph...

journal_title：Scandinavian journal of immunology

authors： Becker JC,Dummer R,Von Wussow P,Burg G,Schmidt RE

更新日期：1992-08-01 00:00:00

abstract：:By using PCR, we have found previously that differences in T cell receptor alpha/beta chain variable region (TCR alpha/beta) gene expression in lymph nodes (LN) existed between susceptible and resistant mice following anterior chamber (AC) inoculation with herpes simplex virus (HSV). We now report and compare the immu...

journal_title：Scandinavian journal of immunology

authors： Arrunategui-Correa VR,Dutt JE,Foster CS

更新日期：1995-09-01 00:00:00

abstract：:In the absence of an affordable conjugate meningococcal vaccine, mass vaccination campaigns with polysaccharide vaccines are the means to control meningitis epidemics in sub-Saharan Africa. Facing global vaccine shortage, the use of reduced doses, which have been shown to be protective by serum bactericidal activity, ...

journal_title：Scandinavian journal of immunology

authors： Bårnes GK,Naess LM,Rosenqvist E,Guerin PJ,Caugant DA,Fractional Doses Vaccine Study Group.

更新日期：2011-07-01 00:00:00

abstract：:We have sequenced the variable heavy chain regions of a number of VH4-21 encoded monoclonal IgM anti-Rh(D) antibodies produced in response to deliberate immunization. These were compared with the sequences of similarly encoded IgM anti-I cold agglutinins (CA) derived from patients with lympho-proliferative diseases. T...

journal_title：Scandinavian journal of immunology

authors： Børretzen M,Chapman C,Stevenson FK,Natvig JB,Thompson KM

更新日期：1995-07-01 00:00:00

abstract：:Previously reported experiments suggested that an esterase or a protease, or both, might participate in the expression of human leukocyte migration inhibitory factor (LIF). To clarify this further, a wide variety of simple ester were tested for the ability to protect LIF against inactivation by the serine esterase inh...

journal_title：Scandinavian journal of immunology

authors： Bendtzen K

更新日期：1977-01-01 00:00:00

abstract：:Human natural killer (NK) cells are able to adhere to xenogeneic porcine endothelial cells (EC) and evidence from in vitro studies as well as animal models suggests a potential role for NK cells in the cellular recognition and damage of porcine xenogeneic tissues. One possible explanation for the observed NK cell-medi...

journal_title：Scandinavian journal of immunology

authors： Schneider MK,Forte P,Seebach JD

更新日期：2001-07-01 00:00:00

abstract：:The aim of this study was to examine whether the unresponsiveness of MHC class I-negative subclones of the EL4 thymoma to CD3 cross-linking can be restored by transfection of class I genes into the H-2-negative cells. Cell activation experiments with selected MHC class I-negative subclones and H-2b- and H-2Ld-positive...

journal_title：Scandinavian journal of immunology

authors： Claesson MH,Dissing S,Plesner T,Sturmhöfel K,Brams P

更新日期：1990-07-01 00:00:00

abstract：:Antigen uptake and the following maturation of dendritic cells (DCs) are pivotal to the initiation of specific antimicrobial immune responses. DCs also play an important role in the recruitment and activation of the cells of the innate immune system. We have examined the interactions of DCs with Borrelia burgdorferi t...

journal_title：Scandinavian journal of immunology

authors： Suhonen J,Komi J,Soukka J,Lassila O,Viljanen MK

更新日期：2003-07-01 00:00:00

abstract：:We investigated interferon (IFN) production by peripheral blood mononuclear cells from four patients with chronic OKT4 T-lymphocytic leukaemia and three patients with abnormal expansions of granular lymphocytes. No spontaneous production of IFN-gamma was found in supernatants of cultures from both patients and normal ...

journal_title：Scandinavian journal of immunology

authors： Pandolfi F,Capobianchi M,Matricardi P,Facchini J,Bonomo G,De Rossi G,Semenzato G,Fiorilli M,Dianzani F,Aiuti F

更新日期：1985-04-01 00:00:00

abstract：:Haematopoietic precursors first colonizing the avian embryonic thymus are derived from the intraembryonic sites located around the dorsal aortae. These intraembryonic precursors have previously been demonstrated to include cells that harbour T-cell progenitor capacity and express the Ikaros transcription factor, known...

journal_title：Scandinavian journal of immunology

authors： Liippo J,Koskela K,Lassila O

更新日期：2000-11-01 00:00:00

abstract：:Human peripheral lymphocytes were cultivated in soft agar or agarose, containing 3H-thymidine or bromodeoxyuridine (BrdU), which is an analogue of thymidine readily incorporated into deoxyribonucleic acid by lymphocytes. Colonies were isolated and analysed by autoradiography or stained with the fluorescence-plus-Giems...

journal_title：Scandinavian journal of immunology

authors： Lindahl-Kiessling K,Karlberg I

更新日期：1981-05-01 00:00:00

abstract：:L-selectin, a cell surface glycoprotein expressed on lymphocytes, granulocytes, and monocytes, has been implicated in lymphocyte homing and extravasation of phagocytic leukocytes into areas of inflammation. Considerable differences of L-selectin expression among various individuals has been reported, with clinical cor...

journal_title：Scandinavian journal of immunology

authors： Stibenz D,Bührer C

更新日期：1994-01-01 00:00:00

abstract：:Spleen cells from mice exposed to 500 rad sublethal whole-body irradiation before immunization with 100 x 10(6) allogeneic spleen cells exhibited an enhanced cytolytic T-lymphocyte (CTL) activity. In contrast, this treatment completely abrogated the humoral alloantibody response, as measured by complement-mediated lys...

journal_title：Scandinavian journal of immunology

authors： Engers HD,Louis J

更新日期：1979-01-01 00:00:00

abstract：:To study the role of Natural Killer (NK) cells in Leishmania infection, peritoneal macrophages from BALB/c mice were infected with Leishmania (Leishmania) amazonensis promastigotes and incubated with interleukin-2 (IL-2)-activated NK (A-NK) cells at different ratios of A-NK cells to infected macrophages (5:1, 1:1, 0.2...

journal_title：Scandinavian journal of immunology

authors： Aranha FC,Ribeiro U Jr,Basse P,Corbett CE,Laurenti MD

更新日期：2005-10-01 00:00:00

abstract：:We have reported previously that subclinical prolonged mild T helper (Th) 1-dependent autoimmune insulitis with impaired glucose tolerance in wealing DBA/1J mice, which is induced by the combined effects of reovirus type 2 (Reo-2) and synthetic 20-base oligodeoxynucleotides with CpG motifs (CpG ODN) (control mice). Co...

journal_title：Scandinavian journal of immunology

authors： Hayashi T,Hasegawa K,Sasaki Y,Onodera T

更新日期：2006-02-01 00:00:00

abstract：:Gangliosides are complex glycosphingolipids, which exert immune-modulating effects on various cell types. Ganglioside GD(3) and GM(3) are the predominant gangliosides of human breast milk but during the early phase of lactation, the content of GD(3) decreases while GM(3) increases. The biological value of gangliosides...

journal_title：Scandinavian journal of immunology

authors： Brønnum H,Seested T,Hellgren LI,Brix S,Frøkiaer H

更新日期：2005-06-01 00:00:00

abstract：:Interferon gamma (IFN-gamma) production as a measure of cellular sensitization was studied by detection of the cytokine in culture supernatant by enzyme immunoassay (EIA) and by measuring cellular mRNA using the reverse transcriptase polymerase chain reaction (RT-PCR) method. These assays were compared to the standard...

journal_title：Scandinavian journal of immunology

authors： Halminen M,Klemetti P,Vaarala O,Hurme M,Ilonen J

更新日期：1997-10-01 00:00:00