Target cell lysis by natural killer cells is influenced by beta 2-microglobulin expression.

abstract：:T cells from immune guinea-pigs produce clusters in vitro with macrophages pulsed with soluble protein antigens. The formation of clusters is antigen-specific. Time-lapse cinephotomicrography was used to study the sequence of events leading to cluster formation and the kinetics of already formed clusters. The central ...

journal_title：Scandinavian journal of immunology

authors： Petri J,Braendstrup O,Werdelin O

更新日期：1979-01-01 00:00:00

abstract：:The aim of this study was to investigate T-T cell interactions that may be involved in the pathogenesis of chronic synovitis. Two CD4+ T-cell clones, termed N16 and N18, sharing similar cytokine profiles were isolated from the synovial tissue of a patient with rheumatoid arthritis. Activated N16 cells induced prolifer...

journal_title：Scandinavian journal of immunology

authors： Van Laar JM,Miltenburg AM,De Kuiper P,Daha MR,De Vries RR,Breedveld FC

更新日期：1993-06-01 00:00:00

abstract：:Human CD26 has dipeptidyl peptidase-4 (DPP IV) enzyme activity and binds to adenosine deaminase (ADA). CD26 is costimulatory for lymphocytes and has a circulating soluble form (sCD26). DPP IV enzyme inhibition is a new successful type 2 diabetes therapy. We examined whether the ADA binding and catalytic functions of s...

journal_title：Scandinavian journal of immunology

authors： Yu DM,Slaitini L,Gysbers V,Riekhoff AG,Kähne T,Knott HM,De Meester I,Abbott CA,McCaughan GW,Gorrell MD

更新日期：2011-02-01 00:00:00

abstract：:Psoriasis is a T-cell mediated inflammatory skin disease which has been associated with group A, beta-haemolytic streptococcal infections. Four 20 a.a. long M6-peptides sharing 5-6 a.a. sequences with human epidermal keratins were identified. To investigate the role of potentially cross-reactive T cells in the pathoge...

journal_title：Scandinavian journal of immunology

authors： Sigmundsdottir H,Sigurgeirsson B,Troye-Blomberg M,Good MF,Valdimarsson H,Jonsdottir I

更新日期：1997-06-01 00:00:00

abstract：:We examined the effects of CD86 ligation on surface densities of CD80 on activated B cells. For this, splenic B cells where CD86 levels had been enhanced upon anti-immunoglobulin M (IgM) treatment were employed. Incubation of such CD86-expressing B cells with anti-CD86 monoclonal antibody (MoAb) resulted in a marked u...

journal_title：Scandinavian journal of immunology

authors： Sahoo NC,Rao KV,Natarajan K

更新日期：2002-06-01 00:00:00

abstract：:The binding of a 34-kDa (mol. wt.) acylpoly(1,3)galactoside (APG) extracted from a membrane proteoglycan of Klebsiella pneumoniae to human blood leucocytes was investigated. APG is made of a long poly(1,3)galactose chain, a core-like region and a lipid moiety which comprises two glucosamine residues bound to a phospha...

journal_title：Scandinavian journal of immunology

authors： Hmama Z,Kouassi E,Panaye G,Delassan S,Normier G,Binz H,Revillard JP

更新日期：1992-07-01 00:00:00

abstract：:Lymphatic filariasis, a mosquito-borne parasitic disease, affects more than 120 million people worldwide. Vaccination for filariasis by targeting different stages of the parasite will be a boon to the existing MDA efforts of WHO which required repeated administration of the drug to reduce the infection level and susta...

journal_title：Scandinavian journal of immunology

authors： Anugraha G,Madhumathi J,Prince PR,Prita PJ,Khatri VK,Amdare NP,Reddy MV,Kaliraj P

更新日期：2015-10-01 00:00:00

abstract：:Foot-and-mouth disease (FMD) caused by FMD virus (FMDV) is a major health and economic problem in the farming industry. Vaccination of livestock against this highly infectious viral disease is crucial, and inactivated FMD vaccine has been effective at controlling infection. However, accumulated data show that the inac...

journal_title：Scandinavian journal of immunology

authors： Kang J,Zuo Y,Guo Q,Wang H,Liu Q,Liu Q,Xia G,Kang Y

更新日期：2015-11-01 00:00:00

abstract：:Drainage of the thoracic duct resulted in a decrease in the IgA level in rat bile, but at the same time there was an increase in both the total IgM level and the specific IgM antibody activity to Escherichia coli 06 in the bile of animals immunized in the Peyer's patches with these bacteria. The increase in total IgM ...

journal_title：Scandinavian journal of immunology

authors： Dahlgren UI,Ahlstedt S,Hanson LA

更新日期：1986-11-01 00:00:00

abstract：:Crohn's disease (CD) is a chronic inflammatory disease of the gastrointestinal tract that leads to substantial suffering for millions of patients. In some patients, the chronic inflammation leads to remodelling of the extracellular matrix and fibrosis. Fibrosis, in combination with expansion of smooth muscle layers, l...

journal_title：Scandinavian journal of immunology

authors： Alfredsson J,Wick MJ

更新日期：2020-12-01 00:00:00

abstract：:Human peripheral blood monocyte subsets with and without Fc receptor for human IgG are known to suppress (FcR+) and enhance (FcR-) pokeweed mitogen-induced polyclonal immunoglobulin synthesis in vitro. The ability of these subsets to modulate immunoglobulin production in the presence or absence of OKT8+ T cells and un...

journal_title：Scandinavian journal of immunology

authors： Pryjma J,Flad HD,Gruber M,Ernst M

更新日期：1986-07-01 00:00:00

abstract：:Development of type-II collagen (CII)-induced arthritis (CIA) is dependent on a T-cell mediated activation of autoreactive B cells. However, it is still unclear if B cells can present CII to T cells. To investigate the role of B cells as antigen-presenting cells (APCs) for CII, we purified B cells from lymph nodes of ...

journal_title：Scandinavian journal of immunology

authors： Holmdahl M,Vestberg M,Holmdahl R

更新日期：2002-04-01 00:00:00

abstract：:The cause of ankylosing spondylitis (AS) remains unelucidated. Both genetic and environmental factors are suspected playing an important role in AS development. Peptidyl arginine deiminase type IV (PADI4) is a member of gene family that encodes enzymes responsible for the conversion of arginine to citrulline residues....

journal_title：Scandinavian journal of immunology

authors： Chen R,Wei Y,Cai Q,Duan S,Lin J,Fang M,Lv K,Cheng N,Sun S

更新日期：2010-11-01 00:00:00

abstract：:The detection of mRNA in the murine model of tuberculosis for key cytokines involved in protective immunity in the lung tissues revealed a much faster emergence of the interferon (IFN)-gamma response in the intravenous route than in the aerosol route of inoculation. This slower response in the lungs was associated wit...

journal_title：Scandinavian journal of immunology

authors： Cardona PJ,Cooper A,Luquín M,Ariza A,Filipo F,Orme IM,Ausina V

更新日期：1999-04-01 00:00:00

abstract：:The humoral response against the bacterial polysaccharide antigen alpha(1-->3) dextran (Dex) is controlled by J558 idiotype-(Id) specific T cells. These T cells of which the cell clone 178-4 Ts is a representative by all relevant criteria, recognize J558 Id-bearing B cells in an I-Ed-restricted manner. Costimulation v...

journal_title：Scandinavian journal of immunology

authors： Rademaekers A,Specht C,Kölsch E

更新日期：2001-03-01 00:00:00

abstract：:The homogenates of amyloid-laden spleens prepared from CBA mice were analysed by SDS-PAGE and immunoblotting employing rat anti-murine monoclonal antibody, MSA 4-26. The results showed that the precursor of amyloid A protein (AA), serum amyloid A protein 2 (SAA2), and SAA intermediates with molecular weights of 10,000...

journal_title：Scandinavian journal of immunology

authors： Shiroo M,Kawahara E,Nakanishi I,Migita S

更新日期：1987-12-01 00:00:00

abstract：:The chemotactic activity in serum, defined as the attractant effect of serum on the migration of neutrophil granulocytes (PMN) has been investigated for the purpose of characterizing the major chemotactic factors in serum as measured by the leading-front technique, using a modified Boyden chamber. The chemotactic acti...

journal_title：Scandinavian journal of immunology

authors： Håkansson L,Venge P

更新日期：1984-01-01 00:00:00

abstract：:alpha 2-macroglobulin (alpha 2M) preparations purified from the plasma of healthy persons and gastric carcinoma patients were further analysed by immunochemical techniques. It was found that only alpha 2M from the plasma of gastric carcinoma patients gave a positive reaction with E-receptor sheep antiserum in rocket i...

journal_title：Scandinavian journal of immunology

authors： Smorodin EP,Kurtenkoy OA

更新日期：1991-06-01 00:00:00

abstract：:We have studied the interaction of mitogenic lectins such as phytohaemagglutinin (PHA) and concanavalin A (Con A) with both surface molecules which, by the use of monoclonal antibodies, are known to trigger T-cell mitogenesis. Monoclonal antibodies recognizing the T-lymphocyte receptor for antigen (Ti) and/or its asso...

journal_title：Scandinavian journal of immunology

authors： Leca G,Boumsell L,Fabbi M,Reinherz EL,Kanellopoulos JM

更新日期：1986-05-01 00:00:00

abstract：:RNA silencing is an efficient biochemical tool for gene knock downs as well as physiological phenomenon playing a major role in diverse biological processes. Recent knowledge suggests that the same protein families which mediate the experimental RNA interference (RNAi) in the fruit fly Drosophila melanogaster cells al...

journal_title：Scandinavian journal of immunology

authors： Ulvila J,Hultmark D,Rämet M

更新日期：2010-03-01 00:00:00

abstract：:Rat AgB transplantation antigens were isolated after papain digestion of spleens from the inbred strain Hooded Lister. Both subunits of the AgB antigens were present in the purified material. Some physical characteristics of the antigens have been determined. An antiserum, raised in a rabbit, against the purified mate...

journal_title：Scandinavian journal of immunology

authors： Kvist S,Eriksson U,Peterson PA

更新日期：1980-01-01 00:00:00

abstract：:Bacterial DNA differs from mammalian DNA by the presence of unmethylated cytosine-phosphate-guanosine (CpG) motifs. The immunostimulatory properties of a DNA vaccine have been suspected to be associated with these motifs. The aim of this study was to assess the inactivation of the immunostimulatory potential of a plas...

journal_title：Scandinavian journal of immunology

authors： Cornélie S,Poulain-Godefroy O,Lund C,Vendeville C,Ban E,Capron M,Riveau G

更新日期：2004-02-01 00:00:00

abstract：:T lymphocytes are activated by the interaction between the T-cell antigen receptor (TCR) and peptides presented by major histocompatibility complex (MHC) molecules. The avidity of this TCR-pMHC interaction is very low. Therefore, several hypotheses have been put forward to explain how T cells become specifically activ...

journal_title：Scandinavian journal of immunology

authors： Rubin B,Knibiehler M,Gairin JE

更新日期：2007-08-01 00:00:00

abstract：:The specificity of the Fcgamma receptors in normal spleen and liver and in malignant tissues was studied using hemadsorption to cryostat sections. Indicator cells (EA) were sheep erythrocytes (E) sensitized with rabbit IgG antibody (A). The binding of EA to sections of normal and malignant tissues was inhibited by poo...

journal_title：Scandinavian journal of immunology

authors： Matre R

更新日期：1976-01-01 00:00:00

abstract：:The role of several adhesion molecules for lymphocyte-endothelial interactions in the synovia of rheumatoid arthritis patients was studied using the frozen section assay. Partial inhibition of lymphocyte binding to endothelium of synovial sections could be observed with antibodies against CD44, L-selectin, and beta 1-...

journal_title：Scandinavian journal of immunology

authors： Fischer C,Thiele HG,Hamann A

更新日期：1993-08-01 00:00:00

abstract：:Flow cytometric analysis of splenocytes from mice infected with lymphocytic choriomeningitis virus revealed marked and long-standing up-regulation of LFA-1 expression on CD8+, but not on CD4+ T cells. Appearance of CD8+ T cells with a changed expression of adhesion molecules reflected polyclonal activation and expansi...

journal_title：Scandinavian journal of immunology

authors： Andersson EC,Christensen JP,Scheynius A,Marker O,Thomsen AR

更新日期：1995-07-01 00:00:00

abstract：:Spleen cells or thymocytes immune to one H-2 genotype are cytotoxic to allogeneic target cells of a third-party genotype, provided the target shares private specificities determined by either the H-2K or the H-2D locus of the H-2 complex with the H-2 genotype used for sensitization in vivo. The present results on elim...

journal_title：Scandinavian journal of immunology

authors： Jorgensen PN,Güttler F,Rubin B

更新日期：1975-01-01 00:00:00

abstract：:This study describes Leishmania antigen-induced activation of lymphocytes isolated from Kenyan donors, previously treated for visceral leishmaniasis, and from Danish and Kenyan controls. Peripheral blood mononuclear cells (PBMC) from cured Kala-Azar patients proliferated and produced Interferon-gamma in vitro in respo...

journal_title：Scandinavian journal of immunology

authors： Kemp M,Theander TG,Handman E,Hey AS,Kurtzhals JA,Hviid L,Sørensen AL,Were JO,Koech DK,Kharazmi A

更新日期：1991-02-01 00:00:00

abstract：:We investigated dietary antigen-specific T-cell responses in mesenteric lymph nodes (MLN) and Peyer's patches (PP) in noncolitic control mice as well as in colitis-prone mice prior to onset of histological active colitis. T cells were restimulated in vitro with constituents isolated from the mouse diet. Interestingly,...

journal_title：Scandinavian journal of immunology

authors： Bjursten M,Hultgren Hörnquist E

更新日期：2005-01-01 00:00:00

abstract：:Alterations in duodenal Ig-producing cells induced by two oral cholera vaccinations were studied by two-colour immunofluorescence in mucosal tissue sections from adults with selective IgA deficiency (IgAD), either with (n = 7) or without (n = 9) frequent infections, infection-prone patients with combined IgAD and IgG ...

journal_title：Scandinavian journal of immunology

authors： Nilssen DE,Friman V,Theman K,Björkander J,Kilander A,Holmgren J,Hanson LA,Brandtzaeg P

更新日期：1993-08-01 00:00:00