In active chronic rheumatoid arthritis, dipeptidyl peptidase IV density is increased on monocytes and CD4(+) T lymphocytes.

abstract：:In vitro lymphocyte stimulation was performed on peripheral blood lymphocytes from 48 leprosy patients, 15 healthy contacts of leprosy patients, and 16 normal controls who lived in a leprosy-free area and who had not been exposed to leprosy. Tuberculin PPD and an antigen fraction. MLW 1, prepared from M. leprae, were ...

journal_title：Scandinavian journal of immunology

authors： Closs O,Reitan LJ,Negassi K,Harboe M,Belehu A

更新日期：1982-08-01 00:00:00

abstract：:Two monoclonal antibodies (MoAbs), F10.2 and F10.3, were selected for their ability to interfere in homotypic adhesion of human B cells. Precipitation studies and binding to intercellular adhesion molecule 1 (ICAM-1, CD54) cDNA transfected COS cells revealed that both MoAbs are directed against ICAM-1. The binding of ...

journal_title：Scandinavian journal of immunology

authors： Bloemen P,Moldenhauer G,van Dijk M,Schuurman HJ,Bloem AC

更新日期：1992-05-01 00:00:00

abstract：:A clear correlation was observed between the presence of an Ia-like antigenic B-cell system Ly-Li, detected serologically, and three cellular immunological techniques: [1] mixed lymphocyte reaction (MLR) inhibition by an anti-Li antiserum; [2] level of restimulation of anti-Ly-Li in-vitro-primed lymphocytes; and [3] d...

journal_title：Scandinavian journal of immunology

authors： Sasportes M,Mawas C,Crosier P,Charmot D,Legrand L,Dausset J

更新日期：1977-01-01 00:00:00

abstract：:The lectin pathway (LP) of the complement system may initiate inflammatory reactions when body tissue is altered. We aimed to investigate levels of the LP proteins in out-of-hospital cardiac arrest patients, and to compare these with healthy individuals. Furthermore, we aimed to clarify whether duration of targeted te...

journal_title：Scandinavian journal of immunology

authors： Haugaard SF,Jeppesen AN,Troldborg A,Kirkegaard H,Thiel S,Hvas AM

更新日期：2018-06-09 00:00:00

abstract：:Spleen cells from C3H/HeJ mice fail to develop both proliferative responses and increased polyclonal antibody secretion in the presence of concentrations of the B-cell mitogen lipopolysaccharide that are optimal for the induction of B-cell responses in conventional strains. This unresponsiveness is selective for lipop...

journal_title：Scandinavian journal of immunology

authors： Coutinho A,Gronowicz E,Sultzer BM

更新日期：1975-01-01 00:00:00

abstract：:(C3H/TifxDBA/2)F1 mice, immunized with viable BALB/c plasmacytoma MOPC315 cells, produce antibodies directed against a cell-surface antigen. The strain and tissue distribution of this antigen was identical to that of the plasma cell differentiation alloantigen PC.1. The antigen is absent in the mouse strain C3H/Tif bu...

journal_title：Scandinavian journal of immunology

authors： Gaudernack G,Hannestad K

更新日期：1979-01-01 00:00:00

abstract：:An idiotypic network model of AIDS pathogenesis is described in which the T cell receptor plays a role both in infection and as a target of autoimmunity. This is an extension of a previously published autoimmunity model, and provides explanations for several otherwise puzzling aspects of AIDS pathogenesis. In the mode...

journal_title：Scandinavian journal of immunology

authors： Hoffmann GW

更新日期：1995-04-01 00:00:00

abstract：:To compare the receptor patterns for mitogenic and non-mitogenic substances, surface glycoproteins of human lymphocytes were labelled with the lactoperioxidase-catalysed iodination technique and with a galactose oxidase-tritiated sodium borohydride technique. Labelled cells were detergent-solubilized, and the lysates ...

journal_title：Scandinavian journal of immunology

authors： Skoog VT,Nilsson SF,Weber TH

更新日期：1980-01-01 00:00:00

abstract：:In a previous report the authors demonstrated that acute graft-versus-host disease (GVHD) was associated with pathologic amounts of tumour necrosis factor alpha (TNF-alpha) and the appearance of lipopolysaccharide (LPS) in the blood of GVH reactive mice just prior to death. In this study the authors have investigated ...

journal_title：Scandinavian journal of immunology

authors： Price KS,Nestel FP,Lapp WS

更新日期：1997-03-01 00:00:00

abstract：:Analysis of seven variable-diversity-joining (VDJ) gene rearrangements in B splenocytes from a 125-day-old bovine foetus revealed an extensive heavy-chain complementarity-determining region 3 (CDR3H) length variation (9-56 codons). Indeed, the global CDR3H size spectratyping of foetal VDJ rearrangements substantiated ...

journal_title：Scandinavian journal of immunology

authors： Saini SS,Kaushik A

更新日期：2002-02-01 00:00:00

abstract：:The migration inhibition in vitro induced by measles virus material on leukocytes from 17 patients with multiple sclerosis (MS) was compared with that of 8 patients with various other central nervous system diseases and that of 12 healthy blood donors. Significant differences could not be demonstrated. The results do ...

journal_title：Scandinavian journal of immunology

authors： Nordal HJ,Froland SS,Vandvik B,Norrby E

更新日期：1976-01-01 00:00:00

abstract：:Multifactorial involvement in the pathogenesis of autoimmune NZB/W F1 mice has been well documented. To further elucidate the role of cytokines in the disease development of murine lupus, single spleen cells isolated from NZB/W F1 and non-autoimmune C57BL/6 mice were stimulated with T cell mitogens or anti-CD3 antibod...

journal_title：Scandinavian journal of immunology

authors： Lin LC,Chen YC,Chou CC,Hsieh KH,Chiang BL

更新日期：1995-10-01 00:00:00

abstract：:Peripheral blood mononuclear cells from a donor with a high titre of anti-hepatitis B surface (HBs) antibodies were fused with a cell line that was positive for Epstein-Barr virus nuclear antigen and sensitive to hypoxanthine-aminopterine-thymidine. A cell line was established that produces a monoclonal IgG1 lambda an...

journal_title：Scandinavian journal of immunology

authors： Stricker EA,Tiebout RF,Lelie PN,Zeijlemaker WP

更新日期：1985-09-01 00:00:00

abstract：:An immunization protocol that induces antibodies (Abs) directed to cryptic epitopes of a protein antigen (Ag) reduces the efficacy of vaccines that ideally should induce Abs against native epitopes. We have shown earlier that viral infections concomitant with immunization against a protein tend to shift the Ab specifi...

journal_title：Scandinavian journal of immunology

authors： Gómez KA,Longhi SA,Marino VJ,Mathieu PA,Loureiro ME,Coutelier JP,Roguin LP,Retegui LA

更新日期：2003-02-01 00:00:00

abstract：:The complement system is regarded as an important component of the innate defence system against invading bacteria. However, synergistic actions between the complement and the other components of innate immunity are incompletely known. Human group IIA phospholipase A(2) (hGIIA PLA(2)) is an effective antibacterial enz...

journal_title：Scandinavian journal of immunology

authors： Grönroos JO,Salonen JH,Viander M,Nevalainen TJ,Laine VJ

更新日期：2005-10-01 00:00:00

abstract：:Extracts of the leaves and roots from the tree Artocarpus tonkinensis A Cheval (family Moraceae) are used in traditional Vietnamese medicine in order to treat backache as well as rheumatic joint diseases. We prepared an ethyl acetate (EtOAc) extract from this plant and tested its anti-inflammatory properties in an exp...

journal_title：Scandinavian journal of immunology

authors： Ngoc DD,Catrina AI,Lundberg K,Harris HE,Ha NT,Anh PT,Larsson P

更新日期：2005-03-01 00:00:00

abstract：:Tumour-draining lymph node T cells are an excellent source of effector T cells that can be used in adoptive tumour immunotherapy because they have already been sensitized to tumour-associated antigens in vivo. However, such tumour-specific immune cells are not readily obtained from the host due to poor immunogenicity ...

journal_title：Scandinavian journal of immunology

authors： Ishida A,Tanaka H,Hiura T,Miura S,Watanabe S,Matsuyama K,Kuriyama H,Tanaka J,Kagamu H,Gejyo F,Yoshizawa H

更新日期：2007-11-01 00:00:00

abstract：:There still exist many unanswered questions whether physical exercise is beneficial or harmful to the immune system. The 'open-window' post-exercise hypothesis states that athletes are more susceptible to infections after exercise, but there is a need for further elucidation. The aim of the present study was to invest...

journal_title：Scandinavian journal of immunology

authors： Nielsen HG,Lyberg T

更新日期：2004-10-01 00:00:00

abstract：:Cells produced in murine T-cell colonies grown in methylcellulose have been studied to evaluate their proliferation, phenotypic differentiation, and ability to give rise to cytotoxic cells. Colony-forming cells from presumably cortical or medullary thymocytes, separated by peanut agglutination, or from lymph nodes, sh...

journal_title：Scandinavian journal of immunology

authors： Röpke C,Claësson MH

更新日期：1986-02-01 00:00:00

abstract：:The role of HLA class I subunits in class II-restricted immune responses was investigated by means of a panel of monoclonal antibodies (MoAb) recognizing HLA-A,B,C heavy chain and different beta 2 microglobulin (beta 2m) epitopes. MoAb against either class I subunit strongly inhibited mixed lymphocyte cultures, genera...

journal_title：Scandinavian journal of immunology

authors： Spagnoli GC,Ausiello CM,Cassone A,Casciani CU,Bellone G,Malavasi F

更新日期：1987-06-01 00:00:00

abstract：:We have examined for the presence or absence of T cell receptor V-alpha (VA) and V-beta (VB) gene expression in infiltrating T lymphocytes (ITL) isolated from Graves' thyroid glands in comparison to paired peripheral blood lymphocyte (PBL) samples using a qualitative based polymerase chain reaction (PCR) assay. Sequen...

journal_title：Scandinavian journal of immunology

authors： Caso-Peláez E,McGregor AM,Banga JP

更新日期：1995-02-01 00:00:00

abstract：:Intradermal inoculation of mice with naked plasmid DNA encoding the regulatory HIV-1 Nef protein was shown to induce Nef-specific T and B cell responses. Co-inoculation with an expression vector encoding murine granulocyte-macrophage colony-stimulating factor (GM-CSF), a cytokine known to facilitate the induction of p...

journal_title：Scandinavian journal of immunology

authors： Svanholm C,Löwenadler B,Wigzell H

更新日期：1997-09-01 00:00:00

abstract：:Pneumocystis carinii is an opportunistic pathogen that causes pneumonia in immunocompromised hosts. In the normal host, P. carinii is susceptible to an array of first line host defense mechanisms that are operative in the lung. Alveolar macrophages play a central role in the clearance of inhaled organisms. The macroph...

journal_title：Scandinavian journal of immunology

authors： Stehle SE,Rogers RA,Harmsen AG,Ezekowitz RA

更新日期：2000-08-01 00:00:00

abstract：:Administration of D-penicillamine (50 mg/kg/day orally) to rats with adjuvant arthritis for up to 42 days significantly modified the incorporation of 3H-thymidine (3H-TdR) in concanavalin A (Con A)-stimulated lymph node cells. Treatment with D-penicillamine abolished the ability of macrophages from arthritic rats to i...

journal_title：Scandinavian journal of immunology

authors： Binderup L,Bramm E,Arrigoni-Martelli E

更新日期：1980-01-01 00:00:00

abstract：:Based on CD14 and CD16 expression, human peripheral blood monocytes (MO) can be divided into a major CD14(high) CD16(-) population and two minor CD14(high) CD16(+) and CD14(dim) CD16(+) subpopulations. CD14(dim) CD16(+) MO are well characterized and regarded as pro-inflammatory because upon stimulation produce TNF-alp...

journal_title：Scandinavian journal of immunology

authors： Skrzeczyńska-Moncznik J,Bzowska M,Loseke S,Grage-Griebenow E,Zembala M,Pryjma J

更新日期：2008-02-01 00:00:00

abstract：:In a group of 20 patients with asymptomatic paraproteinemia, as judged after at least 3 years of follow-up, the primary and secondary antibody response to Helix pomatia hemocyanin (HPH) was defective as compared with the response in controls. The class of antibody was assessed by mercaptoethanol (ME) treatment of seru...

journal_title：Scandinavian journal of immunology

authors： Weits J,de Gast GC,The TH,Marrink J,Mandema E

更新日期：1976-01-01 00:00:00

abstract：:Non-specific antibody production usually accompanies the T-cell-regulated B-cell response. In this paper the mechanisms involved in non-MHC-restricted T-B-cell interaction were studied. As previously shown for NK cells, activated B cells induce IFN-gamma and TNF alpha production in non-MHC-restricted cytotoxic T lymph...

journal_title：Scandinavian journal of immunology

authors： Becker JC,Dummer R,Von Wussow P,Burg G,Schmidt RE

更新日期：1992-08-01 00:00:00

abstract：:The immune system produces specific antibodies (Ab) against any antigens (Ag) of exogenous and endogenous origins with a diverse repertoire of V-region specificities. The primary V-region repertoire is created by the rearrangement of immunoglobulin (Ig) V-region, D- and J-segments with the insertion of N- and P-sequen...

journal_title：Scandinavian journal of immunology

authors： Sakaguchi N,Maeda K,Kuwahara K

更新日期：2011-06-01 00:00:00

abstract：:Human peripheral blood lymphocytes (PBL) were activated with K46M, a m mitogenic monoclonal antibody against La-reactive T lymphocyte surface structures. The cultures were expanded in the presence of interleukin 2 (IL-2). After 1 month of culture, the activated T cells were cloned by limiting dilution at 0.5 cells/wel...

journal_title：Scandinavian journal of immunology

authors： Berzins T,Vargas-Cortes M,Axelsson B,Hammarström ML,Hammarström S,Perlmann P

更新日期：1988-11-01 00:00:00

abstract：:Inflammatory DCM (iDCM) may be related to autoimmune processes. An immunoadsorption (IA) has been reported to improve cardiac hemodynamics. The benefit of IA is probably related to the removal of autoantibodies. A recent study suggests additional effects of IA on the T cell-mediated immune reactions, especially on reg...

journal_title：Scandinavian journal of immunology

authors： Bulut D,Creutzenberg G,Mügge A

更新日期：2013-01-01 00:00:00