Role of HLA class II products in proliferative T-lymphocyte responses to PPD. Evidence of a regulatory influence associated with MB1.

abstract：:In the present study, T-cell subsets from aged individuals were examined by using anti-BAT (brain-associated thymocyte antigen) serum. Anti-BAT serum was raised against the human fetal brain at 28 weeks of gestation. After absorption wit AB erythrocytes, B-cell lines, and leukaemic cells, anti-BAT serum was T cell-spe...

journal_title：Scandinavian journal of immunology

authors： Abe T,Morimoto C,Toguchi T,Kiyotaki M,Homma M

更新日期：1981-01-01 00:00:00

abstract：:Beta 2-glycoprotein I (beta 2-GPI) is a 50 kDa protein in human plasma composed of five repeating complement control protein modules thereby closely resembling complement factor H which has 20 such units. Both beta 2-GPI and factor H (150 kDa) have binding sites for negatively charged polyions. beta 2-GPI has been sho...

journal_title：Scandinavian journal of immunology

authors： Puurunen M,Jokiranta S,Vaarala O,Meri S

更新日期：1995-11-01 00:00:00

abstract：:The autologous mixed lymphocyte reaction (AMLR) and T-cell subsets defined with monoclonal antibodies were examined in the peripheral blood of six patients with chronic mucocutaneous candidiasis (CMC). The AMLR was deficient in four of six patients when compared with simultaneously studied healthy controls. These pati...

journal_title：Scandinavian journal of immunology

authors： Gupta S

更新日期：1985-06-01 00:00:00

abstract：:Cellular immune response and delayed-type hypersensitivity reactions are considered to play a major role in the immunopathogenesis of pulmonary tuberculosis (PTB). But the exact mechanism is still to be clarified. Th1 cells are mainly involved in cellular immune responses in PTB and provide a normal healing process wi...

journal_title：Scandinavian journal of immunology

authors： Aktas E,Ciftci F,Bilgic S,Sezer O,Bozkanat E,Deniz O,Citici U,Deniz G

更新日期：2009-09-01 00:00:00

abstract：:Foot-and-mouth disease (FMD) caused by FMD virus (FMDV) is a major health and economic problem in the farming industry. Vaccination of livestock against this highly infectious viral disease is crucial, and inactivated FMD vaccine has been effective at controlling infection. However, accumulated data show that the inac...

journal_title：Scandinavian journal of immunology

authors： Kang J,Zuo Y,Guo Q,Wang H,Liu Q,Liu Q,Xia G,Kang Y

更新日期：2015-11-01 00:00:00

abstract：:The epidermis has been identified as an important site for the initiation of immunological events. In addition to the macrophage-like Langerhans cells, keratinocytes within the epidermal cells have been shown to act as immunoregulatory cells through the secretion of cytokines such as epidermal cell-derived thymocyte-a...

journal_title：Scandinavian journal of immunology

authors： Luger TA,Köck A,Danner M

更新日期：1985-05-01 00:00:00

abstract：:Discontinuous Percoll gradients have been used to obtain selected human peripheral blood T lymphocytes without having to resort to interactions with immune complexes in the fractionation of Tm, Tg and Ta cells. Here, we could show that Ta cells represent a heterogeneous population with no distinct density profile, in ...

journal_title：Scandinavian journal of immunology

authors： Canonica GW,Kabelitz D,Sjöberg O,Aigrain Y,Wigzell H

更新日期：1982-09-01 00:00:00

abstract：:To evaluate the role of IFN-gamma (interferon gamma) in IL-12- (interleukin-12)-induced inhibition of the inflammatory response in the eye during endotoxin-induced uveitis (EIU). C57BL/6 wild type mice and IFN-gamma-deficient (GKO) mice were injected with 250 microg of Salmonella typhymurium endotoxin as a model for E...

journal_title：Scandinavian journal of immunology

authors： Figueiredo F,Commodaro AG,de Camargo MM,Rizzo LV,Belfort R Jr

更新日期：2007-08-01 00:00:00

abstract：:Human mast cell carboxypeptidase (hMC-CP) is a unique product of mast cells. Unlike tryptase and chymase, its potential function and expression in diseased conditions remain largely unknown. To develop an assay for hMC-CP, the recombinant fusion protein of hMC-CP and purified native skin hMC-CP was prepared, and two n...

journal_title：Scandinavian journal of immunology

authors： Zhou Y,Chen Z,He S

更新日期：2006-11-01 00:00:00

abstract：:Thymopentin (TP-5) is a synthetic pentapeptide that corresponds to the active 32-36 amino acid sequence of the thymic hormone thymopoietin, of which it retains all the immunomodulatory properties. In this study, we have evaluated the effects of long term prophylactic treatment with TP-5 on the clinical, immunological ...

journal_title：Scandinavian journal of immunology

authors： Nicoletti F,Zaccone P,Magro G,Barcellini W,Cavallaro V,Belli G,Cocuzza C,di Marco R,Meroni PL

更新日期：1994-11-01 00:00:00

abstract：:The predominant selection of CRI-A-bearing antibodies during the anti-arsonate (ARS) response of A/J mice has been used as a model to analyse the mechanism involved in the process of clonal selection and establishment of predominance. In order to assess the importance of the affinity and adaptability of CRI-A clones i...

journal_title：Scandinavian journal of immunology

authors： Gaya A,Alsinet E,Freixas M,Vives J

更新日期：1988-09-01 00:00:00

abstract：:Chronic hepatitis B virus (HBV) infection affects millions of people worldwide and about half a million people die every year. India represents the second largest pool of chronic HBV infections with an estimated 40 million chronically infected patients. Persistence or clearance of HBV infection mainly depends upon hos...

journal_title：Scandinavian journal of immunology

authors： Vyas AK,Jindal A,Hissar S,Ramakrishna G,Trehanpati N

更新日期：2017-07-01 00:00:00

abstract：:Sixteen plasma proteins were studied in the supernatants from 20 successive washings of human leucocytes by a new sensitive immunoelectrophoretic method. In the first few supernatants a fast and parallel decrease in concentration of all proteins took place, but for 11 proteins this was followed by a phase of slow decr...

journal_title：Scandinavian journal of immunology

authors： Andersen MM

更新日期：1982-04-01 00:00:00

abstract：:We have studied the interaction of mitogenic lectins such as phytohaemagglutinin (PHA) and concanavalin A (Con A) with both surface molecules which, by the use of monoclonal antibodies, are known to trigger T-cell mitogenesis. Monoclonal antibodies recognizing the T-lymphocyte receptor for antigen (Ti) and/or its asso...

journal_title：Scandinavian journal of immunology

authors： Leca G,Boumsell L,Fabbi M,Reinherz EL,Kanellopoulos JM

更新日期：1986-05-01 00:00:00

abstract：:Cellular immune responses to recombinant (r) Sm14 were examined in chronic, treated patients and uninfected individuals living in an endemic area for schistosomiasis. The lymphocyte proliferative responses and cytokine profile to this antigen were evaluated. Peripheral blood mononuclear cells (PBMC) of all groups stud...

journal_title：Scandinavian journal of immunology

authors： Brito CF,Caldas IR,Coura Filho P,Correa-Oliveira R,Oliveira SC

更新日期：2000-06-01 00:00:00

abstract：:The J-chain content of 3 IgM and 24 IgA preparations was quantitated by an immunochemical technique after reduction with 20mM dithiothreitol. The amounts released ranged from undetectable (less than 0.1 mg) to 7.3 mg per 100 mg of Ig. Most of the J-chain-deficient proteins were monomeric, but four polymeric IgA prepar...

journal_title：Scandinavian journal of immunology

authors： Brandtzaeg P

更新日期：1976-01-01 00:00:00

abstract：:This study was designed to determine seasonal changes in cytokines, soluble CD23 and specific IgE in the serum of patients with seasonal allergic rhinitis, and the effect of immunotherapy on these seasonal changes. Fifty-four patients with seasonal allergic rhinitis caused by Japanese ceder pollens were divided into a...

journal_title：Scandinavian journal of immunology

authors： Ohashi Y,Nakai Y,Kakinoki Y,Ohno Y,Tanaka A,Masamoto T,Sakamoto H,Washio Y,Kato A

更新日期：1997-07-01 00:00:00

abstract：:Amyloid was extracted from the liver of a horse that had developed amyloidosis after being used for several years for the production of antibodies to bacterial antigens. The amyloid fibrils were shown to be of the AA type. Two AA proteins with molecular weights of 9000 and 11,000 and with identical partial N-terminal ...

journal_title：Scandinavian journal of immunology

authors： Husebekk A,Husby G,Sletten K,Marhaug G,Nordstoga K

更新日期：1986-06-01 00:00:00

abstract：:The T-cell repertoire is shaped by the positive and negative selection of immature CD4(+) CD8(+) double positive (DP) thymocytes. Positive selection of DP T cells to the CD4(+) CD8(-) and CD4(-) CD8(+) simple positive (SP) lineages is a multistep process which involves cellular interactions between thymocytes and stro...

journal_title：Scandinavian journal of immunology

authors： Nepomnaschy I,Lombardi G,Bekinschtein P,Berguer P,Francisco V,de Almeida J,Buggiano V,Pasqualini CD,Piazzon I

更新日期：2000-12-01 00:00:00

abstract：:Sjögren's syndrome is characterized by dryness of the eyes and the mouth due to mononuclear cell infiltration of the lacrimal and salivary glands. The aetiology is unknown but autoimmunity is considered to play a significant role in the pathogenesis. Recent studies have focused on the fact that tear and salivary flow ...

journal_title：Scandinavian journal of immunology

authors： Humphreys-Beher MG,Brayer J,Yamachika S,Peck AB,Jonsson R

更新日期：1999-01-01 00:00:00

abstract：:Human peripheral blood monocyte subsets with and without Fc receptor for human IgG are known to suppress (FcR+) and enhance (FcR-) pokeweed mitogen-induced polyclonal immunoglobulin synthesis in vitro. The ability of these subsets to modulate immunoglobulin production in the presence or absence of OKT8+ T cells and un...

journal_title：Scandinavian journal of immunology

authors： Pryjma J,Flad HD,Gruber M,Ernst M

更新日期：1986-07-01 00:00:00

abstract：:Mitogen-induced cell-mediated cytotoxicity (MICC) of human peripheral blood granulocytes (PMN) and lymphocytes (PBL) was studied by using chicken erythrocytes as targets. The possible mechanisms were elicited bidirectionally by means of the MICC inhibition test and by functional analysis of lectin. In our preliminary ...

journal_title：Scandinavian journal of immunology

authors： Yue CL,Tanimoto K,Horiuchi Y

更新日期：1981-10-01 00:00:00

abstract：:We have previously shown that various benign and malignant natural killer (NK)-resistant monolayer cells inhibit endogenous human NK activity, probably by reducing the secretion of cytotoxic factors from the effector cells. The nature of the molecules responsible for the inhibition has been unclear. In this study we s...

journal_title：Scandinavian journal of immunology

authors： Heiskala MK,Stenman UH,Koivunen E,Carpén O,Saksela E,Timonen T

更新日期：1988-07-01 00:00:00

abstract：:Modified C-reactive protein (mCRP) has been reported to non-specifically bind to immunoglobulins; notwithstanding, the nature of these interactions is not clear. The aim of this study was to investigate the binding of antibodies directed against HSA and IgG to mCRP, fibrinogen (Fg), IgG, fibronectin (Fn) and C1q and i...

journal_title：Scandinavian journal of immunology

authors： Boncler M,Dudzińska D,Nowak J,Watała C

更新日期：2012-07-01 00:00:00

abstract：:With the aim of producing large quantities of mRNA-transfected monocyte-derived dendritic cells (DCs) to be used as cancer vaccines, a new clinical grade procedure has been developed. Peripheral blood mononuclear cells (PBMCs) obtained by leukapheresis were enriched for monocytes by immunomagnetic depletion of CD19+ B...

journal_title：Scandinavian journal of immunology

authors： Mu LJ,Gaudernack G,Saebøe-Larssen S,Hammerstad H,Tierens A,Kvalheim G

更新日期：2003-11-01 00:00:00

abstract：:The CD4 molecule is an important cell surface molecule expressed on many cell types including T-helper cells. CD4 can be shed from cells, and the truncated soluble form of CD4 (sCD4) has been found elevated in serum in several diseases. In this study the authors show that migration of polymorphonuclear neutrophils (PM...

journal_title：Scandinavian journal of immunology

authors： Goto H,Gidlund M

更新日期：1996-06-01 00:00:00

abstract：:Human endothelial cells (EC), cultured serum-free, synthesize de novo protein which increasingly bind to agarose beads (an alternative pathway activator), until a plateau phase is reached after 24-48 h. EC synthesize functional C3, C5, C6, C8 and C9, which were detected on co-cultured agarose beads, using relevant pol...

journal_title：Scandinavian journal of immunology

authors： Johnson E,Hetland G

更新日期：1991-06-01 00:00:00

abstract：:Calf spleen extractive injection (CSEI), extracted from the spleen of healthy cows (within 24 h of birth), is a small peptides enriched extraction while the ratio between peptide and ribose is 76 ± 15.2 mg/μg. CSEI is usually used as an ancillary agent to assist cancer patients with immune dysfunction. The present stu...

journal_title：Scandinavian journal of immunology

authors： Jia D,Lu W,Wang C,Sun S,Cai G,Li Y,Wang G,Liu Y,Zhang M,Wang D

更新日期：2016-07-01 00:00:00

abstract：:T lymphocytes are activated by the interaction between the T-cell antigen receptor (TCR) and peptides presented by major histocompatibility complex (MHC) molecules. The avidity of this TCR-pMHC interaction is very low. Therefore, several hypotheses have been put forward to explain how T cells become specifically activ...

journal_title：Scandinavian journal of immunology

authors： Rubin B,Knibiehler M,Gairin JE

更新日期：2007-08-01 00:00:00

abstract：:The aim of this study was to investigate the epitope recognition pattern of La(SS-B) autoantibodies in sera from patients with Sjögren's syndrome (SS) and systemic lupus erythematosus (SLE) using overlapping synthetic decapeptides on solid phase. Eighty different decapeptides with five amino acids overlap from the hum...

journal_title：Scandinavian journal of immunology

authors： Haaheim LR,Halse AK,Kvakestad R,Stern B,Normann O,Jonsson R

更新日期：1996-01-01 00:00:00