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A proliferation of pathogens through the 20th century.

Abstract：

:A substantial proportion of immunologists, microbiologists and health professionals--and, indeed, many dictionaries--currently regard the term pathogen as a synonym for a pathogenic organism (most often a micro-organism). I will argue that this is a distortion of its original meaning--'a specific causative agent of disease'. An analysis of the historical use of the term pathogen together with a comparison of the meanings of pathogen, pathogenic and pathogenesis suggest that this was an insidious change. It began as a convenient abbreviation, escalated into a misappropriation and is now lodged in bio-medicine's popular lexicon. In science, we should resist the pressures brought about by the mass action of common usage--unless there is a good, logical reason to accept this change. I propose that this common usage results in a distortion and leads to conceptual confusion, particularly when we try to understand the interaction between hosts and invasive organisms. This drift, in which pathogen becomes exclusively a living organism, is corrupting. There is a strong case for correcting and reversing it.

journal_name

Scand J Immunol

journal_title

Scandinavian journal of immunology

authors

Cunliffe J

doi

10.1111/j.1365-3083.2008.02130.x

subject

Has Abstract

pub_date

2008-08-01 00:00:00

pages

120-8

issue

2

eissn

0300-9475

issn

1365-3083

pii

SJI2130

journal_volume

68

pub_type

历史文章,杂志文章

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