A low serum concentration of mannan-binding protein is not associated with serogroup B or C meningococcal disease.

abstract：:Various surface molecules are expressed by activated T cells. Among them, the CD30 antigen has been proposed as a reproducible marker that identifies a subset of differentiated and/or activated T lymphocytes that produce T helper (Th)-2-type cytokines, i.e. interleukin (IL)-4 and IL-5. However, because CD30 has mainly...

journal_title：Scandinavian journal of immunology

authors： Spinozzi F,Agea E,Piattoni S,Falini B,Grignani F,Bertotto A

更新日期：1997-04-01 00:00:00

abstract：:The relationship between the so-called natural interferon-alpha (IFN-alpha) producing cell (IPC), stimulated to produce IFN-alpha by herpes simplex virus type 1 (HSV), and of dendritic cells (DC) in peripheral blood leucocytes was investigated. The simultaneous expression of cell surface antigens and intracellular IFN...

journal_title：Scandinavian journal of immunology

authors： Svensson H,Johannisson A,Nikkilä T,Alm GV,Cederblad B

更新日期：1996-08-01 00:00:00

abstract：:Infection with murine gammaherpesvirus 68 has become an accepted model for studying the virus/host interactions with regard to gammaherpesvirus infections. Previous studies using gene-deficient mice have revealed that neither IFNγ nor perforin is essential in controlling the outcome of infection or the virus load duri...

journal_title：Scandinavian journal of immunology

authors： Bartholdy C,Høgh-Petersen M,Storm P,Holst PJ,Orskov C,Christensen JP,Thomsen AR

更新日期：2014-06-01 00:00:00

abstract：:The immune response of adult BALB/c mice against the bacterial antigen dextran B1355S (Dex) is well characterized as thymus independent (TI type 2) and Igha linked. The antisera consist of mainly IgM/lambda antibodies directed against the alpha(1-->3) glucosidic linkage. This study describes the immune response agains...

journal_title：Scandinavian journal of immunology

authors： Willers J,Weiler E,Kolb C

更新日期：1995-09-01 00:00:00

abstract：:This study (1) analysed the percentage of γδ T cells, γδ T cell subsets, Th17 cells and regulatory T cells (Treg cells) and (2) determined the role of IL-23 in primary nephrotic syndrome (PNS) patients with active disease and in remission. Eighty-four patients with PNS and 51 healthy age-matched controls were included...

journal_title：Scandinavian journal of immunology

authors： Zhang L,Yan J,Yang B,Zhang G,Wang M,Dong S,Liu W,Yang H,Li Q

更新日期：2018-01-01 00:00:00

abstract：:Ficolin-2 (L-ficolin), derived from the FCN2 gene, is an innate immunity pattern recognition molecule found in human serum in which inter-individual variation in serum appears to be under genetic control. To validate and extend this finding, we developed a sandwich ELISA for detection of human Ficolin-2 in serum sampl...

journal_title：Scandinavian journal of immunology

authors： Munthe-Fog L,Hummelshøj T,Hansen BE,Koch C,Madsen HO,Skjødt K,Garred P

更新日期：2007-04-01 00:00:00

abstract：:Transgenic techniques in inbred mouse strains are powerful tools to investigate the specific roles of genes in biological pathways and disease models. However, there is increasing concern over the influence of a variable genetic background in such experiments. To date there have been few investigations of the immunolo...

journal_title：Scandinavian journal of immunology

authors： Johansson AC,Vestberg M,Holmdahl R

更新日期：2000-07-01 00:00:00

abstract：:T cells from immune guinea-pigs produce clusters in vitro with macrophages pulsed with soluble protein antigens. The formation of clusters is antigen-specific. Time-lapse cinephotomicrography was used to study the sequence of events leading to cluster formation and the kinetics of already formed clusters. The central ...

journal_title：Scandinavian journal of immunology

authors： Petri J,Braendstrup O,Werdelin O

更新日期：1979-01-01 00:00:00

abstract：:In the present study we describe the production and characterization of a panel of monoclonal antibodies (MoAbs) directed against cruzipain (Crz), the major cysteine proteinase from Trypanosoma cruzi. The five MoAbs, BD6, BF2, CG2, CH8, and DC10 were analysed with respect to affinity and specificity. None of the MoAbs...

journal_title：Scandinavian journal of immunology

authors： Gonzalez G,Orn A,Cazzulo JJ,Grönvik KO

更新日期：1994-10-01 00:00:00

abstract：:The monoclonal antibodies A and B specific for the HN molecule of Sendai virus were used to induce polyclonal and monoclonal anti-idiotypic antibodies. No response was observed in allogeneic Lewis rats, low responses in syngeneic LOU rats, and high responses in allogeneic BN rats and xenogeneic Balb/c mice. The monocl...

journal_title：Scandinavian journal of immunology

authors： Fenner M,Siegmann K,Binz H

更新日期：1986-09-01 00:00:00

abstract：:Hypomorphic mutations in the gene encoding Bruton tyrosine kinase (BTK) may result in milder phenotypes and delayed diagnosis of B-cell related immunodeficiencies due to residual BTK function. Newborn screening for kappa-deleting-recombination-excision circles (KRECs) reliably identifies classical X-linked agammaglobu...

journal_title：Scandinavian journal of immunology

authors： Krüger R,Baumann U,Borte S,Kölsch U,Lorenz MR,Keller B,Harder I,Warnatz K,Ehl S,Schwarz K,Wahn V,von Bernuth H

更新日期：2020-01-01 00:00:00

abstract：:Saliva was collected from 57 infants aged 6 weeks to 2.5 years and the molecular form of IgA was studied by centrifugation on sucrose density gradients. Two distinct populations were identified. Seventy-two per cent of the children had secretory IgA in their salivary secretions, while 28% had a molecular form correspo...

journal_title：Scandinavian journal of immunology

authors： Cripps AW,Gleeson M,Clancy RL

更新日期：1989-03-01 00:00:00

abstract：:Immunoglobulin-secreting cells (ISC) in the peripheral blood of healthy individuals and in the bone marrow, peripheral blood, or plasmacytomas of patients with multiple myeloma were enumerated by a protein-A plaque-forming cell assay after treatment with anti-Ia antibody and complement. Rabbit anti-human B-cell antise...

journal_title：Scandinavian journal of immunology

authors： Nagai K,Nagai T,Takatsuki K,Uchino H

更新日期：1982-06-01 00:00:00

abstract：:Peripheral blood lymphocytes from 43 patients with systemic lupus erythematosus (SLE) and from age- and sex-matched normal controls were cultured with lipopolysaccharide (LPS) to examine the response to the polyclonal B-cell activator. Lymphocytes from active SLE patients incorporated 4840 +/- 471 (mean +/- SE) cpm in...

journal_title：Scandinavian journal of immunology

authors： Abe T,Toguchi T,Takeuchi T,Kiyotaki M,Homma M

更新日期：1981-05-01 00:00:00

abstract：:Antibodies to DNA (anti-DNA) play an important role in the pathogenesis of systemic lupus erythematosus (SLE). In blood, these antibodies may exist in a free, unbound state or as part of complexes with DNA. Furthermore, circulating DNA may be either complexed or free. Because of the central role of these immunoreactan...

journal_title：Scandinavian journal of immunology

authors： Björkman L,Reich CF,Pisetsky DS

更新日期：2003-06-01 00:00:00

abstract：:The specificity of the Fcgamma receptors in normal spleen and liver and in malignant tissues was studied using hemadsorption to cryostat sections. Indicator cells (EA) were sheep erythrocytes (E) sensitized with rabbit IgG antibody (A). The binding of EA to sections of normal and malignant tissues was inhibited by poo...

journal_title：Scandinavian journal of immunology

authors： Matre R

更新日期：1976-01-01 00:00:00

abstract：:The trophoblastic tissue and endothelium of fetal stem vessels in cryostat sections of first-trimester and term human placentae adsorbed erythrocytes sensitized with IgG antibodies of human, rabbit, and guinea pig origin. Native and heat-aggregated human and rabbit IgG, and human IgG subclasses except IgG2 inhibited t...

journal_title：Scandinavian journal of immunology

authors： Matre R

更新日期：1977-01-01 00:00:00

abstract：:Ebola viruses (EBOVs) have been identified as an emerging threat in recent year as it causes severe haemorrhagic fever in human. Epitope-based vaccine design for EBOVs remains a top priority because a mere progress has been made in this regard. Another reason is the lack of antiviral drug and licensed vaccine although...

journal_title：Scandinavian journal of immunology

authors： Khan MA,Hossain MU,Rakib-Uz-Zaman SM,Morshed MN

更新日期：2015-07-01 00:00:00

abstract：:Normal human glomerular basement membrane (H-GBM) was solubilized by collagenase and subjected to crossed immunoelectrophoresis with rabbit antibodies against H-GBM. Seven precipitates appeared with the mobility of alpha, beta, and gamma globulins. Only two of these precipitates might be specific for GBM, since the ot...

journal_title：Scandinavian journal of immunology

authors： Henriksen K,Jensen H

更新日期：1975-01-01 00:00:00

abstract：:Direct contact between lymphokine-activated killer (LAK) cells and tumour cells is believed to be imperative for initiating tumour cell lysis in vitro as well as in vivo. In order to optimize adoptive immunotherapy (AIT) it is therefore desirable to identify the LAK cell subtype, which ensures maximal infiltration of ...

journal_title：Scandinavian journal of immunology

authors： Kjaergaard J,Hokland M,Nannmark U,Hokland P,Basse P

更新日期：1998-06-01 00:00:00

abstract：:The effects of cytoplasmic anti-neutrophil cytoplasm autoantibodies (C-ANCA) and perinuclear ANCA (P-ANCA) immunoglobulin G (IgG) on tissue factor (TF) activity using HL-60 cells in vitro were compared with those of medium, lipopolysaccharide (LPS) and control IgG. Cells were also incubated with both ANCA IgG and cont...

journal_title：Scandinavian journal of immunology

authors： Flores-Suárez LF,Nowack R,Yard BA,Dempfle CE,Van Der Woude FJ

更新日期：2003-01-01 00:00:00

abstract：:Mouse monoclonal antibodies against ED sequence-containing cellular fibronectin (cFn) were used to show that Fn in the inflamed synovium is distinct from the major form of plasma Fn (pFn). An accumulation of cFn was seen at sites of hyperplasia of the rheumatoid synovial membrane and in the walls of small vessels in t...

journal_title：Scandinavian journal of immunology

authors： Walle TK,Vartio T,Helve T,Virtanen I,Kurki P

更新日期：1990-04-01 00:00:00

abstract：:We have studied the effect of interferon in vivo (induced by polyinosinic-polycytidylic acid (pIC] on the natural killer (NK) cell lytic activity and on the numbers of large granular lymphocytes (LGL) and target-binding cells (TBC) in different lymphoid compartments. One day after the pIC induction the spleen containe...

journal_title：Scandinavian journal of immunology

authors： Hurme M,Silvennoinen O,Renkonen R

更新日期：1984-10-01 00:00:00

abstract：:One hundred and twenty IgM-secreting hybridomas derived from unmanipulated 6-day-old BALB/c mice were screened for reactivity with the prototype idiotypic and anti-idiotypic monoclonal antibodies, defining three well established systems, namely TEPC 15:10/13-15, J558:CD3.2, and MOPC 460:F 6(51). Up to 25% of all IgM a...

journal_title：Scandinavian journal of immunology

authors： Araujo PM,Holmberg D,Martinez-A C,Coutinho A

更新日期：1987-05-01 00:00:00

abstract：:Haematopoietic precursors first colonizing the avian embryonic thymus are derived from the intraembryonic sites located around the dorsal aortae. These intraembryonic precursors have previously been demonstrated to include cells that harbour T-cell progenitor capacity and express the Ikaros transcription factor, known...

journal_title：Scandinavian journal of immunology

authors： Liippo J,Koskela K,Lassila O

更新日期：2000-11-01 00:00:00

abstract：:Autoimmune regulator's (AIRE) best characterized role is in the generation immunological tolerance, but it is also involved in many other processes such as spermatogenesis. Loss-of-function mutations in AIRE cause a disease called autoimmune polyendocrinopathy, candidiasis and ectodermal dystrophy (APECED; also called...

journal_title：Scandinavian journal of immunology

authors： Kekäläinen E,Pöntynen N,Meri S,Arstila TP,Jarva H

更新日期：2015-05-01 00:00:00

abstract：:The Kva IgG2(k) myeloma protein showed a complete resistance to papain in the presence of cysteine at neutral pH, and a higher resistance to trypsin and alpha-chymotrypsin digestion than other IgG2 proteins. On the other hand, the Kva molecule was cleaved by pepsin at low pH to give the expected F(ab')2 fragment. When...

journal_title：Scandinavian journal of immunology

authors： Vogt RA,Michaelsen TE

更新日期：1987-07-01 00:00:00

abstract：:HLA class II molecules may be induced on non-lymphoid cells by gamma-interferon (IFN-gamma). We investigated if HLA class II molecules induced by IFN-gamma on the HT29 colonic carcinoma cell line are functional, i.e. if they may be recognized by allogeneic T cells. We found that IFN-gamma-treated HT29 (HT29IFN) cells ...

journal_title：Scandinavian journal of immunology

authors： Lundin KE,Sollid LM,Bosnes V,Gaudernack G,Thorsby E

更新日期：1990-04-01 00:00:00

abstract：:Three strains of mice bearing the autosomal recessive lpr gene (MRL, C57BL/6, and C3H) that had spontaneously developed a lupus-like disease were studied sequentially for functional natural killer (NK) and natural cytotoxic (NC) cell activity. Natural killing was impaired in spleen and bone marrow cells from all the l...

journal_title：Scandinavian journal of immunology

authors： Pan LZ,Dauphinée MJ,Ansar Ahmed S,Talal N

更新日期：1986-04-01 00:00:00

abstract：:Bacterial DNA differs from mammalian DNA by the presence of unmethylated cytosine-phosphate-guanosine (CpG) motifs. The immunostimulatory properties of a DNA vaccine have been suspected to be associated with these motifs. The aim of this study was to assess the inactivation of the immunostimulatory potential of a plas...

journal_title：Scandinavian journal of immunology

authors： Cornélie S,Poulain-Godefroy O,Lund C,Vendeville C,Ban E,Capron M,Riveau G

更新日期：2004-02-01 00:00:00