Abstract:
:We show that N-1 in adenine of chromosomal DNA is methylated by treatment of metaphase chromosomes with dimethylsulphate while this is not the case in chromatin. The data on methylation are consistent with those obtained from the experiments with S1-nuclease treatment of chromatin and chromosomes. This suggests a disarrangement of DNA secondary structure in the metaphase chromosomes.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Belyaev ND,Budker VG,Dubrovskaya VA,Matveeva NMdoi
10.1016/0014-5793(83)80167-7subject
Has Abstractpub_date
1983-04-18 00:00:00pages
285-7issue
2eissn
0014-5793issn
1873-3468pii
0014-5793(83)80167-7journal_volume
154pub_type
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