Abstract:
:Effects of sublethal concentration (0.8 of LC50 96 h) of nickel sulphate (NiSO4 X 7H2O) on muscle glycogen and blood lactic acid levels of a freshwater teleost, Colisa fasciatus, at time intervals from 3-96 h have been recorded. Muscle glycogen levels showed a general decrease at all time intervals compared with controls, with a maximum decrease of 35.2% at 96 h (P less than 0.001). Blood lactic acid showed an increase at all stages attaining a maximum of 78.12% at 12 h (P less than 0.001) except at 24 h where, for reasons not clearly understood, a distinct fall was recorded. The muscle glycogenolysis accompanied by blood hyperlacticaemia is probably the result of some direct action of nickel on the fish. The severe stress conditions caused by nickel-induced pathological changes in the gills and blood may also be responsible for these metabolic changes.
journal_name
Toxicol Lettjournal_title
Toxicology lettersauthors
Chaudhry HSdoi
10.1016/0378-4274(84)90193-0subject
Has Abstractpub_date
1984-01-01 00:00:00pages
115-21issue
1eissn
0378-4274issn
1879-3169pii
0378-4274(84)90193-0journal_volume
20pub_type
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journal_title:Toxicology letters
pub_type: 杂志文章
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journal_title:Toxicology letters
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journal_title:Toxicology letters
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journal_title:Toxicology letters
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journal_title:Toxicology letters
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journal_title:Toxicology letters
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journal_title:Toxicology letters
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journal_title:Toxicology letters
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journal_title:Toxicology letters
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journal_title:Toxicology letters
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journal_title:Toxicology letters
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journal_title:Toxicology letters
pub_type: 杂志文章
doi:10.1016/j.toxlet.2011.04.002
更新日期:2012-08-13 00:00:00
abstract::Exposition to cadmium (Cd) has been linked to bone metabolism alterations and occurrence of osteoporosis. Despite its known renal toxicity which indirectly disrupts bone metabolism through impairment of vitamin D synthesis, increasing evidence argues for the direct action of Cd on bone-forming osteoblasts. Indeed, acc...
journal_title:Toxicology letters
pub_type: 杂志文章
doi:10.1016/j.toxlet.2012.10.006
更新日期:2012-12-17 00:00:00
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journal_title:Toxicology letters
pub_type: 杂志文章
doi:10.1016/j.toxlet.2008.09.002
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journal_title:Toxicology letters
pub_type: 杂志文章
doi:10.1016/j.toxlet.2014.06.843
更新日期:2014-08-17 00:00:00
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journal_title:Toxicology letters
pub_type: 杂志文章
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journal_title:Toxicology letters
pub_type: 杂志文章
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