Abstract:
:The rejection of skin allografts by the larval lamprey, Lampetra reissneri, was studied by light- and electron-microscopy, with particular attention to the cell types involved in the reaction. In all allografts, melanophores were destroyed within 20-60 days (the mean survival time, 36 +/- 12 days). Neither the epidermis nor the underlying collagenous lamella was invaded by host cells until the 60th day. A heavy infiltration of host leucocytes was observed in the allografts in melanophore and adipose layers and in the bundles of muscles. Throughout all stages from 10 to 60 days after the grafting, the cells of the polymorphonuclear leucocyte (PMN) series and eosinophilic granulocytes predominated, but macrophages were not observed at any stages examined. Plasma cells occurred occasionally at later stages (40-60 days) of allograft rejection, but lymphocytes were rarely found at any stages of graft rejection. These observations, combined with the recent finding of the antibody-enhanced phagocytic activity of granulocyte-series cells in the lamprey, indicate that PMNs, but not lymphocytes, function as the major effector cells in allograft rejection in this phylogenetically oldest class of contemporary vertebrates.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Fujii T,Hayakawa Idoi
10.1007/BF00222182subject
Has Abstractpub_date
1983-01-01 00:00:00pages
301-12issue
2eissn
0302-766Xissn
1432-0878journal_volume
231pub_type
杂志文章abstract::Regions within frog semitendinosus muscle that are rich in tonic muscle cells were identified histochemically by myosin adenosine triphosphatase- and succinic dehydrogenase-staining procedures. Bundles of cells still attached to tendinous insertions were removed from those sites, prepared for electron microscopy and s...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00213937
更新日期:1986-01-01 00:00:00
abstract::Light and electron microscopic autoradiography has been employed to define the neuroanatomical patterns of uptake and binding of radiolabelled L-dopa in the endocrine hypothalamus of the rat. A dorsomedial continuum of arcuate and periventricular neurons selectively sequester 3HL-dopa 20 min following its intraventric...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00233675
更新日期:1978-12-14 00:00:00
abstract::Gill lamellae of a bivalve Anodonta woodiana lauta (v. Martens) were observed by electron microscopy. The Anodonta gill wall consists of a single layer of epithelial cells, its basal lamina and the underlying connective tissue layer. It was confirmed that there is no true endothelium in the vessels and that the connec...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00222069
更新日期:1975-01-01 00:00:00
abstract::The evolution of aquaporin-5 (AQP5) expression during postnatal development has not been defined in the sweat gland. Previous studies have suggested that AQP isoforms in several peripheral targets are regulated by a neural mechanism. We have examined, in rat sweat glands, the expression of AQP5 during postnatal develo...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-007-0399-1
更新日期:2007-07-01 00:00:00
abstract::To investigate the mechanisms whereby annular gap junctions in the papillary cells of the enamel organ are degraded intracellularly, continuously growing rat incisors were examined by electron microscopy of routine thin sections as well as for the cytochemical localization of inorganic trimetaphosphatase activity. Rou...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00215192
更新日期:1986-01-01 00:00:00
abstract::A detailed chronological electron-microscopic study of the bone remodeling sequence has been performed in the rat based on a previously described model (Tran Van et al. 1982) in which the remodeling activity is synchronized. This allowed the observation of the cellular and extracellular events during the bone remodeli...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00214682
更新日期:1982-01-01 00:00:00
abstract::The colocalization of immunoreactivities to substance P and calcitonin gene-related peptide (CGRP) in nervous structures and their correlation with other peptidergic structures were studied in the stellate ganglion of the guinea pig by the application of double-labelling immunofluorescence. Three types of fibre were d...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00318563
更新日期:1993-06-01 00:00:00
abstract::Changes in intestinal function, notably impaired transit, following ischemia/reperfusion (I/R) injury are likely to derive, at least in part, from damage to the enteric nervous system. Currently, there is a lack of quantitative data and methods on which to base quantitation of changes that occur in enteric neurons. In...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-010-1126-x
更新日期:2011-04-01 00:00:00
abstract::The distribution and ultrastructure of the mitochondria-rich (MR) cells in the gills of larval (ammocoetes) and adult lampreys (Petromyzon marinus and Geotria australis) have been studied. One type of MR cell, which is found only in ammocoetes, occurs in groups on and between gill lamellae. Freeze-fracture replicas sh...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051003
更新日期:1998-02-01 00:00:00
abstract::alpha-Smooth muscle (alpha SM) actin of endothermic vertebrates is selectively recognized by the monoclonal antibody anti-alpha SM-1. Immunoreactivity to this antibody has been shown to be localized in the NH2-terminal sequence Ac-EEED (Chaponnier et al. 1994). Among terrestrial ectothermic vertebrates, two amphibian ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00417867
更新日期:1995-09-01 00:00:00
abstract::Type 1 diabetes is an autoimmune disorder characterized by a lack of insulin production by the beta cells of the pancreas. This lack of insulin causes a variety of systemic effects on whole-body metabolism. Poorly managed type 1 diabetes can lead to cardiovascular disease, diabetic neuropathy, and diabetic retinopathy...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-012-1387-7
更新日期:2012-09-01 00:00:00
abstract::The expression of the gene for vasoactive intestinal polypeptide (VIP) and peptide histidine methionine (PHM) in the human gastrointestinal tract was studied by in situ hybridization and Northern blotting for PHM/VIP mRNA and immunocytochemistry using specific antisera against the bioactive peptides PHM and VIP. In th...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00306108
更新日期:1994-05-01 00:00:00
abstract::Human gingival fibroblasts were cultured with collagen fibrils. The precise process of collagen phagocytosis and the relationship between acid phosphatase activity and intracellular degradation of collagen were investigated by cytochemical methods at the ultrastructural level. The collagen fibrils were first engulfed ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00213929
更新日期:1986-01-01 00:00:00
abstract::The ultrastructure of adult male rat pinealocytes was studied after orchidectomy and orchidectomy followed by LH-RH administration. Castration causes an increased development of the rough endoplasmic reticulum and the Golgi apparatus as well as an increase in the number of lipid droplets and lysosomes. The changes aft...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219145
更新日期:1976-04-02 00:00:00
abstract::A multilamellate body (MLB), bearing close resemblance to an array of annulate lamellae, has been observed in several adenohypophysial cell types of the teleost, Hemihaplochromis philander. In longitudinal section, each MLB comprises a ladder-like row of 12-50 sausage-shaped profiles, termed lamellae. A few lamellae i...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221372
更新日期:1976-10-06 00:00:00
abstract::The immunocytochemical localization of bovine oviduct-specific glycoproteins was investigated by light and electron microscopy. Using monoclonal antibodies (MAbs) specific for bovine oviductal glycoproteins, 3 regions (fimbriae, ampulla, and isthmus) of the epithelium in the bovine oviduct we studied during the follic...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00327983
更新日期:1993-10-01 00:00:00
abstract::The fine structure of boar Leydig cells is re-examined in samples post-fixed with OSO4-K4Fe(CN)6, an elective method to preserve the ultrastructural detail of the endocrine testis. The cells show a pleomorphic arrangement of the smooth endoplasmic reticulum. Large "vesicle-like" dilatations are interspersed in the tub...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00211483
更新日期:1983-01-01 00:00:00
abstract::Besides its function at cholinergic synapses, acetylcholinesterase (AChE) exerts structural functions on neural differentiation, independent of its enzymatic activity. To elucidate such functions, we have previously heterologously expressed AChE in histotypic retinal reaggregates, revealing strong effects on their his...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410100444
更新日期:2001-11-01 00:00:00
abstract::We report here on cholinergic neurons in the rat hippocampal formation that were identified by immunocytochemistry employing a monoclonal antibody against choline acetyltransferase (ChAT), the acetylcholine-synthesizing enzyme. In general, ChAT-immunoreactive cells were rare, but were observed in all layers of the hip...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00215891
更新日期:1986-01-01 00:00:00
abstract::Pituitaries from normal, young and adult male rats were fixed either in sublimate-formalin or in glutaraldehyde-osmium. In adjacent Paraplast sections, almost all the gonadotrophs were immunostained with both LH and FSH antisera. The rat LH beta and FSH antisera used were shown to be highly specific by the absorption ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00233820
更新日期:1981-01-01 00:00:00
abstract::Guanosine triphosphatase (GTPase) activity was studied histo- and cytochemically in the rod outer segments of the rat retina by means of a newly developed method. Differences in the distribution pattern of the enzyme activity exist within the outer segment: the activity is more intense at the tip of the rod outer segm...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00217416
更新日期:1983-01-01 00:00:00
abstract::Since their introduction to biological imaging, quantum dots (QDs) have progressed from a little known, but attractive, technology to one that has gained broad application in many areas of biology. The versatile properties of these fluorescent nanoparticles have allowed investigators to conduct biological studies with...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-014-2087-2
更新日期:2015-04-01 00:00:00
abstract::Although the cerebrospinal fluid-contacting neurons of the avian paraventricular organ exhibit considerable amounts of catecholamines, they show no tyrosine hydroxylase immunoreactivity. In the quail embryo, the development of these neurons has been studied using the paraformaldeyde-glutaraldeyde method for the fluore...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00307970
更新日期:1995-07-01 00:00:00
abstract::Antithrombin (AT), which is mainly synthesized in the liver, is an acute-phase plasma protein in mammalian species. Here, we demonstrated that sheep anti-human AT antibody cross-reacted with the humoral fluids in amphioxus Branchiostoma belcheri tsingtauense as well as human serum. The concentration of AT in the humor...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-005-0088-x
更新日期:2006-03-01 00:00:00
abstract::Satellite cells can be isolated from skeletal muscle biopsies, activated to proliferating myoblasts and differentiated into multinuclear myotubes in culture. These cell cultures represent a model system for intact human skeletal muscle and can be modulated ex vivo. The advantages of this system are that the most relev...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-013-1655-1
更新日期:2013-12-01 00:00:00
abstract::Serial sections of human vaginal and keratinized oral-gingival epithelia were investigated for ciliary structures. Most melanocytes of the gingival epithelium lacked cilia, whereas almost all basal keratinocytes of the deeper portion of the epithelial ridges possessed one cilium each. In the suprabasal layers of the r...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00215830
更新日期:1988-02-01 00:00:00
abstract::During the reproductive period of the male stickleback, structural and functional changes of the kidney take place, both in the glomeruli and in the renal tubule cells. The structural changes in the glomeruli involve almost all glomerular components and point to a reduction of the glomerular filtration rate. The purpo...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00210146
更新日期:1981-01-01 00:00:00
abstract::Seven isoforms of tachykinin-related peptides (TRPs) have been isolated from the brain of the cockroach Leucophaea maderae. These peptides (LemTRP-1, 2, and 5-9) share the C-terminal sequence GFX(1)GX(2)Ramide (where X(1) and X(2) are variable residues). In order to determine the neuronal distribution of several of th...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-002-0538-7
更新日期:2002-05-01 00:00:00
abstract::Surface features of the ependymal linings of the fourth ventricle in the fowl were analyzed employing the scanning electron microscope (SEM). On the floor of the median sulcus, each ependymal cell has a solitary cilium, whereas on both sides of the sulcus, cilia are so densely distributed that the details of the under...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00233562
更新日期:1979-03-09 00:00:00
abstract::The endothelial layer of blood vessels controls the passage of cells and solutes from the blood into the surrounding tissue. Crucial for this regulation is the integrity of endothelial cell-cell junctions. Various molecular mechanisms control junctional integrity of the endothelial layer including GTPases, modulation ...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-014-1812-1
更新日期:2014-03-01 00:00:00