Fate of annular gap junctions in the papillary cells of the enamel organ in the rat incisor.

Abstract:

:To investigate the mechanisms whereby annular gap junctions in the papillary cells of the enamel organ are degraded intracellularly, continuously growing rat incisors were examined by electron microscopy of routine thin sections as well as for the cytochemical localization of inorganic trimetaphosphatase activity. Routine thin-section analysis revealed small flat or undulated gap junctions, hemi-annular gap junctions between an invaginated cell process and a cell body, and fully internalized cytoplasmic annular gap junctions. Both hemi-annular and annular gap junctions usually contain various organelles and/or inclusions, such as mitochondria, endoplasmic reticulum, ribosomes, vesicles, and lysosomes in the cytoplasm confined by the junctional membranes. Annular gap junctions are sometimes fused with vesicular or tubulovesicular structures. Cytochemistry of inorganic trimetaphosphatase activity revealed an intense enzymatic reaction within a system of tubular structures and round or oval dense bodies. Both structures are believed to correspond to primary lysosomes. A part of the Golgi apparatus also shows a weak reaction. Although hemi-annular gap junctions never show enzymatic reaction, annular gap junctions sometimes contain reaction products throughout their interior cytoplasm and inclusions. Fusion of annular gap-junctional membranes with reaction-positive tubular structures is also observed. In one instance, revealed in serial sections, an annular gap junction was encircled entirely by a reaction-positive structure. These results suggest that cytoplasmic annular gap junctions are formed by endocytosis of hemi-annular gap junctional membranes from the cell surface and then degraded intracellularly by lysosomal enzymes.

journal_name

Cell Tissue Res

journal_title

Cell and tissue research

authors

Sasaki T,Garant PR

doi

10.1007/BF00215192

subject

Has Abstract

pub_date

1986-01-01 00:00:00

pages

523-30

issue

3

eissn

0302-766X

issn

1432-0878

journal_volume

246

pub_type

杂志文章
  • Induction by progesterone of a sexual dimorphism of estrogen uptake by anterior pituitary cells in situ.

    abstract::The effects of progesterone pretreatment on in vivo 3H-estrogen uptake by five anterior pituitary cell types was analyzed by means of a quantitative autoradiographic-immunocytochemical technique. Male and female rats castrated for 14 days show nuclear concentration of label in all five cell types one h after injection...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00236250

    authors: Keefer DA

    更新日期:1981-01-01 00:00:00

  • Primary culture of antennal mechanoreceptor neurons of Manduca sexta.

    abstract::We have developed a primary cell culture system of antennal mechanoreceptor neurons from early-stage pupal sphinx moth Manduca sexta. Dissociated neurons from the moth antennae differentiated, grew and survived for several weeks in a conditioned culture medium. Bipolar neurons with soma diameters of 10-25 microns from...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s004410051358

    authors: Torkkeli PH,French AS

    更新日期:1999-08-01 00:00:00

  • Enzyme histochemical characteristics of osteoblasts and mononucleated osteoclasts in a teleost fish with acellular bone (Oreochromis niloticus, Cichlidae).

    abstract::Bone resorption by mononucleated cells was studied in the acellular bone of a teleost fish (Oreochromis niloticus) by histological and enzyme histochemical observations and by transmission electron microscopy. Bone resorbing cells (osteoclasts) were identified by their location at the sites of bone resorption, their f...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s004410050782

    authors: Witten PE,Bendahmane M,Abou-Haila A

    更新日期:1997-02-01 00:00:00

  • Ultrastructural changes in the spiral limbus associated with carboplatin-induced ablation of inner hair cells.

    abstract::Four months after the selective ablation of inner hair cells by carboplatin, the interdental cell epithelium exhibited dilated intercellular spaces and cytosolic vacuoles not seen in controls. In addition, the wide, often electron-lucent phalanges observed in the interdental cells of the normal chinchilla collapsed in...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s004410000253

    authors: Spicer SS,Salvi RJ,Schulte BA

    更新日期:2000-10-01 00:00:00

  • The carbohydrates of secretory granules and the glycocalyx in developing mucoid cells.

    abstract::Complex carbohydrates in secretory granules and at the apical cell surface of mouse gastric mucoid cells were studied during embryogenesis and in the early postnatal period by various cytochemical methods; the periodic acid-thiocarbohydrazide-silver proteinate (PA-TCH-SP) and tannic acid-uranyl acetate (TA-UA) procedu...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00214559

    authors: Pipan N,Psenicnik M

    更新日期:1985-01-01 00:00:00

  • Protective effects of the neuropeptide PACAP in diabetic retinopathy.

    abstract::Pituitary adenylate cyclase activating polypeptide (PACAP) is a neuropeptide with highly potent neurotrophic and neuroprotective effects. PACAP and its receptors occur in the retina and PACAP has been applied in animal models of metabolic retinal disorders to reduce structural and functional damage. Furthermore, PACAP...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-012-1349-0

    authors: Szabadfi K,Atlasz T,Kiss P,Reglodi D,Szabo A,Kovacs K,Szalontai B,Setalo G Jr,Banki E,Csanaky K,Tamas A,Gabriel R

    更新日期:2012-04-01 00:00:00

  • Effect of alpha-fluoromethylhistidine-evoked histamine depletion on ultrastructure of endocrine cells in acid-producing mucosa of stomach in mouse, rat and hamster.

    abstract::The oxyntic mucosa of the mammalian stomach is rich in endocrine cells, such as ECL cells, A-like cells, somatostatin cells, D1/P cells and, in some species, enterochromaffin cells. The various endocrine cell types can be distinguished on the basis of their characteristic cytoplasmic granules and vesicles. The ECL cel...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s004410050707

    authors: Andersson K,Zhao CM,Chen D,Sundler F,Hâkanson R

    更新日期:1996-12-01 00:00:00

  • The fine structure of the carapace integument of Daphnia magna Straus (Crustacea Branchiopoda).

    abstract::The structure of the two integumental layers comprising the carapace of female D. magna was examined at several points through the molt cycle. The epicuticle and procuticle are simple in organisation; pore canalsare absent but intracuticular fibres are present, forming complexes with invaginations of the epidermal pla...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00214213

    authors: Halcrow K

    更新日期:1976-06-14 00:00:00

  • CRF-containing neurons of the rat hypothalamus.

    abstract::The immunoreactive CRF-neurons of the rat hypothalamus have been examined immunohistochemically employing anti-rat CRF serum. These neurons are confined to the paraventricular nucleus, dorsomedial-lateral hypothalamic area, and suprachiasmatic nucleus, and are, respectively, also immunoreactive to anti-Met-enk, -alpha...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00216347

    authors: Daikoku S,Okamura Y,Kawano H,Tsuruo Y,Maegawa M,Shibasaki T

    更新日期:1985-01-01 00:00:00

  • Immune-complex-trapping cells in the spleen of the oriental fire-bellied toad, Bombina orientalis.

    abstract::The spleen of the oriental fire-bellied toad, Bombina orientalis, consists of well-developed white pulp, separated from the lymphocytic marginal zone by the connective tissue boundary layer. Injection of peroxidase-conjugated rabbit anti-peroxidase revealed that these immune complexes were localized on the surface of ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00297553

    authors: Dulak J,Bauer J,Döpp EA,Van Rooijen N

    更新日期:1993-01-01 00:00:00

  • Uptake and transport of immunoglobulin by the chick choroid plexus. I. Studies with enzyme-treated human immunoglobulin in tissue culture.

    abstract::The choroid plexus from the lateral ventricles of 18-day chick embryos was cultivated as an organ in medium 199 until the degeneration of the stroma. Selected plexuses forming an empty epithelial sac were then incubated with enzyme-treated human immunoglobulin (5S-antibody) and with native human immunoglobulin (7S-ant...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00237886

    authors: Vollerthun R,Möller W

    更新日期:1980-01-01 00:00:00

  • Immunocytochemical analysis of misplaced rhodopsin-positive cells in the developing rodent retina.

    abstract::During the first postnatal weeks of the developing rodent retina, rhodopsin can be detected in a number of neuron-like cells in the inner retina. In the present study, we aim to characterize the morphology, number and staining characteristics of this peculiar population. Misplaced rhodopsin-positive cells (MRCs) were ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-013-1788-2

    authors: Szabó K,Szabó A,Enzsöly A,Szél A,Lukáts A

    更新日期:2014-04-01 00:00:00

  • Insights into the evolution of digestive systems from studies of Trichoplax adhaerens.

    abstract::Trichoplax, a member of the phylum Placozoa, is a tiny ciliated marine animal that glides on surfaces feeding on algae and cyanobacteria. It stands out from other animals in that it lacks an internal digestive system and, instead, digests food trapped under its lower surface. Here we review recent work on the phenotyp...

    journal_title:Cell and tissue research

    pub_type: 杂志文章,评审

    doi:10.1007/s00441-019-03057-z

    authors: Smith CL,Mayorova TD

    更新日期:2019-09-01 00:00:00

  • Regulation of secretory granule formation in chronically hypersecretory melanotrophs in the rat pituitary.

    abstract::The formation of secretory granules in chronically hypersecretory melanotrophs in the rat pituitary was studied. Hypersecretion was induced by treatment with the dopamine antagonist haloperidol (1.5 mg/kg daily for 7 days), which releases the normal neural dopaminergic inhibition of secretion from the melanotroph. Mor...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00319432

    authors: Bäck N,Soinila S

    更新日期:1994-02-01 00:00:00

  • Similarities and differences in the structure of segmentally homologous neurons that control the hearts of the leech, Hirudo medicinalis.

    abstract::The neural circuit that controls the hearts in the leech comprises an ensemble of synaptically interconnected cardiac motor neurons (HE cells) and cardiac interneurons (HN cells). Both the HE cells and the HN cells constitute segmentally homologous sets. We have investigated the structure of these neurons by iontophor...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00235152

    authors: Shafer MR,Calabrese RL

    更新日期:1981-01-01 00:00:00

  • Immunocytochemical localization of a novel pituitary polypeptide "7B2" in the gastro-intestinal tract of the rat.

    abstract::Immunoreactivity to the polypeptide designated "7B2" recently isolated from human and porcine pituitary glands, appears to be consistently confined to neuroendocrine and endocrine cells in various tissues. In rat gut, immunoreactive 7B2 was found in endocrine-paracrine cells. Highly labeled cells were found in the ant...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00217343

    authors: Falgueyret JP,Marcinkiewicz M,Benjannet S,Cantin M,Seidah NG,Chrétien M

    更新日期:1987-09-01 00:00:00

  • Microanatomy of the subumbrellar motor innervation in Aglantha digitale (Hydromedusae: Trachylina).

    abstract::The hydrozoan medusa Aglantha digitale (Müller 1776) has eight syncytical giant motor axons, up to 40 micrometers in diameter, running from the margin, up the inside of the bell towards the apex. Giant motor axons injected with Lucifer Yellow CH are connected with lateral neurons running circumferentially across the s...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF01258491

    authors: Weber C,Singla CL,Kerfoot PA

    更新日期:1982-01-01 00:00:00

  • Dislocated type-A spermatogonia in human seminiferous tubules.

    abstract::Type-A spermatogonia can be found in different locations throughout the germinal epithelium of human seminiferous tubules. Generally they represent the population of germ cells adjacent to the basal lamina, but under special conditions they may be located in the adluminal compartment. This aberrant location is found n...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00216510

    authors: Holstein AF,Bustos-Obregón E,Hartmann M

    更新日期:1984-01-01 00:00:00

  • Immuno-cytochemical demonstration, in the external region of the amphibian median eminence, of separate vasotocinergic and mesotocinergic nerve fibres.

    abstract::By means of single and double immuno-enzyme cytochemical staining techniques, it was shown that the external region of the amphibian median eminence contains separate vasotocinergic and mesotocinergic nerve fibres. Moreover, it was demonstrated that the vasotocinergic fibres also contain neurophysin. In animals in whi...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00221117

    authors: Dierickx K,Vandesande F

    更新日期:1977-02-02 00:00:00

  • Immunohistochemical observation of growth-associated protein 43 (GAP-43) in the developing circumvallate papilla of the rat.

    abstract::The distribution and development of growth-associated protein 43 (GAP-43)-like immunoreactivity (-LI) in the rat circumvallate papilla (CVP) were compared to those of protein gene product 9.5 (PGP 9.5)-LI. In the adult, thick GAP-43-like immunoreactive (-IR) structures gathered densely in the subgemmal region. Some of...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s004410051142

    authors: Wakisaka S,Daikoku H,Miyawaki Y,Youn SH,Maeda T,Kurisu K

    更新日期:1998-09-01 00:00:00

  • Ultrastructural changes in contents of membrane-coating granules after extrusion from epithelial cells of hamster cheek pouch.

    abstract::Membrane-coating granules of the epithelium of the hamster cheek pouch displayed a lamellated internal structure consisting of alternating thick and thin electron dense bands separated by translucent bands of equal width. The repeat distance of the contents was 8.5 nm +/- sd. 0.7 nm and the thickness of the major elec...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00224374

    authors: Hayward AF

    更新日期:1978-02-24 00:00:00

  • Two types of mammosomatotropes in mouse adenohypophysis.

    abstract::Two types of mammosomatotropes (MS), the small-granule and vesicle-granule MS, were detected in mouse adenohypophysis by electron microscopy and immunohistochemistry. Both cell-types were immunoreactive to prolactin (PRL) and growth hormone (GH) antisera. The small-granule MS contained small, round, solid secretory gr...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00225615

    authors: Sasaki F,Iwama Y

    更新日期:1989-06-01 00:00:00

  • Insulin receptors in the pituitary gland: morphological evidence for influence on opioid peptide-synthesizing cells.

    abstract::Previous investigations have demonstrated that peripheral insulin has a significant influence on brain function and that the interaction of insulin with neuropeptides in neuroendocrine regions may be pivotal for the regulation of body metabolism and energy balance. Since the various levels of interactions are only inc...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s004410050833

    authors: Unger JW,Lange W

    更新日期:1997-06-01 00:00:00

  • Ultastructural localization of polysaccharides in the vacuolar system of an established cell line.

    abstract::Polysaccharides in the vacuolar system of an established line of monkey kidney epithelial cells, were investigated by high resolution radioautography following incorporation of 3H-fucose and by the periodic acid-thiosemicarbazide-silver proteinate staining method. Significant amounts of glycogen and glycoproteins were...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00225345

    authors: Knecht E,Hernández J

    更新日期:1978-10-30 00:00:00

  • Effects of prolonged sodium restriction on the morphology and function of rat adrenocortical autotransplants.

    abstract::Regenerated adrenocortical nodules were obtained by implanting fragments of the capsular tissue of excised adrenal glands into the musculus gracilis of rats (Belloni et al. 1990). Five months after the operation, operated rats showed a normal basal blood level of corticosterone, but a very low concentration of circula...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00318136

    authors: Belloni AS,Neri G,Andreis PG,Musajo FG,Boscaro M,Mazzocchi G,Nussdorfer GG

    更新日期:1991-07-01 00:00:00

  • The possible protective role of zinc oxide nanoparticles (ZnONPs) on testicular and epididymal structure and sperm parameters in nicotine-treated adult rats (a histological and biochemical study).

    abstract::Exposure to nicotine in smoking contributes to most unexplained male infertility but the mechanisms remain to be fully elucidated. Zinc (Zn) is an essential trace element in normal growth, development and reproduction. Zinc oxide nanoparticles (ZnONPs) are well-known antioxidants. Therefore, this work was designed to ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-018-2909-8

    authors: Mohamed DA,Abdelrahman SA

    更新日期:2019-02-01 00:00:00

  • A freeze-fracture study of perinatal changes of intramembranous particles in microvilli of absorptive cells in mouse small intestine.

    abstract::Perinatal changes in the appearance of intramembranous particles (IMPs) of microvilli of enterocytes were analyzed quantitatively. In both the jejunum and the ileum, the IMP density on the P-face showed no significant changes from day 17 of gestation to day 5 of postnatal life. It increased between day 5 and day 12, r...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00212224

    authors: Arima T,Yamamoto T

    更新日期:1983-01-01 00:00:00

  • The histological architecture of the auditory organs in the parasitoid fly Ormia ochracea.

    abstract::Gravid females of the parasitoid fly species Ormia ochracea (Diptera: Tachinidae) rely on their sense of hearing to detect and localize their hosts, field crickets of the genus Gryllus. As in any hearing insect species, the fly's auditory system consists of a rather complex cascade of mechanical and physiological mech...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s004410000257

    authors: Robert D,Willi U

    更新日期:2000-09-01 00:00:00

  • Expression of synaptogyrin-1 in T1R2-expressing type II taste cells and type III taste cells of rat circumvallate taste buds.

    abstract::Synaptogyrins are conserved components of the exocytic apparatus and function as regulators of Ca(2+)-dependent exocytosis. The synaptogyrin family comprises three isoforms: two neuronal (synaptogyrin-1 and -3) and one ubiquitous (synaptogyrin-2) form. Although the expression patterns of the exocytic proteins synaptot...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-013-1629-3

    authors: Kotani T,Toyono T,Seta Y,Kitou A,Kataoka S,Toyoshima K

    更新日期:2013-09-01 00:00:00

  • Studies on intracellular transport of secretory proteins in the rat exocrine pancreas. IV. Stimulation by in vivo infusion of caerulein.

    abstract::Prolonged secretory stimulation of the exocrine pancreas in the rat by in vivo infusion of caerulein leads to a rapid degranulation of the organ associated with a progressive reduction in the size of the zymogen granules. During the first six to twelve hours of stimulation Golgi complexes are enlarged and several stru...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00224474

    authors: Bieger W,Martin-Achard A,Bassler M,Kern HF

    更新日期:1976-01-28 00:00:00