Two types of mammosomatotropes in mouse adenohypophysis.

Abstract:

:Two types of mammosomatotropes (MS), the small-granule and vesicle-granule MS, were detected in mouse adenohypophysis by electron microscopy and immunohistochemistry. Both cell-types were immunoreactive to prolactin (PRL) and growth hormone (GH) antisera. The small-granule MS contained small, round, solid secretory granules about 100 nm in diameter, and were smaller than the classical GH and PRL cell-types. The vesicle-granule MS contained secretory granules like cored vesicles, and were larger than classical GH and PRL cells. Small-granule MS were immunoreactive to both PRL and GH antisera in the same region of the cell cytoplasm; the vesicle-granule MS, however, were immunoreactive to only PRL antiserum in most cytoplasmic areas, and a positive response to both PRL and GH antisera was confined to only certain small areas.

journal_name

Cell Tissue Res

journal_title

Cell and tissue research

authors

Sasaki F,Iwama Y

doi

10.1007/BF00225615

subject

Has Abstract

pub_date

1989-06-01 00:00:00

pages

645-8

issue

3

eissn

0302-766X

issn

1432-0878

journal_volume

256

pub_type

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