Abstract:
:Light and electron microscopic autoradiography has been employed to define the neuroanatomical patterns of uptake and binding of radiolabelled L-dopa in the endocrine hypothalamus of the rat. A dorsomedial continuum of arcuate and periventricular neurons selectively sequester 3HL-dopa 20 min following its intraventricular infusion. By 40 and 60 min following the infusion labelling of neurons is minimal and supports the notion of rapid degradation. Other cell compartments such as tanycytes demonstrate uptake of 3H L-dopa. The ultrastructural localization and distribution of radiolabelled L-dopa (or its metabolites) in the rodent hypothalamus is discussed with respect to mechanisms and cell compartments involved in neuroendocrine regulatory processes.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Scott DE,Scott PM,Krobisch-Dudley Gdoi
10.1007/BF00233675subject
Has Abstractpub_date
1978-12-14 00:00:00pages
29-43issue
1eissn
0302-766Xissn
1432-0878journal_volume
195pub_type
杂志文章abstract::Kruppel-like factor 4 (KLF4) is a zinc-finger-type transcription factor with a restricted expression pattern during skeletal development. We have previously shown that KLF4 represses osteoblast mineralization concomitant with a down-regulation in the expression of a number of osteoblastic genes, both in vivo and in vi...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-014-1931-8
更新日期:2014-10-01 00:00:00
abstract::The amygdala is a central hub for fear learning assessed by Pavlovian fear conditioning. Indeed, the prevailing hypothesis that learning and memory are mediated by changes in synaptic strength was shown most convincingly at thalamic and cortical afferents to the lateral amygdala. The neurotrophin brain-derived neurotr...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-020-03260-3
更新日期:2020-10-01 00:00:00
abstract::Intracerebroventricular (ICV) injection of melanin-concentrating hormone (MCH) influences feeding behavior in the goldfish and exerts an anorexigenic action in goldfish brain, unlike its orexigenic action in mammals. Despite a growing body of knowledge concerning MCH function in mammals, the role of MCH in appetite ha...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-006-0347-5
更新日期:2007-05-01 00:00:00
abstract::In the central nervous system of the male domestic flow, metenkephalin (ENK) immunoreactive perikarya and fiber tracts as well as extensive but sharply delimited fiber networks were visualized by means of the PAP technique. The most striking results were: (1) The demonstration of an association of ENK-containing struc...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00236920
更新日期:1980-01-01 00:00:00
abstract::The presence, location and degree of immunoexpression of various microfilament (MF) and intermediate filament (IF) systems (actin, cytokeratins, desmin, vimentin) were studied in the excurrent ducts of the testis in sexually mature and active galliform (Japanese quail, domestic fowl, turkey) and anseriform (duck) bird...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-008-0631-7
更新日期:2008-08-01 00:00:00
abstract::Aquaporins (AQPs) are integral membrane proteins that function as channels for the transfer of water and small solutes across membranes. In mammalian cells, 13 isoforms (AQP0-12) have been identified, and these exhibit unique patterns of expression in various cell types and tissues. Among these isoforms, AQP6 is consi...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-007-0558-4
更新日期:2008-04-01 00:00:00
abstract::Haemophilic arthropathy is the major cause of disability in patients with haemophilia and, despite prophylaxis with coagulation factor concentrates, some patients still develop articular complications. We evaluate the feasibility of a tissue engineering approach to improve current clinical strategies for cartilage reg...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-016-2408-8
更新日期:2016-10-01 00:00:00
abstract::Fibroblast growth factors (Fgfs) are proteins with diverse functions in development, repair, and metabolism. The human Fgf gene family with 22 members can be classified into three groups, canonical, intracellular, and hormone-like Fgf genes. In contrast to canonical and intracellular Fgfs identified in invertebrates a...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-010-1024-2
更新日期:2010-10-01 00:00:00
abstract::Gap junctions exist in the septa between the segments of the lateral giant axons in the ventral nerve cord of the crayfish Procambarus. A large increase in the resistance (uncoupling) of these gap junctions was brought about by mechanical injury to the axonal segments. Both thin sections and freeze-fracture preparatio...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00217847
更新日期:1984-01-01 00:00:00
abstract::Endothelial cells separate the intra- and extravascular space and regulate transport processes between these compartments. Since intercellular junctions are required for these specific cell functions, the cell-cell contacts in the permanent cell line ECV304 were systematically analyzed and compared with human umbilica...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051340
更新日期:1999-07-01 00:00:00
abstract::The structure of guppy (Poecilia reticulata) spermatogonia and spermatocytes has been studied using electron microscopy. The spermatogonia, situated at the apex of the seminiferous tubule, are almost all surrounded by a network of Sertoli cells; they have very diffuse chromatin and one or two large nucleoli. The cytop...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00217139
更新日期:1984-01-01 00:00:00
abstract::Thyroid hormone (TH) plays an important role in regulating ovarian development. However, the mechanism involved remains unclear. Evidence suggests that glucose is essential for ovarian development, and its uptake is mediated by several glucose transporter proteins (Glut). We have investigated the effects of TH on Glut...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-016-2453-3
更新日期:2016-11-01 00:00:00
abstract::Complex intracellular inclusion bodies of the Biondi type were observed in the choroidal epithelium (choroid plexus of the lateral ventricle) of a 43-year-old male chimpanzee. The specific components of these inclusions are bundles of filaments 8-15 nm in diameter, which are associated with lipid droplets and a wide v...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00217876
更新日期:1984-01-01 00:00:00
abstract::An electron-microscopic study of the myotendinous portion of the diaphragm in the Wistar rat has shown that at the ends of muscle fibers, longitudinally oriented invaginations and peripheral furrows of the sarcolemma establish specialized contacts with individual sacs of the sarcoplasmic reticulum. The construction of...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00251058
更新日期:1986-01-01 00:00:00
abstract::The cellular response of non-neuronal elements of the pyramidal cell layer of the rat hippocampus, especially the area CA3, was observed electron microscopically following destruction of this formation by means of intraventricular administration of kainic acid (KA). The neuroglial cell types responding to the KA-induc...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00238652
更新日期:1981-01-01 00:00:00
abstract::Mice and rats emit and perceive calls in the ultrasonic range, i.e., above the human hearing threshold of about 20 kHz: so-called ultrasonic vocalizations (USV). Juvenile and adult rats emit 22-kHz USV in aversive situations, such as predator exposure and fighting or during drug withdrawal, whereas 50-kHz USV occur in...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-013-1607-9
更新日期:2013-10-01 00:00:00
abstract::The ultrastructural localisation of acid phosphatases (AcPhs) during the normal daily breakdown of rhabdomere membrane in Dinopis has been examined using beta-glycerophosphate and p-nitrophenyl phosphate as substrates. Results are related to the classification of organelles in the receptors given by Blest, Powell and ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00236082
更新日期:1979-07-17 00:00:00
abstract::The distribution and interconnections of brainstem catecholamine cell groups thought to be important in cardiovascular control were studied using histochemical and ultrastructural techniques in the rabbit. Lesions and microinjections of horseradish peroxidase (HRP) were made in the nucleus tractus solitarii in the dor...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00209963
更新日期:1981-01-01 00:00:00
abstract::The chemical composition of intermediate filaments (IF's) in the ependyma of the subcommissural organ (SCO) of the Mongolian gerbil (Meriones unguiculatus) was investigated immunohistochemically in paraffin-embedded tissue. Antibodies against glial fibrillary acidic protein (GFAP), vimentin, neurofilament proteins and...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218796
更新日期:1989-03-01 00:00:00
abstract::The afferent lymphatic vessels of rat popliteal lymph nodes were interrupted, and the histological alterations in the lymph nodes occurring 1 to 14 weeks after operation were studied. One week after operation the number of macrophages was considerably reduced and continued to decrease during the subsequent time period...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00234394
更新日期:1980-01-01 00:00:00
abstract::The presence of melatonin is demonstrated in the pineal gland, the retina and the Harderian gland in some mammalian and non-mammalian vertebrates, using a specific fluorescence labelled antibody technique. Four different potent antibodies against melatonin have been used and compared. In the pineal gland of hamsters, ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00233830
更新日期:1981-01-01 00:00:00
abstract::The analysis of myenteric neurons is becoming increasingly important for the assessment of enteric nervous system injury and degeneration occurring in motor disorders of the gut. Limited information is presently available on the quantitative estimation of myenteric neurons and glial cells in paraffin-embedded colonic ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-009-0770-5
更新日期:2009-05-01 00:00:00
abstract::The innervation of the uterus in the ovoviviparous urodele Salamandra salamandra was studied. In whole mount preparations of the thin-walled uterus of pregnant females, a dense adrenergic network was demonstrated using a modified glyoxylic acid fluorescence technique. Based on vesicle type and cytochemical reactivity ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00213797
更新日期:1983-01-01 00:00:00
abstract::Vasodilator-stimulated phosphoprotein (VASP) and mammalian-enabled protein (MENA) share similar cellular localisation and functions (signal transduction pathways, regulation of actin cytoskeleton dynamics). Functional substitution and compensation among Ena/VASP proteins have been proposed as the reason for the absenc...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-004-0964-9
更新日期:2004-12-01 00:00:00
abstract::An antiserum against the octapeptide Pea-CAH-I, a member of the adipokinetic hormone/red pigment-concentrating hormone family, has been produced for immunocytochemical staining in insects and various other invertebrate species. The anti-Pea-CAH-I serum stains the glandular corpora cardiaca cells of those insect specie...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050601
更新日期:1996-06-01 00:00:00
abstract::Using isoenzyme-specific antisera, we have studied the distribution of protein kinase C isoforms in fetal mouse organs at the developmental age of 17 days. Two different sets of antibodies, produced by different manufacturers, were employed in this study. The specificity of the antisera was tested by immunoblotting ex...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00318364
更新日期:1995-06-01 00:00:00
abstract::The enteric nervous system appears to play a pivotal role in the functional recovery of the gastrointestinal tract after partial resection and reanastomosis, but the structural changes following surgery are not fully understood. The present study was designed to clarify the processes of myenteric plexus regeneration u...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00327773
更新日期:1994-08-01 00:00:00
abstract::Right superior cervical sympathectomy was performed in one-day old rats. This operation had a small but definite effect on the postnatal development of the submandibular gland. The gland on the sympathectomized side weighed less and contained smaller amounts of DNA, RNA and protein than the contralateral intact gland....
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00227032
更新日期:1977-05-10 00:00:00
abstract::The wall of the seminiferous tubule in rodents consists of an inner layer of myoid cells covered by an outer layer of endothelial cells. Myoid cells are a type of smooth muscle cell containing α-actin filaments arranged in two independent layers that contract when stimulated by endothelin-1. The irregular surface reli...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-016-2386-x
更新日期:2016-08-01 00:00:00
abstract::Growing numbers of translational genomics studies are based on the highly efficient and versatile zebrafish (Danio rerio) vertebrate model. The increasing types of zebrafish models have improved our understanding of inherited kidney diseases, since they not only display pathophysiological changes but also give us the ...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-017-2593-0
更新日期:2017-07-01 00:00:00