Biphasic effects of muramyl dipeptide or lipopolysaccharide on superoxide anion-generating activities of macrophages.

abstract：:Attachment and ingestion of Mycobacterium avium subsp. paratuberculosis by two epithelial cell lines were enhanced by soluble fibronectin (FN). Peptide blocking of the FN attachment protein (FAP-P) inhibited the internalization of M. avium subsp. paratuberculosis. Disruption of FAP-P expression significantly reduced a...

journal_title：Infection and immunity

authors： Secott TE,Lin TL,Wu CC

更新日期：2002-05-01 00:00:00

abstract：:Current vaccination against Streptococcus pneumoniae uses vaccines based on capsular polysaccharides from selected serotypes and has led to nonvaccine serotype replacement disease. We have investigated an alternative serotype-independent approach, using multiple-antigen vaccines (MAV) prepared from S. pneumoniae TIGR4...

journal_title：Infection and immunity

authors： Chan WY,Entwisle C,Ercoli G,Ramos-Sevillano E,McIlgorm A,Cecchini P,Bailey C,Lam O,Whiting G,Green N,Goldblatt D,Wheeler JX,Brown JS

更新日期：2019-02-21 00:00:00

abstract：:Natural killer (NK) cells are critically involved in the early immune response against various intracellular pathogens, including Coxiella burnetii and Chlamydia psittaciChlamydia-infected NK cells functionally mature, induce cellular immunity, and protect themselves by killing the bacteria in secreted granules. Here,...

journal_title：Infection and immunity

authors： Matthiesen S,Zaeck L,Franzke K,Jahnke R,Fricke C,Mauermeir M,Finke S,Lührmann A,Knittler MR

更新日期：2020-10-19 00:00:00

abstract：:The efficacy of the innate immune system depends on its ability to mount an appropriate response to diverse infections and damaging agents. Key components of this system are pattern recognition receptors that detect pathogen-associated and damage-associated molecular patterns (PAMPs and DAMPs). Nlrp1b is a pattern rec...

journal_title：Infection and immunity

authors： Liao KC,Mogridge J

更新日期：2013-02-01 00:00:00

abstract：:BCG vaccines are a family of closely related daughter strains of an attenuated isolate of Mycobacterium bovis derived by in vitro passage from 1908 to 1921. During subsequent laboratory propagation of the vaccine strain until its lyophilization in 1961, BCG Pasteur underwent at least seven further genomic mutations. T...

journal_title：Infection and immunity

authors： Belley A,Alexander D,Di Pietrantonio T,Girard M,Jones J,Schurr E,Liu J,Sherman DR,Behr MA

更新日期：2004-05-01 00:00:00

abstract：:Gnotobiotic calves were inoculated with an O5:K4:H-, urease-positive strain of Escherichia coli isolated from a 2-day-old calf with diarrhea. The calves developed elevated temperatures and passed loose mucoid feces, with or without blood. The E. coli strain was negative for heat-stable and heat-labile enterotoxins but...

journal_title：Infection and immunity

authors： Moxley RA,Francis DH

更新日期：1986-08-01 00:00:00

abstract：:The salmonid macrophage-like cell line RTS-11 and purified trout pronephros phagocytes were used to analyze in vitro entry and survival of two Streptococcus iniae serotypes. Efficient invasion by S. iniae occurred in both cells, but only the type II strain persisted in pronephros phagocytes for at least 48 h. Ex vivo ...

journal_title：Infection and immunity

authors： Zlotkin A,Chilmonczyk S,Eyngor M,Hurvitz A,Ghittino C,Eldar A

更新日期：2003-05-01 00:00:00

abstract：:A monoclonal antibody (MAb) to Candida albicans (MAb B6.1) that protects against candidiasis and the nonprotective MAb B6 were compared for ability to support neutrophil (polymorphonuclear leukocyte [PMN]) candidacidal activity. Both MAbs are immunoglobulin M, and each recognizes distinct C. albicans mannan cell wall ...

journal_title：Infection and immunity

authors： Caesar-TonThat TC,Cutler JE

更新日期：1997-12-01 00:00:00

abstract：:The virulence of Candida albicans in a mouse model of invasive candidiasis is dependent on the phospholipids phosphatidylserine (PS) and phosphatidylethanolamine (PE). Disruption of the PS synthase gene CHO1 (i.e., cho1Δ/Δ) eliminates PS and blocks the de novo pathway for PE biosynthesis. In addition, the cho1Δ/Δ muta...

journal_title：Infection and immunity

authors： Davis SE,Hopke A,Minkin SC Jr,Montedonico AE,Wheeler RT,Reynolds TB

更新日期：2014-10-01 00:00:00

abstract：:Isolates of Thermoplasma acidophilum were divided into serological groups based on immunodiffusion studies of solubilized-membrane preparations. ...

journal_title：Infection and immunity

authors： Bohlool BB,Brock TD

更新日期：1974-07-01 00:00:00

abstract：:Virus population dynamics in the lungs, trachea, and nasopharynx of Swiss-ICR mice were studied after respiratory challenge with mouse-adapted preparations of strain A2/Aichi/2/68 influenza virus. Markedly higher doses of virus were required to produce infection with nasopharyngeal challenge than with bronchoalveolar ...

journal_title：Infection and immunity

authors： Larson EW,Dominik JW,Rowberg AH,Higbee GA

更新日期：1976-02-01 00:00:00

abstract：:Although cryptococcosis is characterized as a chronic central nervous system disease, it is generally accepted that the lungs are the primary portal of entry for the etiological agent. Despite this, there is a distinct lack of evidence that viable airborne particles of Cryptococcus neoformans are small enough to reach...

journal_title：Infection and immunity

authors： Neilson JB,Fromtling RA,Bulmer GS

更新日期：1977-09-01 00:00:00

abstract：:Group B streptococci (GBS) are the major cause of neonatal pneumonia, sepsis, and meningitis. Steps considered to be important in the pathogenesis of this infection include colonization of the rectum and vagina of the mother, aspiration of GBS into the fetal lung during or just prior to delivery, and invasion of GBS i...

journal_title：Infection and immunity

authors： Tamura GS,Kuypers JM,Smith S,Raff H,Rubens CE

更新日期：1994-06-01 00:00:00

abstract：:We report here the identification and characterization of two zinc uptake systems, ZurAM and ZinABC, in the intracellular pathogen Listeria monocytogenes. Transcription of both operons was zinc responsive and regulated by the zinc-sensing repressor Zur. Deletion of either zurAM or zinA had no detectable effect on grow...

journal_title：Infection and immunity

authors： Corbett D,Wang J,Schuler S,Lopez-Castejon G,Glenn S,Brough D,Andrew PW,Cavet JS,Roberts IS

更新日期：2012-01-01 00:00:00

abstract：:CC chemokine receptor 4 (CCR4) and its two ligands, CCL17 and CCL22, are critically involved in different immune processes. In models of lipopolysaccharide-induced shock, CCR4-deficient (CCR4(-/-)) mice showed improved survival rates associated with attenuated proinflammatory cytokine release. Using CCR4(-/-) mice wit...

journal_title：Infection and immunity

authors： Traeger T,Kessler W,Assfalg V,Cziupka K,Koerner P,Dassow C,Breitbach K,Mikulcak M,Steinmetz I,Pfeffer K,Heidecke CD,Maier S

更新日期：2008-11-01 00:00:00

abstract：:When Streptococcus pyogenes group A type 3 strain C203 (M+) and its M-protein-lacking derivative, strain C203S (M-), were treated with normal human serum in the presence of magnesium-EGTA [ethylene glycol-bis(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid], virulent M+ bacteria bound only 10 to 30% as much C3 and f...

journal_title：Infection and immunity

authors： Hong K,Kinoshita T,Takeda J,Kozono H,Pramoonjago P,Kim YU,Inoue K

更新日期：1990-08-01 00:00:00

abstract：:Representative strains of oral streptococci were tested for Fc immunoglobulin G (IgG) reactivity by two different techniques, agglutination of rabbit-IgG sensitized sheep erythrocytes and uptake of human and rabbit 125I-radiolabeled IgG. None of the S. mutans serotypes a through e reacted with the Fc region of either ...

journal_title：Infection and immunity

authors： Shea C,Ferretti JJ

更新日期：1981-12-01 00:00:00

abstract：:Relapsing fever (RF) is a spirochetal infection characterized by relapses of a febrile illness and spirochetemia due to the sequential appearance and disappearance of isogenic serotypes in the blood. The only difference between isogenic serotypes is the variable major outer membrane lipoprotein. In the absence of spec...

journal_title：Infection and immunity

authors： Sethi N,Sondey M,Bai Y,Kim KS,Cadavid D

更新日期：2006-11-01 00:00:00

abstract：:Antibody to Pseudomonas aeruginosa exotoxin was detected in human sera by using a cytotoxicity-neutralization assay. Serum antitoxin was present in high titer in all 14 patients who recovered from serious pseudomonas infections (log2 of 50% neutralization titer, mean +/- standard deviation = 6.0 +/- 1.2). In contrast,...

journal_title：Infection and immunity

authors： Pollack M,Callahan LT 3rd,Taylor NS

更新日期：1976-10-01 00:00:00

abstract：:Fonsecaea pedrosoi is a fungal pathogen that produces melanin. The functions of melanin and its possible influence in the protective immunological response during infection by F. pedrosoi are not known. In this work, treatment of F. pedrosoi mycelia with proteases and glycosidases followed by a denaturing agent and ho...

journal_title：Infection and immunity

authors： Alviano DS,Franzen AJ,Travassos LR,Holandino C,Rozental S,Ejzemberg R,Alviano CS,Rodrigues ML

更新日期：2004-01-01 00:00:00

abstract：:Intestinal mucus is postulated to play a role in preventing colonization of the gastrointestinal tract by microbial pathogens. To evaluate the ability of both crude mucus and purified mucin, a glycoprotein of goblet cell origin, to inhibit mucosal adherence of enteric pathogens, we examined whether mucus and mucin der...

journal_title：Infection and immunity

authors： Drumm B,Roberton AM,Sherman PM

更新日期：1988-09-01 00:00:00

abstract：:Malaria infection treatment vaccine (ITV) is a promising strategy to induce homologous and heterologous protective immunity against the blood stage of the parasite. However, the underlying mechanism of protection remains largely unknown. Here, we found that a malaria-specific antibody (Ab) could mediate the protective...

journal_title：Infection and immunity

authors： Liu T,Lu X,Zhao C,Fu X,Zhao T,Xu W

更新日期：2015-05-01 00:00:00

abstract：:Proteus mirabilis, a common agent of nosocomially acquired and catheter-associated urinary tract infection, is the most frequent cause of infection-induced bladder and kidney stones. Urease-catalyzed urea hydrolysis initiates stone formation in urine and can be inhibited by acetohydroxamic acid and other structural an...

journal_title：Infection and immunity

authors： Nicholson EB,Concaugh EA,Mobley HL

更新日期：1991-10-01 00:00:00

abstract：:We show here that Helicobacter pylori broth culture supernatants disrupt the actin cytoskeleton of epithelial cell lines, leading to cell rounding and apoptosis through anoikis. We demonstrate that there are marked quantitative differences between strains and that there are different cell line sensitivities. By constr...

journal_title：Infection and immunity

authors： Bebb JR,Letley DP,Rhead JL,Atherton JC

更新日期：2003-06-01 00:00:00

abstract：:An attenuated Salmonella typhi Ty21a vaccine was administered to 18 infants and toddlers (less than or equal to 24 months old) to determine its safety and immunogenicity. The vaccination (10(9) CFU per dose, three doses) was well tolerated. However, after the vaccination there was no evidence of a humoral or cellular ...

journal_title：Infection and immunity

authors： Murphy JR,Grez L,Schlesinger L,Ferreccio C,Baqar S,Muñoz C,Wasserman SS,Losonsky G,Olson JG,Levine MM

更新日期：1991-11-01 00:00:00

abstract：:Of 202 captive hares studied, many of which had lesions on their external genital organs or testicular atrophy or both, 27% had positive serological tests for syphilis although dark-field examination of extracts of atrophic testes was negative. A total of 12 hares that were nonreactive for the serological test for syp...

journal_title：Infection and immunity

authors： Horvath I,Kemenes F,Molnar L,Szeky A,Racz I

更新日期：1980-01-01 00:00:00

abstract：:During a Plasmodium chabaudi infection in interleukin-10 (IL-10) knockout mice, there is greater parasite sequestration, more severe cerebral edema, and a high frequency of cerebral hemorrhage compared with infection of C57BL/6 mice. Anti-tumor necrosis factor alpha treatment ameliorated both cerebral edema and hemorr...

journal_title：Infection and immunity

authors： Sanni LA,Jarra W,Li C,Langhorne J

更新日期：2004-05-01 00:00:00

abstract：:Candida-associated denture stomatitis (DS) is a persistent and chronic oral infection of the denture-bearing palatal mucosa. DS stems from the ability of the fungal opportunistic pathogen Candida albicans to adhere to denture material and invade palatal tissue. Although DS is the most prevalent form of oral candidiasi...

journal_title：Infection and immunity

authors： Sultan AS,Rizk AM,Vila T,Ji Y,Masri R,Jabra-Rizk MA

更新日期：2019-11-18 00:00:00

abstract：:The humoral and cell-mediated immune responses of murine lymphocytes exposed to lead in vivo and in vitro were investigated. In vivo Pb was administered via the drinking water (0 to 10 mM) for 1 to 10 weeks. In vivo exposure of the mice to Pb did not alter significantly their plaque-forming cell response to sheep eryt...

journal_title：Infection and immunity

authors： Lawrence DA

更新日期：1981-01-01 00:00:00

abstract：:The expression of T cell differentiation markers is known to increase during Mycobacterium tuberculosis infection, and yet the biological role of such markers remains unclear. We examined the requirement of the T cell differentiation marker killer cell lectin-like receptor G1 (KLRG1) during M. tuberculosis infection u...

journal_title：Infection and immunity

authors： Cyktor JC,Carruthers B,Stromberg P,Flaño E,Pircher H,Turner J

更新日期：2013-04-01 00:00:00