Inhibition of attachment of Escherichia coli RDEC-1 to intestinal microvillus membranes by rabbit ileal mucus and mucin in vitro.

abstract：:Cholera toxin (CT) is a potent adjuvant for mucosal vaccination; however, its mechanism of action has not been clarified completely. It is well established that peripheral monocytes differentiate into dendritic cells (DCs) both in vitro and in vivo and that monocytes are the in vivo precursors of mucosal CD103(-) proi...

journal_title：Infection and immunity

authors： Veglia F,Sciaraffia E,Riccomi A,Pinto D,Negri DR,De Magistris MT,Vendetti S

更新日期：2011-03-01 00:00:00

abstract：:Lack of efficacious vaccines against Mycobacterium tuberculosis (MTB) infection is a limiting factor in the prevention and control of tuberculosis (TB), the leading cause of death from an infectious agent. Improvement or replacement of the BCG vaccine with one that reliably protects all age-groups is urgent. Concerns ...

journal_title：Infection and immunity

authors： Wang Y,Li Z,Wu S,Fleming J,Li C,Zhu G,Chen B,Ren B,Wang X,Du B,Li P,Hu P,Yang J,Liu Y,Zhou C,Zhang XE,Bi L,Zhang H,Yang J,Zhang Z

更新日期：2020-12-14 00:00:00

abstract：:Both rat alveolar macrophages and a human macrophages cell line with characteristics of human tissue (e.g., alveolar) macrophages (THP-1) were found to inhibit the germination of Rhizopus spores. However, the conditions under which fungistatic activity occurs are different for these two cell types. The inhibition of R...

journal_title：Infection and immunity

authors： Jorens PG,Boelaert JR,Halloy V,Zamora R,Schneider YJ,Herman AG

更新日期：1995-11-01 00:00:00

abstract：:We describe here a Sprague-Dawley rat model for chronic osteomyelitis. Staphylococcus aureus and sodium morrhuate were implanted by either microdrilling or direct needle injection into the tibiae of rats. Of 107 rats, 87 (81%) developed osteomyelitis when a high-speed drill was used for implantation, and 27 (51%) of 5...

journal_title：Infection and immunity

authors： Rissing JP,Buxton TB,Weinstein RS,Shockley RK

更新日期：1985-03-01 00:00:00

abstract：:Tuberculosis remains a leading killer worldwide, and new approaches for its treatment and prevention are urgently needed. This effort will benefit greatly from a better understanding of gene regulation in Mycobacterium tuberculosis, particularly with respect to this pathogen's response to its host environment. We exam...

journal_title：Infection and immunity

authors： Purkayastha A,McCue LA,McDonough KA

更新日期：2002-03-01 00:00:00

abstract：:Epitope mapping of outer surface protein C (OspC) by using sera from patients with neuroborreliosis led to the identification of one single major immunodominant epitope within the C-terminal 10 amino acid residues. Peptide binding studies and alanine replacement scanning of the C-terminal decapeptide, PVVAESPKKP, reve...

journal_title：Infection and immunity

authors： Mathiesen MJ,Holm A,Christiansen M,Blom J,Hansen K,Ostergaard S,Theisen M

更新日期：1998-09-01 00:00:00

abstract：:Peripheral leukocytes from 16 Thai children with dengue hemorrhagic fever were examined to determine the leukocyte composition on the day of presentation and on convalescent days 15 and 30. Mononuclear cells were isolated each time, and the concentrations of T, B, Fc receptor-bearing, and "null" cells were determined....

journal_title：Infection and immunity

authors： Wells RA,Scott RM,Pavanand K,Sathitsathein V,Cheamudon U,Macdermott RP

更新日期：1980-05-01 00:00:00

abstract：:Candida-associated denture stomatitis (DS) is a persistent and chronic oral infection of the denture-bearing palatal mucosa. DS stems from the ability of the fungal opportunistic pathogen Candida albicans to adhere to denture material and invade palatal tissue. Although DS is the most prevalent form of oral candidiasi...

journal_title：Infection and immunity

authors： Sultan AS,Rizk AM,Vila T,Ji Y,Masri R,Jabra-Rizk MA

更新日期：2019-11-18 00:00:00

abstract：:The hallmarks of enteropathogenic Escherichia coli (EPEC) infection are formation of attaching and effacing (A/E) lesions on mucosal surfaces and actin-rich pedestals on cultured cells, both of which are dependent on the type III secretion system effector Tir. Following translocation into cultured cells and clustering...

journal_title：Infection and immunity

authors： Crepin VF,Habibzay M,Glegola-Madejska I,Guenot M,Collins JW,Frankel G

更新日期：2015-09-01 00:00:00

abstract：:Pneumonia due to Gram-negative bacteria is associated with high mortality. Acinetobacter baumannii is a Gram-negative bacterium that is associated with hospital-acquired and ventilator-associated pneumonia. Bacteria have been described to release outer membrane vesicles (OMVs) that are capable of mediating systemic in...

journal_title：Infection and immunity

authors： Marion CR,Lee J,Sharma L,Park KS,Lee C,Liu W,Liu P,Feng J,Gho YS,Dela Cruz CS

更新日期：2019-08-21 00:00:00

abstract：:In evolving to an obligate intracellular niche, Chlamydia has streamlined its genome by eliminating superfluous genes as it relies on the host cell for a variety of nutritional needs like amino acids. However, Chlamydia can experience amino acid starvation when the human host cell in which the bacteria reside is expos...

journal_title：Infection and immunity

authors： Ouellette SP,Rueden KJ,Rucks EA

更新日期：2016-08-19 00:00:00

abstract：:The ethanol-insoluble product formed from sucrose by purified enzyme encoded by the gtfA gene from Streptococcus mutans, expressed in recombinant Escherichia coli, was analyzed by 13C and 31P nuclear magnetic resonance. The product was identified as alpha-D-glucose-1-phosphate, and it was concluded that the GTF-A enzy...

journal_title：Infection and immunity

authors： Russell RR,Mukasa H,Shimamura A,Ferretti JJ

更新日期：1988-10-01 00:00:00

abstract：:In the present investigation we studied the nature of a Shigella flexneri O antigen, the type III antigen. No structural entity has yet been attributed to this antigen. Phenol-water-extracted lipopolysaccharides (LPSs) from all S. flexneri serotypes possessing either group 6 antigen or both type III antigen and group ...

journal_title：Infection and immunity

authors： Carlin NI,Wehler T,Lindberg AA

更新日期：1986-07-01 00:00:00

abstract：:Murine bone marrow-derived macrophages were infected with a panel of virulent isolates of Mycobacterium tuberculosis including laboratory strains Erdman and H37Rv and various clinical isolates in order to determine the sensitivity of each of these strains to the antimycobacterial activities of macrophage-generated rea...

journal_title：Infection and immunity

authors： Rhoades ER,Orme IM

更新日期：1997-04-01 00:00:00

abstract：:Infection of L cells with Chlamydia psittaci inhibited the burst of deoxyribonucleic acid synthesis that occurs when the host cells are released from a double thymidine block. ...

journal_title：Infection and immunity

authors： Tribby II,Moulder JW

更新日期：1971-02-01 00:00:00

abstract：:Isolated outer membranes of Borrelia burgdorferi 297 were utilized to obtain partial amino acid sequence information for a low-molecular-weight, outer membrane-associated polypeptide. Degenerate oligonucleotide primers based upon this information were used to amplify a 100-bp probe for detection of the corresponding f...

journal_title：Infection and immunity

authors： Lahdenne P,Porcella SF,Hagman KE,Akins DR,Popova TG,Cox DL,Katona LI,Radolf JD,Norgard MV

更新日期：1997-02-01 00:00:00

abstract：:The selection of influenza B virus recombinants from plaques in bovine kidney cell monolayers is described. Two sets of recombinants were each derived from parents of high and low virulence for humans, respectively. Recombination frequency was apparently high, and reassortment of genes made it possible to obtain atten...

journal_title：Infection and immunity

authors： Beare AS,Sherwood JE,Callow KA,Craig JW

更新日期：1977-02-01 00:00:00

abstract：:Three dominant proteins (41, 48, and 49 kDa) were detected by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) in purified preparations of the extracellular aspartyl proteinase (AP) of Candida albicans. All three proteins bound to the specific carboxyl proteinase ligand, pepstatin A, and were assoc...

journal_title：Infection and immunity

authors： Morrison CJ,Hurst SF,Bragg SL,Kuykendall RJ,Diaz H,Pohl J,Reiss E

更新日期：1993-05-01 00:00:00

abstract：:Ecto-5'-nucleotidase (CD73) is expressed abundantly on the apical surface of intestinal epithelial cells (IECs) and functions as the terminal enzyme in the generation of extracellular adenosine. Previous work demonstrated that adenosine signaling in IECs results in a number of tissue-protective effects during inflamma...

journal_title：Infection and immunity

authors： Kao DJ,Saeedi BJ,Kitzenberg D,Burney KM,Dobrinskikh E,Battista KD,Vázquez-Torres A,Colgan SP,Kominsky DJ

更新日期：2017-09-20 00:00:00

abstract：:Previous studies have shown that a mutant (designated C4) of Streptococcus mutans 6715 wild type (WT) is defective in glucosyltransferase (GTF)-synthesized insoluble glucan and is avirulent in gnotobiotic rats. This study investigated the factors which would render this mutant virulent in gnotobiotic rats. Microbial a...

journal_title：Infection and immunity

authors： Hirasawa M,Kiyono H,Shiota T,Hull RA,Curtiss R 3rd,Michalek SM,McGhee JR

更新日期：1980-03-01 00:00:00

abstract：:Neisseria gonorrhoeae is generally considered to be an obligate aerobe; it can, however, grow in the absence of oxygen by anaerobic respiration by using nitrite as a terminal electron acceptor. The outer membrane protein compositions of aerobically and anaerobically grown N. gonorrhoeae strains were compared by one- a...

journal_title：Infection and immunity

authors： Clark VL,Campbell LA,Palermo DA,Evans TM,Klimpel KW

更新日期：1987-06-01 00:00:00

abstract：:Phytohemagglutinin is able to trigger interferon synthesis in spleen cell cultures from nude (nu/nu) mice as effectively as in splenic cell cultures from haired, control (nu/+), thymus-bearing mice. A minor theta-bearing cell population present in the spleen of nude mice appears essential to phytohemagglutinin interfe...

journal_title：Infection and immunity

authors： Wietzerbin J,Stefanos S,Falcoff R,Lucero M,Catinot L,Falcoff E

更新日期：1978-09-01 00:00:00

abstract：:Legionella pneumophila is a facultative intracellular bacterium which readily grows in cultures of guinea pig and human mononuclear phagocytes. In this report, we demonstrate that the Legionella sp. also grows in thioglycolate-elicited macrophages obtained from A/J mice but not in cells from other mouse strains tested...

journal_title：Infection and immunity

authors： Yamamoto Y,Klein TW,Newton CA,Widen R,Friedman H

更新日期：1988-02-01 00:00:00

abstract：:Brucella abortus is a class III zoonotic bacterial pathogen able to survive and replicate inside host cells, including macrophages. Here we report a multidimensional transposon sequencing analysis to identify genes essential for Brucella abortus growth in rich medium and replication in RAW 264.7 macrophages. The const...

journal_title：Infection and immunity

authors： Sternon JF,Godessart P,Gonçalves de Freitas R,Van der Henst M,Poncin K,Francis N,Willemart K,Christen M,Christen B,Letesson JJ,De Bolle X

更新日期：2018-07-23 00:00:00

abstract：:This study was undertaken to determine the sequence of events in the microenvironment of the intestinal tract that culminate in the symptoms of cholera and to attempt to define more clearly the mechanisms involved in antibacterial immunity. The extent to which mucus occurs in the normal intestine of rabbits and the ap...

journal_title：Infection and immunity

authors： Schrank GD,Verwey WF

更新日期：1976-01-01 00:00:00

abstract：:A nonhuman primate model for malaria vaccine development allowing reliable, stringent sporozoite challenge and evaluation of both cellular and antibody responses is needed. We therefore constructed a multicomponent, multistage DNA vaccine for the simian malaria species Plasmodium knowlesi including two preerythrocytic...

journal_title：Infection and immunity

authors： Rogers WO,Baird JK,Kumar A,Tine JA,Weiss W,Aguiar JC,Gowda K,Gwadz R,Kumar S,Gold M,Hoffman SL

更新日期：2001-09-01 00:00:00

abstract：:Haemophilus influenzae is a commensal and opportunistic pathogen of the human airways. A number of surface molecules contribute to colonization of the airways by H. influenzae, such as adhesins, including structures found in the lipooligosaccharide (LOS). A human bronchiolar xenograft model was employed to investigate...

journal_title：Infection and immunity

authors： Swords WE,Chance DL,Cohn LA,Shao J,Apicella MA,Smith AL

更新日期：2002-08-01 00:00:00

abstract：:The aroC gene of the facultative intracellular pathogen Brucella suis was cloned and sequenced. The cloned aroC gene complements Escherichia coli and Salmonella enterica serovar Typhimurium aroC mutants. A B. suis aroC mutant was found to be unable to grow in a defined medium without aromatic compounds. The mutant was...

journal_title：Infection and immunity

authors： Foulongne V,Walravens K,Bourg G,Boschiroli ML,Godfroid J,Ramuz M,O'Callaghan D

更新日期：2001-01-01 00:00:00

abstract：:Inbred mouse strains differ in their susceptibility to infection with the facultative intracellular bacterium Listeria monocytogenes, largely due to delayed or deficient innate immune responses. Previous antibody depletion studies suggested that neutrophils (polymorphonuclear leukocytes [PMN]) were particularly import...

journal_title：Infection and immunity

authors： Pitts MG,Combs TA,D'Orazio SEF

更新日期：2018-03-22 00:00:00

abstract：:Alpha-2,3-sialyltransferase (Lst) is expressed on the outer membrane of Neisseria gonorrhoeae and Neisseria meningitidis and sialylates surface lipooligosaccharide (LOS), facilitating resistance to complement-mediated killing. The enzyme is constitutively expressed from a single gene (lst) and does not undergo antigen...

journal_title：Infection and immunity

authors： Packiam M,Shell DM,Liu SV,Liu YB,McGee DJ,Srivastava R,Seal S,Rest RF

更新日期：2006-05-01 00:00:00