Heterogeneity of the purified extracellular aspartyl proteinase from Candida albicans: characterization with monoclonal antibodies and N-terminal amino acid sequence analysis.

abstract：:Onchocerca volvulus, a human parasitic nematode, is the third leading cause of preventable blindness worldwide. This study describes the molecular cloning of a novel superoxide dismutase (SOD) from the parasite. This putative O. volvulus extracellular SOD (OvEcSOD) is 628 nucleotides (nt) long, including a 22-nt 5' sp...

journal_title：Infection and immunity

authors： James ER,McLean DC Jr,Perler F

更新日期：1994-02-01 00:00:00

abstract：:Complement receptor type 3 (CR3) was initially described as an opsonic receptor. Subsequently, CR3-mediated lectin-sugar recognition mechanisms have been shown to play a major role in the nonopsonic phagocytosis of several pathogens, among them Mycobacterium tuberculosis. Little is known about the binding and signal t...

journal_title：Infection and immunity

authors： Le Cabec V,Cols C,Maridonneau-Parini I

更新日期：2000-08-01 00:00:00

abstract：:Hepatitis, proliferative typhlitis, and colitis were characterized in young adult and older SCID/NCr mice naturally infected with Helicobacter hepaticus. Liver lesions consisted of Kupffer, Ito, and oval cell hyperplasia along with multifocal to coalescing coagulative hepatocyte necrosis. Numerous Warthin-Starry-posit...

journal_title：Infection and immunity

authors： Li X,Fox JG,Whary MT,Yan L,Shames B,Zhao Z

更新日期：1998-11-01 00:00:00

abstract：:Yersinia enterocolitica is a human pathogen that is ubiquitous in livestock, especially pigs. The bacteria are able to colonize the intestinal tract of a variety of mammalian hosts, but the severity of induced gut-associated diseases (yersiniosis) differs significantly between hosts. To gain more information about the...

journal_title：Infection and immunity

authors： Schaake J,Kronshage M,Uliczka F,Rohde M,Knuuti T,Strauch E,Fruth A,Wos-Oxley M,Dersch P

更新日期：2013-11-01 00:00:00

abstract：:Three open reading frames (ORFs) were identified by a genome walking strategy in the genomes of serotype M49 group A streptococcal (GAS) strains CS101 and 591. These ORFs were located between the mga core regulon and the dipeptide permease operon. The deduced amino acid (aa) sequences contained signature sequences ind...

journal_title：Infection and immunity

authors： Elsner A,Kreikemeyer B,Braun-Kiewnick A,Spellerberg B,Buttaro BA,Podbielski A

更新日期：2002-09-01 00:00:00

abstract：:Colonization by Bordetella bronchiseptica results in a variety of inflammatory respiratory infections, including canine kennel cough, porcine atrophic rhinitis, and a whooping cough-like disease in humans. For successful colonization, B. bronchiseptica must acquire iron (Fe) from the infected host. A vast amount of Fe...

journal_title：Infection and immunity

authors： Mocny JC,Olson JS,Connell TD

更新日期：2007-10-01 00:00:00

abstract：:We undertook a morphological and immunochemical comparison of purified outer membrane antigens from oral and nonoral isolates of Bacteroides asaccharolyticus. Electron micrographs of thin sections of whole bacteria revealed a compact, electron-dense capsule external to the outer membrane of oral strains. A loose, web-...

journal_title：Infection and immunity

authors： Mansheim BJ,Coleman SE

更新日期：1980-02-01 00:00:00

abstract：:Acquired cellular immunity to infection with Mycobacterium tuberculosis is believed to reside in the capacity of mononuclear phagocytes of immunized animals to inhibit intracellular multiplication of the parasite. However, in macrophage tissue culture systems, it has been customary to employ streptomycin in the medium...

journal_title：Infection and immunity

authors： Patterson RJ,Youmans GP

更新日期：1970-01-01 00:00:00

abstract：:Thirty percent of Streptococcus pneumoniae isolates contain pilus islet 1, coding for a pilus composed of the backbone subunit RrgB and two ancillary proteins, RrgA and RrgC. RrgA is the major determinant of in vitro adhesion associated with pilus 1, is protective in vivo in mouse models, and exists in two variants (c...

journal_title：Infection and immunity

authors： Moschioni M,Emolo C,Biagini M,Maccari S,Pansegrau W,Donati C,Hilleringmann M,Ferlenghi I,Ruggiero P,Sinisi A,Pizza M,Norais N,Barocchi MA,Masignani V

更新日期：2010-12-01 00:00:00

abstract：:Coxiella burnetii, the agent of Q fever, enters human monocytes through alpha(v)beta(3) integrin and survives inside host cells. In addition, C. burnetii stimulates the synthesis of inflammatory cytokines including tumor necrosis factor (TNF) by monocytes. We studied the role of the interaction of C. burnetii with THP...

journal_title：Infection and immunity

authors： Dellacasagrande J,Ghigo E,Hammami SM,Toman R,Raoult D,Capo C,Mege JL

更新日期：2000-10-01 00:00:00

abstract：:Cholera is an acute diarrheal disease that is caused by the gram-negative bacterium Vibrio cholerae. The low efficacy of currently available killed-whole-cell vaccines and the reactinogenicity coupled with potential reversion of live vaccines have thus far precluded widespread vaccination for the control of cholera. R...

journal_title：Infection and immunity

authors： Wu JY,Wade WF,Taylor RK

更新日期：2001-12-01 00:00:00

abstract：:Autoclaving cell wall of Streptococcus mutans Ingbritt for 15 min under the Rantz and Randall conditions released one-tenth of the total cell wall carbohydrate, whereas two-thirds was extracted after autoclaving for 180 min. The extract contained the serotype c-specific antigen but lacked the lipoteichoic acid compone...

journal_title：Infection and immunity

authors： Campbell LK,Knox KW,Wicken AJ

更新日期：1978-12-01 00:00:00

abstract：:Scrub typhus is a potentially lethal infection that is caused by the obligate intracellular bacterium Orientia tsutsugamushi The roles of Toll-like receptor 2 (TLR2) and TLR4 in innate recognition of O. tsutsugamushi have not been elucidated. By overexpression of TLR2 or TLR4 in HEK293 cells, we demonstrated that TLR2...

journal_title：Infection and immunity

authors： Gharaibeh M,Hagedorn M,Lilla S,Hauptmann M,Heine H,Fleischer B,Keller C

更新日期：2016-11-18 00:00:00

abstract：:An acute and persistent eosinophil infiltration is observed during Mycobacterium bovis BCG pleural infection in mice. Eosinophil accumulation, lipid body formation, and eotaxin production were significantly reduced in BCG-infected Toll-like receptor-2 (TLR2)-deficient mice compared to wild-type mice. Neutralization of...

journal_title：Infection and immunity

authors： D'Avila H,Almeida PE,Roque NR,Castro-Faria-Neto HC,Bozza PT

更新日期：2007-03-01 00:00:00

abstract：:We examined the secretion of antimicrobial proteins and peptides into surgically isolated and continuously perfused segments of rat small intestine. Up to nine discrete antimicrobial molecules appeared in the intestinal perfusates following intravenous administration of bethanechol, a cholinergic agonist, or intralume...

journal_title：Infection and immunity

authors： Qu XD,Lloyd KC,Walsh JH,Lehrer RI

更新日期：1996-12-01 00:00:00

abstract：:Inflammatory cytokines play an important role in human immune responses to malarial disease. However, the role of these mediators in disease pathogenesis, and the relationship between host protection and injury remains unclear. A total of 248 cases of severe Plasmodium falciparum malaria among children aged 3 months t...

journal_title：Infection and immunity

authors： Lyke KE,Burges R,Cissoko Y,Sangare L,Dao M,Diarra I,Kone A,Harley R,Plowe CV,Doumbo OK,Sztein MB

更新日期：2004-10-01 00:00:00

abstract：:Mycobacterium tuberculosis grows within the phagocytic vacuoles of macrophages, where it encounters a moderately acidic and possibly nutrient-restricted environment. Other mycobacterial species encounter acidic conditions in soil and aquatic environments. We have evaluated the influence of pH and divalent cation level...

journal_title：Infection and immunity

authors： Piddington DL,Kashkouli A,Buchmeier NA

更新日期：2000-08-01 00:00:00

abstract：:A murine monoclonal antibody was raised against the B95-8 strain of Epstein-Barr virus (EBV), which was isolated from a case of mononucleosis after blood transfusion (Hoffman et al. Proc. Natl. Acad. Sci. U.S.A. 77:2979, 1980). We provide evidence that neutralization of immortalization by this monoclonal antibody is v...

journal_title：Infection and immunity

authors： Miller G,Heston L,Hoffman G

更新日期：1982-09-01 00:00:00

abstract：:Toxoplasma gondii is a ubiquitous parasite that persists for the life of a healthy mammalian host. A latent, chronic infection can reactivate upon immunosuppression and cause life-threatening diseases, such as encephalitis. A key to the pathogenesis is the parasite's interconversion between the tachyzoite (in acute in...

journal_title：Infection and immunity

authors： Kim SK,Karasov A,Boothroyd JC

更新日期：2007-04-01 00:00:00

abstract：:Haemophilus influenzae is a commensal and opportunistic pathogen of the human airways. A number of surface molecules contribute to colonization of the airways by H. influenzae, such as adhesins, including structures found in the lipooligosaccharide (LOS). A human bronchiolar xenograft model was employed to investigate...

journal_title：Infection and immunity

authors： Swords WE,Chance DL,Cohn LA,Shao J,Apicella MA,Smith AL

更新日期：2002-08-01 00:00:00

abstract：:Bovine NK cells have recently been characterized and the present study describes the interaction between NK cells, antigen-presenting cells, and secreted mycobacterial proteins. Gamma interferon (IFN-gamma) production by NK cells was seen in approximately 30% of noninfected calves in response to the Mycobacterium tube...

journal_title：Infection and immunity

authors： Olsen I,Boysen P,Kulberg S,Hope JC,Jungersen G,Storset AK

更新日期：2005-09-01 00:00:00

abstract：:The nonacylated form of protein D (PDm) of Haemophilus influenzae has been shown to induce the production of antibodies that are bactericidal to homologous and heterologous nontypeable H. influenzae (NTHi) strains. In this study, immunization of rats with lipoprotein D (LPD) induced higher levels of anti-protein D imm...

journal_title：Infection and immunity

authors： Akkoyunlu M,Melhus A,Capiau C,van Opstal O,Forsgren A

更新日期：1997-12-01 00:00:00

abstract：:Streptococcus iniae causes meningoencephalitis and death in commercial fish species and has recently been identified as an emerging human pathogen producing fulminant soft tissue infection. As identified by pulsed-field gel electrophoresis (PFGE), strains causing disease in either fish or humans belong to a single clo...

journal_title：Infection and immunity

authors： Fuller JD,Bast DJ,Nizet V,Low DE,de Azavedo JC

更新日期：2001-04-01 00:00:00

abstract：:Anti-NMDA receptor (NMDAR) autoantibodies have been postulated to play a role in the pathogenesis of NMDAR hypofunction, which contributes to the etiology of psychotic symptoms. Toxoplasma gondii is a pathogen implicated in psychiatric disorders and associated with elevation of NMDAR autoantibodies. However, it remain...

journal_title：Infection and immunity

authors： Li Y,Viscidi RP,Kannan G,McFarland R,Pletnikov MV,Severance EG,Yolken RH,Xiao J

更新日期：2018-09-21 00:00:00

abstract：:L-phase variants and small colony (G-phase) variants derived from penicillinase-producing Staphylococcus aureus strains were tested for penicillinase (beta lactamase) production. A refined variation of the modified Gots test for penicillinase was used to demonstrate penicillinase synthesis. Penicillinase synthesis was...

journal_title：Infection and immunity

authors： Simon HJ,Yin EJ

更新日期：1970-11-01 00:00:00

abstract：:Formation of compact colonies of Staphylococcus aureus in serum-soft agar is mainly a result of a reaction between protein A and the Fc-part of immunoglobulin G and not a clumping factor-fibrinogen reaction. ...

journal_title：Infection and immunity

authors： Forsum U,Forsgren A,Hjelm E

更新日期：1972-10-01 00:00:00

abstract：:Streptococcus pneumoniae is a major pathogen in humans. The pathogenicity of this organism is related to its many virulence factors, the most important of which is the thick pneumococcal capsule that minimizes phagocytosis. Another virulence-associated trait is the tendency of this bacterium to undergo autolysis in st...

journal_title：Infection and immunity

authors： Martner A,Skovbjerg S,Paton JC,Wold AE

更新日期：2009-09-01 00:00:00

abstract：:Improvement of antibody responses to polysaccharides through their linkage to proteins is thought to be mediated by protein-specific T helper (Th) cells. To investigate whether the carrier protein of a conjugate could be substituted by a Th epitope, Streptococcus pneumoniae type 17F polysaccharide (PS) was bromoacetyl...

journal_title：Infection and immunity

authors： de Velasco EA,Merkus D,Anderton S,Verheul AF,Lizzio EF,Van der Zee R,Van Eden W,Hoffman T,Verhoef J,Snippe H

更新日期：1995-03-01 00:00:00

abstract：:Hamster trachea organ cultres were shown to consume measurable amounts of oxygen when incubated in a closed micro-chamber. Several simple and complex media were evaluated, and the optimal system involved incubating 2 to 4 mg of tracheal tissue in Tyrodes balanced salt solution at 37 C for 60 min, with oxygen activity ...

journal_title：Infection and immunity

authors： Gabridge MG

更新日期：1975-09-01 00:00:00

abstract：:Because combined administration of intramuscular and intravenous interferon has been partially successful in the incubationary treatment of rabies, the effect of direct interferon administration into the cerebrospinal fluid space was tested. After injecting 1,800 U of interferon into the cisterna magna or the lateral ...

journal_title：Infection and immunity

authors： Ho M,Nash C,Morgan CW,Armstrong JA,Carroll RG,Postic B

更新日期：1974-02-01 00:00:00