Stereospecific interaction of bicuculline with specific [3H]strychnine binding to rat spinal cord synaptosomal membranes.

abstract：:Attention deficit hyperactivity disorder (ADHD) is a developmental disorder characterized by inattentiveness, motor hyperactivity and impulsivity. According to neuroimaging data, the neural substrate underlying ADHD seems to involve fronto-striatal circuits and the cerebellum. However, there are important discrepancie...

journal_title：Neuroscience letters

authors： Carmona S,Vilarroya O,Bielsa A,Trèmols V,Soliva JC,Rovira M,Tomàs J,Raheb C,Gispert JD,Batlle S,Bulbena A

更新日期：2005-12-02 00:00:00

abstract：:Total RNA was purified from rat forebrain at different postnatal ages and analyzed by Northern blot using a specific neurotensin receptor RNA probe. The rat neurotensin receptor mRNA was present in high amount during the first 10 days of life. Thereafter, it rapidly decreased and was undetected after 20 days. [3H]neur...

journal_title：Neuroscience letters

authors： Hermans E,Jeanjean AP,Laduron PM,Octave JN,Maloteaux JM

更新日期：1993-07-09 00:00:00

abstract：:The effect of chronic alcoholism in the neuronal nuclear area (karyometry) of the lateral entorhinal cortex at three rostro-caudal levels (rostral, intermediate and caudal) has been studied in 19 alcoholic subjects and in 15 aged-matched controls. Cases were distributed into three groups according to their age (29-44,...

journal_title：Neuroscience letters

authors： Ibáñez J,Herrero MT,Insausti R,Belzunegui T,Tuñón T,García-Bragado F,Gonzalo LM

更新日期：1995-01-02 00:00:00

abstract：:The effects of various Flustra foliacea metabolites on different types of human neuronal nicotinic acetylcholine receptors (nAChRs) expressed in Xenopus oocytes were investigated. Whereas most of the compounds tested had a small blocking effect, one of them, deformylflustrabromine, selectively increased the current ob...

journal_title：Neuroscience letters

authors： Sala F,Mulet J,Reddy KP,Bernal JA,Wikman P,Valor LM,Peters L,König GM,Criado M,Sala S

更新日期：2005-01-10 00:00:00

abstract：:The cloned vanilloid receptor-1 (VR1) is recognized as a common molecular target for protons, noxious heat, and vanilloids. The presence of VR1 in the dorsal root, trigeminal, and nodose ganglia has been firmly established, but it is unclear in the gut, despite this VR1 may be important for gastric mucosal homeostasis...

journal_title：Neuroscience letters

authors： Nozawa Y,Nishihara K,Yamamoto A,Nakano M,Ajioka H,Matsuura N

更新日期：2001-08-17 00:00:00

abstract：:The influence of transient forebrain ischemia on the temporal alteration of NMDA receptor (NMDAR1) mRNAs in the hippocampal formation was analysed by in situ hybridization, RNA blot and in vitro receptor autoradiography ([3H]3-((+)2-carboxypiperazin-4-yl)-propyl-1- phosphonic acid). In the CA1 subfield of the hippocam...

journal_title：Neuroscience letters

authors： Sugimoto A,Takeda A,Kogure K,Onodera H

更新日期：1994-03-28 00:00:00

abstract：:Nitric oxide (NO) exerts cytotoxic effects on various cells including neuronal cells. Glial NO production, mediated via induction of inducible NO synthase (iNOS), enhances neurotoxicity associated with the N-methyl-D-aspartate (NMDA) receptor. The present study examined whether nicotinamide, an inhibitor of poly (ADP-...

journal_title：Neuroscience letters

authors： Fujimura M,Tominaga T,Yoshimoto T

更新日期：1997-06-06 00:00:00

abstract：:Magnetic resonance imaging (MRI) of two pig brains was realized. The animals were placed in the stereotaxic conditions currently used in experiments. To allow the positioning of the animal in the MRI instrument, landmarks were previously traced on the snout of the pig. To avoid movements, animals were deeply anestheti...

journal_title：Neuroscience letters

authors： Marcilloux JC,Félix MB,Rampin O,Stoffels C,Ibazizen MT,Cabanis EA,Laplace JP,Albe-Fessard D

更新日期：1993-06-25 00:00:00

abstract：:The neurotoxicity of the glutamate receptor agonists N-methyl-D-aspartate (NMDA), (+/-)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA), and kainate was quantitatively assessed in murine spinal cord and cortical cultures prepared under identical conditions. Compared with cortical neurons, spinal neuron...

journal_title：Neuroscience letters

authors： Regan RF

更新日期：1996-07-26 00:00:00

abstract：:In the rat the response of suprachiasmatic nucleus neurons to steady retinal illumination at different adaptation luminances was studied. The results confirm that in this nucleus the discharge rate is more commonly increased than suppressed by light. Interval histograms indicate that a complex process underlies the di...

journal_title：Neuroscience letters

authors： Groos G,Mason R

更新日期：1978-04-01 00:00:00

abstract：:The depression of the amplitude of extracellularly recorded monosynaptic excitatory field potentials in the lumbar spinal cord of pentobarbitone anaesthetised rats and cats by three thienyl derivatives of GABA: 4-amino-3-(2-thienyl)-butanoic acid; 4-amino-3-(2-thienyl-5-methyl)-butanoic acid and 4-amino-3-(2-thienyl-5...

journal_title：Neuroscience letters

authors： Lacey G,Berthelot P,Vaccher C,Flouquet N,Vaccher MP,Debaert M,Curtis DR

更新日期：1993-09-03 00:00:00

abstract：:Oestrogen influences both oxytocin mRNA and peptide immunoreactivity in the preoptic area and the rat oxytocin gene contains functional oestrogen response elements. However, using combinations of immunocytochemistry and in situ hybridization for oxytocin and oestrogen receptor, we found that preoptic oxytocin neurons ...

journal_title：Neuroscience letters

authors： Cruttwell CJ,Herbison AE,Bicknell RJ

更新日期：1995-11-17 00:00:00

abstract：:The effect of the neuropeptide, substance P, on the transport of D-[(3)H]aspartate into rat striatal synaptosomes was studied. Almost 90% of the total transport of D-[(3)H]aspartate was sodium-dependent and the maximum rate (V(max)) of this transport was increased by 34% of control by 2.5 nM substance P (EC(50)=0.52 n...

journal_title：Neuroscience letters

authors： Healy J,Downes A,McBean GJ

更新日期：2000-08-25 00:00:00

abstract：:Non-photic stimuli, such as diurnal wheel running in rodents, phase shift the circadian clock and suppress the expression of Per1 in the suprachiasmatic nucleus (SCN). The goal of the present study was to directly decrease Per1 expression using antisense (AS) oligodeoxynucleotides to determine if such suppression prod...

journal_title：Neuroscience letters

authors： Hamada T,Antle MC,Silver R

更新日期：2004-05-20 00:00:00

abstract：:The presence and distribution of the presumed pan-neural marker protein gene product 9.5 (PGP)- and peptide-immunoreactive (ir) nerve fibers in alveolar walls of various species was investigated by light microscopic single and double staining immunohistochemistry. PGP-, tachykinin (TK)-, and calcitonin gene-related pe...

journal_title：Neuroscience letters

authors： Nohr D,Weihe E

更新日期：1991-12-16 00:00:00

abstract：:This study examined the ERP (event-related potential) correlates of categorization processing in brand extension with irrelative task. Participants faced two sequential stimuli in a pair consisting of a soft drink brand name (S1) and a product name (S2) which comprised two categories: beverage (typical product of the ...

journal_title：Neuroscience letters

authors： Wang X,Ma Q,Wang C

更新日期：2012-09-06 00:00:00

abstract：:Damage to sub-cortical white matter is a key substrate of vascular dementia (VaD) leading to deficits in executive function and cognitive processing speed. Dynamin1 is a 100 kDa protein, accounting for 0.4% of the total brain protein, and has a central role in many intracellular processes such as synaptic vesicle traf...

journal_title：Neuroscience letters

authors： Mulugeta E,Vallortigara J,Francis PT,Hye A,Kalaria RN,Perry EK,Lovestone S,Ballard CG

更新日期：2014-03-20 00:00:00

abstract：:We investigated the effects of a representative anti-epileptic or anti-psychotic drug, carbamazepine (CBZ), on the induction of long-term potentiation (LTP) in the perforant path-dentate gyrus pathway in 15 chronically prepared rabbits. Pharmacokinetically injected low-dose CBZ, which produced steady serum levels of 2...

journal_title：Neuroscience letters

authors： Kubota T,Jibiki I,Fukushima T,Kurokawa K,Yamaguchi N

更新日期：1994-03-28 00:00:00

abstract：:The effects of maternal deprivation (MD) during early postnatal life on the brain-derived neurotrophic factor (BDNF) level were investigated in the present study. Wistar rats were assigned to either maternal deprivation or mother-reared control (MRC) groups. MD manipulation was achieved by separating rat pups from the...

journal_title：Neuroscience letters

authors： Kuma H,Miki T,Matsumoto Y,Gu H,Li HP,Kusaka T,Satriotomo I,Okamoto H,Yokoyama T,Bedi KS,Onishi S,Suwaki H,Takeuchi Y

更新日期：2004-11-30 00:00:00

abstract：:The facial nucleus (FN) has been known as a motor nucleus to control the activity of the facial skeletal muscles by its efferent somatic motoneurons. Much less, however, is known about the non-motor control functions of its interneurons. The present study was designed to investigate if the interneurons of the FN parti...

journal_title：Neuroscience letters

authors： Zhang C,Yan H,Li C,Zheng Y

更新日期：2004-09-09 00:00:00

abstract：:Hippocampal norepinephrine (NE) is secreted by neurons projecting from the locus coeruleus (LC) to the hippocampus; LC nicotinic receptors (NAchRs) are involved in the effects of systemic nicotine on this pathway. To clarify the NAchR subtypes, NAchR antagonists, termed alpha-conotoxins, were microinjected into the LC...

journal_title：Neuroscience letters

authors： Fu Y,Matta SG,McIntosh JM,Sharp BM

更新日期：1999-05-07 00:00:00

abstract：:Long-term potentiation (LTP) of perforant-path dentate granule cell synapses, in awake rats, was followed by a time-dependent expression of brain-derived neurotrophic factor (BDNF) mRNA in dentate granule cells. This BDNF expression was blocked by the N-methyl-D-aspartate (NMDA) antagonist dizocilpine maleate (MK-801)...

journal_title：Neuroscience letters

authors： Dragunow M,Beilharz E,Mason B,Lawlor P,Abraham W,Gluckman P

更新日期：1993-10-01 00:00:00

abstract：:Fatigue of the lumbar extensor muscles has been associated with a degradation of balance, but the mechanism is not well understood. The ankle plays a major role in upright standing, and loss of proprioceptive acuity at the ankle could contribute to a degradation of balance. Therefore, the first objective of this study...

journal_title：Neuroscience letters

authors： Pline KM,Madigan ML,Nussbaum MA,Grange RW

更新日期：2005-12-16 00:00:00

abstract：:The present study has employed in vitro autoradiography to study the distribution and density of [3H]zolpidem binding sites, which are regarded as an index of ethanol-sensitive gamma-aminobutyric acid (GABA)A receptors, in the brains of alcohol-preferring Fawn-Hooded (FH) rats compared to non-alcohol preferring Wistar...

journal_title：Neuroscience letters

authors： Chen F,Rezvani A,Jarrott B,Lawrence AJ

更新日期：1997-12-05 00:00:00

abstract：BACKGROUND:Studies have demonstrated that the failure of oligodendrocyte precursor cells (OPCs) differentiation as a major cause of remyelination failure in demyelinating disease. The reasons for this failure are not completely understood. We hypothesized that the present of myelin debris in CNS play an important role ...

journal_title：Neuroscience letters

authors： Liu Q,Lv HW,Yang S,He YQ,Ma QR,Liu J

更新日期：2020-04-23 00:00:00

abstract：:The role of descending monoaminergic systems in the antinociceptive effect of kyotorphin (Tyr-Arg, KTP) was investigated in mice by means of the tail-pinch test. We compared this effect with that of the delta-opioid receptor agonist [D-Pen(2,5)]-enkephalin (DPDPE). The antinociceptive effect of KTP and DPDPE injected ...

journal_title：Neuroscience letters

authors： Ochi T,Ohkubo Y,Mutoh S

更新日期：2002-08-30 00:00:00

abstract：:Previous studies have suggested that motor cortex may be involved in complex control of respiration in man. In this study, we estimated the influence of a simple visuomotor reaction time task (VMT) on the inspiratory airflow curve (IFC) by comparing measurements of standard deviation (SD), C(0) complexity and approxim...

journal_title：Neuroscience letters

authors： Zhang T,Turner D

更新日期：2001-01-05 00:00:00

abstract：:Several studies reported that peripheral administration of bombesin (BN) and gastrin-releasing peptide (GRP) improved some forms of memory performance. In the present study, we examined the role of endogenous BN-like peptide(s) for the acquisition of inhibitory avoidance learning in mice using BN-like peptide receptor...

journal_title：Neuroscience letters

authors： Santo-Yamada Y,Yamada K,Wada E,Goto Y,Wada K

更新日期：2003-04-03 00:00:00

abstract：:gamma-Aminobutyric acid (GABA) is the major inhibitory transmitter in the mammalian central nervous system (CNS) and an understanding of the development of receptors for this compound is of considerable interest. In this study, 3 monoclonal antibodies directed against the GABAA/benzodiazepine (GABA/BDZ) receptor were ...

journal_title：Neuroscience letters

authors： Ventimiglia R,Grierson JP,Gallombardo P,Sweetnam PM,Tallman JF,Geller HM

更新日期：1990-07-31 00:00:00

abstract：:Calcitonin gene-related peptide (CGRP) immunoreactive afferent nerves were seen intrarenally by prenatal day 16. They grow rapidly and CGRP positive nerves are observed at birth associated with the arterial and venous vascular tree, forming a rich plexus in the pelvic region and in the connective tissue located near t...

journal_title：Neuroscience letters

authors： Barajas L,Liu L,Nishiyama C

更新日期：1991-12-09 00:00:00