Mutations to spectinomycin resistance which alleviate the restriction of an amber suppressor by streptomycin resistance.

Abstract:

:Unlike mutations to streptomycin resistance, which restrict the function of an SU II amber suppressor, mutations to spectinomycin resistance have no restrictive effect. Furthermore, mutations to spectinomycin resistance counteract the restrictive action of streptomycin-resistant mutations when combined in a single strain. The mutations to drug resistance, singly or in combination, do not themselves lead to any detectable suppressor activity. The effects on SU II are interpreted in terms of interactions between ribosomal elements.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Kuwano M,Endo H,Ohnishi Y

doi

10.1128/JB.97.2.940-943.1969

subject

Has Abstract

pub_date

1969-02-01 00:00:00

pages

940-3

issue

2

eissn

0021-9193

issn

1098-5530

journal_volume

97

pub_type

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