Abstract:
:In the bovine ovary there is a delay of 4-6 days between the observed maximum of oxytocin mRNA and the peak in the luteal levels of oxytocin nonapeptide. This implies a maturation process involving components of the post-translational processing pathway. In situ hybridization shows the oxytocin gene to be transcribed exclusively in the large cells of the corpus luteum at the beginning of the estrous cycle.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Fehr S,Ivell R,Koll R,Schams D,Fields M,Richter Ddoi
10.1016/0014-5793(87)81295-4subject
Has Abstractpub_date
1987-01-01 00:00:00pages
45-50issue
1eissn
0014-5793issn
1873-3468pii
0014-5793(87)81295-4journal_volume
210pub_type
杂志文章相关文献
FEBS LETTERS文献大全abstract::The functional characteristics of rat organic anion transporter OAT1 were investigated using Xenopus laevis oocytes. Uptake of p-aminohippurate (PAH) by the oocytes expressing OAT1 was markedly inhibited by glutarate, alpha-ketoglutarate and probenecid, moderately inhibited by folate and methotrexate, but not inhibite...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/s0014-5793(98)01328-3
更新日期:1998-11-06 00:00:00
abstract::The 40 N-terminal amino acids of the 20 kDa antigen A2 from Brucella melitensis were sequenced and showed important similarities with 4 bacterioferrins. A monoclonal antibody raised against this antigen cross-reacted with Escherichia coli bacterioferritin. Hybridization of two sets of degenerate primers with B. melite...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/0014-5793(95)00189-g
更新日期:1995-03-20 00:00:00
abstract::Mouse interferon (alpha + beta) given to mice by intraperitoneal injection suppressed both the accumulation of putrescine and stimulation of DNA synthesis in liver caused by partial hepatectomy. The suppression of DNA synthesis was completely reversed by exogenous putrescine. The same results were obtained when core 2...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/0014-5793(86)80866-3
更新日期:1986-09-01 00:00:00
abstract::The critical urea concentration (C3*) which destabilizes the structure of bovine serum albumin and chymotrypsinogen was determined by UV difference spectroscopy. The increase of the relative content of mobile rotating water molecules in aqueous urea was formerly shown by millimeter spectroscopy [1]. The rise of rotato...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/0014-5793(93)81152-p
更新日期:1993-01-04 00:00:00
abstract::The effects of nine drugs on the CD spectra of a synthetic calcium binding analog of site III of rabbit skeletal troponin C, can generally be divided into 3 groups: (1) that consisting of haloperidol, benperidol, molindone and promethazine, had no effect on the CD spectrum or calcium sensitivity of the apopeptide; (2)...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/0014-5793(83)80875-8
更新日期:1983-04-05 00:00:00
abstract::Comparison of the phosphotyrosine-specific dephosphorylation of the autophosphorylated receptors for epidermal growth factor (EGF) and platelet-derived growth factor (PDGF) in Swiss 3T3 cell membranes by the endogenous phosphatases revealed striking differences. EGF receptor dephosphorylation was clearly faster than P...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/0014-5793(93)80352-u
更新日期:1993-10-04 00:00:00
abstract::Part of the cytoplasmic domain of a human desmoglein, Dsg1, a cadherin-like protein found in desmosomes of epithelial cells, has been visualised by electron microscopy. The cloned fragment contains five repeats of a 29 +/- 4 residue sequence unique to desmogleins, followed by a glycine-rich region. In rotary shadowed ...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/0014-5793(94)01049-8
更新日期:1994-10-17 00:00:00
abstract::The secretion mechanisms of cathepsin L from osteoclasts in the process of bone resorption were investigated. The increases in bone pit numbers formed take place by PTH addition in parallel with the increases of cathepsin L and/or L-like proteinase activities in the culture medium of bone cells, and these were suppres...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/0014-5793(94)80522-9
更新日期:1994-04-11 00:00:00
abstract::We characterized the promoter activity of a medaka fish intestinal guanylyl cyclase gene, OlGC6, by assay of enzyme activity in response to various promoter-luciferase fusion gene constructs introduced into CACO-2 cells and medaka fish embryos. A transient transfection assay of the various fusion gene constructs showe...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/s0014-5793(03)00002-4
更新日期:2003-02-11 00:00:00
abstract::We examined the role of p38 mitogen-activated protein (MAP) kinase in the tumor necrosis factor alpha (TNF-alpha)- or interleukin-1beta (IL-1beta)-induced production of interleukin-6 (IL-6) and interleukin-8 (IL-8) in fresh rheumatoid synovial fibroblast (RSF) cultures concomitantly with the induction of p38 MAP kinas...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/s0014-5793(99)01717-2
更新日期:2000-01-07 00:00:00
abstract::In aqueous suspensions of purple membranes (pH 10.2, 0.4 M KCl) an intermediate having an absorption maximum at 570-575 nm (at -196 degrees C) was produced by first heating the M intermediate up to -30 degrees C and then stabilizing it by subsequent cooling to -60 degrees C. We suggest that this species is the interme...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/0014-5793(90)80380-2
更新日期:1990-10-01 00:00:00
abstract::A gene encoding an antifreeze protein (AFP) was isolated from carrot (Daucus carota) using sequence information derived from the purified protein. The carrot AFP is highly similar to the polygalacturonase inhibitor protein (PGIP) family of apoplastic plant leucine-rich repeat (LRR) proteins. Expression of the AFP gene...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/s0014-5793(99)00280-x
更新日期:1999-03-26 00:00:00
abstract::Cytosolic extracts of trout and turkey erythrocytes were tested for their immunoreactivity with polyclonal and monoclonal antibodies to retinal arrestin (S-antigen), a cytosolic protein of photoreceptor cells involved in the desensitization of rhodopsin. After adsorption or immunoaffinity chromatography of the extract...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/0014-5793(89)81663-1
更新日期:1989-12-04 00:00:00
abstract::The fluorescence intensity of the Ca2+,Mg2(+)-ATPase protein of rabbit skeletal sarcoplasmic reticulum that incorporated about 2 mol of 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole (NBD-Cl) was enhanced at high MgATP concentrations with or without 50 microM calcium. The observed enhancement indicates that the fluorophore, ...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/0014-5793(90)80021-a
更新日期:1990-01-01 00:00:00
abstract::Clusters of codons pairing to low-abundance tRNAs synchronize the translation with co-translational folding of single domains in multidomain proteins. Although proven with some examples, the impact of the ribosomal speed on the folding and solubility on a global, cell-wide level remains elusive. Here we show that upre...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/j.febslet.2012.07.012
更新日期:2012-09-21 00:00:00
abstract::We recently reported that production of reactive oxygen species (ROS) is essential for auxin-induced gravitropic signaling. Here, we investigated the role of phosphatidylinositol 3-kinase and its product, PtdIns(3)P, in auxin-mediated ROS production and the root gravitropic response. Pretreatment with LY294002, an inh...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/j.febslet.2005.01.018
更新日期:2005-02-14 00:00:00
abstract::Autophagy is a bulk degradation process conserved among eukaryotes. In macro-autophagy, autophagosomes sequester cytoplasmic components and deliver their contents to lysosomes/vacuoles. Autophagosome formation requires the conjugation of Atg8, a ubiquitin-like protein, to phosphatidylethanolamine (PE). Here we report ...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/j.febslet.2009.03.009
更新日期:2009-04-02 00:00:00
abstract::MicroRNA (miRNA) play a pivotal role in the development of liver fibrosis. However, the functions of miRNA in hepatitis C virus (HCV)-related liver fibrosis remain unclear. In this study, we systematically analyzed the microarray data of the serum miRNA in patients with HCV-induced hepatic fibrosis. Among 41 dysregula...
journal_title:FEBS letters
pub_type: 信件
doi:10.1002/1873-3468.12309
更新日期:2016-08-01 00:00:00
abstract::Mutations of the cysteines (positions 668 and 714) were generated in the IF2 C domain of Bacillus stearothermophilus translation initiation factor IF2. The corresponding proteins were characterized functionally and structurally. Most (yet not all) amino acid replacements at both positions resulted in severe reduction ...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/s0014-5793(99)01280-6
更新日期:1999-10-15 00:00:00
abstract::We identified a CpG island at the 5' end of murine leukemia inhibitory factor gene (LIF). The CpG island is 0.6 kb long and covers most of the first exon and first intron. The region is non-methylated, its G+C content is 65% and relative frequency of CpG dinucleotide is 0.7. The block of 150 nucleotides, which is 72% ...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/0014-5793(93)80058-3
更新日期:1993-03-15 00:00:00
abstract::The complete sequence of a 94 amino acid human seminal plasma polypeptide exhibiting inhibin-like activity is presented. This molecule, called beta-inhibin, selectively and specifically suppresses the release of pituitary FSH in vivo as well as in vitro. It does not affect the secretion of LH. Such a novel acidic prot...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/0014-5793(84)80766-8
更新日期:1984-10-01 00:00:00
abstract::The Escherichia coli signal transduction protein PII, product of the glnB gene, was overproduced and purified. The predicted molecular weight of the protein based on the correct nucleotide sequence is 12,427 and is very close to the value 12,435 obtained by matrix-assisted laser desorption mass spectrometry. Hexagonal...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/0014-5793(94)80203-3
更新日期:1994-01-17 00:00:00
abstract::Bisdioxopiperazine anti-cancer agents are catalytic inhibitors of topoisomerase II which by unknown means lock the enzyme in a closed clamp form and inhibit its ATPase activity. In order to demarcate a putative pharmacophore, we here describe a novel Tyr165Ser mutation in the enzyme's Walker A ATP binding site leading...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/s0014-5793(02)02805-3
更新日期:2002-06-05 00:00:00
abstract::The bcl-2 gene is an important antagonist of apoptosis, the programmed cell death. Bcl-2 is highly expressed in a variety of lymphomas. Lymphocytes of patients with chronic lymphocytic leukemia (CLL) express high amounts of bcl-2 even in the absence of the t(14;18) translocation, resulting in a strong resistance towar...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/s0014-5793(97)00229-9
更新日期:1997-04-07 00:00:00
abstract::A sensitive and specific radioimmunoassay suitable for direct measurement of leukotriene C4 was developed. Acetylated leukotriene C4 was coupled to polyamino bovine serum albumin using 1-ethyl-3-(3-dimethylamino-propyl) carbodiimide hydrochloride as coupling agent. The conjugate in complete or incomplete Freund's adju...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/0014-5793(83)80487-6
更新日期:1983-02-07 00:00:00
abstract::The small GTPase Rho1 plays an essential role in controlling the organization of the actin cytoskeleton and synthesis of the cell wall in the fission yeast Schizosaccharomyces pombe. Here we studied the role of Rho5 whose primary structure is very similar to that of Rho1. It was found that elevated expression of Rho5 ...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/j.febslet.2005.08.031
更新日期:2005-09-26 00:00:00
abstract::Cripto-1 and OCT4, expressed in stem cells and cancers, play important roles in tumorigenesis. Here, we demonstrate that Cripto-1 expression is regulated by OCT4 in human embryonic carcinoma NCCIT cells. The endogenous expression of Cripto-1 and OCT4 is significantly reduced during differentiation. Cripto-1 expression...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1002/1873-3468.12935
更新日期:2018-01-01 00:00:00
abstract::Anomalously high values of photoinduced absorption changes were revealed in the antenna of photosynthetic purple bacteria. They were found to be 4-16 times greater at the bleaching peak of the antenna than at the bleaching peak of the BChl dimer of the reaction center. This is direct proof of excitation delocalization...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/0014-5793(95)00663-t
更新日期:1995-07-17 00:00:00
abstract::Carbohydrate chains of C1-inhibitor were identified with a binding assay using different lectins. Lectins from Sambucus nigra (SNA) and Maackia amurensis (MAA) that are specific for sialic acids bound to C1-inhibitor. Lectin from Datura stramonium (DSA) reacted also with the inhibitor indicating complex and hybrid sug...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/0014-5793(92)81520-v
更新日期:1992-12-21 00:00:00
abstract::HGTD-P is a hypoxia-responsive pro-apoptotic protein that transmits hypoxic signals directly to mitochondria. When overexpressed, HGTD-P induces cell death via typical mitochondrial apoptotic cascades. However, much is unknown about post-transcriptional modification and signaling networks of HGTD-P in association with...
journal_title:FEBS letters
pub_type: 杂志文章
doi:10.1016/j.febslet.2006.05.001
更新日期:2006-05-29 00:00:00