Abstract:
:Structural differences between platelet and endothelial cell thrombospondin (TBSP) were found in two protease-resistant domains (70 and 18 kDa). The 70 kDa fragment is involved in the binding of TBSP to fibrinogen and the 18 kDa fragment in the attachment to various cultured cells. Despite these structural differences, platelet and endothelial cell TBSP bound with the same affinity to fibrinogen and mediated the attachment of smooth muscle cells but not of endothelial cells.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Clezardin P,Bourdillon MC,Hunter NR,McGregor JLdoi
10.1016/0014-5793(88)80001-2subject
Has Abstractpub_date
1988-02-15 00:00:00pages
215-8issue
2eissn
0014-5793issn
1873-3468pii
0014-5793(88)80001-2journal_volume
228pub_type
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