Abstract:
:A 569 bp probe against the beta-chain of hepatotropin was used to examine expression of RNA for this growth factor in human adult and foetal liver, foetal kidney and pancreas, and rat liver after partial hepatectomy. Low level expression of a 6 kb RNA occurred in human adult and normal rat liver. 70% hepatectomy increased expression, peaking at 10 h and returning to near normal levels 24 h after resection. The 6 kb band was strongly expressed in human foetal liver, as compared with adult, but not in foetal kidney or pancreas, suggesting a major role for hepatotropin in both foetal development and regeneration of the liver.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Selden C,Jones M,Wade D,Hodgson Hdoi
10.1016/0014-5793(90)81239-ksubject
Has Abstractpub_date
1990-09-17 00:00:00pages
81-4issue
1-2eissn
0014-5793issn
1873-3468pii
0014-5793(90)81239-Kjournal_volume
270pub_type
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