Abstract:
Background:Undernutrition is a common childhood problem in India which may contribute to higher risk of infection and lower survival rate in children with acute lymphoblastic leukemia (ALL). Methods:In our study, we retrospectively included patients of age group 1-15 years who were treated for ALL and survived induction. Data on weight, height and serum albumin levels recorded at the time of diagnosis of the patients were used in this study. For defining acute undernutrition we used weight-for-height, weight-for-age criteria for children ≤5 years and body mass index for age >5 years. We correlated nutritional status of the patients with severe infection and mortality percentage. Results:There were 101 patients with male:female ratio of 2.4:1. Forty-four children were ≤5 years and 57 children were >5 years of age. It was found that 74 children had B-cell ALL and 17 children had T-cell ALL; 54 patients were stratified as high-risk and 47 as standard-risk. In all, 52.5% patients had acute undernutrition at diagnosis. In ALL patients with acute undernutrition, severe infection was found to be 10.8% higher than ALL patients with normal nutrition which was statistically insignificant. Male children and children with serum albumin level <3.5 g/dL in the acute undernutrition group had higher risk of infection. Mortality percentage of patients with baseline acute undernutrition was found to be higher by 11% than normal nutrition group (P-value = 0.21). Conclusion:Our study highlights the magnitude of undernutrition at diagnosis in ALL patients in a tertiary care centre. It also correlates nutritional status with severe infection and mortality in follow-up.
journal_name
Indian J Cancerjournal_title
Indian journal of cancerauthors
Sonowal R,Gupta Vdoi
10.4103/ijc.IJC_110_19subject
Has Abstractpub_date
2021-01-06 00:00:00eissn
0019-509Xissn
1998-4774pii
297011pub_type
杂志文章abstract:BACKGROUND:Non-urothelial bladder tumors (NUBTs) are uncommon accounting for approximately 10% of the total urinary bladder tumors while 90% are urothelial in origin. There are very limited comprehensive studies on NUBTs. AIMS AND OBJECTIVES:The objectives of the study were to analyze the clinicopathological and immun...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_459_17
更新日期:2019-07-01 00:00:00
abstract::Twenty-two histologically confirmed cases of Clear Cell Sarcomas (C.C.S.) seen over a sixteen year period, are retrospectively analysed from a clinico-pathological view-point. The tumours occurred in young adults, average 36 years. Males predominated, and the lower extremity particularly the thigh and foot were the mo...
journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:
更新日期:1989-09-01 00:00:00
abstract:CONTEXT:Use of neoadjuvant chemotherapy (NACT) in locally advanced breast cancer (LABC) enables tumor reduction and conservative surgery. It is proposed in some studies that there may be an alteration in the hormonal receptor (HR) status and human epidermal growth factor receptor 2 (Her-2)/neu immune-expression followi...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.200669
更新日期:2016-07-01 00:00:00
abstract::Serum levels of Lactate Dehydrogenase (LDH), alpha-Hydroxybutyrate Dehydrogenase (HBDH) and the relative ratio of alpha-Hydroxybutyrate Dehydrogenase to Lactate Dehydrogenase (HBDH/LDH) were determined in 51 cases of histologically proved testicular germ cell tumors and 40 healthy controls. Serum LDH and HBDH levels w...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1990-12-01 00:00:00
abstract:BACKGROUND:Ovarian tumors are uncommon in childhood and constitute around 1% of childhood malignancies. Two thirds of pediatric ovarian tumors are germ cell tumors. Epithelial ovarian tumors and stromal tumors are less frequent. We share our experience in childhood ovarian cancers, analyzing a series of cases with resp...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.197726
更新日期:2016-04-01 00:00:00
abstract::The ultimate progress in the cancer diagnosis and therapy has only been possible with the ongoing translational research that is likely to play a very important role in future as well. Hence the importance of such translation from bedside to bench and vis versa cannot be over-emphasized. Accordingly it has become more...
journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:10.4103/0019-509x.31163
更新日期:2007-01-01 00:00:00
abstract::Positron emission tomography (PET) has emerged as an important diagnostic tool in the management of lung cancers. Although PET is sensitive in detection of lung cancer, but FDG (2-deoxy-2- 18 fluro-D-glucose) is not tumor specific and may accumulate in a variety of nonmalignant conditions occasionally giving false pos...
journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:10.4103/0019-509x.44660
更新日期:2008-10-01 00:00:00
abstract::Background: The aim of this study was to investigate the association of head and neck squamous cell carcinoma (HNSCC) with serum levels of interleukin-7 (IL-7) and IL-8, the two cytokines whose associations with HNSCC need more clarifications. Materials and Methods: Commercial enzyme-linked immunosorbent assay kits we...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.146728
更新日期:2014-07-01 00:00:00
abstract::A case report of a squamous cell carcinoma arising in a dermoid cyst of the ovary in a 29 year old patient is presented. Such an occurrence in young patients is unusual. ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:2002-06-01 00:00:00
abstract::Lymphnode infarction is seen in two sets of situations viz. spontaneous banal infarction of non-neoplastic nodes, and in association with lymphoma. It needs to be differentiated from other causes of lymphnode as a phenomenon occurring synchronous with and occasionally preceding diagnosis of lymphoma is significant. ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1989-12-01 00:00:00
abstract::Scrambler therapy (ST) is a novel noninvasive modality for treatment of chronic neuropathic and cancer pain using 5 artificial neurons. The principle with Scrambler Therapy is that synthetic "non-pain" information is transmitted by C fiber surface receptors. Chemotherapy-induced peripheral neuropathy can markedly dete...
journal_title:Indian journal of cancer
pub_type:
doi:10.4103/ijc.IJC_361_18
更新日期:2020-01-01 00:00:00
abstract::Background: Cervical cancer being a major cause of morbidity and mortality in women in developing countries, its awareness is essential. Aim: The aim of this study is to assess the knowledge, attitude and practices of women regarding the basic screening test for detection of cancer cervix. Settings and Design: Populat...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.146780
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND:Lymphedema following breast cancer treatment is one of the most morbid conditions affecting breast cancer survivors. Currently, no therapy completely cures this condition. Comprehensive Decongestive Therapy (CDT), a novel physiotherapeutic method offers promising results in managing this condition. This ther...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.92250
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a well-known adverse effect of vincristine (VCR). Literature suggests that Asians are predisposed to develop SIADH following VCR administration. However, data regarding the occurrence of SIADH in children with malignancy are limited. This st...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_737_18
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:Tamoxifen is being used in patients with estrogen receptor positive breast cancer as an adjuvant or palliative hormonal therapy. w0 estern studies have found a 30% incidence of gallstones in patients who are taking Tamoxifen and they have proved a significant association between the two. OBJECTIVES:The obje...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509x.49154
更新日期:2009-04-01 00:00:00
abstract::L-asparaginase is a valuable chemotherapeutic agent used in the induction of remission and improvement of long term survival in patients with acute lymphoblastic leukemia. Hyperglycemia is a well known side effect of L-asparaginase. Fourteen patients developed hyperglycemia during induction therapy of acute lymphoblas...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1993-06-01 00:00:00
abstract:BACKGROUND:Incidence of rectal cancer has wide geographical variation. Disease pattern in developing countries is different from developed countries as majority of the patients present in advanced stage because of delayed referral and lack of uniform treatment practices. AIMS:Present study describes the patient profil...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:2004-07-01 00:00:00
abstract::Histopathological findings in 57 surgical specimens of T3 and T4 buccal mucosa cancers are reviewed. The incidence of the well-differentiated tumours (including verrucous carcinoma) was 61%. A moderate degree of lymphocytic infiltration of the tumour was present in 37% of patients. Histologically proven cervical lymph...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1993-12-01 00:00:00
abstract:OBJECTIVE:This study aimed to evaluate the outcome of benign vocal cord tumors treated using a laryngeal endoscopy under low temperature-controlled radiofrequency and to elucidate the application of a dynamic laryngoendoscopy in the operation. MATERIALS AND METHODS:85 patients with benign vocal cord tumors were treate...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.151994
更新日期:2015-02-01 00:00:00
abstract:AIM OF STUDY:To investigate the trend of expression of liver function test enzymes and other biochemical changes during gallbladder carcinogenesis. MATERIALS AND METHODS:Eight hundred and seventy-eight gallbladder disease patients were selected to study the liver function test enzymes and routine blood biochemical cha...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.98938
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:Due to the low sensitivity of Pap smear, premalignant lesions of the cervix can be missed in women with inflammatory Pap smears. However, it is not practically possible to subject all women with inflammatory Pap smear to colposcopy. This study was carried out with the aim to evaluate whether women with persis...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.82901
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:Plumbagin (5-hydroxy-2-methyl-1,4-napthoquinone) derived from Plumbago species is a potential anti-tumour agent. Plumbagin has been tested for anti-cancer activity in vitro and in vivo using mice model. AIM:To study the tumour suppressing efficacy of plumbagin using zebrafish model. MATERIALS AND METHODS:H...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.219580
更新日期:2017-01-01 00:00:00
abstract::Cervical cancer is the leading malignancy among Indian women. It has been estimated that in the absence of any control programme, the incident number of cervical cancer cases in the country would rise to 140 thousand by the turn of this century. Cytology screening remains the main stay for the control of cervix cancer...
journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:
更新日期:1999-06-01 00:00:00
abstract:CONTEXT:Regional epidemiological data regarding the epidermal growth factor receptor (EGFR) mutation status in non-small-cell lung cancers (NSCLC) is an unmet need from the eastern part of India. AIMS:To report the incidence of EGFR mutation and its correlation with the phenotypical characteristics, in NSCLC patients ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_239_17
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Metaplastic breast carcinoma (MBC) is a rare disease with incidence of less than 1%. MBC present with a larger tumor size, less number of nodes involved, mostly undifferentiated triple negative tumors. We aimed to determine progression-free and overall survival and reported hospital-based incidence of MBC. ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_731_18
更新日期:2019-04-01 00:00:00
abstract::Six patients of primary lymphoma of breast are presented. All our patients were female with median age of 46 years. Combination chemotherapy was the mainstay of treatment in all the patients. Five patients achieved complete remission of which two relapsed, one had a distant relapse and the other was local. Patient wit...
journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:
更新日期:1992-09-01 00:00:00
abstract::Resistance to 1st or 2nd generation epidermal growth factor receptor (EGFR) - tyrosine kinases (TKIs) develops predominantly due to an acquired mutation, EGFR T790M. Third-generation EGFR-TKIs have demonstrated potent activity against TKI resistance mediated by EGFR T790M. Thus, it become critical to identify T790M mu...
journal_title:Indian journal of cancer
pub_type:
doi:10.4103/ijc.IJC_545_17
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Wilms' tumor 1 (WT1) mutation has recently been detected in gliomas. Growing data indicate that WT1 mutation plays a causal role in gliomagenesis and is overexpressed in most glioblastomas. An emerging immunotherapy targeting WT1 has shown to be effective in resistant glioblastomas in clinical trials. WT1 ex...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/ijc.IJC_51_18
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Lymphoma combined with hepatitis B infection occupies a relatively higher incidence in China than that of in Europe and America. AIMS:To observe the efficacy and safety of rituximab in combination with chemotherapy in patients with B-cell non-Hodgkin's lymphoma (NHL) and hepatitis B virus (HBV) infection. ...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.200679
更新日期:2016-07-01 00:00:00
abstract:INTRODUCTION:Despite lower incidence of breast cancer in India, the total number of cases and the net mortality is high. To reduce this increasing load of mortality due to breast cancer we need to lay emphasis on early detection and increased use of systemic therapy. Early detection itself depends on early presentation...
journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:10.4103/0019-509X.175602
更新日期:2015-01-01 00:00:00