Abstract：
:Background: The aim of this study was to investigate the association of head and neck squamous cell carcinoma (HNSCC) with serum levels of interleukin-7 (IL-7) and IL-8, the two cytokines whose associations with HNSCC need more clarifications. Materials and Methods: Commercial enzyme-linked immunosorbent assay kits were used for the quantification of the cytokines. Sera were collected from 48 untreated patients (36 men and 12 women; mean age: 52.7 ± 9.8 years) and 34 healthy donors (26 men and 8 women; mean age: 53.1 ± 9.0 years). Results: Serum IL-8 level was neither significantly different between HNSCC patients and control individuals nor associated with smoking status, gender, age, tumor location, tumor grade, and stage of the patients (P > 0.05). Regarding IL-7, all control individuals had serum levels below the sensitivity of the kit (3 pg/ml), but nine patients had detectable levels, and that the mean serum IL-7 was significantly higher in the patients compared to the controls (P = 0.008). Conclusions: Serum IL-8 level is not significantly associated with HNSCC. With the sensitivity of the kit we employed, it seems that serum IL-7 levels are specifically elevated in HNSCC patients compared to healthy individuals. Data from other independent studies are required to clarify the possible employment of IL-7 as an HNSCC biomarker.
journal_name
Indian J Cancerjournal_title
Indian journal of cancerauthors
Mojtahedi Z,Khademi B,Erfani N,Taregh Y,Rafati Z,Malekzadeh M,Ghaderi Adoi
10.4103/0019-509X.146728subject
Has Abstractpub_date
2014-07-01 00:00:00pages
227-230issue
3eissn
0019-509Xissn
1998-4774pii
IndianJournalofCancer_2014_51_3_227_146728journal_volume
51pub_type
杂志文章abstract：:Colloid cyst is a rare benign intracranial neoplasm, commonly located in the third ventricle. Though headache and visual symptoms are classical, the patients may present with sudden neurological deterioration. We present a ten-year-old male child who presented with sudden neurological deterioration due to colloid cyst...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
abstract：AIM:The clinical significance of Fas and FasL in hormone-sensitive carcinomas has been reported. Our objective was to evaluate the expression of apoptosis-regulating genes Fas and FasL in Indian breast cancer and fibroadenoma patients in relation to hormone receptor status. STUDY DESIGN:Retrospective. MATERIALS AND M...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.98921
更新日期：2012-01-01 00:00:00
abstract：:A novel mutation in the MLH1 gene likely to be pathogenic for Lynch syndrome was discovered in a proband with a family history of colon cancer. Immunohistochemistry showed negative expression of PMS2 and MLH1 in the resected tumor sample. The mutation lies at the highly conserved C-terminus of the MLH1 protein, the re...
journal_title：Indian journal of cancer
pub_type：
doi：10.4103/ijc.IJC_349_18
更新日期：2018-10-01 00:00:00
abstract：:A primary testicular tumour in a 62 year old man was found to be a plasmacytoma on histopathological examination without any extra testicular disease prior to or subsequent to orchiectomy, fulfilling the criteria for the primary extramedullary plasmacytoma. Such cases are extremely rare. Evaluation of such a case was ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1998-12-01 00:00:00
abstract：:Cytogenetic analysis using G-banding techniques for the diagnosis of malignancy in pleural and peritoneal effusions is compared with the results of traditional cytomorphology. The studies indicate that the yield of mitotic cells in malignant effusions is quite high when compared to fluids with no cytological evidence ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1989-06-01 00:00:00
abstract：BACKGROUND:Renal cancer is one of the common malignant tumors of the urinary system, seriously threatening human being's health. The current discoveries, however, are far enough for efficient and secure treatment of renal cancer. AIMS:The aim was to explore the mechanism of matrix metalloproteinase-7 (MMP-7) protein i...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.180835
更新日期：2016-01-01 00:00:00
abstract：CONTEXT:Malnutrition is prevalent in children with cancer at diagnosis, especially in low- and middle-income countries (LMIC) where the great majority of children live. It is associated with an added burden of morbidity and mortality. AIMS:Answers were sought to the best measure of nutritional status in LMIC, the impa...
journal_title：Indian journal of cancer
pub_type： 杂志文章,评审
doi：10.4103/0019-509X.175827
更新日期：2015-04-01 00:00:00
abstract：PURPOSE:The aim was to evaluate the safety, feasibility and efficacy of computed tomography (CT)-guided percutaneous interstitial brachytherapy using radioactive iodine-125 ( 125 I) seeds for the treatment of lung cancer. MATERIALS AND METHODS:Included in this study were 45 male and 35 female patients aged 52-85 years...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.151999
更新日期：2015-02-01 00:00:00
abstract：CONTEXT:Tumor budding (TBud) is recognized as a poor prognostic marker in colorectal cancer (CRC) with important treatment implications in Stage II cancers and malignant polyps. There are multiple propositions for bud count reporting but without an uniformly accepted system. The International TBud consensus conference ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/ijc.IJC_642_17
更新日期：2017-10-01 00:00:00
abstract：:Resistance to 1st or 2nd generation epidermal growth factor receptor (EGFR) - tyrosine kinases (TKIs) develops predominantly due to an acquired mutation, EGFR T790M. Third-generation EGFR-TKIs have demonstrated potent activity against TKI resistance mediated by EGFR T790M. Thus, it become critical to identify T790M mu...
journal_title：Indian journal of cancer
pub_type：
doi：10.4103/ijc.IJC_545_17
更新日期：2017-12-01 00:00:00
abstract：:A composite tumour of the caecum and colon, comprising of distinct areas of classical carcinoid and of well differentiated adenocarcinoma is described. Both components were histochemically confirmed. Presence of a morphologic transition at junctional areas favour a histogenesis from bi-directional differentiation of m...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1994-09-01 00:00:00
abstract：:In most parts of the world, tobacco is used for smoking, whereas, in India, tobacco is used for smoking as well as in diverse smokeless forms. Absorption of toxic and carcinogenic chemicals in tobacco and other ingredients added to various products are causally associated with several non-communicable diseases includi...
journal_title：Indian journal of cancer
pub_type： 杂志文章,评审
doi：10.4103/0019-509X.107735
更新日期：2012-10-01 00:00:00
abstract：:Since 1987, 560 patients have been treated in our department for carcinoma of thyroid with radioactive Iodine-131. Recently, we have come across a patient with bilateral pulmonary concentration of Iodine-131, that is visualised on Iodine-131 whole body scintiscan, whereas chest radiogram was negative. Respectively, th...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：2001-06-01 00:00:00
abstract：:Positron emission tomography (PET) has emerged as an important diagnostic tool in the management of lung cancers. Although PET is sensitive in detection of lung cancer, but FDG (2-deoxy-2- 18 fluro-D-glucose) is not tumor specific and may accumulate in a variety of nonmalignant conditions occasionally giving false pos...
journal_title：Indian journal of cancer
pub_type： 杂志文章,评审
doi：10.4103/0019-509x.44660
更新日期：2008-10-01 00:00:00
abstract：BACKGROUND:A relatively new development in the arena of prostatic histopathological study is the premalignant proliferative changes in the glandular epithelium, possibly relating to carcinoma. Two major categories have come up, namely prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia (AAH)....
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：2004-04-01 00:00:00
abstract：:Over the past few decades, considerable success has been achieved in the field of cancer treatment with biological response modifiers (BRM), which are agents that improve the body's ability to fight cancer by immunostimulation. Biological agents, such as interferons and interleukins, provide nonspecific active immunit...
journal_title：Indian journal of cancer
pub_type： 杂志文章,评审
doi：10.4103/0019-509X.73559
更新日期：2010-10-01 00:00:00
abstract：BACKGROUND:The Ewing sarcoma family of tumors (ESFT) are aggressive malignant tumors with small round cell morphology affecting mainly children and adolescents. The aim of this study is to classify the histological diversity and clinical characteristics of ESFT in children from a Tertiary Care Center in South India. M...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.176700
更新日期：2015-07-01 00:00:00
abstract：BACKGROUND:Chronic myeloid leukemia (CML), is the first malignancy that related to the chromosomal abnormality and include 15-20% of all adulthood leukemia. AIMS:This study aimed to compare the hematologic, breakpoint cluster region-abelson (BCR-ABL) and liver function enzymes changes during treatment period of Imatin...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509X.176715
更新日期：2015-07-01 00:00:00
abstract：Background:Despite the advances in screening during the past decades, colorectal cancer (CRC) still is a leading cause of cancer deaths worldwide. Therefore, the development of new diagnostic methods is necessary. Aim:The aim of this study was to compare methylation changes of SRY-Box 21 (SOX21) gene promoter in tumor...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/ijc.IJC_542_18
更新日期：2020-04-01 00:00:00
abstract：:A rare morphological variant of acute lymphoblastic leukaemia in a ten years old child is described. Ninety five percent of the lymphoblasts had significant number of course granules in the cytoplasm. Diagnostic and prognostic significance of this variant is discussed. ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：:Five cases of primary lymphoma of the brain are reported and the literature reviewed. The diverse clinical spectrum at presentation and variable response to therapy are few of its unique features. The literature is reviewed briefly and the importance of diagnosis at an early stage and prompt institution of therapy in ...
journal_title：Indian journal of cancer
pub_type： 杂志文章,评审
doi：
更新日期：1991-06-01 00:00:00
abstract：BACKGROUND:Breast cancer is now the most common cancer in many parts of India and the incidence varies from 12 to 31/100,000, and is rising. Locally advanced breast cancer (LABC) accounts for 30-35% of all cases of breast cancers in India. LABC continues to present a challenge and imposes a major health impact in our c...
journal_title：Indian journal of cancer
pub_type： 临床试验,杂志文章
doi：10.4103/0019-509X.75838
更新日期：2011-01-01 00:00:00
abstract：:It is important to differentiate non-dyplastic aplastic anaemia from hypocellular myelodysplastic syndrome (MDS). Four patients presenting with hypocellular bone marrow and different evolution patterns are being described. Certain morphological features and variable hypocellularity were found to be useful indices for ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1995-09-01 00:00:00
abstract：BACKGROUND:Metaplastic breast carcinoma (MBC) is a rare disease with incidence of less than 1%. MBC present with a larger tumor size, less number of nodes involved, mostly undifferentiated triple negative tumors. We aimed to determine progression-free and overall survival and reported hospital-based incidence of MBC. ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/ijc.IJC_731_18
更新日期：2019-04-01 00:00:00
abstract：:Ketoconazole, an imidazole derivative is known to decrease adrenal steroid biosynthesis by inhibiting cytochrome P450 dependent adrenal enzymes. Three patients of adrenal carcinoma treated with ketoconazole, 600-1200 mg daily showed significant fall in plasma and urinary cortisol levels, but no reduction in tumor size...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1991-12-01 00:00:00
abstract：:This report documents the occurrence of an extragonadal malignant teratoma on the sole of the foot, in a young male. The patient also developed a groin nodule showing the same histology. The testes, retroperitoneum and mediastinum, which are usual sites of germ cell tumours were all normal, and no other primary could ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1992-06-01 00:00:00
abstract：:Gliomatosis peritonei (GP), a rare condition related to ovarian teratomas, is characterized by miliary implants of mature glial tissues on the peritoneum or omentum. We report herein a case of mature teratoma of the ovary with GP with imaging features and pathological correlation. ...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/0019-509x.17064
更新日期：2005-07-01 00:00:00
abstract：BACKGROUND:Recently published prospective clinical trials and two meta-analyses have shown that addition of induction chemotherapy (IC) to concurrent chemoradiation (CRT) could potentially improve outcomes in comparison to CRT alone, in locoregionally advanced nasopharyngeal carcinoma (LANPC). Although it remains uncle...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：10.4103/ijc.IJC_115_18
更新日期：2018-07-01 00:00:00
abstract：:Casual Interpretation of results in a given article has several pitfalls. In order to assess the strengths and limitations of a given article several factors need to be considered. This review article is intended to list, classify and describe briefly the factors that should be considered in the evaluation of an artic...
journal_title：Indian journal of cancer
pub_type： 杂志文章,评审
doi：
更新日期：1999-06-01 00:00:00
abstract：:We have studied fibrinolytic activity of 12 cases of infiltrating duct carcinoma of breast (7 metastatic and 5 non-metastatic) and ten cases of adenocarcinoma of gastrointestinal tract (5 each of metastatic and nonmetastatic), and compared with some of their normal tissue counterparts. Both metastatic and non-metastat...
journal_title：Indian journal of cancer
pub_type： 杂志文章
doi：
更新日期：1991-12-01 00:00:00
