Serum lactate dehydrogenase, alpha-hydroxybutyrate dehydrogenase and ratio of alpha-hydroxybutyrate dehydrogenase to lactate dehydrogenase in testicular tumours.

Abstract:

:Serum levels of Lactate Dehydrogenase (LDH), alpha-Hydroxybutyrate Dehydrogenase (HBDH) and the relative ratio of alpha-Hydroxybutyrate Dehydrogenase to Lactate Dehydrogenase (HBDH/LDH) were determined in 51 cases of histologically proved testicular germ cell tumors and 40 healthy controls. Serum LDH and HBDH levels were found to be raised in both seminomatous and non-seminomatous germ cell tumors. The ratio of HBDH/LDH was found to be statistically significant in seminomas and insignificant in non-seminomatous germ cell tumors. Furthermore, the levels of LDH and HBDH showed a fall, following treatment indicating response to therapy. Serum LDH and HBDH could both be used as tumor markers in the diagnosis of testicular germ cell tumors as well as prognostic indicators in monitoring therapy, HBDH, being more specific in monitoring therapy as compared to serum LDH.

journal_name

Indian J Cancer

journal_title

Indian journal of cancer

authors

Khanolkar MM,Sirsat AV,Deshmane VH,Kamat MR

subject

Has Abstract

pub_date

1990-12-01 00:00:00

pages

243-9

issue

4

eissn

0019-509X

issn

1998-4774

journal_volume

27

pub_type

杂志文章
  • Gastric outlet obstruction and cutaneous metastasis in adenocarcinoid tumor of stomach - unusual presentations with cytologic and ultra structural findings.

    abstract::Neuroendocrine tumors, including carcinoids account for less than 1% of gastric tumors. Various subtypes of gastric carcinoids have been reported earlier. The present case deals with two unusual presentations, diagnosis and course of a gastric neuroendocrine tumor in an adult patient. A 35-years-old male initially pre...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/0019-509x.16700

    authors: Rekhi B,Saxena S,Chintamani.

    更新日期:2005-04-01 00:00:00

  • Hemangiopericytoma of bone--a case report.

    abstract::A case of low grade hemangiopericytoma of three years duration occurring in the upper end of the femur of a 70 year old man is described. Radiologically, the upper third of the right femur showed a destructive expansile osteolytic lesion with soft tissue extension. The tumour was partially encapsulated. Mitoses were 0...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:

    authors: Rao CR,Naresh KN,Pattabhiraman V,Prabhakaran PS,Hazarika D

    更新日期:1994-12-01 00:00:00

  • Proteomics analysis of human brain glial cell proteome by 2D gel.

    abstract:INTRODUCTION:Proteomics is increasingly employed in both neurological and oncological research, and applied widely in every area of neuroscience research including brain cancer. Astrocytomas are the most common glioma and can occur in most parts of the brain and occasionally in the spinal cord. Patients with high-grade...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/0019-509X.138271

    authors: Pooladi M,Abad SK,Hashemi M

    更新日期:2014-04-01 00:00:00

  • Scope and extent of participation of female volunteers in tobacco control activities in Kerala, India.

    abstract:BACKGROUND:In India, NGOs play a key role in creating a supportive environment for the control of tobacco consumption. AIMS:This study was conducted to assess the scope and the extent to which community-based women organizations are involved in tobacco control activities. To assess the scope and extent of participatio...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/0019-509X.63868

    authors: Sreedharan J,Muttapppallymyalil J,Divakaran B

    更新日期:2010-07-01 00:00:00

  • Secondhand smoke in public places: can Bangalore metropolitan transport corporation be a role model for effective implementation of Cigarette and Other Tobacco Products Act, 2003?

    abstract:BACKGROUND:The Indian government enacted 'The cigarettes and other tobacco products act, 2003' (COTPA), which prohibits smoking in public places. AIM:To validate the efficacy of the Act of 2003, enacted by the Government of India, to prevent secondhand smoking in public places. SETTINGS AND DESIGN:The study is based ...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/0019-509X.65316

    authors: Nayak NS,Annigeri VB,Revankar DR,Kenchaigol S

    更新日期:2010-07-01 00:00:00

  • High potential of SOX21 gene promoter methylation as an epigenetic biomarker for early detection of colorectal cancer.

    abstract:Background:Despite the advances in screening during the past decades, colorectal cancer (CRC) still is a leading cause of cancer deaths worldwide. Therefore, the development of new diagnostic methods is necessary. Aim:The aim of this study was to compare methylation changes of SRY-Box 21 (SOX21) gene promoter in tumor...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/ijc.IJC_542_18

    authors: Moradi K,Babaei E,Rezvani N,Safaralizadeh R,Bashiri H,Feizi MAH

    更新日期:2020-04-01 00:00:00

  • Association of gastric cancer incidence with MDR1 gene polymorphism in an ethnic Iranian population.

    abstract:BACKGROUND:The allele frequency of the multidrug resistance 1 (MDR1) gene C3435T polymorphism differs with different ethnic populations, such as Asian, African, and Caucasian. This polymorphism has been reported to be associated with the increase of gastric cancer. OBJECTIVES:The objective of this study was to find ou...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/0019-509X.64723

    authors: Sabahi Z,Salek R,Heravi RE,Mosaffa F,Avanaki ZJ,Behravan J

    更新日期:2010-07-01 00:00:00

  • Damage to the anterior visual pathway and brain parenchyma following external pituitary irradiation.

    abstract::Three cases of damage to the optic nerves and chiasma following pituitary irradiation with Co60 teletherapy are described. All of them presented with progressive visual impairment months following irradiation and simulated recurrence of the tumour. CT scan was also not helpful in differentiating radionecrosis from tum...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:

    authors: Kundra SN,Sharma BS,Banerjee AK,Ayyagari S,Dhir SP,Kak VK

    更新日期:1990-09-01 00:00:00

  • Hepatocellular carcinoma metastatic to bones (Case report with review of literature).

    abstract::A seventy year old man presented with bone pains. Investigation revealed a metastatic bone lesion in the humerus. The primary was found in the liver. The patient achieved good palliation with chemotherapy and radiotherapy and survived for one year. ...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Doval DC,Rao CR,Acharya R,Reddy BK,Bapsy PP

    更新日期:1995-03-01 00:00:00

  • Artificial pneumothorax for pain relief during microwave ablation of subpleural lung tumors.

    abstract:BACKGROUND:When microwave ablation (MWA) is used for subpleural lesions, severe pain was the common side effect under the local anesthesia conditions during the procedure and postprocedure. To study the pain relief effect of artificial pneumothorax in the treatment of subpleural lung tumors with MWA. MATERIALS AND MET...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/0019-509X.172519

    authors: Yang X,Zhang K,Ye X,Zheng A,Huang G,Li W,Wei Z,Wang J,Han X,Ni X,Meng M,Ni Y,Yuan Q,Xing C

    更新日期:2015-12-01 00:00:00

  • Applicability of RNA interference in cancer therapy: Current status.

    abstract::Cancer is a manifestation of dysregulated gene function arising from a complex interplay of oncogenes and tumor suppressor genes present in our body. Cancer has been constantly chased using various therapies but all in vain as most of them are highly effective only in the early stages of cancer. Recently, RNA interfer...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章,评审

    doi:10.4103/0019-509X.175598

    authors: Maduri S

    更新日期:2015-01-01 00:00:00

  • Primary gastrointestinal non Hodgkin's lymphoma chemotherapy alone an effective treatment modality: experience from a single centre in India.

    abstract:BACKGROUND:Gastrointestinal tract (GI) is the most frequently involved extra nodal site in non-Hodgkin's lymphoma (NHL). Surgery, radiotherapy and chemotherapy (CT) have been used mostly in various combinations, but lately chemotherapy alone has emerged as an effective option. The purpose of this study is to evaluate e...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/0019-509x.25773

    authors: Raina V,Sharma A,Vora A,Shukla NK,Deo SV,Dawar R

    更新日期:2006-01-01 00:00:00

  • Outcome of combined modality treatment including neoadjuvant chemotherapy of 128 cases of locally advanced breast cancer: data from a tertiary cancer center in northern India.

    abstract:BACKGROUND:Breast cancer is now the most common cancer in many parts of India and the incidence varies from 12 to 31/100,000, and is rising. Locally advanced breast cancer (LABC) accounts for 30-35% of all cases of breast cancers in India. LABC continues to present a challenge and imposes a major health impact in our c...

    journal_title:Indian journal of cancer

    pub_type: 临床试验,杂志文章

    doi:10.4103/0019-509X.75838

    authors: Raina V,Kunjahari M,Shukla NK,Deo SV,Sharma A,Mohanti BK,Sharma DN

    更新日期:2011-01-01 00:00:00

  • Selective internal radiation therapy: 90Y (yttrium) labeled microspheres for liver malignancies (primary and metastatic).

    abstract::Selective Internal Radiation Therapy is a relatively new technique that irradiates malignant liver lesions using microscopic beads. It provides micro-embolization coupled with high-dose interstitial radiotherapy. Besides colorectal cancers, this therapy has shown benefit in patients with a variety of other tumors incl...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章,评审

    doi:10.4103/0019-509X.76625

    authors: Uthappa MC,Ravikumar R,Gupta A

    更新日期:2011-01-01 00:00:00

  • Central mucoepidermoid carcinoma--a case report.

    abstract::The mucoepidermoid carcinoma (MEC) account for approximately 6-8 Percent of all salivary gland tumors. Central mucoepidermoid carcinoma of the jaws is rare. Following is a case report of central mucoepidermoid carcinoma which involves the ramus of the mandible. Origin of the central mucoepidermoid carcinoma is discuss...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:

    authors: Patil S,Suvarna P,Dayal PK

    更新日期:2000-06-01 00:00:00

  • Palliative weekly chemotherapy along with cetuximab in recurrent and metastatic head and neck cancers: a retrospective analysis.

    abstract:BACKGROUND:This study was undertaken to report the results of weekly combination chemotherapy with cetuximab in recurrent/metastatic head and neck squamous cell carcinoma (R/M SCCHN). MATERIALS AND METHODS:Retrospective analysis of 35 R/M SCCHN patients who received cetuximab with weekly paclitaxel and platin (cisplat...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/0019-509X.98906

    authors: Rangaraju RR,Sharma JB,Dewan AK,Anand AK,Sheh R,Jena A,Chaturvedi AK

    更新日期:2012-01-01 00:00:00

  • Surgical morbidities and outcomes of major salivary gland neoplasms treated at a tertiary cancer center.

    abstract:Background and Objectives:Salivary gland neoplasms are relatively uncommon. They have a wide variety of histopathological types with diverse biological behavior. It involves all the major and minor salivary glands in the head and neck. This article focuses on the various types of major salivary gland tumors treated at ...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/ijc.IJC_466_17

    authors: Thiagarajan S,Fathehi K,Nair D,Deshmukh A,Pantvaidya G,Chaukar DA,D'Cruz AK

    更新日期:2018-01-01 00:00:00

  • V. R. Khanolkar and the Indian Cancer Research Centre, 1952-1962.

    abstract::This note presents a brief account of the ideas and efforts of V.R. Khanolkar in the period 1952-1962 to develop the Indian Cancer Research Centre into a "center of excellence". Khanolkar, who is recognized as a pioneer in cancer research in India, focused on developing multidisciplinary medical research and mentored ...

    journal_title:Indian journal of cancer

    pub_type: 传,历史文章,杂志文章

    doi:10.4103/ijc.IJC_14_19

    authors: Kavadi SN

    更新日期:2019-10-01 00:00:00

  • Hematologic, liver enzymes and electrolytes changes in chronic myeloid leukemia after Imatinib medication.

    abstract:BACKGROUND:Chronic myeloid leukemia (CML), is the first malignancy that related to the chromosomal abnormality and include 15-20% of all adulthood leukemia. AIMS:This study aimed to compare the hematologic, breakpoint cluster region-abelson (BCR-ABL) and liver function enzymes changes during treatment period of Imatin...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/0019-509X.176715

    authors: Moshfeghi K,Nazemizadeh N,Mehrzad V,Hajiannejad A,Esmaeili F,Mohammadbeigi A

    更新日期:2015-07-01 00:00:00

  • Outcome analysis of benign vocal cord tumors treated by laryngeal endoscopy under low temperature-controlled radiofrequency.

    abstract:OBJECTIVE:This study aimed to evaluate the outcome of benign vocal cord tumors treated using a laryngeal endoscopy under low temperature-controlled radiofrequency and to elucidate the application of a dynamic laryngoendoscopy in the operation. MATERIALS AND METHODS:85 patients with benign vocal cord tumors were treate...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/0019-509X.151994

    authors: Wang ZY,Xu L,Wu KM,Zhang Y,Chen W

    更新日期:2015-02-01 00:00:00

  • Time, distance, shielding and ALARA; drawing similarities between measures for radiation protection and Coronavirus disease pandemic response.

    abstract::The practice of radiation oncology requires stringent adherence to specific steps and principles designed to minimize exposure of an individual to unnecessary doses of radiation. The basic principles of such measures to reduce the risk of exposure and limit the doses of irradiation follow the "as low as reasonably ach...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/ijc.IJC_343_20

    authors: Mukherji A,Gupta T,Agarwal JP

    更新日期:2020-04-01 00:00:00

  • Is histologic differentiation a prognostic indicator for gastric carcinoma patients with curative resection?

    abstract:BACKGROUND:The prognostic relevance of histologic differentiation in gastric carcinoma patients with curative resection is unclear. We analyzed the clinicopathologic features of gastric carcinoma patients with curative resection according to the histologic differentiation and evaluated surgical outcome. MATERIALS AND ...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/0019-509X.175569

    authors: Ryu SY,Kim HG,Joo JK,Kang H,Lee JH,Kim DY

    更新日期:2015-01-01 00:00:00

  • Surgical management of renal cell carcinoma with inferior vena caval thrombus: a teaching hospital experience.

    abstract:PURPOSE:To evaluate the outcome of patients of renal cell carcinoma (RCC) with inferior vena caval (IVC) thrombus treated by radical nephrectomy and IVC thrombectomy in terms of clinical and pathological factors and prognosis. MATERIALS AND METHODS:Sixty-three consecutive patients of RCC with IVC thrombus who underwen...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/0019-509x.35810

    authors: Kulkarni JN,Acharya PU,Rizvi SJ,Somaya AC

    更新日期:2007-04-01 00:00:00

  • A clinicopathological and immunohistochemical study of non-urothelial bladder tumours.

    abstract:BACKGROUND:Non-urothelial bladder tumors (NUBTs) are uncommon accounting for approximately 10% of the total urinary bladder tumors while 90% are urothelial in origin. There are very limited comprehensive studies on NUBTs. AIMS AND OBJECTIVES:The objectives of the study were to analyze the clinicopathological and immun...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/ijc.IJC_459_17

    authors: Kaur S,Gupta A,Gulwani HV

    更新日期:2019-07-01 00:00:00

  • Pleomorphic intimal sarcoma of pulmonary artery. A case report.

    abstract::A rare case of pleomorphic intimal sarcoma of pulmonary trunk is reported. The patient presented with symptoms of right ventricular out flow tract (RVOT) obstruction. Metastatic deposits were seen in lungs, diaphragm and thyroid. Bronchial mucosal involvement was also seen. The tumour showed multicentric origin and on...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:

    authors: Pandit SP,Chitale AR,Shah VK

    更新日期:1990-12-01 00:00:00

  • Chemosuppressive effect of plumbagin on human non-small lung cancer cell xenotransplanted zebrafish.

    abstract:BACKGROUND:Plumbagin (5-hydroxy-2-methyl-1,4-napthoquinone) derived from Plumbago species is a potential anti-tumour agent. Plumbagin has been tested for anti-cancer activity in vitro and in vivo using mice model. AIM:To study the tumour suppressing efficacy of plumbagin using zebrafish model. MATERIALS AND METHODS:H...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/0019-509X.219580

    authors: Vinothkumar R,Ceasar SA,Divyarupa A

    更新日期:2017-01-01 00:00:00

  • Carcinoma of the urinary bladder metastatic to the oral cavity.

    abstract::Oral Metastasis from a carcinoma of the urinary Bladder is extremely uncommon. Two cases of transitional cell carcinoma of the Bladder, presenting eighteen and ten months after initial diagnosis, one with soft tissue metastasis in the upper alveolus and the other with bony metastasis to the mandible are discussed. ...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:

    authors: Doval DC,Naresh KN,Sabitha KS,Vijaykumar M,Bapsy PP,Anantha N,Kumarswamy SV

    更新日期:1994-03-01 00:00:00

  • Importance of repeat tissue biopsy and tissue-based epidermal growth factor receptor T790M testing in progressed nonsmall cell lung carcinoma patients upon negative plasma genotyping for selection of third-generation tyrosine kinase inhibitor therapy: A c

    abstract::Resistance to 1st or 2nd generation epidermal growth factor receptor (EGFR) - tyrosine kinases (TKIs) develops predominantly due to an acquired mutation, EGFR T790M. Third-generation EGFR-TKIs have demonstrated potent activity against TKI resistance mediated by EGFR T790M. Thus, it become critical to identify T790M mu...

    journal_title:Indian journal of cancer

    pub_type:

    doi:10.4103/ijc.IJC_545_17

    authors: Mistry R,Patil A

    更新日期:2017-12-01 00:00:00

  • Chemistry and toxicology of smokeless tobacco.

    abstract::In most parts of the world, tobacco is used for smoking, whereas, in India, tobacco is used for smoking as well as in diverse smokeless forms. Absorption of toxic and carcinogenic chemicals in tobacco and other ingredients added to various products are causally associated with several non-communicable diseases includi...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章,评审

    doi:10.4103/0019-509X.107735

    authors: Bhisey RA

    更新日期:2012-10-01 00:00:00

  • Frequency of bacterial isolates and pattern of antimicrobial resistance in patients with hematological malignancies: A snapshot from tertiary cancer center.

    abstract:BACKGROUND:Infections are the most important cause of mortality in patients with high-risk febrile neutropenia. Emergence of multi-drug resistant organisms (MDROs) has become a major challenge for hemato-oncologists. Knowledge of the prevalent organisms and their antimicrobial sensitivity can help deciding the empirica...

    journal_title:Indian journal of cancer

    pub_type: 杂志文章

    doi:10.4103/0019-509X.175387

    authors: Sengar M,Kelkar R,Jain H,Biswas S,Pawaskar P,Karpe A

    更新日期:2014-10-01 00:00:00