Abstract:
BACKGROUND:Non-urothelial bladder tumors (NUBTs) are uncommon accounting for approximately 10% of the total urinary bladder tumors while 90% are urothelial in origin. There are very limited comprehensive studies on NUBTs. AIMS AND OBJECTIVES:The objectives of the study were to analyze the clinicopathological and immunohistochemical features of NUBTs. MATERIALS AND METHODS:This is a retrospective study of NUBTs diagnosed over a period of 9 years. Patients' files were retrieved from the archives. Gross and microscopic features were recorded. Simple percentage and frequencies were used to interpret the data. RESULTS:A total 16 cases (10.8% of all bladder tumors) of NUBT were found. Patients' ages ranged from 19 to 87 years with a male: female ratio of 4.3:1. The most common presenting symptom was gross hematuria (81.2%), and the most common location was posterolateral bladder wall. Muscle invasion was seen in 81.2% of cases, and large areas of necrosis were observed in 62.5%. There were two cases of squamous cell carcinoma, five cases each of adenocarcinoma (four secondary and one urachal) and mesenchymal tumors (four malignant and one benign), two cases of amyloid, and one case each of plasmacytomas and paraganglioma. Large areas of necrosis and muscle invasion were noted in high-grade and advanced staged tumors. In all, 43.7% had poor survival. CONCLUSION:NUBTs present with similar clinicoradiological findings; however, their histological features along with immunohistochemistry help in the definite diagnosis. One should be aware of these tumors as they frequently present diagnostic and therapeutic challenge. Most of these neoplasms present at an advanced stage. Large or multicentric randomized controlled studies are needed to know the exact behavior and prognosis of these tumors.
journal_name
Indian J Cancerjournal_title
Indian journal of cancerauthors
Kaur S,Gupta A,Gulwani HVdoi
10.4103/ijc.IJC_459_17subject
Has Abstractpub_date
2019-07-01 00:00:00pages
254-260issue
3eissn
0019-509Xissn
1998-4774pii
IndianJournalofCancer_2019_56_3_254_263035journal_volume
56pub_type
杂志文章abstract::Five cases of primary lymphoma of the brain are reported and the literature reviewed. The diverse clinical spectrum at presentation and variable response to therapy are few of its unique features. The literature is reviewed briefly and the importance of diagnosis at an early stage and prompt institution of therapy in ...
journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:
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journal_title:Indian journal of cancer
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journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1997-09-01 00:00:00
abstract::Since 1987, 560 patients have been treated in our department for carcinoma of thyroid with radioactive Iodine-131. Recently, we have come across a patient with bilateral pulmonary concentration of Iodine-131, that is visualised on Iodine-131 whole body scintiscan, whereas chest radiogram was negative. Respectively, th...
journal_title:Indian journal of cancer
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journal_title:Indian journal of cancer
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journal_title:Indian journal of cancer
pub_type: 杂志文章,评审
doi:
更新日期:1999-06-01 00:00:00
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journal_title:Indian journal of cancer
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journal_title:Indian journal of cancer
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journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
更新日期:1993-03-01 00:00:00
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journal_title:Indian journal of cancer
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journal_title:Indian journal of cancer
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doi:
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journal_title:Indian journal of cancer
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journal_title:Indian journal of cancer
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journal_title:Indian journal of cancer
pub_type: 杂志文章
doi:
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