Exploring the trade-offs between electric heating policy and carbon mitigation in China.

abstract：:Lifespan is a trait of enormous personal interest. Research into the biological basis of human lifespan, however, is hampered by the long time to death. Using a novel approach of regressing (272,081) parental lifespans beyond age 40 years on participant genotype in a new large data set (UK Biobank), we here show that ...

journal_title：Nature communications

authors： Joshi PK,Fischer K,Schraut KE,Campbell H,Esko T,Wilson JF

更新日期：2016-03-31 00:00:00

abstract：:Phosphorylation is a major post-translational mechanism of regulation that frequently targets disordered protein domains, but it remains unclear how phosphorylation modulates disordered states of proteins. Here we determine the kinetics and energetics of a disordered protein domain the kinase-inducible domain (KID) of...

journal_title：Nature communications

authors： Stanley N,Esteban-Martín S,De Fabritiis G

更新日期：2014-10-28 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Zheng J,Fan R,Wu H,Yao H,Yan Y,Liu J,Ran L,Sun Z,Yi L,Dang L,Gan P,Zheng P,Yang T,Zhang Y,Tang T,Wang Y

更新日期：2020-07-27 00:00:00

abstract：:Self-assembly of small molecules in water to form nanofibres, besides generating sophisticated biomaterials, promises a simple system inside cells for regulating cellular processes. But lack of a convenient approach for studying the self-assembly of small molecules inside cells hinders the development of such systems....

journal_title：Nature communications

authors： Gao Y,Shi J,Yuan D,Xu B

更新日期：2012-01-01 00:00:00

abstract：:Zoonotic transmission of lethal henipaviruses (HNVs) from their natural fruit bat reservoirs to humans has only been reported in Australia and South/Southeast Asia. However, a recent study discovered numerous HNV clades in African bat samples. To determine the potential for HNV spillover events among humans in Africa,...

journal_title：Nature communications

authors： Pernet O,Schneider BS,Beaty SM,LeBreton M,Yun TE,Park A,Zachariah TT,Bowden TA,Hitchens P,Ramirez CM,Daszak P,Mazet J,Freiberg AN,Wolfe ND,Lee B

更新日期：2014-11-18 00:00:00

abstract：:Socioeconomic challenges continue to mount for half a billion residents of central India because of a decline in the total rainfall and a concurrent rise in the magnitude and frequency of extreme rainfall events. Alongside a weakening monsoon circulation, the locally available moisture and the frequency of moisture-la...

journal_title：Nature communications

authors： Roxy MK,Ghosh S,Pathak A,Athulya R,Mujumdar M,Murtugudde R,Terray P,Rajeevan M

更新日期：2017-10-03 00:00:00

abstract：:Apicomplexans are obligate intracellular parasites that scavenge essential nutrients from their hosts via transporter proteins on their plasma membrane. The identities of the transporters that mediate amino acid uptake into apicomplexans are unknown. Here we demonstrate that members of an apicomplexan-specific protein...

journal_title：Nature communications

authors： Rajendran E,Hapuarachchi SV,Miller CM,Fairweather SJ,Cai Y,Smith NC,Cockburn IA,Bröer S,Kirk K,van Dooren GG

更新日期：2017-02-16 00:00:00

abstract：:The negative-capacitance field-effect transistor(NC-FET) has attracted tremendous research efforts. However, the lack of a clear physical picture and design rule for this device has led to numerous invalid fabrications. In this work, we address this issue based on an unexpectedly concise and insightful analytical form...

journal_title：Nature communications

authors： Cao W,Banerjee K

更新日期：2020-01-10 00:00:00

abstract：:Activation of the Hippo pathway effector Yap underlies many liver cancers, however no germline or somatic mutations have been identified. Autophagy maintains essential metabolic functions of the liver, and autophagy-deficient murine models develop benign adenomas and hepatomegaly, which have been attributed to activat...

journal_title：Nature communications

authors： Lee YA,Noon LA,Akat KM,Ybanez MD,Lee TF,Berres ML,Fujiwara N,Goossens N,Chou HI,Parvin-Nejad FP,Khambu B,Kramer EGM,Gordon R,Pfleger C,Germain D,John GR,Campbell KN,Yue Z,Yin XM,Cuervo AM,Czaja MJ,Fiel MI,Hosh

更新日期：2018-11-23 00:00:00

abstract：:Electronic structure heterogeneities are ubiquitous in two-dimensional graphene and profoundly impact the transport properties of this material. Here we show the mapping of discrete electronic domains within a single graphene sheet using scanning transmission X-ray microscopy in conjunction with ab initio density func...

journal_title：Nature communications

authors： Schultz BJ,Patridge CJ,Lee V,Jaye C,Lysaght PS,Smith C,Barnett J,Fischer DA,Prendergast D,Banerjee S

更新日期：2011-06-28 00:00:00

abstract：:Domesticator-domesticate relationships are specialized mutualisms where one species provides multigenerational support to another in exchange for a resource or service, and through which both partners gain an advantage over individuals outside the relationship. While this ecological innovation has profoundly reshaped ...

journal_title：Nature communications

authors： Brooker RM,Casey JM,Cowan ZL,Sih TL,Dixson DL,Manica A,Feeney WE

更新日期：2020-12-07 00:00:00

abstract：:Among various flat optical devices, metasurfaces have presented their great ability in efficient manipulation of light fields and have been proposed for variety of devices with specific functionalities. However, due to the high phase dispersion of their building blocks, metasurfaces significantly suffer from large chr...

journal_title：Nature communications

authors： Wang S,Wu PC,Su VC,Lai YC,Hung Chu C,Chen JW,Lu SH,Chen J,Xu B,Kuan CH,Li T,Zhu S,Tsai DP

更新日期：2017-08-04 00:00:00

abstract：:Calcareous microplankton shells form the dominant components of ancient and modern pelagic sea-floor carbonates and are widely used in palaeoenvironmental reconstructions. The efficacy of these applications, however, is dependent upon minimal geochemical alteration during diagenesis, but these modifying processes are ...

journal_title：Nature communications

authors： Wendler JE,Bown P

更新日期：2013-01-01 00:00:00

abstract：:The interconversion of charge and spin currents via spin-Hall effect is essential for spintronics. Energy-efficient and deterministic switching of magnetization can be achieved when spin polarizations of these spin currents are collinear with the magnetization. However, symmetry conditions generally restrict spin pola...

journal_title：Nature communications

authors： Nan T,Quintela CX,Irwin J,Gurung G,Shao DF,Gibbons J,Campbell N,Song K,Choi S-,Guo L,Johnson RD,Manuel P,Chopdekar RV,Hallsteinsen I,Tybell T,Ryan PJ,Kim J-,Choi Y,Radaelli PG,Ralph DC,Tsymbal EY,Rzchowski MS,

更新日期：2020-09-16 00:00:00

abstract：:In-plane anisotropic ground states are ubiquitous in correlated solids such as pnictides, cuprates and manganites. They can arise from doping Mott insulators and compete with phases such as superconductivity; however, their origins are debated. Strong coupling between lattice, charge, orbital and spin degrees of freed...

journal_title：Nature communications

authors： Miller TA,Chhajlany RW,Tagliacozzo L,Green B,Kovalev S,Prabhakaran D,Lewenstein M,Gensch M,Wall S

更新日期：2015-09-18 00:00:00

abstract：:Azobenzene, a versatile and polymorphic molecule, has been extensively and successfully used for photoswitching applications. The debate over its photoisomerization mechanism leveraged on the computational scrutiny with ever-increasing levels of theory. However, the most resolved absorption spectrum for the transition...

journal_title：Nature communications

authors： Tan EM,Amirjalayer S,Smolarek S,Vdovin A,Zerbetto F,Buma WJ

更新日期：2015-01-06 00:00:00

abstract：:ARID1A, a component of the SWI/SNF chromatin remodeling complex, is a tumor suppressor with a high frequency of inactivating mutations in many cancers. Therefore, ARID1A deficiency has been exploited therapeutically for treating cancer. Here we show that ARID1A has a synthetic lethal interaction with aurora kinase A (...

journal_title：Nature communications

authors： Wu C,Lyu J,Yang EJ,Liu Y,Zhang B,Shim JS

更新日期：2018-08-10 00:00:00

abstract：:Free-electron lasers providing ultra-short high-brightness pulses of X-ray radiation have great potential for a wide impact on science, and are a critical element for unravelling the structural dynamics of matter. To fully harness this potential, we must accurately know the X-ray properties: intensity, spectrum and te...

journal_title：Nature communications

authors： Sanchez-Gonzalez A,Micaelli P,Olivier C,Barillot TR,Ilchen M,Lutman AA,Marinelli A,Maxwell T,Achner A,Agåker M,Berrah N,Bostedt C,Bozek JD,Buck J,Bucksbaum PH,Montero SC,Cooper B,Cryan JP,Dong M,Feifel R,Frasinski

更新日期：2017-06-05 00:00:00

abstract：:It has been suggested that deficient protein trafficking to the cell membrane is the dominant mechanism associated with type 2 Long QT syndrome (LQT2) caused by Kv11.1 potassium channel missense mutations, and that for many mutations the trafficking defect can be corrected pharmacologically. However, this inference wa...

journal_title：Nature communications

authors： Anderson CL,Kuzmicki CE,Childs RR,Hintz CJ,Delisle BP,January CT

更新日期：2014-11-24 00:00:00

abstract：:Sensory perception modulates health and aging across taxa. Understanding the nature of relevant cues and the mechanisms underlying their action may lead to novel interventions that improve the length and quality of life. We found that in the vinegar fly, Drosophila melanogaster, exposure to dead conspecifics in the en...

journal_title：Nature communications

authors： Chakraborty TS,Gendron CM,Lyu Y,Munneke AS,DeMarco MN,Hoisington ZW,Pletcher SD

更新日期：2019-05-30 00:00:00

abstract：:The original version of this Article contained an error in Fig. 3. The scale bars in Figs 3c and 3d were incorrectly labelled as 50 μA. In the correct version, the scale bars are labelled as 0.5 μA. This has now been corrected in both the PDF and HTML versions of the Article. ...

journal_title：Nature communications

authors： Li X,Zhai T,Gao P,Cheng H,Hou R,Lou X,Xia F

更新日期：2018-02-08 00:00:00

abstract：:Intracranial aneurysm is a common life-threatening disease. Computed tomography angiography is recommended as the standard diagnosis tool; yet, interpretation can be time-consuming and challenging. We present a specific deep-learning-based model trained on 1,177 digital subtraction angiography verified bone-removal co...

journal_title：Nature communications

authors： Shi Z,Miao C,Schoepf UJ,Savage RH,Dargis DM,Pan C,Chai X,Li XL,Xia S,Zhang X,Gu Y,Zhang Y,Hu B,Xu W,Zhou C,Luo S,Wang H,Mao L,Liang K,Wen L,Zhou L,Yu Y,Lu GM,Zhang LJ

更新日期：2020-11-30 00:00:00

abstract：:Amontons' law defines the friction coefficient as the ratio between friction force and normal force, and assumes that both these forces depend linearly on the real contact area between the two sliding surfaces. However, experimental testing of frictional contact models has proven difficult, because few in situ experim...

journal_title：Nature communications

authors： Weber B,Suhina T,Junge T,Pastewka L,Brouwer AM,Bonn D

更新日期：2018-03-01 00:00:00

abstract：:Heart failure (HF) is a leading cause of mortality. Inflammation is implicated in HF, yet clinical trials targeting pro-inflammatory cytokines in HF were unsuccessful, possibly due to redundant functions of individual cytokines. Searching for better cardiac inflammation targets, here we link T cells with HF developmen...

journal_title：Nature communications

authors： Kallikourdis M,Martini E,Carullo P,Sardi C,Roselli G,Greco CM,Vignali D,Riva F,Ormbostad Berre AM,Stølen TO,Fumero A,Faggian G,Di Pasquale E,Elia L,Rumio C,Catalucci D,Papait R,Condorelli G

更新日期：2017-03-06 00:00:00

abstract：:Quantum computers promise to solve certain problems more efficiently than their digital counterparts. A major challenge towards practically useful quantum computing is characterizing and reducing the various errors that accumulate during an algorithm running on large-scale processors. Current characterization techniqu...

journal_title：Nature communications

authors： Erhard A,Wallman JJ,Postler L,Meth M,Stricker R,Martinez EA,Schindler P,Monz T,Emerson J,Blatt R

更新日期：2019-11-25 00:00:00

abstract：:Proactive, that is, unsolicited, prosociality is a key component of our hyper-cooperation, which in turn has enabled the emergence of various uniquely human traits, including complex cognition, morality and cumulative culture and technology. However, the evolutionary foundation of the human prosocial sentiment remains...

journal_title：Nature communications

authors： Burkart JM,Allon O,Amici F,Fichtel C,Finkenwirth C,Heschl A,Huber J,Isler K,Kosonen ZK,Martins E,Meulman EJ,Richiger R,Rueth K,Spillmann B,Wiesendanger S,van Schaik CP

更新日期：2014-08-27 00:00:00

abstract：:The engineering of nanoscale features enables the properties of solid-state materials to be tuned. Here, we show the tunable preparation of cuprous sulfide nanocrystals ranging in internal structures from single-domain to multi-domain. The synthetic method utilizes in-situ oxidation to grow nanocrystals with a control...

journal_title：Nature communications

authors： Gong J,Jain PK

更新日期：2019-07-23 00:00:00

abstract：:It is commonly assumed that neural systems efficiently process natural sensory input. However, the mechanisms by which such efficient processing is achieved, and the consequences for perception and behaviour remain poorly understood. Here we show that small conductance calcium-activated potassium (SK) channels enable ...

journal_title：Nature communications

authors： Huang CG,Zhang ZD,Chacron MJ

更新日期：2016-04-18 00:00:00

abstract：:Under hypoxia, most of glucose is converted to secretory lactate, which leads to the overuse of glutamine-carbon. However, under such a condition how glutamine nitrogen is disposed to avoid over-accumulating ammonia remains to be determined. Here we identify a metabolic flux of glutamine to secretory dihydroorotate, w...

journal_title：Nature communications

authors： Wang Y,Bai C,Ruan Y,Liu M,Chu Q,Qiu L,Yang C,Li B

更新日期：2019-01-14 00:00:00

abstract：:Broomcorn millet (Panicum miliaceum L.) has strong tolerance to abiotic stresses, and is probably one of the oldest crops, with its earliest cultivation that dated back to ca. ~10,000 years. We report here its genome assembly through a combination of PacBio sequencing, BioNano, and Hi-C (in vivo) mapping. The 18 super...

journal_title：Nature communications

authors： Shi J,Ma X,Zhang J,Zhou Y,Liu M,Huang L,Sun S,Zhang X,Gao X,Zhan W,Li P,Wang L,Lu P,Zhao H,Song W,Lai J

更新日期：2019-01-25 00:00:00