Evidence for henipavirus spillover into human populations in Africa.

abstract：:Elemental phosphorus is attracting growing interest across fundamental and applied fields of research. However, atomistic simulations of phosphorus have remained an outstanding challenge. Here, we show that a universally applicable force field for phosphorus can be created by machine learning (ML) from a suitably chos...

journal_title：Nature communications

authors： Deringer VL,Caro MA,Csányi G

更新日期：2020-10-29 00:00:00

abstract：:Molecular spins have become key enablers for exploring magnetic interactions, quantum information processes and many-body effects in metals. Metal-organic molecules, in particular, let the spin state of the core metal ion to be modified according to its organic environment, allowing localized magnetic moments to emerg...

journal_title：Nature communications

authors： Atxabal A,Ribeiro M,Parui S,Urreta L,Sagasta E,Sun X,Llopis R,Casanova F,Hueso LE

更新日期：2016-12-12 00:00:00

abstract：:Multipotent mesenchymal stromal cells (MSCs) are required for skeletal formation, maintenance, and repair throughout life; however, current models posit that postnatally arising long-lived adult MSCs replace transient embryonic progenitor populations. We previously reported exclusive expression and function of the emb...

journal_title：Nature communications

authors： Pineault KM,Song JY,Kozloff KM,Lucas D,Wellik DM

更新日期：2019-07-18 00:00:00

abstract：:Metastasis is the main cause of cancer-related death and thus understanding the molecular and cellular mechanisms underlying this process is critical. Here, our data demonstrate, contrary to established dogma, that loss of haematopoietic-derived focal adhesion kinase (FAK) is sufficient to enhance tumour metastasis. U...

journal_title：Nature communications

authors： Batista S,Maniati E,Reynolds LE,Tavora B,Lees DM,Fernandez I,Elia G,Casanovas O,Lo Celso C,Hagemann T,Hodivala-Dilke K

更新日期：2014-10-01 00:00:00

abstract：:Oceanic mesoscale eddies contribute important horizontal heat and salt transports on a global scale. Here we show that eddy transports are mainly due to individual eddy movements. Theoretical and observational analyses indicate that cyclonic and anticyclonic eddies move westwards, and they also move polewards and equa...

journal_title：Nature communications

authors： Dong C,McWilliams JC,Liu Y,Chen D

更新日期：2014-01-01 00:00:00

abstract：:Hydrothermal synthesis is challenging in metal oxide systems with diverse polymorphism, as reaction products are often sensitive to subtle variations in synthesis parameters. This sensitivity is rooted in the non-equilibrium nature of low-temperature crystallization, where competition between different metastable phas...

journal_title：Nature communications

authors： Chen BR,Sun W,Kitchaev DA,Mangum JS,Thampy V,Garten LM,Ginley DS,Gorman BP,Stone KH,Ceder G,Toney MF,Schelhas LT

更新日期：2018-06-29 00:00:00

abstract：:Supported gold (Au) nanocatalysts have attracted extensive interests in the past decades because of their unique catalytic properties for a number of key chemical reactions, especially in (selective) oxidations. The activation of O2 on Au nanocatalysts is crucial and remains a challenge because only small Au nanoparti...

journal_title：Nature communications

authors： Zhang Y,Zhang J,Zhang B,Si R,Han B,Hong F,Niu Y,Sun L,Li L,Qiao B,Sun K,Huang J,Haruta M

更新日期：2020-01-28 00:00:00

abstract：:Therapeutic strategies for spinal cord injury (SCI) commonly focus on regenerating disconnected axons. An alternative approach would be to maintain continuity of damaged axons, especially after contusion. The viability of such neuropreservative strategies depends on the degree to which initially injured axons can reco...

journal_title：Nature communications

authors： Williams PR,Marincu BN,Sorbara CD,Mahler CF,Schumacher AM,Griesbeck O,Kerschensteiner M,Misgeld T

更新日期：2014-12-16 00:00:00

abstract：:Ribosomes are essential intracellular machines composed of proteins and RNA molecules. The DNA sequences (rDNA) encoding ribosomal RNAs (rRNAs) are tandemly repeated and give origin to the nucleolus. Here we develop a computational method for estimating rDNA dosage (copy number) and mitochondrial DNA abundance using w...

journal_title：Nature communications

authors： Gibbons JG,Branco AT,Yu S,Lemos B

更新日期：2014-09-11 00:00:00

abstract：:Aerosol-cloud interactions constitute the largest source of uncertainty in global radiative forcing estimates, hampering our understanding of climate evolution. Recent empirical evidence suggests surface tension depression by organic aerosol to significantly influence the formation of cloud droplets, and hence cloud o...

journal_title：Nature communications

authors： Lowe SJ,Partridge DG,Davies JF,Wilson KR,Topping D,Riipinen I

更新日期：2019-11-18 00:00:00

abstract：:Complex tissue-specific and cell-specific signaling by the estrogen receptor (ER) frequently leads to the development of resistance to endocrine therapy for breast cancer. Pure ER antagonists, which completely lack tissue-specific agonist activity, hold promise for preventing and treating endocrine resistance, however...

journal_title：Nature communications

authors： Fanning SW,Hodges-Gallagher L,Myles DC,Sun R,Fowler CE,Plant IN,Green BD,Harmon CL,Greene GL,Kushner PJ

更新日期：2018-06-18 00:00:00

abstract：:Circular RNAs (circRNAs) have recently gained substantial attention in the cancer research field where most, including the putative oncogene ciRS-7 (CDR1as), have been proposed to function as competitive endogenous RNAs (ceRNAs) by sponging specific microRNAs. Here, we report the first spatially resolved cellular expr...

journal_title：Nature communications

authors： Kristensen LS,Ebbesen KK,Sokol M,Jakobsen T,Korsgaard U,Eriksen AC,Hansen TB,Kjems J,Hager H

更新日期：2020-09-11 00:00:00

abstract：:With damage tolerance rivalling advanced engineering alloys and thermoplastic forming capabilities analogous to conventional plastics, metallic glasses are emerging as a modern engineering material. Here, we take advantage of their unique electrical and rheological properties along with the classic Lorentz force conce...

journal_title：Nature communications

authors： Kaltenboeck G,Demetriou MD,Roberts S,Johnson WL

更新日期：2016-02-08 00:00:00

abstract：:Interfacial water constitutes a formidable barrier to strong surface bonding, hampering the development of water-resistant synthetic adhesives. Notwithstanding this obstacle, the Asian green mussel Perna viridis attaches firmly to underwater surfaces via a proteinaceous secretion (byssus). Extending beyond the current...

journal_title：Nature communications

authors： Petrone L,Kumar A,Sutanto CN,Patil NJ,Kannan S,Palaniappan A,Amini S,Zappone B,Verma C,Miserez A

更新日期：2015-10-28 00:00:00

abstract：:Phagocytosis is responsible for the elimination of particles of widely disparate sizes, from large fungi or effete cells to small bacteria. Though superficially similar, the molecular mechanisms involved differ: engulfment of large targets requires phosphoinositide 3-kinase (PI3K), while that of small ones does not. H...

journal_title：Nature communications

authors： Schlam D,Bagshaw RD,Freeman SA,Collins RF,Pawson T,Fairn GD,Grinstein S

更新日期：2015-10-14 00:00:00

abstract：:Transcranial electrical stimulation has widespread clinical and research applications, yet its effect on ongoing neural activity in humans is not well established. Previous reports argue that transcranial alternating current stimulation (tACS) can entrain and enhance neural rhythms related to memory, but the evidence ...

journal_title：Nature communications

authors： Lafon B,Henin S,Huang Y,Friedman D,Melloni L,Thesen T,Doyle W,Buzsáki G,Devinsky O,Parra LC,A Liu A

更新日期：2017-10-31 00:00:00

abstract：:Plasmacytoid dendritic cells (pDC) are type I interferon-producing cells with critical functions in a number of human illnesses; however, their molecular regulation is incompletely understood. Here we show the role of Src family kinases (SFK) in mouse and human pDCs. pDCs express Fyn and Lyn and their activating resid...

journal_title：Nature communications

authors： Dallari S,Macal M,Loureiro ME,Jo Y,Swanson L,Hesser C,Ghosh P,Zuniga EI

更新日期：2017-04-03 00:00:00

abstract：:Acute graft-versus-host disease (GVHD) remains a major obstacle for the wider usage of allogeneic hematopoietic stem cell transplantation (allo-HSCT), which is an effective therapy for hematopoietic malignancy. Here we show that caspase-11, the cytosolic receptor for bacterial endotoxin (lipopolysaccharide: LPS), enha...

journal_title：Nature communications

authors： Lu Y,Meng R,Wang X,Xu Y,Tang Y,Wu J,Xue Q,Yu S,Duan M,Shan D,Wang Q,Wang H,Billiar TR,Xiao X,Chen F,Lu B

更新日期：2019-09-06 00:00:00

abstract：:Despite the increasing resolution, forcing on the mean circulation by resolved waves in general circulation models is not yet converging. Parameterization of the forcing remains a major source of model uncertainty. This study examines the scale invariance of zonal spectra of momentum flux and wave forcing, and shows t...

journal_title：Nature communications

authors： Liu HL

更新日期：2019-06-13 00:00:00

abstract：:Two-Photon Microscopy has become an invaluable tool for biological and medical research, providing high sensitivity, molecular specificity, inherent three-dimensional sub-cellular resolution and deep tissue penetration. In terms of imaging speeds, however, mechanical scanners still limit the acquisition rates to typic...

journal_title：Nature communications

authors： Karpf S,Riche CT,Di Carlo D,Goel A,Zeiger WA,Suresh A,Portera-Cailliau C,Jalali B

更新日期：2020-04-28 00:00:00

abstract：:In the central nervous system, most synapses show a fast mode of neurotransmitter release known as synchronous release followed by a phase of asynchronous release, which extends over tens of milliseconds to seconds. Synapsin II (SYN2) is a member of the multigene synapsin family (SYN1/2/3) of synaptic vesicle phosphop...

journal_title：Nature communications

authors： Medrihan L,Cesca F,Raimondi A,Lignani G,Baldelli P,Benfenati F

更新日期：2013-01-01 00:00:00

abstract：:A new paradigm for cellulose depolymerization by fungi focuses on an oxidative mechanism involving cellobiose dehydrogenases (CDH) and copper-dependent lytic polysaccharide monooxygenases (LPMO); however, mechanistic studies have been hampered by the lack of structural information regarding CDH. CDH contains a haem-bi...

journal_title：Nature communications

authors： Tan TC,Kracher D,Gandini R,Sygmund C,Kittl R,Haltrich D,Hällberg BM,Ludwig R,Divne C

更新日期：2015-07-07 00:00:00

abstract：:Microbial communities mediating anaerobic ammonium oxidation (anammox) represent one of the most energy-efficient environmental biotechnologies for nitrogen removal from wastewater. However, little is known about the functional role heterotrophic bacteria play in anammox granules. Here, we use genome-centric metagenom...

journal_title：Nature communications

authors： Lawson CE,Wu S,Bhattacharjee AS,Hamilton JJ,McMahon KD,Goel R,Noguera DR

更新日期：2017-05-31 00:00:00

abstract：:Planar spindle orientation in polarized epithelial cells depends on the precise localization of the dynein-dynactin motor protein complex at the lateral cortex. The contribution of cell adhesion molecules to the cortical localization of the dynein-dynactin complex is poorly understood. Here we find that junctional adh...

journal_title：Nature communications

authors： Tuncay H,Brinkmann BF,Steinbacher T,Schürmann A,Gerke V,Iden S,Ebnet K

更新日期：2015-08-26 00:00:00

abstract：:Knots are natural topologies of chains. Yet, little is known about spontaneous knot formation in a polypeptide chain-an event that can potentially impair its folding-and about the effect of a knot on the stability and folding kinetics of a protein. Here we used optical tweezers to show that the free energy cost to for...

journal_title：Nature communications

authors： Bustamante A,Sotelo-Campos J,Guerra DG,Floor M,Wilson CAM,Bustamante C,Báez M

更新日期：2017-11-17 00:00:00

abstract：:Microelectromechanical systems (MEMS) enable many modern-day technologies, including actuators, motion sensors, drug delivery systems, projection displays, etc. Currently, MEMS fabrication techniques are primarily based on silicon micromachining processes, resulting in rigid and low aspect ratio structures. In this st...

journal_title：Nature communications

authors： Khudiyev T,Clayton J,Levy E,Chocat N,Gumennik A,Stolyarov AM,Joannopoulos J,Fink Y

更新日期：2017-11-10 00:00:00

abstract：:Electroreduction of carbon dioxide into higher-energy liquid fuels and chemicals is a promising but challenging renewable energy conversion technology. Among the electrocatalysts screened so far for carbon dioxide reduction, which includes metals, alloys, organometallics, layered materials and carbon nanostructures, o...

journal_title：Nature communications

authors： Wu J,Ma S,Sun J,Gold JI,Tiwary C,Kim B,Zhu L,Chopra N,Odeh IN,Vajtai R,Yu AZ,Luo R,Lou J,Ding G,Kenis PJ,Ajayan PM

更新日期：2016-12-13 00:00:00

abstract：:An elusive goal in the field of driven quantum matter is the induction of long-range order. Here, we propose a mechanism based on light-induced evaporative cooling of holes in a correlated fermionic system. Since the entropy of a filled narrow band grows rapidly with hole doping, the isentropic transfer of holes from ...

journal_title：Nature communications

authors： Werner P,Eckstein M,Müller M,Refael G

更新日期：2019-12-05 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Maury MM,Bracq-Dieye H,Huang L,Vales G,Lavina M,Thouvenot P,Disson O,Leclercq A,Brisse S,Lecuit M

更新日期：2019-08-06 00:00:00

abstract：:The degraded, misfolded C terminus of TAR DNA-binding protein-43 is associated with a wide spectrum of neurodegenerative diseases, particularly frontotemporal lobar degeneration with ubiquitin-positive inclusions and amyotrophic lateral sclerosis. However, the precise mechanism of pathological cleavage of the TAR DNA-...

journal_title：Nature communications

authors： Wang IF,Chang HY,Hou SC,Liou GG,Way TD,James Shen CK

更新日期：2012-04-03 00:00:00