A threefold rise in widespread extreme rain events over central India.

abstract：:We constructed an intelligent cloud lab that integrates lab automation with cloud servers and artificial intelligence (AI) to detect chirality in perovskites. Driven by the materials acceleration operating system in cloud (MAOSIC) platform, on-demand experimental design by remote users was enabled in this cloud lab. B...

journal_title：Nature communications

authors： Li J,Li J,Liu R,Tu Y,Li Y,Cheng J,He T,Zhu X

更新日期：2020-04-27 00:00:00

abstract：:Chemical modifications on DNA molecules, such as 5-methylcytosine and 5-hydroxymethylcytosine, play important roles in the mammalian brain. A novel DNA adenine modification, N(6)-methyladenine (6mA), has recently been found in mammalian cells. However, the presence and function(s) of 6mA in the mammalian brain remain ...

journal_title：Nature communications

authors： Yao B,Cheng Y,Wang Z,Li Y,Chen L,Huang L,Zhang W,Chen D,Wu H,Tang B,Jin P

更新日期：2017-10-24 00:00:00

abstract：:Despite the global impact of macrophage activation in vascular disease, the underlying mechanisms remain obscure. Here we show, with global proteomic analysis of macrophage cell lines treated with either IFNγ or IL-4, that PARP9 and PARP14 regulate macrophage activation. In primary macrophages, PARP9 and PARP14 have o...

journal_title：Nature communications

authors： Iwata H,Goettsch C,Sharma A,Ricchiuto P,Goh WW,Halu A,Yamada I,Yoshida H,Hara T,Wei M,Inoue N,Fukuda D,Mojcher A,Mattson PC,Barabási AL,Boothby M,Aikawa E,Singh SA,Aikawa M

更新日期：2016-10-31 00:00:00

abstract：:Intense ultrashort X-ray pulses produced by modern free-electron lasers (FELs) allow one to probe biological systems, inorganic materials and molecular reaction dynamics with nanoscale spatial and femtoscale temporal resolution. These experiments require the knowledge, and possibly the control, of the spectro-temporal...

journal_title：Nature communications

authors： De Ninno G,Gauthier D,Mahieu B,Ribič PR,Allaria E,Cinquegrana P,Danailov MB,Demidovich A,Ferrari E,Giannessi L,Penco G,Sigalotti P,Stupar M

更新日期：2015-08-20 00:00:00

abstract：:Naturally-occurring thermal materials usually possess specific thermal conductivity (κ), forming a digital set of κ values. Emerging thermal metamaterials have been deployed to realize effective thermal conductivities unattainable in natural materials. However, the effective thermal conductivities of such mixing-based...

journal_title：Nature communications

authors： Xu G,Dong K,Li Y,Li H,Liu K,Li L,Wu J,Qiu CW

更新日期：2020-11-27 00:00:00

abstract：:The coupling of compartmentalisation with molecular replication is thought to be crucial for the emergence of the first evolvable chemical systems. Minimal artificial replicators have been designed based on molecular recognition, inspired by the template copying of DNA, but none yet have been coupled to compartmentali...

journal_title：Nature communications

authors： Taylor JW,Eghtesadi SA,Points LJ,Liu T,Cronin L

更新日期：2017-08-10 00:00:00

abstract：:Glucocorticoids are among the most commonly used anti-inflammatory agents. Despite the enormous efforts in elucidating the glucocorticoid-mediated anti-inflammatory actions, how glucocorticoids tightly control overactive inflammatory response is not fully understood. Here we show that glucocorticoids suppress bacteria...

journal_title：Nature communications

authors： Miyata M,Lee JY,Susuki-Miyata S,Wang WY,Xu H,Kai H,Kobayashi KS,Flavell RA,Li JD

更新日期：2015-01-14 00:00:00

abstract：:Stacking faults are known as defective structures in crystalline materials that typically lower the structural quality of the material. Here, we show that a particular type of defect, that is, stacking fault tetrahedra (SFTs), exhibits pronounced quantized electronic behaviour, revealing a potential synthetic route to...

journal_title：Nature communications

authors： Schouteden K,Amin-Ahmadi B,Li Z,Muzychenko D,Schryvers D,Van Haesendonck C

更新日期：2016-12-23 00:00:00

abstract：:Storage of chromatin in restricted nuclear space requires dense packing while ensuring DNA accessibility. Thus, different layers of chromatin organization and epigenetic control mechanisms exist. Genome-wide chromatin interaction maps revealed large interaction domains (TADs) and higher order A and B compartments, ref...

journal_title：Nature communications

authors： Nothjunge S,Nührenberg TG,Grüning BA,Doppler SA,Preissl S,Schwaderer M,Rommel C,Krane M,Hein L,Gilsbach R

更新日期：2017-11-21 00:00:00

abstract：:Genomic changes observed across treatment may result from either clonal evolution or geographically disparate sampling of heterogeneous tumors. Here we use computational modeling based on analysis of fifteen primary breast tumors and find that apparent clonal change between two tumor samples can frequently be explaine...

journal_title：Nature communications

authors： Caswell-Jin JL,McNamara K,Reiter JG,Sun R,Hu Z,Ma Z,Ding J,Suarez CJ,Tilk S,Raghavendra A,Forte V,Chin SF,Bardwell H,Provenzano E,Caldas C,Lang J,West R,Tripathy D,Press MF,Curtis C

更新日期：2019-02-08 00:00:00

abstract：:Ferroelectric domain walls constitute a completely new class of sheet-like functional material. Moreover, since domain walls are generally writable, erasable and mobile, they could be useful in functionally agile devices: for example, creating and moving conducting walls could make or break electrical connections in n...

journal_title：Nature communications

authors： McQuaid RGP,Campbell MP,Whatmore RW,Kumar A,Gregg JM

更新日期：2017-05-16 00:00:00

abstract：:Polycomb repressive complex 2 (PRC2) controls maintenance and lineage determination of stem cells by suppressing genes that regulate cellular differentiation and tissue development. However, the role of PRC2 in lineage-committed somatic cells is mostly unknown. Here we show that Eed deficiency in chondrocytes causes s...

journal_title：Nature communications

authors： Mirzamohammadi F,Papaioannou G,Inloes JB,Rankin EB,Xie H,Schipani E,Orkin SH,Kobayashi T

更新日期：2016-06-22 00:00:00

abstract：:It is unclear whether the establishment of apical-basal cell polarity during the generation of epithelial lumens requires molecules acting at the plasma membrane/actin interface. Here, we show that the I-BAR-containing IRSp53 protein controls lumen formation and the positioning of the polarity determinants aPKC and po...

journal_title：Nature communications

authors： Bisi S,Marchesi S,Rizvi A,Carra D,Beznoussenko GV,Ferrara I,Deflorian G,Mironov A,Bertalot G,Pisati F,Oldani A,Cattaneo A,Saberamoli G,Pece S,Viale G,Bachi A,Tripodo C,Scita G,Disanza A

更新日期：2020-07-14 00:00:00

abstract：:Layer-by-layer-stacked chemical vapour deposition (CVD) graphene films find applications as transparent and conductive electrodes in solar cells, organic light-emitting diodes and touch panels. Common to lamellar-type systems with anisotropic electron delocalization, the plane-to-plane (vertical) conductivity in such ...

journal_title：Nature communications

authors： Liu Y,Yuan L,Yang M,Zheng Y,Li L,Gao L,Nerngchamnong N,Nai CT,Sangeeth CS,Feng YP,Nijhuis CA,Loh KP

更新日期：2014-11-20 00:00:00

abstract：:Schwann cells (SCs) generate the myelin wrapping of peripheral nerve axons and are promising candidates for cell therapy. However, to date a renewable source of SCs is lacking. In this study, we show the conversion of skin fibroblasts into induced Schwann cells (iSCs) by driving the expression of two transcription fac...

journal_title：Nature communications

authors： Mazzara PG,Massimino L,Pellegatta M,Ronchi G,Ricca A,Iannielli A,Giannelli SG,Cursi M,Cancellieri C,Sessa A,Del Carro U,Quattrini A,Geuna S,Gritti A,Taveggia C,Broccoli V

更新日期：2017-02-07 00:00:00

abstract：:Noble metal nanoparticles stabilized by organic ligands are important for applications in assembly, site-specific bioconjugate labelling and sensing, drug delivery and medical therapy, molecular recognition and molecular electronics, and catalysis. Here we report crystal structures and theoretical analysis of three Ag...

journal_title：Nature communications

authors： Yang H,Wang Y,Huang H,Gell L,Lehtovaara L,Malola S,Häkkinen H,Zheng N

更新日期：2013-01-01 00:00:00

abstract：:Hypertension induces structural remodelling of arteries, which leads to arteriosclerosis and end-organ damage. Hyperplasia of vascular smooth muscle cells (VSMCs) and infiltration of immune cells are the hallmark of hypertensive arterial remodelling. However, the precise molecular mechanisms of arterial remodelling re...

journal_title：Nature communications

authors： Sumida T,Naito AT,Nomura S,Nakagawa A,Higo T,Hashimoto A,Okada K,Sakai T,Ito M,Yamaguchi T,Oka T,Akazawa H,Lee JK,Minamino T,Offermanns S,Noda T,Botto M,Kobayashi Y,Morita H,Manabe I,Nagai T,Shiojima I,Komuro

更新日期：2015-02-26 00:00:00

abstract：:Although the amyloid β-protein (Aβ) is believed to play an initiating role in Alzheimer's disease (AD), the molecular characteristics of the key pathogenic Aβ forms are not well understood. As a result, it has proved difficult to identify optimal agents that target disease-relevant forms of Aβ. Here, we combined the u...

journal_title：Nature communications

authors： Jin M,O'Nuallain B,Hong W,Boyd J,Lagomarsino VN,O'Malley TT,Liu W,Vanderburg CR,Frosch MP,Young-Pearse T,Selkoe DJ,Walsh DM

更新日期：2018-07-11 00:00:00

abstract：:Culture (behaviour based on socially transmitted information) is present in diverse animal species, yet how it interacts with genetic evolution remains largely unexplored. Here, we review the evidence for gene-culture coevolution in animals, especially birds, cetaceans and primates. We describe how culture can relax o...

journal_title：Nature communications

authors： Whitehead H,Laland KN,Rendell L,Thorogood R,Whiten A

更新日期：2019-06-03 00:00:00

abstract：:Free-electron lasers providing ultra-short high-brightness pulses of X-ray radiation have great potential for a wide impact on science, and are a critical element for unravelling the structural dynamics of matter. To fully harness this potential, we must accurately know the X-ray properties: intensity, spectrum and te...

journal_title：Nature communications

authors： Sanchez-Gonzalez A,Micaelli P,Olivier C,Barillot TR,Ilchen M,Lutman AA,Marinelli A,Maxwell T,Achner A,Agåker M,Berrah N,Bostedt C,Bozek JD,Buck J,Bucksbaum PH,Montero SC,Cooper B,Cryan JP,Dong M,Feifel R,Frasinski

更新日期：2017-06-05 00:00:00

abstract：:Wild boar (Sus scrofa) drastically colonized mainland Eurasia and North Africa, most likely from East Asia during the Plio-Pleistocene (2-1Mya). In recent studies, based on genome-wide information, it was hypothesized that wild boar did not replace the species it encountered, but instead exchanged genetic materials wi...

journal_title：Nature communications

authors： Liu L,Bosse M,Megens HJ,Frantz LAF,Lee YL,Irving-Pease EK,Narayan G,Groenen MAM,Madsen O

更新日期：2019-04-30 00:00:00

abstract：:Seismic tomography provides unique constraints on the morphology, the deformation, and (indirectly) the rheology of subducting slabs. We use teleseismic double-difference P-wave tomography to image with unprecedented clarity the structural complexity of the Izu-Bonin slab. We resolve a tear in the slab in the mantle t...

journal_title：Nature communications

authors： Zhang H,Wang F,Myhill R,Guo H

更新日期：2019-03-21 00:00:00

abstract：:The formation of the HIV-1 core is the final step in the viral maturation pathway, resulting in the formation of infectious virus. Most current models for HIV-1 core formation suggest that, upon proteolytic cleavage from the immature Gag, capsid (CA) dissociates into the viral interior before reforming into the core. ...

journal_title：Nature communications

authors： Frank GA,Narayan K,Bess JW Jr,Del Prete GQ,Wu X,Moran A,Hartnell LM,Earl LA,Lifson JD,Subramaniam S

更新日期：2015-01-08 00:00:00

abstract：:Acetic acid is an important bulk chemical that is currently produced via methanol carbonylation using fossil based CO. Synthesis of acetic acid from the renewable and cheap CO2 is of great importance, but state of the art routes encounter difficulties, especially in reaction selectivity and activity. Here we report a ...

journal_title：Nature communications

authors： Qian Q,Zhang J,Cui M,Han B

更新日期：2016-05-11 00:00:00

abstract：:Optical tracking is often combined with conventional flat panel solar cells to maximize electrical power generation over the course of a day. However, conventional trackers are complex and often require costly and cumbersome structural components to support system weight. Here we use kirigami (the art of paper cutting...

journal_title：Nature communications

authors： Lamoureux A,Lee K,Shlian M,Forrest SR,Shtein M

更新日期：2015-09-08 00:00:00

abstract：:Transforming growth factor-β (TGF-β) signaling and microRNAs (miRNAs) are important gene regulatory components in cancer. Usually in advanced malignant stages, TGF-β signaling is elevated but global miRNA expression is suppressed. Such a gene expression signature is well illustrated in a fibrosis (or mesenchymal) subt...

journal_title：Nature communications

authors： Ahn JH,Lee HS,Lee JS,Lee YS,Park JL,Kim SY,Hwang JA,Kunkeaw N,Jung SY,Kim TJ,Lee KS,Jeon SH,Lee I,Johnson BH,Choi JH,Lee YS

更新日期：2018-03-21 00:00:00

abstract：:Arriving rapidly to the hospital after a heart attack or stroke is critical for patients to be within time windows for treatment. Prior research in heart attacks has suggested a paradoxical role of the social environment: those who arrive early are surrounded by nonrelatives, while those who arrive late are surrounded...

journal_title：Nature communications

authors： Dhand A,Luke D,Lang C,Tsiaklides M,Feske S,Lee JM

更新日期：2019-03-14 00:00:00

abstract：:Determining nanoscale protein distribution via Photoactivated Localization Microscopy (PALM) mandates precise knowledge of the applied fluorophore's blinking properties to counteract overcounting artifacts that distort the resulting biomolecular distributions. Here, we present a readily applicable methodology to deter...

journal_title：Nature communications

authors： Platzer R,Rossboth BK,Schneider MC,Sevcsik E,Baumgart F,Stockinger H,Schütz GJ,Huppa JB,Brameshuber M

更新日期：2020-10-05 00:00:00

abstract：:Alkaline-urea aqueous solvent system provides a novel and important approach for the utilization of polysaccharide. As one of the most important polysaccharide, chitosan can be well dissolved in this solvent system, and the resultant hydrogel material possesses unique and excellent properties. Thus the sound understan...

journal_title：Nature communications

authors： Wang Z,Nie J,Qin W,Hu Q,Tang BZ

更新日期：2016-06-23 00:00:00

abstract：:In the original version of this Article, the affiliation details for Antoine Aze, Michalis Fragkos, Stéphane Bocquet, Julien Cau and Marcel Méchali incorrectly omitted 'CNRS and the University of Montpellier'. This has now been corrected in both the PDF and HTML versions of the Article. ...

journal_title：Nature communications

authors： Aze A,Fragkos M,Bocquet S,Cau J,Méchali M

更新日期：2018-02-05 00:00:00