Author Correction: RNAs coordinate nuclear envelope assembly and DNA replication through ELYS recruitment to chromatin.

abstract：:Hypoxia is a main driver of sprouting angiogenesis, but how tip endothelial cells are directed to hypoxic regions remains poorly understood. Here, we show that an endothelial MST1-FOXO1 cascade is essential for directional migration of tip cells towards hypoxic regions. In mice, endothelial-specific deletion of either...

journal_title：Nature communications

authors： Kim YH,Choi J,Yang MJ,Hong SP,Lee CK,Kubota Y,Lim DS,Koh GY

更新日期：2019-02-19 00:00:00

abstract：:Voltage control of magnetism in ferromagnetic semiconductor has emerged as an appealing solution to significantly reduce the power dissipation and variability beyond current CMOS technology. However, it has been proven to be very challenging to achieve a candidate with high Curie temperature (Tc), controllable ferroma...

journal_title：Nature communications

authors： Nie T,Tang J,Kou X,Gen Y,Lee S,Zhu X,He Q,Chang LT,Murata K,Fan Y,Wang KL

更新日期：2016-10-20 00:00:00

abstract：:Hutchinson-Gilford Progeria Syndrome (HGPS) is a premature aging disease in children that leads to early death. Smooth muscle cells (SMCs) are the most affected cells in HGPS individuals, although the reason for such vulnerability remains poorly understood. In this work, we develop a microfluidic chip formed by HGPS-S...

journal_title：Nature communications

authors： Pitrez PR,Estronca L,Monteiro LM,Colell G,Vazão H,Santinha D,Harhouri K,Thornton D,Navarro C,Egesipe AL,Carvalho T,Dos Santos RL,Lévy N,Smith JC,de Magalhães JP,Ori A,Bernardo A,De Sandre-Giovannoli A,Nissan X,Rosel

更新日期：2020-08-17 00:00:00

abstract：:Type 2 diabetes (T2D) results from the combined effects of genetic and environmental factors on multiple tissues over time. Of the >100 variants associated with T2D and related traits in genome-wide association studies (GWAS), >90% occur in non-coding regions, suggesting a strong regulatory component to T2D risk. Here...

journal_title：Nature communications

authors： Scott LJ,Erdos MR,Huyghe JR,Welch RP,Beck AT,Wolford BN,Chines PS,Didion JP,Narisu N,Stringham HM,Taylor DL,Jackson AU,Vadlamudi S,Bonnycastle LL,Kinnunen L,Saramies J,Sundvall J,Albanus RD,Kiseleva A,Hensley J,Cr

更新日期：2016-06-29 00:00:00

abstract：:Age, as a threshold of floral competence acquisition, prevents precocious flowering when there is insufficient biomass, and ensures flowering independent of environmental conditions; however, the underlying regulatory mechanisms are largely unknown. In this study, silencing the expression of a nuclear factor gene, CmN...

journal_title：Nature communications

authors： Wei Q,Ma C,Xu Y,Wang T,Chen Y,Lü J,Zhang L,Jiang CZ,Hong B,Gao J

更新日期：2017-10-10 00:00:00

abstract：:Repeat-associated non-AUG (RAN) translation allows for unconventional initiation at disease-causing repeat expansions. As RAN translation contributes to pathogenesis in multiple neurodegenerative disorders, determining its mechanistic underpinnings may inform therapeutic development. Here we analyze RAN translation at...

journal_title：Nature communications

authors： Green KM,Glineburg MR,Kearse MG,Flores BN,Linsalata AE,Fedak SJ,Goldstrohm AC,Barmada SJ,Todd PK

更新日期：2017-12-08 00:00:00

abstract：:Alternative splicing and alternative polyadenylation (APA) of pre-mRNAs greatly contribute to transcriptome diversity, coding capacity of a genome and gene regulatory mechanisms in eukaryotes. Second-generation sequencing technologies have been extensively used to analyse transcriptomes. However, a major limitation of...

journal_title：Nature communications

authors： Abdel-Ghany SE,Hamilton M,Jacobi JL,Ngam P,Devitt N,Schilkey F,Ben-Hur A,Reddy AS

更新日期：2016-06-24 00:00:00

abstract：:The modern energy economy and environmental infrastructure rely on the flow of fluids through fractures in rock. Yet this flow cannot be imaged directly because rocks are opaque to most probes. Here we apply chattering dust, or chemically reactive grains of sucrose containing pockets of pressurized carbon dioxide, to ...

journal_title：Nature communications

authors： Pyrak-Nolte LJ,Braverman W,Nolte NJ,Wright AJ,Nolte DD

更新日期：2020-10-19 00:00:00

abstract：:Long-read sequencing technologies have greatly facilitated assemblies of large eukaryotic genomes. In this paper, Oxford Nanopore sequences generated on a MinION sequencer are combined with Bionano Genomics Direct Label and Stain (DLS) optical maps to generate a chromosome-scale de novo assembly of the repeat-rich Sor...

journal_title：Nature communications

authors： Deschamps S,Zhang Y,Llaca V,Ye L,Sanyal A,King M,May G,Lin H

更新日期：2018-11-19 00:00:00

abstract：:Polycomb repressive complex 2 (PRC2) controls maintenance and lineage determination of stem cells by suppressing genes that regulate cellular differentiation and tissue development. However, the role of PRC2 in lineage-committed somatic cells is mostly unknown. Here we show that Eed deficiency in chondrocytes causes s...

journal_title：Nature communications

authors： Mirzamohammadi F,Papaioannou G,Inloes JB,Rankin EB,Xie H,Schipani E,Orkin SH,Kobayashi T

更新日期：2016-06-22 00:00:00

abstract：:Genetic heterogeneity between and within tumours is a major factor determining cancer progression and therapy response. Here we examined DNA sequence and DNA copy-number heterogeneity in colorectal cancer (CRC) by targeted high-depth sequencing of 100 most frequently altered genes. In 97 samples, with primary tumours ...

journal_title：Nature communications

authors： Mamlouk S,Childs LH,Aust D,Heim D,Melching F,Oliveira C,Wolf T,Durek P,Schumacher D,Bläker H,von Winterfeld M,Gastl B,Möhr K,Menne A,Zeugner S,Redmer T,Lenze D,Tierling S,Möbs M,Weichert W,Folprecht G,Blanc E,

更新日期：2017-01-25 00:00:00

abstract：:A universally accepted explanation for why liquids sometimes vitrify rather than crystallize remains hotly pursued, despite the ubiquity of glass in our everyday lives, the utilization of the glass transition in innumerable modern technologies, and nearly a century of theoretical and experimental investigation. Among ...

journal_title：Nature communications

authors： Teich EG,van Anders G,Glotzer SC

更新日期：2019-01-08 00:00:00

abstract：:Secondary multidrug transporters use ion concentration gradients to energize the removal from cells of various antibiotics. The Escherichia coli multidrug transporter MdfA exchanges a single proton with a single monovalent cationic drug molecule. This stoichiometry renders the efflux of divalent cationic drugs energet...

journal_title：Nature communications

authors： Fluman N,Adler J,Rotenberg SA,Brown MH,Bibi E

更新日期：2014-08-08 00:00:00

abstract：:Human pressures on the ocean are thought to be increasing globally, yet we know little about their patterns of cumulative change, which pressures are most responsible for change, and which places are experiencing the greatest increases. Managers and policymakers require such information to make strategic decisions and...

journal_title：Nature communications

authors： Halpern BS,Frazier M,Potapenko J,Casey KS,Koenig K,Longo C,Lowndes JS,Rockwood RC,Selig ER,Selkoe KA,Walbridge S

更新日期：2015-07-14 00:00:00

abstract：:Fusion proteins containing blue-light-activable protein domains possess great potential as molecular switches in cell signalling. This has recently been impressively demonstrated by connecting the light oxygen voltage LOV2-Jα-protein domain of A. sativa (AsLOV2-Jα) with the Rac1-GTPase, responsible for regulating the ...

journal_title：Nature communications

authors： Peter E,Dick B,Baeurle SA

更新日期：2010-11-16 00:00:00

abstract：:It is unclear why atmospheric oxygen remained trapped at low levels for more than 1.5 billion years following the Paleoproterozoic Great Oxidation Event. Here, we use models for erosion, weathering and biogeochemical cycling to show that this can be explained by the tectonic recycling of previously accumulated sedimen...

journal_title：Nature communications

authors： Daines SJ,Mills BJ,Lenton TM

更新日期：2017-02-02 00:00:00

abstract：:Directed self-assemblies in water are known as the most efficient means of forming complex higher ordered structures in nature. Here we show a straightforward and robust method for particle assembly which utilises the amphiphilic tri-block co-polymer poloxamer-188 and a hydrophobic fluorophore as the two designer comp...

journal_title：Nature communications

authors： Cheung S,O'Shea DF

更新日期：2017-12-01 00:00:00

abstract：:Plasmid-borne colistin resistance mediated by mcr-1 may contribute to the dissemination of pan-resistant Gram-negative bacteria. Here, we show that mcr-1 confers resistance to colistin-induced lysis and bacterial cell death, but provides minimal protection from the ability of colistin to disrupt the Gram-negative oute...

journal_title：Nature communications

authors： MacNair CR,Stokes JM,Carfrae LA,Fiebig-Comyn AA,Coombes BK,Mulvey MR,Brown ED

更新日期：2018-01-31 00:00:00

abstract：:Practice improves perception and enhances neural representations of trained visual stimuli, a phenomenon known as visual perceptual learning (VPL). While attention to task-relevant stimuli plays an important role in such learning, Pavlovian stimulus-reinforcer associations are sufficient to drive VPL, even subconsciou...

journal_title：Nature communications

authors： Arsenault JT,Vanduffel W

更新日期：2019-08-09 00:00:00

abstract：:Oligodendrocytes (OLs) are the myelin-forming cells of the central nervous system. They are derived from differentiation of oligodendrocyte progenitors through a process requiring cell cycle exit and histone modifications. Here we identify the histone arginine methyl-transferase PRMT5, a molecule catalyzing symmetric ...

journal_title：Nature communications

authors： Scaglione A,Patzig J,Liang J,Frawley R,Bok J,Mela A,Yattah C,Zhang J,Teo SX,Zhou T,Chen S,Bernstein E,Canoll P,Guccione E,Casaccia P

更新日期：2018-07-19 00:00:00

abstract：:ATAC-seq has become a leading technology for probing the chromatin landscape of single and aggregated cells. Distilling functional regions from ATAC-seq presents diverse analysis challenges. Methods commonly used to analyze chromatin accessibility datasets are adapted from algorithms designed to process different expe...

journal_title：Nature communications

authors： Gabitto MI,Rasmussen A,Wapinski O,Allaway K,Carriero N,Fishell GJ,Bonneau R

更新日期：2020-02-06 00:00:00

abstract：:In the Drosophila antenna, different subtypes of olfactory receptor neurons (ORNs) housed in the same sensory hair (sensillum) can inhibit each other non-synaptically. However, the mechanisms underlying this underexplored form of lateral inhibition remain unclear. Here we use recordings from pairs of sensilla impaled ...

journal_title：Nature communications

authors： Zhang Y,Tsang TK,Bushong EA,Chu LA,Chiang AS,Ellisman MH,Reingruber J,Su CY

更新日期：2019-04-05 00:00:00

abstract：:Formation of amyloid-beta (Aβ) oligomer pores in the membrane of neurons has been proposed to explain neurotoxicity in Alzheimer's disease (AD). Here, we present the three-dimensional structure of an Aβ oligomer formed in a membrane mimicking environment, namely an Aβ(1-42) tetramer, which comprises a six stranded β-s...

journal_title：Nature communications

authors： Ciudad S,Puig E,Botzanowski T,Meigooni M,Arango AS,Do J,Mayzel M,Bayoumi M,Chaignepain S,Maglia G,Cianferani S,Orekhov V,Tajkhorshid E,Bardiaux B,Carulla N

更新日期：2020-06-15 00:00:00

abstract：:Preparation and characterization of polariton Bose-Einstein condensates in micro-cavities of high quality are at the frontier of contemporary solid state physics. Here, we report on three-dimensional polariton condensation and confinement in pseudo-spherical ZnO microcrystals. The boundary of micro-spherical ZnO resem...

journal_title：Nature communications

authors： Volkov VV,Oliver DJ,Perry CC

更新日期：2020-09-30 00:00:00

abstract：:Understanding lithospheric plate motions is of paramount importance to geodynamicists. Much effort is going into kinematic reconstructions featuring progressively finer temporal resolution. However, the challenge of precisely identifying ocean-floor magnetic lineations, and uncertainties in geomagnetic reversal timesc...

journal_title：Nature communications

authors： Iaffaldano G,Bodin T,Sambridge M

更新日期：2012-01-01 00:00:00

abstract：:The worldwide incidence of pulmonary carcinoids is increasing, but little is known about their molecular characteristics. Through machine learning and multi-omics factor analysis, we compare and contrast the genomic profiles of 116 pulmonary carcinoids (including 35 atypical), 75 large-cell neuroendocrine carcinomas (...

journal_title：Nature communications

authors： Alcala N,Leblay N,Gabriel AAG,Mangiante L,Hervas D,Giffon T,Sertier AS,Ferrari A,Derks J,Ghantous A,Delhomme TM,Chabrier A,Cuenin C,Abedi-Ardekani B,Boland A,Olaso R,Meyer V,Altmuller J,Le Calvez-Kelm F,Durand G,V

更新日期：2019-08-20 00:00:00

abstract：:Translocating proteins across the double membrane of Gram-negative bacteria, type III secretion systems (T3SS) occur in two evolutionarily related forms: injectisomes, delivering virulence factors into host cells, and the flagellar system, secreting the polymeric filament used for motility. While both systems share re...

journal_title：Nature communications

authors： Notti RQ,Bhattacharya S,Lilic M,Stebbins CE

更新日期：2015-05-21 00:00:00

abstract：:Respiratory syncytial virus (RSV) causes acute lower respiratory tract infections and is the leading cause of infant hospitalizations. Recently, a promising vaccine antigen based on the RSV fusion protein (RSV F) stabilized in the native prefusion conformation has been described. Here we report alternative strategies ...

journal_title：Nature communications

authors： Krarup A,Truan D,Furmanova-Hollenstein P,Bogaert L,Bouchier P,Bisschop IJM,Widjojoatmodjo MN,Zahn R,Schuitemaker H,McLellan JS,Langedijk JPM

更新日期：2015-09-03 00:00:00

abstract：:An evolutionary account of human language as a neurobiological system must distinguish between human-unique neurocognitive processes supporting language and evolutionarily conserved, domain-general processes that can be traced back to our primate ancestors. Neuroimaging studies across species may determine whether can...

journal_title：Nature communications

authors： Wilson B,Kikuchi Y,Sun L,Hunter D,Dick F,Smith K,Thiele A,Griffiths TD,Marslen-Wilson WD,Petkov CI

更新日期：2015-11-17 00:00:00

abstract：:The original version of this Article contained an error in the spelling of the author Jianyun Yan, which was incorrectly given as Jiangyun Yan. This has now been corrected in both the PDF and HTML versions of the Article. ...

journal_title：Nature communications

authors： Zhang D,Wang Y,Lu P,Wang P,Yuan X,Yan J,Cai C,Chang CP,Zheng D,Wu B,Zhou B

更新日期：2018-01-12 00:00:00