Polariton condensation and surface enhanced Raman in spherical ZnO microcrystals.

abstract：:ADAM17, a prominent member of the 'Disintegrin and Metalloproteinase' (ADAM) family, controls vital cellular functions through cleavage of transmembrane substrates. Here we present evidence that surface exposure of phosphatidylserine (PS) is pivotal for ADAM17 to exert sheddase activity. PS exposure is tightly coupled...

journal_title：Nature communications

authors： Sommer A,Kordowski F,Büch J,Maretzky T,Evers A,Andrä J,Düsterhöft S,Michalek M,Lorenzen I,Somasundaram P,Tholey A,Sönnichsen FD,Kunzelmann K,Heinbockel L,Nehls C,Gutsmann T,Grötzinger J,Bhakdi S,Reiss K

更新日期：2016-05-10 00:00:00

abstract：:Nociceptors rely on cap-dependent translation to rapidly induce protein synthesis in response to pro-inflammatory signals. Comparatively little is known regarding the role of the regulatory factors bound to the 3' end of mRNA in nociceptor sensitization. Poly(A)-binding protein (PABP) stimulates translation initiation...

journal_title：Nature communications

authors： Barragán-Iglesias P,Lou TF,Bhat VD,Megat S,Burton MD,Price TJ,Campbell ZT

更新日期：2018-01-02 00:00:00

abstract：:The phosphorylation of eIF4E1 at serine 209 by MNK1 or MNK2 has been shown to initiate oncogenic mRNA translation, a process that favours cancer development and maintenance. Here, we interrogate the MNK-eIF4E axis in diffuse large B-cell lymphoma (DLBCL) and show a distinct distribution of MNK1 and MNK2 in germinal ce...

journal_title：Nature communications

authors： Landon AL,Muniandy PA,Shetty AC,Lehrmann E,Volpon L,Houng S,Zhang Y,Dai B,Peroutka R,Mazan-Mamczarz K,Steinhardt J,Mahurkar A,Becker KG,Borden KL,Gartenhaus RB

更新日期：2014-11-18 00:00:00

abstract：:The original version of this Article contained an error in the spelling of the author Álvaro Sebastián-Serrano, which was incorrectly given as Álvaro Sebastián Serrano. This has now been corrected in both the PDF and HTML versions of the Article. ...

journal_title：Nature communications

authors： Pose-Utrilla J,García-Guerra L,Del Puerto A,Martín A,Jurado-Arjona J,De León-Reyes NS,Gamir-Morralla A,Sebastián-Serrano Á,García-Gallo M,Kremer L,Fielitz J,Ireson C,Pérez-Álvarez MJ,Ferrer I,Hernández F,Ávila J,Lasa M,

更新日期：2018-01-30 00:00:00

abstract：:Metal ions at the active site of an enzyme act as cofactors, and their dynamic fluctuations can potentially influence enzyme activity. Here, we use λ-exonuclease as a model enzyme with two Mg2+ binding sites and probe activity at various concentrations of magnesium by single-molecule-FRET. We find that while MgA2+ and...

journal_title：Nature communications

authors： Hwang W,Yoo J,Lee Y,Park S,Hoang PL,Cho H,Yu J,Hoa Vo TM,Shin M,Jin MS,Park D,Hyeon C,Lee G

更新日期：2018-10-23 00:00:00

abstract：:Selector devices are indispensable components of large-scale nonvolatile memory and neuromorphic array systems. Besides the conventional silicon transistor, two-terminal ovonic threshold switching device with much higher scalability is currently the most industrially favored selector technology. However, current ovoni...

journal_title：Nature communications

authors： Jia S,Li H,Gotoh T,Longeaud C,Zhang B,Lyu J,Lv S,Zhu M,Song Z,Liu Q,Robertson J,Liu M

更新日期：2020-09-15 00:00:00

abstract：:Ganglioside GM3, a host-derived glycosphingolipid incorporated in the membrane of human immunodeficiency virus-1 (HIV-1) viral particles, mediates interactions between HIV-1 and Siglec1/CD169, a protein expressed on dendritic cells (DCs). Such interactions, which seem to be independent of viral envelope glycoprotein g...

journal_title：Nature communications

authors： Yu X,Feizpour A,Ramirez NG,Wu L,Akiyama H,Xu F,Gummuluru S,Reinhard BM

更新日期：2014-06-20 00:00:00

abstract：:The capsaicin receptor TRPV1 has been intensively studied by cryo-electron microscopy and functional tests. However, though the apo and capsaicin-bound structural models are available, the dynamic process of capsaicin activation remains intangible, largely due to the lack of a capsaicin-induced open structural model a...

journal_title：Nature communications

authors： Yang F,Xiao X,Lee BH,Vu S,Yang W,Yarov-Yarovoy V,Zheng J

更新日期：2018-07-23 00:00:00

abstract：:Bright solitons are non-dispersive wave solutions, arising in a diverse range of nonlinear, one-dimensional systems, including atomic Bose-Einstein condensates with attractive interactions. In reality, cold-atom experiments can only approach the idealized one-dimensional limit necessary for the realization of true sol...

journal_title：Nature communications

authors： Marchant AL,Billam TP,Wiles TP,Yu MM,Gardiner SA,Cornish SL

更新日期：2013-01-01 00:00:00

abstract：:We establish a powerful poly(4-styrenesulfonate) (PSS)-treated strategy for sulfur vacancy healing in monolayer MoS2 to precisely and steadily tune its electronic state. The self-healing mechanism, in which the sulfur vacancies are healed spontaneously by the sulfur adatom clusters on the MoS2 surface through a PSS-in...

journal_title：Nature communications

authors： Zhang X,Liao Q,Liu S,Kang Z,Zhang Z,Du J,Li F,Zhang S,Xiao J,Liu B,Ou Y,Liu X,Gu L,Zhang Y

更新日期：2017-06-22 00:00:00

abstract：:Since the 1970s, it has been known that black-hole (and other) horizons are truly thermodynamic. More generally, surfaces which are not horizons have also been conjectured to behave thermodynamically. Initially, for surfaces microscopically expanded from a horizon to so-called stretched horizons, and more recently, fo...

journal_title：Nature communications

authors： Wang ZW,Braunstein SL

更新日期：2018-07-30 00:00:00

abstract：:A crumpled sheet of paper displays an intricate pattern of creases and point-like singular structures, termed d-cones. It is typically assumed that elongated creases form when ridges connecting two d-cones fold beyond the material yielding threshold, and scarring is thus a by-product of the folding dynamics that seek ...

journal_title：Nature communications

authors： Gottesman O,Efrati E,Rubinstein SM

更新日期：2015-06-11 00:00:00

abstract：:It is known that granulosa cells (GCs) mediate gonadotropin-induced oocyte meiosis resumption by releasing EGF-like factors in mammals, however, the detailed molecular mechanisms remain unclear. Here, we demonstrate that luteinizing hormone (LH) surge-induced histone deacetylase 3 (HDAC3) downregulation in GCs is esse...

journal_title：Nature communications

authors： Wang H,Cai H,Wang X,Zhang M,Liu B,Chen Z,Yang T,Fang J,Zhang Y,Liu W,Han J,Guo Q,Zhang H,Wang H,Xia G,Wang C

更新日期：2019-12-16 00:00:00

abstract：:Spinocerebellar ataxia type 5 (SCA5) is a neurodegenerative disease caused by mutations in the cytoskeletal protein β-III-spectrin. Previously, a SCA5 mutation resulting in a leucine-to-proline substitution (L253P) in the actin-binding domain (ABD) was shown to cause a 1000-fold increase in actin-binding affinity. How...

journal_title：Nature communications

authors： Avery AW,Fealey ME,Wang F,Orlova A,Thompson AR,Thomas DD,Hays TS,Egelman EH

更新日期：2017-11-07 00:00:00

abstract：:In photosystem II, light-induced water oxidation occurs at the Mn4CaO5 cluster. Here we demonstrate proton releases, dioxygen formation, and substrate water incorporation in response to Mn4CaO5 oxidation in the protein environment, using a quantum mechanical/molecular mechanical approach and molecular dynamics simulat...

journal_title：Nature communications

authors： Kawashima K,Takaoka T,Kimura H,Saito K,Ishikita H

更新日期：2018-03-28 00:00:00

abstract：:How stem cells give rise to epidermis is unclear despite the crucial role the epidermis plays in barrier and appendage formation. Here we use single cell-RNA sequencing to interrogate basal stem cell heterogeneity of human interfollicular epidermis and find four spatially distinct stem cell populations at the top and ...

journal_title：Nature communications

authors： Wang S,Drummond ML,Guerrero-Juarez CF,Tarapore E,MacLean AL,Stabell AR,Wu SC,Gutierrez G,That BT,Benavente CA,Nie Q,Atwood SX

更新日期：2020-08-25 00:00:00

abstract：:Symmetry and topology are two fundamental aspects of many quantum states of matter. Recently new topological materials, higher-order topological insulators, were discovered, featuring bulk-edge-corner correspondence that goes beyond the conventional topological paradigms. Here we discover experimentally that the nonsy...

journal_title：Nature communications

authors： Zhang X,Lin ZK,Wang HX,Xiong Z,Tian Y,Lu MH,Chen YF,Jiang JH

更新日期：2020-01-03 00:00:00

abstract：:Multiferroic bismuth ferrite, BiFeO3, offers a vast landscape to study the interplay between different ferrroic orders. Another aspect which is equally exciting, and yet underutilized, is the possibility of large-scale ordering of domains. Along with symmetry-driven bulk photovoltaic effect, BiFeO3 presents opportunit...

journal_title：Nature communications

authors： Knoche DS,Steimecke M,Yun Y,Mühlenbein L,Bhatnagar A

更新日期：2021-01-12 00:00:00

abstract：:Modern ultrafast metrology relies on the postulate that the pulse to be measured is fully coherent, that is, that it can be completely described by its spectrum and spectral phase. However, synthesizing fully coherent pulses is not always possible in practice, especially in the domain of emerging ultrashort X-ray sour...

journal_title：Nature communications

authors： Bourassin-Bouchet C,Couprie ME

更新日期：2015-03-06 00:00:00

abstract：:Long nanopore reads are advantageous in de novo genome assembly. However, nanopore reads usually have broad error distribution and high-error-rate subsequences. Existing error correction tools cannot correct nanopore reads efficiently and effectively. Most methods trim high-error-rate subsequences during error correct...

journal_title：Nature communications

authors： Chen Y,Nie F,Xie SQ,Zheng YF,Dai Q,Bray T,Wang YX,Xing JF,Huang ZJ,Wang DP,He LJ,Luo F,Wang JX,Liu YZ,Xiao CL

更新日期：2021-01-04 00:00:00

abstract：:Quantum metrology bears a great promise in enhancing measurement precision, but is unlikely to become practical in the near future. Its concepts can nevertheless inspire classical or hybrid methods of immediate value. Here we demonstrate NOON-like photonic states of m quanta of angular momentum up to m=100, in a setup...

journal_title：Nature communications

authors： D'Ambrosio V,Spagnolo N,Del Re L,Slussarenko S,Li Y,Kwek LC,Marrucci L,Walborn SP,Aolita L,Sciarrino F

更新日期：2013-01-01 00:00:00

abstract：:Oligodendrocytes (OLs) are the myelin-forming cells of the central nervous system. They are derived from differentiation of oligodendrocyte progenitors through a process requiring cell cycle exit and histone modifications. Here we identify the histone arginine methyl-transferase PRMT5, a molecule catalyzing symmetric ...

journal_title：Nature communications

authors： Scaglione A,Patzig J,Liang J,Frawley R,Bok J,Mela A,Yattah C,Zhang J,Teo SX,Zhou T,Chen S,Bernstein E,Canoll P,Guccione E,Casaccia P

更新日期：2018-07-19 00:00:00

abstract：:A phase transition is often accompanied by the appearance of an order parameter and symmetry breaking. Certain magnetic materials exhibit exotic hidden-order phases, in which the order parameters are not directly accessible to conventional magnetic measurements. Thus, experimental identification and theoretical unders...

journal_title：Nature communications

authors： Shen Y,Liu C,Qin Y,Shen S,Li YD,Bewley R,Schneidewind A,Chen G,Zhao J

更新日期：2019-10-08 00:00:00

abstract：:A Weyl semimetal possesses spin-polarized band-crossings, called Weyl nodes, connected by topological surface arcs. The low-energy excitations near the crossing points behave the same as massless Weyl fermions, leading to exotic properties like chiral anomaly. To have the transport properties dominated by Weyl fermion...

journal_title：Nature communications

authors： Xu N,Weng HM,Lv BQ,Matt CE,Park J,Bisti F,Strocov VN,Gawryluk D,Pomjakushina E,Conder K,Plumb NC,Radovic M,Autès G,Yazyev OV,Fang Z,Dai X,Qian T,Mesot J,Ding H,Shi M

更新日期：2016-03-17 00:00:00

abstract：:Exfoliated two-dimensional (2D) sheets can readily stack to form flexible, free-standing films with lamellar microstructure. The interlayer spaces in such lamellar films form a percolated network of molecularly sized, 2D nanochannels that could be used to regulate molecular transport. Here we report self-assembled cla...

journal_title：Nature communications

authors： Shao JJ,Raidongia K,Koltonow AR,Huang J

更新日期：2015-07-13 00:00:00

abstract：:Semiconductor-based surface-enhanced Raman spectroscopy (SERS) substrates represent a new frontier in the field of SERS. However, the application of semiconductor materials as SERS substrates is still seriously impeded by their low SERS enhancement and inferior detection sensitivity, especially for non-metal-oxide sem...

journal_title：Nature communications

authors： Zheng Z,Cong S,Gong W,Xuan J,Li G,Lu W,Geng F,Zhao Z

更新日期：2017-12-08 00:00:00

abstract：:Poly-(ADP-ribose) polymerase inhibitors (PARPi) selectively kill breast and ovarian cancers with defects in homologous recombination (HR) caused by BRCA1/2 mutations. There is also clinical evidence for the utility of PARPi in breast and ovarian cancers without BRCA mutations, but the underlying mechanism is not clear...

journal_title：Nature communications

authors： Peng Y,Liao Q,Tan W,Peng C,Hu Z,Chen Y,Li Z,Li J,Zhen B,Zhu W,Li X,Yao Y,Song Q,Liu C,Qi X,He F,Pei H

更新日期：2019-03-15 00:00:00

abstract：:Osteoarthritis (OA), primarily characterized by articular cartilage destruction, is the most common form of age-related degenerative whole-joint disease. No disease-modifying treatments for OA are currently available. Although OA is primarily characterized by cartilage destruction, our understanding of the processes c...

journal_title：Nature communications

authors： Park DR,Kim J,Kim GM,Lee H,Kim M,Hwang D,Lee H,Kim HS,Kim W,Park MC,Shim H,Lee SY

更新日期：2020-08-28 00:00:00

abstract：:DNA-coated colloids hold great promise for self-assembly of programmed heterogeneous microstructures, provided they not only bind when cooled below their melting temperature, but also rearrange so that aggregated particles can anneal into the structure that minimizes the free energy. Unfortunately, DNA-coated colloids...

journal_title：Nature communications

authors： Wang Y,Wang Y,Zheng X,Ducrot É,Yodh JS,Weck M,Pine DJ

更新日期：2015-06-16 00:00:00

abstract：:Two hundred years ago, Ampère discovered that electric loops in which currents of electrons are generated by a penetrating magnetic field can mutually interact. Here we show that Ampère's observation can be transferred to the quantum realm of interactions between triangular plaquettes of spins on a lattice, where the ...

journal_title：Nature communications

authors： Grytsiuk S,Hanke JP,Hoffmann M,Bouaziz J,Gomonay O,Bihlmayer G,Lounis S,Mokrousov Y,Blügel S

更新日期：2020-01-24 00:00:00