Abstract:
:A Weyl semimetal possesses spin-polarized band-crossings, called Weyl nodes, connected by topological surface arcs. The low-energy excitations near the crossing points behave the same as massless Weyl fermions, leading to exotic properties like chiral anomaly. To have the transport properties dominated by Weyl fermions, Weyl nodes need to locate nearly at the chemical potential and enclosed by pairs of individual Fermi surfaces with non-zero Fermi Chern numbers. Combining angle-resolved photoemission spectroscopy and first-principles calculation, here we show that TaP is a Weyl semimetal with only a single type of Weyl fermions, topologically distinguished from TaAs where two types of Weyl fermions contribute to the low-energy physical properties. The simple Weyl fermions in TaP are not only of fundamental interests but also of great potential for future applications. Fermi arcs on the Ta-terminated surface are observed, which appear in a different pattern from that on the As-termination in TaAs and NbAs.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Xu N,Weng HM,Lv BQ,Matt CE,Park J,Bisti F,Strocov VN,Gawryluk D,Pomjakushina E,Conder K,Plumb NC,Radovic M,Autès G,Yazyev OV,Fang Z,Dai X,Qian T,Mesot J,Ding H,Shi Mdoi
10.1038/ncomms11006subject
Has Abstractpub_date
2016-03-17 00:00:00pages
11006issn
2041-1723pii
ncomms11006journal_volume
7pub_type
杂志文章abstract::Mass extinctions have profoundly impacted the evolution of life through not only reducing taxonomic diversity but also reshaping ecosystems and biogeographic patterns. In particular, they are considered to have driven increased biogeographic cosmopolitanism, but quantitative tests of this hypothesis are rare and have ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-00827-7
更新日期:2017-10-10 00:00:00
abstract::HOXA9 and MEIS1 have essential oncogenic roles in mixed lineage leukaemia (MLL)-rearranged leukaemia. Here we show that they are direct targets of miRNA-196b, a microRNA (miRNA) located adjacent to and co-expressed with HOXA9, in MLL-rearranged leukaemic cells. Forced expression of miR-196b significantly delays MLL-fu...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1681
更新日期:2012-02-21 00:00:00
abstract::In fragmented forests, tree diversity declines near edges but the ecological processes underlying this loss of diversity remain poorly understood. Theory predicts that top-down regulation of seedling recruitment by insect herbivores and fungal pathogens contributes to maintaining tree diversity in forests, but it is u...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-06997-2
更新日期:2018-10-30 00:00:00
abstract::SMC (structural maintenance of chromosomes) family members play essential roles in chromosome condensation, sister chromatid cohesion and DNA repair. It remains unclear how SMCs structure chromosomes and how their mechanochemical cycle regulates their interactions with DNA. Here we used single-molecule fluorescence mi...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10200
更新日期:2016-01-04 00:00:00
abstract::Sensors using nitrogen-vacancy centers in diamond are a promising tool for small-volume nuclear magnetic resonance (NMR) spectroscopy, but the limited sensitivity remains a challenge. Here we show nearly two orders of magnitude improvement in concentration sensitivity over previous nitrogen-vacancy and picoliter NMR s...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-00266-4
更新日期:2017-08-04 00:00:00
abstract::Any experienced event may be encoded and retained in detail as part of our episodic memory, and may also refer and contribute to our generalized knowledge stored in semantic memory. The beginnings of this declarative memory formation are only poorly understood. Even less is known about the interrelation between episod...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-14850-8
更新日期:2020-03-10 00:00:00
abstract::Ubiquitylation of histone H2B at lysine residue 120 (H2BK120ub) is a prominent histone posttranslational modification (PTM) associated with the actively transcribed genome. Although H2BK120ub triggers several critical downstream histone modification pathways and changes in chromatin structure, less is known about the ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03895-5
更新日期:2018-04-11 00:00:00
abstract::Broomcorn millet (Panicum miliaceum L.) has strong tolerance to abiotic stresses, and is probably one of the oldest crops, with its earliest cultivation that dated back to ca. ~10,000 years. We report here its genome assembly through a combination of PacBio sequencing, BioNano, and Hi-C (in vivo) mapping. The 18 super...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-07876-6
更新日期:2019-01-25 00:00:00
abstract::Variation in the geographic spread of fossil localities strongly biases inferences about the evolution of biodiversity, due to the ubiquitous scaling of species richness with area. This obscures answers to key questions, such as how tetrapods attained their tremendous extant diversity. Here, we address this problem by...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms15381
更新日期:2017-05-22 00:00:00
abstract::Many cancer cells display enhanced glycolysis and suppressed mitochondrial metabolism. This phenomenon, known as the Warburg effect, is critical for tumor development. However, how cancer cells coordinate glucose metabolism through glycolysis and the mitochondrial tricarboxylic acid (TCA) cycle is largely unknown. We ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13601-8
更新日期:2020-01-07 00:00:00
abstract::Central nervous system (CNS) injuries persist for years, and currently there are no therapeutics that can address the complex injury cascade that develops over this time-scale. 17β-estradiol (E2) has broad tropism within the CNS, targeting and inducing beneficial phenotypic changes in myriad cells following injury. To...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-12835-w
更新日期:2019-10-23 00:00:00
abstract::Accumulation of mutant p53 proteins is frequently found in a wide range of cancers. While conventional antibodies fail to target intracellular proteins, proteosomal degradation results in the presentation of p53-derived peptides on the tumour cell surface by class I molecules of the major histocompatibility complex (M...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13305-z
更新日期:2019-11-26 00:00:00
abstract::HPV16 causes half of cervical cancers worldwide; for unknown reasons, most infections resolve within two years. Here, we analyze the viral genomes of 5,328 HPV16-positive case-control samples to investigate mutational signatures and the role of human APOBEC3-induced mutations in viral clearance and cervical carcinogen...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-14730-1
更新日期:2020-02-14 00:00:00
abstract::Mitochondrial DNA (mtDNA) deletions are associated with mitochondrial disease, and also accumulate during normal human ageing. The mechanisms underlying mtDNA deletions remain unknown although several models have been proposed. Here we use deep sequencing to characterize abundant mtDNA deletions in patients with mutat...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-08673-5
更新日期:2019-02-15 00:00:00
abstract::Benzoxaboroles are effective against bacterial, fungal and protozoan pathogens. We report potent activity of the benzoxaborole AN3661 against Plasmodium falciparum laboratory-adapted strains (mean IC50 32 nM), Ugandan field isolates (mean ex vivo IC50 64 nM), and murine P. berghei and P. falciparum infections (day 4 E...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms14574
更新日期:2017-03-06 00:00:00
abstract::Antibiotic biosynthetic gene clusters (BGCs) produce bioactive metabolites that impart a fitness advantage to their producer, providing a mechanism for natural selection. This selection drives antibiotic evolution and adapts BGCs for expression in different organisms, potentially providing clues to improve heterologou...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-18018-2
更新日期:2020-08-21 00:00:00
abstract::Highly specific Cas9 nucleases derived from SpCas9 are valuable tools for genome editing, but their wide applications are hampered by a lack of knowledge governing guide RNA (gRNA) activity. Here, we perform a genome-scale screen to measure gRNA activity for two highly specific SpCas9 variants (eSpCas9(1.1) and SpCas9...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-12281-8
更新日期:2019-09-19 00:00:00
abstract::A topological insulator is the state of quantum matter possessing gapless spin-locking surface states across the bulk band gap, which has created new opportunities from novel electronics to energy conversion. However, the large concentration of bulk residual carriers has been a major challenge for revealing the proper...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1771
更新日期:2012-03-27 00:00:00
abstract::RNA has emerged as a promising material for nanostructure and microstructure engineering. Although rare, some macroscopic RNA structures have also been constructed using lipid or polymer materials. Here, we report the first example of an enzymatically generated RNA membrane. This robust and free-standing RNA membrane ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms5367
更新日期:2014-07-04 00:00:00
abstract::Two-component signal transduction systems consist of pairs of histidine kinases and response regulators, which mediate adaptive responses to environmental cues. Most activated response regulators regulate transcription by binding tightly to promoter DNA via a phosphorylation-triggered inactive-to-active transition. Th...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms4282
更新日期:2014-01-01 00:00:00
abstract::Achieving control over the directionality of active colloids is essential for their use in practical applications such as cargo carriers in microfluidic devices. So far, guidance of spherical Janus colloids was mainly realized using specially engineered magnetic multilayer coatings combined with external magnetic fiel...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10598
更新日期:2016-02-09 00:00:00
abstract::Integrin αVβ8, which like αVβ6 functions to activate TGF-βs, is atypical. Its β8 subunit binds to a distinctive cytoskeleton adaptor and does not exhibit large changes in conformation upon binding to ligand. Here, crystal structures, hydrogen-deuterium exchange dynamics, and affinity measurements on mutants are used t...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13248-5
更新日期:2019-12-02 00:00:00
abstract::Mucosal associated invariant T (MAIT) cells recognise conserved microbial metabolites from riboflavin synthesis. Striking evolutionary conservation and pulmonary abundance implicate them in antibacterial host defence, yet their functions in protection against clinically important pathogens are unknown. Here we show th...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-05202-8
更新日期:2018-08-22 00:00:00
abstract::The novel coronavirus disease 2019 (COVID-19) was first reported in Wuhan, China, where the initial wave of intense community transmissions was cut short by interventions. Using multiple data sources, here we estimate the disease burden and clinical severity by age of COVID-19 in Wuhan from December 1, 2019 to March 3...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19238-2
更新日期:2020-10-27 00:00:00
abstract::Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus. Our understanding of PEL is poor and therefore treatment strategies are lacking. To address this need, we conducted genome-wide CRISPR/Cas9 knockout screens in eight PEL cell lines. Integration with data from unrelated cancers identi...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-05506-9
更新日期:2018-08-15 00:00:00
abstract::Mutations in many centriolar protein-encoding genes cause primary microcephaly. Using super-resolution and electron microscopy, we find that the human microcephaly protein, RTTN, is recruited to the proximal end of the procentriole at early S phase, and is located at the inner luminal walls of centrioles. Further stud...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-00305-0
更新日期:2017-08-15 00:00:00
abstract::The gravitational collapse of eruption columns generates ground-hugging pyroclastic density currents (PDCs) with highly variable temperatures, high enough to be a threat for communities surrounding volcanoes. The reasons for such great temperature variability are debated in terms of eruptive versus transport and empla...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-10337-3
更新日期:2019-06-06 00:00:00
abstract::Moonlighting proteins are a subclass of multifunctional proteins whose functions are unrelated. Although they may play important roles in cells, there has been no large-scale method to identify them, nor any effort to characterize them as a group. Here, we propose the first method for the identification of 'extreme mu...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms8412
更新日期:2015-06-09 00:00:00
abstract::Adolescence is a developmental period in which the mesolimbic dopaminergic "reward" circuitry of the brain, including the nucleus accumbens (NAc), undergoes significant plasticity. Dopamine D1 receptors (D1rs) in the NAc are critical for social behavior, but how these receptors are regulated during adolescence is not ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-06118-z
更新日期:2018-09-25 00:00:00
abstract::Application of force on biomolecules has been instrumental in understanding biofunctional behaviour from single molecules to complex collections of cells. Current approaches, for example, those based on atomic force microscopy or magnetic or optical tweezers, are powerful but limited in their applicability as integrat...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms6284
更新日期:2014-10-21 00:00:00