Maturation of the HIV-1 core by a non-diffusional phase transition.

abstract：:Electric gating can strongly modulate a wide variety of physical properties in semiconductors and insulators, such as significant changes of conductivity in silicon, appearance of superconductivity in SrTiO3, the paramagnet-ferromagnet transition in (In,Mn)As, and so on. The key to such modulation is charge accumulati...

journal_title：Nature communications

authors： Dushenko S,Hokazono M,Nakamura K,Ando Y,Shinjo T,Shiraishi M

更新日期：2018-08-07 00:00:00

abstract：:All-inorganic perovskites have a special place in halide perovskite family because of their potential for better stability. However, the representative cesium lead iodide (CsPbI3) is metastable and spontaneously converts to the non-perovskite structure at room temperature. Here, we demonstrate that what appears to be ...

journal_title：Nature communications

authors： Ke W,Spanopoulos I,Stoumpos CC,Kanatzidis MG

更新日期：2018-11-14 00:00:00

abstract：:Though the concept of Berry force was proposed thirty years ago, little is known about the practical consequences of this force as far as chemical dynamics are concerned. Here, we report that when molecular dynamics pass near a conical intersection, a massive Berry force can appear as a result of even a small amount o...

journal_title：Nature communications

authors： Wu Y,Subotnik JE

更新日期：2021-01-29 00:00:00

abstract：:TorsinA is an ER-resident AAA + ATPase, whose deletion of glutamate E303 results in the genetic neuromuscular disease primary dystonia. TorsinA is an unusual AAA + ATPase that needs an external activator. Also, it likely does not thread a peptide substrate through a narrow central channel, in contrast to its closest s...

journal_title：Nature communications

authors： Demircioglu FE,Zheng W,McQuown AJ,Maier NK,Watson N,Cheeseman IM,Denic V,Egelman EH,Schwartz TU

更新日期：2019-07-22 00:00:00

abstract：:FoxO proteins are major targets of insulin action. To better define the role of FoxO1 in mediating insulin effects in the liver, we generated liver-specific insulin receptor knockout (LIRKO) and IR/FoxO1 double knockout (LIRFKO) mice. Here we show that LIRKO mice are severely insulin resistant based on glucose, insuli...

journal_title：Nature communications

authors： O-Sullivan I,Zhang W,Wasserman DH,Liew CW,Liu J,Paik J,DePinho RA,Stolz DB,Kahn CR,Schwartz MW,Unterman TG

更新日期：2015-05-12 00:00:00

abstract：:Target-centric drug development strategies prioritize single-target potency in vitro and do not account for connectivity and multi-target effects within a signal transduction network. Here, we present a systems biology approach that combines transcriptomic and structural analyses with live-cell imaging to predict smal...

journal_title：Nature communications

authors： Pabon NA,Zhang Q,Cruz JA,Schipper DL,Camacho CJ,Lee REC

更新日期：2019-02-26 00:00:00

abstract：:The ever-increasing demand for flexible electronics calls for the development of low-voltage and high-mobility organic thin-film transistors (OTFTs) that can be integrated into emerging display and labeling technologies. Polymer dielectrics with comprehensive and balanced dielectric properties (i.e., a good balance be...

journal_title：Nature communications

authors： Ji D,Li T,Zou Y,Chu M,Zhou K,Liu J,Tian G,Zhang Z,Zhang X,Li L,Wu D,Dong H,Miao Q,Fuchs H,Hu W

更新日期：2018-06-14 00:00:00

abstract：:The turnover of messenger RNAs (mRNAs) is a key regulatory step of gene expression in eukaryotic cells. Due to the complexity of the mammalian degradation machinery, the contribution of decay factors to the directionality of mRNA decay is poorly understood. Here we characterize a molecular tool to interrogate mRNA tur...

journal_title：Nature communications

authors： Boehm V,Gerbracht JV,Marx MC,Gehring NH

更新日期：2016-12-05 00:00:00

abstract：:Positive selection in the thymus provides low-affinity T-cell receptor (TCR) engagement to support the development of potentially useful self-major histocompatibility complex class I (MHC-I)-restricted T cells. Optimal positive selection of CD8(+) T cells requires cortical thymic epithelial cells that express β5t-cont...

journal_title：Nature communications

authors： Sasaki K,Takada K,Ohte Y,Kondo H,Sorimachi H,Tanaka K,Takahama Y,Murata S

更新日期：2015-06-23 00:00:00

abstract：:Sensitive detection of protein interactions and post-translational modifications of native proteins is a challenge for research and diagnostic purposes. A method for this, which could be used in point-of-care devices and high-throughput screening, should be reliable, cost effective and robust. To achieve this, here we...

journal_title：Nature communications

authors： Koos B,Cane G,Grannas K,Löf L,Arngården L,Heldin J,Clausson CM,Klaesson A,Hirvonen MK,de Oliveira FM,Talibov VO,Pham NT,Auer M,Danielson UH,Haybaeck J,Kamali-Moghaddam M,Söderberg O

更新日期：2015-06-12 00:00:00

abstract：:Using time-domain thermoreflectance, the thermal conductivity and elastic properties of a sputter deposited LiCoO2 film, a common lithium-ion cathode material, are measured as a function of the degree of lithiation. Here we report that via in situ measurements during cycling, the thermal conductivity of a LiCoO2 catho...

journal_title：Nature communications

authors： Cho J,Losego MD,Zhang HG,Kim H,Zuo J,Petrov I,Cahill DG,Braun PV

更新日期：2014-06-03 00:00:00

abstract：:Oxygen vacancies in proximity to surfaces and heterointerfaces in oxide thin film heterostructures have major effects on properties, resulting, for example, in emergent conduction behaviour, large changes in metal-insulator transition temperatures or enhanced catalytic activity. Here we report the discovery of a means...

journal_title：Nature communications

authors： Veal BW,Kim SK,Zapol P,Iddir H,Baldo PM,Eastman JA

更新日期：2016-06-10 00:00:00

abstract：:Self-assembly of proteins and inorganic nanoparticles into terminal assemblies makes possible a large family of uniformly sized hybrid colloids. These particles can be compared in terms of utility, versatility and multifunctionality to other known types of terminal assemblies. They are simple to make and offer theoret...

journal_title：Nature communications

authors： Park JI,Nguyen TD,de Queirós Silveira G,Bahng JH,Srivastava S,Zhao G,Sun K,Zhang P,Glotzer SC,Kotov NA

更新日期：2014-05-20 00:00:00

abstract：:Alcohol oxidation reactions are widely used for the preparation of aldehydes and ketones. The electrolysis of alcohols to carbonyl compounds have been underutilized owing to low efficiency. Herein, we report an electrochemical oxidation of various alcohols in a continuous-flow reactor without external oxidants, base o...

journal_title：Nature communications

authors： Wang D,Wang P,Wang S,Chen YH,Zhang H,Lei A

更新日期：2019-06-26 00:00:00

abstract：:In 1816, the coldest summer of the past two centuries was observed over northeastern North America and western Europe. This so-called Year Without a Summer (YWAS) has been widely attributed to the 1815 eruption of Indonesia's Mt. Tambora and was concurrent with agricultural failures and famines worldwide. To understan...

journal_title：Nature communications

authors： Fasullo JT,Tomas R,Stevenson S,Otto-Bliesner B,Brady E,Wahl E

更新日期：2017-10-31 00:00:00

abstract：:In the original version of this Article, an incorrect sample size was provided for the number of relict species (443 instead of 442) and the number of relict forests (423 instead of 422). These errors have been corrected in both the PDF and HTML versions of the Article. ...

journal_title：Nature communications

authors： Tang CQ,Matsui T,Ohashi H,Dong YF,Momohara A,Herrando-Moraira S,Qian S,Yang Y,Ohsawa M,Luu HT,Grote PJ,Krestov PV,LePage B,Werger M,Robertson K,Hobohm C,Wang CY,Peng MC,Chen X,Wang HC,Su WH,Zhou R,Li S,He LY

更新日期：2018-12-04 00:00:00

abstract：:Oscillatory synchrony among neurons occurs in many species and brain areas, and has been proposed to help neural circuits process information. One hypothesis states that oscillatory input creates cyclic integration windows: specific times in each oscillatory cycle when postsynaptic neurons become especially responsive...

journal_title：Nature communications

authors： Gupta N,Singh SS,Stopfer M

更新日期：2016-12-15 00:00:00

abstract：:Emerging evidence suggests that caveolin-1 (Cav1) is associated with pulmonary arterial hypertension. MURC (also called Cavin-4) is a member of the cavin family, which regulates caveolar formation and functions together with caveolins. Here, we show that hypoxia increased Murc mRNA expression in the mouse lung, and th...

journal_title：Nature communications

authors： Nakanishi N,Ogata T,Naito D,Miyagawa K,Taniguchi T,Hamaoka T,Maruyama N,Kasahara T,Nishi M,Matoba S,Ueyama T

更新日期：2016-08-22 00:00:00

abstract：:Diatomic nitrogen is an archetypal molecular system known for its exceptional stability and complex behavior at high pressures and temperatures, including rich solid polymorphism, formation of energetic states, and an insulator-to-metal transformation coupled to a change in chemical bonding. However, the thermobaric c...

journal_title：Nature communications

authors： Jiang S,Holtgrewe N,Lobanov SS,Su F,Mahmood MF,McWilliams RS,Goncharov AF

更新日期：2018-07-06 00:00:00

abstract：:Silk and silk fibroin, the biomaterial from nature, nowadays are being widely utilized in many cutting-edge micro/nanodevices/systems via advanced micro/nanofabrication techniques. Herein, for the first time to our knowledge, we report aqueous multiphoton lithography of diversiform-regenerated-silk-fibroin-centric ink...

journal_title：Nature communications

authors： Sun YL,Li Q,Sun SM,Huang JC,Zheng BY,Chen QD,Shao ZZ,Sun HB

更新日期：2015-10-16 00:00:00

abstract：:Clonal expansions occur in the persistent HIV reservoir as shown by the duplication of proviral integration sites. However, the source of the proliferation of HIV-infected cells remains unclear. Here, we analyze the TCR repertoire of single HIV-infected cells harboring translation-competent proviruses in longitudinal ...

journal_title：Nature communications

authors： Gantner P,Pagliuzza A,Pardons M,Ramgopal M,Routy JP,Fromentin R,Chomont N

更新日期：2020-08-14 00:00:00

abstract：:In eukaryotic cells, organellar proteome biogenesis is pivotal for cellular function. Chloroplasts contain a complex proteome, the biogenesis of which includes post-translational import of nuclear-encoded proteins. However, the mechanisms determining when and how nascent chloroplast-targeted proteins are sorted in the...

journal_title：Nature communications

authors： Kim DH,Lee JE,Xu ZY,Geem KR,Kwon Y,Park JW,Hwang I

更新日期：2015-04-16 00:00:00

abstract：:The exploration of chemical space for new reactivity, reactions and molecules is limited by the need for separate work-up-separation steps searching for molecules rather than reactivity. Herein we present a system that can autonomously evaluate chemical reactivity within a network of 64 possible reaction combinations ...

journal_title：Nature communications

authors： Dragone V,Sans V,Henson AB,Granda JM,Cronin L

更新日期：2017-06-09 00:00:00

abstract：:Current knowledge on chromosomal mosaicism in human cell cultures is mostly based on cytogenetic banding methods. The recent development of high-resolution full-genome analysis methods applicable to single cells is providing new insights into genetic and cellular diversity. Here we study the genetic content of 92 indi...

journal_title：Nature communications

authors： Jacobs K,Mertzanidou A,Geens M,Nguyen HT,Staessen C,Spits C

更新日期：2014-06-27 00:00:00

abstract：:Although many animals have evolved intrinsic transparency for the purpose of concealment, the development of dynamic, that is, controllable and reversible, transparency for living human cells and tissues has remained elusive to date. Here, by drawing inspiration from the structures and functionalities of adaptive ceph...

journal_title：Nature communications

authors： Chatterjee A,Cerna Sanchez JA,Yamauchi T,Taupin V,Couvrette J,Gorodetsky AA

更新日期：2020-06-02 00:00:00

abstract：:Transcription initiation involves the coordinated activities of large multimeric complexes, but little is known about their biogenesis. Here we report several principles underlying the assembly and topological organization of the highly conserved SAGA and NuA4 co-activator complexes, which share the Tra1 subunit. We s...

journal_title：Nature communications

authors： Elías-Villalobos A,Toullec D,Faux C,Séveno M,Helmlinger D

更新日期：2019-11-20 00:00:00

abstract：:A key mechanism of bacterial resistance to macrolide antibiotics is the dimethylation of a nucleotide in the large ribosomal subunit by erythromycin resistance methyltransferases. The majority of erm genes are expressed only when the antibiotic is present and the erythromycin resistance methyltransferase activity is c...

journal_title：Nature communications

authors： Gupta P,Sothiselvam S,Vázquez-Laslop N,Mankin AS

更新日期：2013-01-01 00:00:00

abstract：:Understanding and predicting radiation damage evolution in complex materials is crucial for developing next-generation nuclear energy sources. Here, using a combination of ion beam irradiation, transmission electron microscopy and X-ray diffraction, we show that, contrary to the behaviour observed in pyrochlores, the ...

journal_title：Nature communications

authors： Uberuaga BP,Tang M,Jiang C,Valdez JA,Smith R,Wang Y,Sickafus KE

更新日期：2015-10-29 00:00:00

abstract：:Long duration gamma-ray bursts (GRBs), the brightest events since the Big Bang itself, are believed to originate in an ultra-relativistic jet breaking out from a massive stellar envelope. Despite decades of study, there is still no consensus on their emission mechanism. One unresolved question is the origin of the tig...

journal_title：Nature communications

authors： Ito H,Matsumoto J,Nagataki S,Warren DC,Barkov MV,Yonetoku D

更新日期：2019-04-03 00:00:00

abstract：:We introduce a microfluidic platform that enables off-chip single-cell RNA-seq after multi-generational lineage tracking under controlled culture conditions. We use this platform to generate whole-transcriptome profiles of primary, activated murine CD8+ T-cell and lymphocytic leukemia cell line lineages. Here we repor...

journal_title：Nature communications

authors： Kimmerling RJ,Lee Szeto G,Li JW,Genshaft AS,Kazer SW,Payer KR,de Riba Borrajo J,Blainey PC,Irvine DJ,Shalek AK,Manalis SR

更新日期：2016-01-06 00:00:00