Abstract:
:In the original version of this Article, an incorrect sample size was provided for the number of relict species (443 instead of 442) and the number of relict forests (423 instead of 422). These errors have been corrected in both the PDF and HTML versions of the Article.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Tang CQ,Matsui T,Ohashi H,Dong YF,Momohara A,Herrando-Moraira S,Qian S,Yang Y,Ohsawa M,Luu HT,Grote PJ,Krestov PV,LePage B,Werger M,Robertson K,Hobohm C,Wang CY,Peng MC,Chen X,Wang HC,Su WH,Zhou R,Li S,He LYdoi
10.1038/s41467-018-07727-4subject
Has Abstractpub_date
2018-12-04 00:00:00pages
5241issue
1issn
2041-1723pii
10.1038/s41467-018-07727-4journal_volume
9pub_type
杂志文章,已发布勘误abstract::Regulation of protein N-glycosylation is essential in human cells. However, large-scale, accurate, and site-specific quantification of glycosylation is still technically challenging. We here introduce SugarQuant, an integrated mass spectrometry-based pipeline comprising protein aggregation capture (PAC)-based sample p...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19052-w
更新日期:2020-10-19 00:00:00
abstract::Electrochemical water splitting requires efficient water oxidation catalysts to accelerate the sluggish kinetics of water oxidation reaction. Here, we report a promisingly dendritic core-shell nickel-iron-copper metal/metal oxide electrode, prepared via dealloying with an electrodeposited nickel-iron-copper alloy as a...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-02429-9
更新日期:2018-01-26 00:00:00
abstract::Membrane transporters actively translocate their substrate by undergoing large-scale structural transitions between inward- (IF) and outward-facing (OF) states ('alternating-access' mechanism). Despite extensive structural studies, atomic-level mechanistic details of such structural transitions, and as importantly, th...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms9393
更新日期:2015-09-29 00:00:00
abstract::Understanding and predicting radiation damage evolution in complex materials is crucial for developing next-generation nuclear energy sources. Here, using a combination of ion beam irradiation, transmission electron microscopy and X-ray diffraction, we show that, contrary to the behaviour observed in pyrochlores, the ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms9750
更新日期:2015-10-29 00:00:00
abstract::Microbial fatty acid-derived fuels have emerged as promising alternatives to petroleum-based transportation fuels. Here we report a modular engineering approach that systematically removed metabolic pathway bottlenecks and led to significant titre improvements in a multi-gene fatty acid metabolic pathway. On the basis...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms2425
更新日期:2013-01-01 00:00:00
abstract::Myxofibrosarcoma (MFS) is a common adult soft tissue sarcoma characterized by an infiltrative growth pattern and a high local recurrence rate. Here we report the genetic and epigenetic landscape of MFS based on the results of whole-exome sequencing (N = 41), RNA sequencing (N = 29), and methylation analysis (N = 41), ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03891-9
更新日期:2018-07-17 00:00:00
abstract::Neural computation relies on the integration of synaptic inputs across a neuron's dendritic arbour. However, it is far from understood how different cell types tune this process to establish cell-type specific computations. Here, using two-photon imaging of dendritic Ca2+ signals, electrical recordings of somatic volt...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-15867-9
更新日期:2020-04-30 00:00:00
abstract::The rise of antibiotic-resistant bacteria has led to an urgent need for rapid detection of drug resistance in clinical samples, and improvements in global surveillance. Here we show how de Bruijn graph representation of bacterial diversity can be used to identify species and resistance profiles of clinical isolates. W...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10063
更新日期:2015-12-21 00:00:00
abstract::The activation of a neuronal ensemble in the central nucleus of the amygdala (CeA) during alcohol withdrawal has been hypothesized to induce high levels of alcohol drinking in dependent rats. In the present study we describe that the CeA neuronal ensemble that is activated by withdrawal from chronic alcohol exposure c...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09183-0
更新日期:2019-03-18 00:00:00
abstract::Natural killer (NK) cells limit viral replication by direct recognition of infected cells, antibody-dependent cellular cytotoxicity (ADCC), and releasing cytokines. Although growing evidence supports NK cell antiviral immunity in HIV-1 infection, further knowledge of their response is necessary. Here we show that NK c...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03618-w
更新日期:2018-03-23 00:00:00
abstract::Intentional doping is the core of semiconductor technologies to tune electrical and optical properties of semiconductors for electronic devices, however, it has shown to be a grand challenge for halide perovskites. Here, we show that some metal ions, such as silver, strontium, cerium ions, which exist in the precursor...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-20110-6
更新日期:2021-01-04 00:00:00
abstract::Repeat-associated non-AUG (RAN) translation allows for unconventional initiation at disease-causing repeat expansions. As RAN translation contributes to pathogenesis in multiple neurodegenerative disorders, determining its mechanistic underpinnings may inform therapeutic development. Here we analyze RAN translation at...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-02200-0
更新日期:2017-12-08 00:00:00
abstract::Endolysosomal organelles play a key role in trafficking, breakdown and receptor-mediated recycling of different macromolecules such as low-density lipoprotein (LDL)-cholesterol, epithelial growth factor (EGF) or transferrin. Here we examine the role of two-pore channel (TPC) 2, an endolysosomal cation channel, in thes...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms5699
更新日期:2014-08-21 00:00:00
abstract::In June 2015, Cassini high-resolution images of Saturn's limb southwards of the planet's hexagonal wave revealed a system of at least six stacked haze layers above the upper cloud deck. Here, we characterize those haze layers and discuss their nature. Vertical thickness of layers ranged from 7 to 18 km, and they exten...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16110-1
更新日期:2020-05-08 00:00:00
abstract::Strain engineering is widely used in material science to tune the (opto-)electronic properties of materials and enhance the performance of devices. Two-dimensional atomic crystals are a versatile playground to study the influence of strain, as they can sustain very large deformations without breaking. Various optical ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-02830-y
更新日期:2018-02-06 00:00:00
abstract::Rotational invariance strongly constrains the viscosity tensor of classical fluids. When this symmetry is broken in anisotropic materials a wide array of novel phenomena become possible. We explore electron fluid behaviors arising from the most general viscosity tensors in two and three dimensions, constrained only th...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-18553-y
更新日期:2020-09-18 00:00:00
abstract::Amazon forests have experienced frequent and severe droughts in the past two decades. However, little is known about the large-scale legacy of droughts on carbon stocks and dynamics of forests. Using systematic sampling of forest structure measured by LiDAR waveforms from 2003 to 2008, here we show a significant loss ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-05668-6
更新日期:2018-08-09 00:00:00
abstract::Most seafloor hydrothermal circulation occurs far from the magmatic influence of mid-ocean ridges, driving large flows of water, heat and solutes through volcanic rock outcrops on ridge flanks. Here we create three-dimensional simulations of ridge-flank hydrothermal circulation, flowing between and through seamounts, ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms8567
更新日期:2015-06-26 00:00:00
abstract::Pulmonary disease increases the risk of developing abdominal aortic aneurysms (AAA). However, the mechanism underlying the pathological dialogue between the lungs and aorta is undefined. Here, we find that inflicting acute lung injury (ALI) to mice doubles their incidence of AAA and accelerates macrophage-driven prote...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-18088-2
更新日期:2020-08-27 00:00:00
abstract::Graphite dual-ion batteries represent a potential battery concept for large-scale stationary storage of electricity, especially when constructed free of lithium and other chemical elements with limited natural reserves. Owing to their non-rocking-chair operation mechanism, however, the practical deployment of graphite...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-06923-6
更新日期:2018-10-26 00:00:00
abstract::The quiescent centre (QC) in the Arabidopsis root apical meristem is essential for stem cell organization. Here we show that the loss of REPRESSOR OF WUSCHEL1 (ROW1), a PHD domain-containing protein, leads to QC failure, defects in cell differentiation and ectopic expression of WUSCHEL-RELATED HOMEOBOX 5 (WOX5) in cel...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms7003
更新日期:2015-01-29 00:00:00
abstract::Graphene and hexagonal boron nitride are typical conductor and insulator, respectively, while their hybrids hexagonal boron carbonitride are promising as a semiconductor. Here we demonstrate a direct chemical conversion reaction, which systematically converts the hexagonal carbon lattice of graphene to boron nitride, ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms4193
更新日期:2014-01-01 00:00:00
abstract::Identification of the optimal quantum metrological protocols in realistic many particle quantum models is in general a challenge that cannot be efficiently addressed by the state-of-the-art numerical and analytical methods. Here we provide a comprehensive framework exploiting matrix product operators (MPO) type tensor...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13735-9
更新日期:2020-01-14 00:00:00
abstract::Bacterial Type III Secretion Systems deliver effectors into host cells to manipulate cellular processes to the advantage of the pathogen. Many host targets of these effectors are found on membranes. Therefore, to identify their targets, effectors often use specialized membrane-localization domains to localize to appro...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3973
更新日期:2013-01-01 00:00:00
abstract::Quantum computers promise to solve certain problems more efficiently than their digital counterparts. A major challenge towards practically useful quantum computing is characterizing and reducing the various errors that accumulate during an algorithm running on large-scale processors. Current characterization techniqu...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13068-7
更新日期:2019-11-25 00:00:00
abstract::The manipulation of magnetic ordering with applied electric fields is of pressing interest for new magnetoelectric devices and information storage applications. Recently, such magnetoelectric control was realized in multiferroics. However, their magnetoelectric switching is often accompanied by significant hysteresis,...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms4201
更新日期:2014-01-01 00:00:00
abstract::Bacteria release membrane vesicles (MVs) that play important roles in various biological processes. However, the mechanisms of MV formation in Gram-positive bacteria are unclear, as these cells possess a single cytoplasmic membrane that is surrounded by a thick cell wall. Here we use live cell imaging and electron cry...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-00492-w
更新日期:2017-09-07 00:00:00
abstract::Notwithstanding the central biological role of the (6-4) photoadduct in the induction of skin cancer by sunlight, crucial mechanistic details about its formation have evaded characterization despite efforts spanning more than half a century. 4-Thiothymidine (4tT) has been widely used as an important model system to st...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-17333-y
更新日期:2020-07-17 00:00:00
abstract::Profound global loss of DNA methylation is a hallmark of many cancers. One potential consequence of this is the reactivation of transposable elements (TEs) which could stimulate the immune system via cell-intrinsic antiviral responses. Here, we develop REdiscoverTE, a computational method for quantifying genome-wide T...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13035-2
更新日期:2019-11-19 00:00:00
abstract::Radiotherapy is not currently informed by the genetic composition of an individual patient's tumour. To identify genetic features regulating survival after DNA damage, here we conduct large-scale profiling of cellular survival after exposure to radiation in a diverse collection of 533 genetically annotated human tumou...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms11428
更新日期:2016-04-25 00:00:00