ROW1 maintains quiescent centre identity by confining WOX5 expression to specific cells.

abstract：:In patients with damage to the primary visual cortex (V1), residual vision can guide goal-directed movements to targets in the blind field without awareness. This phenomenon has been termed blindsight, and its neural mechanisms are controversial. There should be visual pathways to the higher visual cortices bypassing ...

journal_title：Nature communications

authors： Kinoshita M,Kato R,Isa K,Kobayashi K,Kobayashi K,Onoe H,Isa T

更新日期：2019-01-11 00:00:00

abstract：:Much of the global annual mean temperature change over Quaternary glacial cycles can be attributed to slow ice sheet and greenhouse gas feedbacks, but analysis of the short-term response to orbital forcings has the potential to reveal key relationships in the climate system. In particular, obliquity and precession bot...

journal_title：Nature communications

authors： Erb MP,Jackson CS,Broccoli AJ,Lea DW,Valdes PJ,Crucifix M,DiNezio PN

更新日期：2018-04-10 00:00:00

abstract：:Macrophages regulate host responses to implants through their dynamic adhesion, release, and activation. Herein, we employ bisphosphonate (BP)-coated gold nanoparticle template (BNP) to direct the swift and convertible formation of Mg2+-functional Mg2+-BP nanoparticle (NP) on the BP-AuNP surface via reversible Mg2+-BP...

journal_title：Nature communications

authors： Kang H,Yang B,Zhang K,Pan Q,Yuan W,Li G,Bian L

更新日期：2019-04-12 00:00:00

abstract：:Enantioenriched 1,4-dienes are versatile building blocks in asymmetric synthesis, therefore their efficient synthesis directly from chemical feedstock is highly sought after. Here, we show an enantioselective cross-hydroalkenylation of cyclic 1,3-diene and hetero-substituted terminal olefin by using a chiral [NHC-Ni(a...

journal_title：Nature communications

authors： Chen Y,Dang L,Ho CY

更新日期：2020-05-08 00:00:00

abstract：:EGFR is required for animal development, and dysregulation of EGFR is critically implicated in malignant transformation. However, the molecular mechanism underlying the regulation of EGFR expression remains poorly explored. Here we report that the zinc-finger protein ZNF516 is a transcription repressor. ZNF516 is phys...

journal_title：Nature communications

authors： Li L,Liu X,He L,Yang J,Pei F,Li W,Liu S,Chen Z,Xie G,Xu B,Ting X,Zhang Z,Jin T,Liu X,Zhang W,Yuan S,Yang Z,Wu C,Zhang Y,Yang X,Yi X,Liang J,Shang Y,Sun L

更新日期：2017-09-25 00:00:00

abstract：:Osteoporosis is a devastating disease with an essential genetic component. GWAS have discovered genetic signals robustly associated with bone mineral density (BMD), but not the precise localization of effector genes. Here, we carry out physical and direct variant to gene mapping in human mesenchymal progenitor cell-de...

journal_title：Nature communications

authors： Chesi A,Wagley Y,Johnson ME,Manduchi E,Su C,Lu S,Leonard ME,Hodge KM,Pippin JA,Hankenson KD,Wells AD,Grant SFA

更新日期：2019-03-19 00:00:00

abstract：:In contrast to processive molecular motors, skeletal myosins form a large motor ensemble for contraction of muscles against high loads. Despite numerous information on the molecular properties of skeletal myosin, its ensemble effects on collective force generation have not been rigorously clarified. Here we show 4 nm ...

journal_title：Nature communications

authors： Kaya M,Tani Y,Washio T,Hisada T,Higuchi H

更新日期：2017-07-06 00:00:00

abstract：:High-performance piezoelectrics are lead-based solid solutions that exhibit a so-called morphotropic phase boundary, which separates two competing phases as a function of chemical composition; as a consequence, an intermediate low-symmetry phase with a strong piezoelectric effect arises. In search for environmentally ...

journal_title：Nature communications

authors： Lummen TT,Gu Y,Wang J,Lei S,Xue F,Kumar A,Barnes AT,Barnes E,Denev S,Belianinov A,Holt M,Morozovska AN,Kalinin SV,Chen LQ,Gopalan V

更新日期：2014-01-01 00:00:00

abstract：:Different symmetry breaking ways determine various magnetization switching modes driven by spin-orbit torques (SOT). For instance, an applied or effective field parallel to applied current is indispensable to switch magnetization with perpendicular anisotropy by SOT. Besides of this mode, here we experimentally demons...

journal_title：Nature communications

authors： Kong WJ,Wan CH,Wang X,Tao BS,Huang L,Fang C,Guo CY,Guang Y,Irfan M,Han XF

更新日期：2019-01-16 00:00:00

abstract：:Several of the steps in protein synthesis on the ribosome utilize hydrolysis of guanosine triphosphate (GTP) as the driving force. This reaction is catalyzed by translation factors that become activated upon binding to the ribosome. The recently determined crystal structure of an elongation factor-Tu ternary complex b...

journal_title：Nature communications

authors： Wallin G,Kamerlin SC,Aqvist J

更新日期：2013-01-01 00:00:00

abstract：:Perovskite solar cells have received worldwide interests due to swiftly improved efficiency but the poor stability of the perovskite component hampers the device fabrication under normal condition. Herein, we develop a reliable nonstoichiometric acid-base reaction route to stable perovskite films by intermediate chemi...

journal_title：Nature communications

authors： Long M,Zhang T,Chai Y,Ng CF,Mak TC,Xu J,Yan K

更新日期：2016-11-15 00:00:00

abstract：:The possibility of measuring binding of small-molecule drugs to desired targets in live cells could provide a better understanding of drug action. However, current approaches mostly yield static data, require lysis or rely on indirect assays and thus often provide an incomplete understanding of drug action. Here, we p...

journal_title：Nature communications

authors： Dubach JM,Vinegoni C,Mazitschek R,Fumene Feruglio P,Cameron LA,Weissleder R

更新日期：2014-05-28 00:00:00

abstract：:Despite tremendous importance in catalysis, the design of oxide-metal interface has been hampered by the limited understanding of the nature of interfacial sites and the oxide-metal interaction (OMI). Through construction of well-defined Cu2O/Pt, Cu2O/Ag and Cu2O/Au interfaces, we find that Cu2O nanostructures (NSs) o...

journal_title：Nature communications

authors： Huang W,Liu Q,Zhou Z,Li Y,Ling Y,Wang Y,Tu Y,Wang B,Zhou X,Deng D,Yang B,Yang Y,Liu Z,Bao X,Yang F

更新日期：2020-05-08 00:00:00

abstract：:Tomatoes come in a multitude of shapes and flavors despite a narrow genetic pool. Here, we leverage whole-genome resequencing data available for 602 cultivated and wild accessions to determine the contribution of transposable elements (TEs) to tomato diversity. We identify 6,906 TE insertions polymorphisms (TIPs), whi...

journal_title：Nature communications

authors： Domínguez M,Dugas E,Benchouaia M,Leduque B,Jiménez-Gómez JM,Colot V,Quadrana L

更新日期：2020-08-13 00:00:00

abstract：:Compartmentalization of the gut microbiota is thought to be important to system function, but the extent of spatial organization in the gut ecosystem remains poorly understood. Here, we profile the murine colonic microbiota along longitudinal and lateral axes using laser capture microdissection. We found fine-scale sp...

journal_title：Nature communications

authors： Riva A,Kuzyk O,Forsberg E,Siuzdak G,Pfann C,Herbold C,Daims H,Loy A,Warth B,Berry D

更新日期：2019-09-25 00:00:00

abstract：:An elusive goal in the field of driven quantum matter is the induction of long-range order. Here, we propose a mechanism based on light-induced evaporative cooling of holes in a correlated fermionic system. Since the entropy of a filled narrow band grows rapidly with hole doping, the isentropic transfer of holes from ...

journal_title：Nature communications

authors： Werner P,Eckstein M,Müller M,Refael G

更新日期：2019-12-05 00:00:00

abstract：:Stackable select devices such as the oxide p-n junction diode and the Schottky diode (one-way switch) have been proposed for non-volatile unipolar resistive switching devices; however, bidirectional select devices (or two-way switch) need to be developed for bipolar resistive switching devices. Here we report on a ful...

journal_title：Nature communications

authors： Lee MJ,Lee D,Cho SH,Hur JH,Lee SM,Seo DH,Kim DS,Yang MS,Lee S,Hwang E,Uddin MR,Kim H,Chung UI,Park Y,Yoo IK

更新日期：2013-01-01 00:00:00

abstract：:Two-dimensional hybrid organic-inorganic perovskites with strongly bound excitons and tunable structures are desirable for optoelectronic applications. Exciton transport and annihilation are two key processes in determining device efficiencies; however, a thorough understanding of these processes is hindered by that a...

journal_title：Nature communications

authors： Deng S,Shi E,Yuan L,Jin L,Dou L,Huang L

更新日期：2020-01-31 00:00:00

abstract：:Diversity-oriented synthesis (DOS) can provide a collection of diverse and complex drug-like small molecules, which is critical in the development of new chemical probes for biological research of undruggable targets. However, the design and synthesis of small-molecule libraries with improved biological relevance as w...

journal_title：Nature communications

authors： Kim J,Jung J,Koo J,Cho W,Lee WS,Kim C,Park W,Park SB

更新日期：2016-10-24 00:00:00

abstract：:Gate operations in a quantum information processor are generally realized by tailoring specific periods of free and driven evolution of a quantum system. Unwanted environmental noise, which may in principle be distinct during these two periods, acts to decohere the system and increase the gate error rate. Although the...

journal_title：Nature communications

authors： Yan F,Gustavsson S,Bylander J,Jin X,Yoshihara F,Cory DG,Nakamura Y,Orlando TP,Oliver WD

更新日期：2013-01-01 00:00:00

abstract：:Some bacteria can feed on fungi, a phenomenon known as mycophagy. Here we show that a prophage tail-like protein (Bg_9562) is essential for mycophagy in Burkholderia gladioli strain NGJ1. The purified protein causes hyphal disintegration and inhibits growth of several fungal species. Disruption of the Bg_9562 gene abo...

journal_title：Nature communications

authors： Swain DM,Yadav SK,Tyagi I,Kumar R,Kumar R,Ghosh S,Das J,Jha G

更新日期：2017-09-01 00:00:00

abstract：:Overcoming the restricted axonal regenerative ability that limits functional repair following a central nervous system injury remains a challenge. Here we report a regenerative paradigm that we call enriched conditioning, which combines environmental enrichment (EE) followed by a conditioning sciatic nerve axotomy tha...

journal_title：Nature communications

authors： De Virgiliis F,Hutson TH,Palmisano I,Amachree S,Miao J,Zhou L,Todorova R,Thompson R,Danzi MC,Lemmon VP,Bixby JL,Wittig I,Shah AM,Di Giovanni S

更新日期：2020-12-21 00:00:00

abstract：:Metallic nanostructures exhibit a multitude of optical resonances associated with localized surface plasmon excitations. Recent observations of plasmonic phenomena at the sub-nanometre to atomic scale have stimulated the development of various sophisticated theoretical approaches for their description. Here instead we...

journal_title：Nature communications

authors： Mortensen NA,Raza S,Wubs M,Søndergaard T,Bozhevolnyi SI

更新日期：2014-05-02 00:00:00

abstract：:Despite the global impact of macrophage activation in vascular disease, the underlying mechanisms remain obscure. Here we show, with global proteomic analysis of macrophage cell lines treated with either IFNγ or IL-4, that PARP9 and PARP14 regulate macrophage activation. In primary macrophages, PARP9 and PARP14 have o...

journal_title：Nature communications

authors： Iwata H,Goettsch C,Sharma A,Ricchiuto P,Goh WW,Halu A,Yamada I,Yoshida H,Hara T,Wei M,Inoue N,Fukuda D,Mojcher A,Mattson PC,Barabási AL,Boothby M,Aikawa E,Singh SA,Aikawa M

更新日期：2016-10-31 00:00:00

abstract：:Sphingomyelin phosphodiesterase acid-like 3b (SMPDL3b) is a lipid raft enzyme that regulates plasma membrane (PM) fluidity. Here we report that SMPDL3b excess, as observed in podocytes in diabetic kidney disease (DKD), impairs insulin receptor isoform B-dependent pro-survival insulin signaling by interfering with insu...

journal_title：Nature communications

authors： Mitrofanova A,Mallela SK,Ducasa GM,Yoo TH,Rosenfeld-Gur E,Zelnik ID,Molina J,Varona Santos J,Ge M,Sloan A,Kim JJ,Pedigo C,Bryn J,Volosenco I,Faul C,Zeidan YH,Garcia Hernandez C,Mendez AJ,Leibiger I,Burke GW,Futerm

更新日期：2019-06-19 00:00:00

abstract：:A key question of theoretical ecology is which properties of ecosystems favour their stability and help maintaining biodiversity. This question recently reconsidered mutualistic systems, generating intense controversy about the role of mutualistic interactions and their network architecture. Here we show analytically ...

journal_title：Nature communications

authors： Pascual-García A,Bastolla U

更新日期：2017-02-24 00:00:00

abstract：:Skill learning is instantiated by changes to functional connectivity within premotor circuits, but whether the specificity of learning depends on structured changes to inhibitory circuitry remains unclear. We used slice electrophysiology to measure connectivity changes associated with song learning in the avian analog...

journal_title：Nature communications

authors： Miller MN,Cheung CYJ,Brainard MS

更新日期：2017-12-13 00:00:00

abstract：:Epilepsy-the propensity toward recurrent, unprovoked seizures-is a devastating disease affecting 65 million people worldwide. Understanding and treating this disease remains a challenge, as seizures manifest through mechanisms and features that span spatial and temporal scales. Here we address this challenge through t...

journal_title：Nature communications

authors： Martinet LE,Fiddyment G,Madsen JR,Eskandar EN,Truccolo W,Eden UT,Cash SS,Kramer MA

更新日期：2017-04-04 00:00:00

abstract：:Collisions between the DNA replication machinery and co-transcriptional R-loops can impede DNA synthesis and are a major source of genomic instability in cancer cells. How cancer cells deal with R-loops to proliferate is poorly understood. Here we show that the ATP-dependent chromatin remodelling INO80 complex promote...

journal_title：Nature communications

authors： Prendergast L,McClurg UL,Hristova R,Berlinguer-Palmini R,Greener S,Veitch K,Hernandez I,Pasero P,Rico D,Higgins JMG,Gospodinov A,Papamichos-Chronakis M

更新日期：2020-09-10 00:00:00

abstract：:Most chemical vapor deposition methods for transition metal dichalcogenides use an extremely small amount of precursor to render large single-crystal flakes, which usually causes low coverage of the materials on the substrate. In this study, a self-capping vapor-liquid-solid reaction is proposed to fabricate large-gra...

journal_title：Nature communications

authors： Chang MC,Ho PH,Tseng MF,Lin FY,Hou CH,Lin IK,Wang H,Huang PP,Chiang CH,Yang YC,Wang IT,Du HY,Wen CY,Shyue JJ,Chen CW,Chen KH,Chiu PW,Chen LC

更新日期：2020-07-23 00:00:00