Dynamic kirigami structures for integrated solar tracking.

abstract：:Bacterial Type III Secretion Systems deliver effectors into host cells to manipulate cellular processes to the advantage of the pathogen. Many host targets of these effectors are found on membranes. Therefore, to identify their targets, effectors often use specialized membrane-localization domains to localize to appro...

journal_title：Nature communications

authors： Salomon D,Guo Y,Kinch LN,Grishin NV,Gardner KH,Orth K

更新日期：2013-01-01 00:00:00

abstract：:Cell biologists generally consider that microtubules and actin play complementary roles in long- and short-distance transport in animal cells. On the contrary, using melanosomes of melanocytes as a model, we recently discovered that the motor protein myosin-Va works with dynamic actin tracks to drive long-range organe...

journal_title：Nature communications

authors： Alzahofi N,Welz T,Robinson CL,Page EL,Briggs DA,Stainthorp AK,Reekes J,Elbe DA,Straub F,Kallemeijn WW,Tate EW,Goff PS,Sviderskaya EV,Cantero M,Montoliu L,Nedelec F,Miles AK,Bailly M,Kerkhoff E,Hume AN

更新日期：2020-07-13 00:00:00

abstract：:Long-range chromatin interactions are important for transcriptional regulation of genes, many of which are related to complex agronomics traits. However, the pattern of three-dimensional chromatin interactions remains unclear in plants. Here we report the generation of chromatin interaction analysis by paired-end tag ...

journal_title：Nature communications

authors： Li E,Liu H,Huang L,Zhang X,Dong X,Song W,Zhao H,Lai J

更新日期：2019-06-14 00:00:00

abstract：:Adult neural stem cells reside in a specialized niche in the subventricular zone (SVZ). Throughout life they give rise to adult-born neurons in the olfactory bulb (OB), thus contributing to neural plasticity and pattern discrimination. Here, we show that the neurovascular protein EGFL7 is secreted by endothelial cells...

journal_title：Nature communications

authors： Bicker F,Vasic V,Horta G,Ortega F,Nolte H,Kavyanifar A,Keller S,Stankovic ND,Harter PN,Benedito R,Lutz B,Bäuerle T,Hartwig J,Baumgart J,Krüger M,Radyushkin K,Alberi L,Berninger B,Schmidt MHH

更新日期：2017-06-28 00:00:00

abstract：:Mutations in fused in sarcoma (FUS) lead to amyotrophic lateral sclerosis (ALS) with varying ages of onset, progression and severity. This suggests that unknown genetic factors contribute to disease pathogenesis. Here we show the identification of muscleblind as a novel modifier of FUS-mediated neurodegeneration in vi...

journal_title：Nature communications

authors： Casci I,Krishnamurthy K,Kour S,Tripathy V,Ramesh N,Anderson EN,Marrone L,Grant RA,Oliver S,Gochenaur L,Patel K,Sterneckert J,Gleixner AM,Donnelly CJ,Ruepp MD,Sini AM,Zuccaro E,Pennuto M,Pasinelli P,Pandey UB

更新日期：2019-12-06 00:00:00

abstract：:Recent developments in stem cell biology have enabled the study of cell fate decisions in early human development that are impossible to study in vivo. However, understanding how development varies across individuals and, in particular, the influence of common genetic variants during this process has not been characte...

journal_title：Nature communications

authors： Cuomo ASE,Seaton DD,McCarthy DJ,Martinez I,Bonder MJ,Garcia-Bernardo J,Amatya S,Madrigal P,Isaacson A,Buettner F,Knights A,Natarajan KN,HipSci Consortium.,Vallier L,Marioni JC,Chhatriwala M,Stegle O

更新日期：2020-02-10 00:00:00

abstract：:Aberrant metabolism of cancer cells is well appreciated, but the identification of cancer subsets with specific metabolic vulnerabilities remains challenging. We conducted a chemical biology screen and identified a subset of neuroendocrine tumors displaying a striking pattern of sensitivity to inhibition of the choles...

journal_title：Nature communications

authors： Mahoney CE,Pirman D,Chubukov V,Sleger T,Hayes S,Fan ZP,Allen EL,Chen Y,Huang L,Liu M,Zhang Y,McDonald G,Narayanaswamy R,Choe S,Chen Y,Gross S,Cianchetta G,Padyana AK,Murray S,Liu W,Marks KM,Murtie J,Dorsch M,

更新日期：2019-01-09 00:00:00

abstract：:Angiogenesis is a dynamic process relying on endothelial cell rearrangements within vascular tubes, yet the underlying mechanisms and functional relevance are poorly understood. Here we show that PI3Kα regulates endothelial cell rearrangements using a combination of a PI3Kα-selective inhibitor and endothelial-specific...

journal_title：Nature communications

authors： Angulo-Urarte A,Casado P,Castillo SD,Kobialka P,Kotini MP,Figueiredo AM,Castel P,Rajeeve V,Milà-Guasch M,Millan J,Wiesner C,Serra H,Muixi L,Casanovas O,Viñals F,Affolter M,Gerhardt H,Huveneers S,Belting HG,Cutillas

更新日期：2018-11-16 00:00:00

abstract：:DNA strands of well-defined sequence are valuable in synthetic biology and nanostructure assembly. Drawing inspiration from solid-phase synthesis, here we describe a DNA assembly method that uses time, or order of addition, as a parameter to define structural complexity. DNA building blocks are sequentially added with...

journal_title：Nature communications

authors： Hamblin GD,Rahbani JF,Sleiman HF

更新日期：2015-05-05 00:00:00

abstract：:Forests impact regional hydrology and climate directly by regulating water and heat fluxes. Indirect effects through cloud formation and precipitation can be important in facilitating continental-scale moisture recycling but are poorly understood at regional scales. In particular, the impact of temperate forest on clo...

journal_title：Nature communications

authors： Teuling AJ,Taylor CM,Meirink JF,Melsen LA,Miralles DG,van Heerwaarden CC,Vautard R,Stegehuis AI,Nabuurs GJ,de Arellano JV

更新日期：2017-01-11 00:00:00

abstract：:HIV can be partially contained by host immunity and understanding the basis of this may inform vaccine design. The importance of B-cell function in long-term control is poorly understood. One method of investigating this is in vivo cellular depletion. In this study, we take advantage of a unique opportunity to investi...

journal_title：Nature communications

authors： Huang KH,Bonsall D,Katzourakis A,Thomson EC,Fidler SJ,Main J,Muir D,Weber JN,Frater AJ,Phillips RE,Pybus OG,Goulder PJ,McClure MO,Cooke GS,Klenerman P

更新日期：2010-10-19 00:00:00

abstract：:Marine reserves are viewed as flagship tools to protect exploited species and to contribute to the effective management of coastal fisheries. Yet, the extent to which marine reserves are globally interconnected and able to effectively seed areas, where fisheries are most critical for food and livelihood security is la...

journal_title：Nature communications

authors： Andrello M,Guilhaumon F,Albouy C,Parravicini V,Scholtens J,Verley P,Barange M,Sumaila UR,Manel S,Mouillot D

更新日期：2017-07-10 00:00:00

abstract：:MADS-domain transcription factors have been shown to act as key repressors or activators of the transition to flowering and as master regulators of reproductive organ identities. Despite their important roles in plant development, the origin of several MADS-box subfamilies has remained enigmatic so far. Here we demons...

journal_title：Nature communications

authors： Ruelens P,de Maagd RA,Proost S,Theißen G,Geuten K,Kaufmann K

更新日期：2013-01-01 00:00:00

abstract：:Visualization of ion transport in electrolytes provides fundamental understandings of electrolyte dynamics and electrolyte-electrode interactions. However, this is challenging because existing techniques are hard to capture low ionic concentrations and fast electrolyte dynamics. Here we show that stimulated Raman scat...

journal_title：Nature communications

authors： Cheng Q,Wei L,Liu Z,Ni N,Sang Z,Zhu B,Xu W,Chen M,Miao Y,Chen LQ,Min W,Yang Y

更新日期：2018-07-30 00:00:00

abstract：:One of the key applications of quantum information is simulating nature. Fermions are ubiquitous in nature, appearing in condensed matter systems, chemistry and high energy physics. However, universally simulating their interactions is arguably one of the largest challenges, because of the difficulties arising from an...

journal_title：Nature communications

authors： Barends R,Lamata L,Kelly J,García-Álvarez L,Fowler AG,Megrant A,Jeffrey E,White TC,Sank D,Mutus JY,Campbell B,Chen Y,Chen Z,Chiaro B,Dunsworth A,Hoi IC,Neill C,O'Malley PJ,Quintana C,Roushan P,Vainsencher A,Wenn

更新日期：2015-07-08 00:00:00

abstract：:Providing high performance electrical nano-interconnects for micro-nano electronics that are robust in harsh environments is highly demanded. Today, electrical nano-interconnects based on metallic nanowires, e.g. Ag and Cu, are limited by their positive physicochemical reactivity and ductility under large strain (i.e....

journal_title：Nature communications

authors： Sun Y,Sun B,He J,Yang G,Wang C

更新日期：2020-01-31 00:00:00

abstract：:Understanding the emerging models of adaptive resistance is key to overcoming cancer chemotherapy failure. Using human breast cancer explants, in vitro cell lines, mouse in vivo studies and mathematical modelling, here we show that exposure to a taxane induces phenotypic cell state transition towards a favoured transi...

journal_title：Nature communications

authors： Goldman A,Majumder B,Dhawan A,Ravi S,Goldman D,Kohandel M,Majumder PK,Sengupta S

更新日期：2015-02-11 00:00:00

abstract：:A skullcap found in the Salkhit Valley in northeast Mongolia is, to our knowledge, the only Pleistocene hominin fossil found in the country. It was initially described as an individual with possible archaic affinities, but its ancestry has been debated since the discovery. Here, we determine the age of the Salkhit sku...

journal_title：Nature communications

authors： Devièse T,Massilani D,Yi S,Comeskey D,Nagel S,Nickel B,Ribechini E,Lee J,Tseveendorj D,Gunchinsuren B,Meyer M,Pääbo S,Higham T

更新日期：2019-01-30 00:00:00

abstract：:Chemical functionalization is one of the most powerful and widely used strategies to control the properties of nanomaterials, particularly in the field of graphene. However, the ill-defined structure of the present functionalized graphene inhibits atomically precise structural characterization and structure-correlated...

journal_title：Nature communications

authors： Tan YZ,Yang B,Parvez K,Narita A,Osella S,Beljonne D,Feng X,Müllen K

更新日期：2013-01-01 00:00:00

abstract：:In nature, individual cells contain multiple isolated compartments in which cascade enzymatic reactions occur to form essential biological products with high efficiency. Here, we report a cell-inspired design of functional hydrogel particles with multiple compartments, in which different enzymes are spatially immobili...

journal_title：Nature communications

authors： Tan H,Guo S,Dinh ND,Luo R,Jin L,Chen CH

更新日期：2017-09-22 00:00:00

abstract：:The cellular mechanisms driving cardiac tissue formation remain poorly understood, largely due to the structural and functional complexity of the heart. It is unclear whether newly generated myocytes originate from cardiac stem/progenitor cells or from pre-existing cardiomyocytes that re-enter the cell cycle. Here, we...

journal_title：Nature communications

authors： Sereti KI,Nguyen NB,Kamran P,Zhao P,Ranjbarvaziri S,Park S,Sabri S,Engel JL,Sung K,Kulkarni RP,Ding Y,Hsiai TK,Plath K,Ernst J,Sahoo D,Mikkola HKA,Iruela-Arispe ML,Ardehali R

更新日期：2018-02-21 00:00:00

abstract：:Development of acute experimental autoimmune encephalomyelitis (EAE) depends on Th17 cells expressing the nuclear factor NR4A2. However, in mice lacking NR4A2 in T cells, a late-onset disease is still inducible, despite a great reduction in acute inflammation. We here reveal that development of this late onset disease...

journal_title：Nature communications

authors： Raveney BJ,Oki S,Hohjoh H,Nakamura M,Sato W,Murata M,Yamamura T

更新日期：2015-10-05 00:00:00

abstract：:The nitrogen-vacancy (NV) centre in diamond is a promising candidate for a solid-state qubit. However, its charge state is known to be unstable, discharging from the qubit state NV(-) into the neutral state NV(0) under various circumstances. Here we demonstrate that the charge state can be controlled by an electrolyti...

journal_title：Nature communications

authors： Grotz B,Hauf MV,Dankerl M,Naydenov B,Pezzagna S,Meijer J,Jelezko F,Wrachtrup J,Stutzmann M,Reinhard F,Garrido JA

更新日期：2012-03-06 00:00:00

abstract：:Malaria reduces host fitness and survival by pathogen-mediated damage and inflammation. Disease tolerance mechanisms counter these negative effects without decreasing pathogen load. Here, we demonstrate that in four different mouse models of malaria, adrenal hormones confer disease tolerance and protect against early ...

journal_title：Nature communications

authors： Vandermosten L,Pham TT,Knoops S,De Geest C,Lays N,Van der Molen K,Kenyon CJ,Verma M,Chapman KE,Schuit F,De Bosscher K,Opdenakker G,Van den Steen PE

更新日期：2018-10-30 00:00:00

abstract：:The original version of this Article contained an error in Figure 4. In panel a, the colour code for hot and cold clusters was inadvertently inverted. In the correct version of panel a, the hot clusters are blue and the cold clusters are yellow. This error has now been corrected in both the PDF and HTML versions of th...

journal_title：Nature communications

authors： Chakravarthy A,Furness A,Joshi K,Ghorani E,Ford K,Ward MJ,King EV,Lechner M,Marafioti T,Quezada SA,Thomas GJ,Feber A,Fenton TR

更新日期：2018-11-02 00:00:00

abstract：:Full-carbon electronics at the scale of several angstroms is an expeimental challenge, which could be overcome by exploiting the versatility of carbon allotropes. Here, we investigate charge transport through graphene/single-fullerene/graphene hybrid junctions using a single-molecule manipulation technique. Such sub-n...

journal_title：Nature communications

authors： Tan Z,Zhang D,Tian HR,Wu Q,Hou S,Pi J,Sadeghi H,Tang Z,Yang Y,Liu J,Tan YZ,Chen ZB,Shi J,Xiao Z,Lambert C,Xie SY,Hong W

更新日期：2019-04-15 00:00:00

abstract：:Hedgehog (Hh) signalling regulates embryonic development and adult tissue homoeostasis. Mutations of its pathway components including Suppressor of Fused (Sufu) and Gli/Ci predispose to cancers and congenital anomalies. The Sufu-Gli protein complex occupies a central position in the vertebrate Hh signalling pathway, e...

journal_title：Nature communications

authors： Zhang Y,Fu L,Qi X,Zhang Z,Xia Y,Jia J,Jiang J,Zhao Y,Wu G

更新日期：2013-01-01 00:00:00

abstract：:According to the clonal evolution model, tumour growth is driven by competing subclones in somatically evolving cancer cell populations, which gives rise to genetically heterogeneous tumours. Here we present a comparative targeted deep-sequencing approach combined with a customised statistical algorithm, called deepSN...

journal_title：Nature communications

authors： Gerstung M,Beisel C,Rechsteiner M,Wild P,Schraml P,Moch H,Beerenwinkel N

更新日期：2012-05-01 00:00:00

abstract：:The Victoria microplate between the Eastern and Western Branches of the East African Rift System is one of the largest continental microplates on Earth. In striking contrast to its neighboring plates, Victoria rotates counterclockwise with respect to Nubia. The underlying cause of this distinctive rotation has remaine...

journal_title：Nature communications

authors： Glerum A,Brune S,Stamps DS,Strecker MR

更新日期：2020-06-08 00:00:00

abstract：:In 1927, J.B.S. Haldane reasoned that the probability of fixation of new beneficial alleles is twice their fitness effect. This result, later generalized by M. Kimura, has since become the cornerstone of modern population genetics. There is no experimental test of Haldane's insight that new beneficial alleles are lost...

journal_title：Nature communications

authors： Chelo IM,Nédli J,Gordo I,Teotónio H

更新日期：2013-01-01 00:00:00