Gelation process visualized by aggregation-induced emission fluorogens.

abstract：:Coupling between vibrational modes is essential for energy transfer and dissipation in condensed matter. For water, different O-H stretch modes are known to be very strongly coupled both within and between water molecules, leading to ultrafast dissipation and delocalization of vibrational energy. In contrast, the info...

journal_title：Nature communications

authors： Yu CC,Chiang KY,Okuno M,Seki T,Ohto T,Yu X,Korepanov V,Hamaguchi HO,Bonn M,Hunger J,Nagata Y

更新日期：2020-11-25 00:00:00

abstract：:Compartmentalization of the gut microbiota is thought to be important to system function, but the extent of spatial organization in the gut ecosystem remains poorly understood. Here, we profile the murine colonic microbiota along longitudinal and lateral axes using laser capture microdissection. We found fine-scale sp...

journal_title：Nature communications

authors： Riva A,Kuzyk O,Forsberg E,Siuzdak G,Pfann C,Herbold C,Daims H,Loy A,Warth B,Berry D

更新日期：2019-09-25 00:00:00

abstract：:Band-inverted electron-hole bilayers support quantum spin Hall insulator and exciton condensate phases. Interest in quantum spin Hall effect in these systems has recently put them in the spotlight. We investigate such a bilayer in an external magnetic field. We show that the interlayer correlations lead to formation o...

journal_title：Nature communications

authors： Pikulin DI,Silvestrov PG,Hyart T

更新日期：2016-01-25 00:00:00

abstract：:Many porous materials are damaged by pressure exerted by salt crystals growing in their pores. This is a serious issue in conservation science, geomorphology, geotechnical engineering and concrete materials science. In all cases, a central question is whether crystallization pressure will cause damage. Here we present...

journal_title：Nature communications

authors： Flatt RJ,Caruso F,Sanchez AM,Scherer GW

更新日期：2014-09-11 00:00:00

abstract：:Current approaches to monitor and quantify cell division in live cells, and reliably distinguish between acytokinesis and endoreduplication, are limited and complicate determination of stem cell pool identities. Here we overcome these limitations by generating an in vivo reporter system using the scaffolding protein a...

journal_title：Nature communications

authors： Hesse M,Raulf A,Pilz GA,Haberlandt C,Klein AM,Jabs R,Zaehres H,Fügemann CJ,Zimmermann K,Trebicka J,Welz A,Pfeifer A,Röll W,Kotlikoff MI,Steinhäuser C,Götz M,Schöler HR,Fleischmann BK

更新日期：2012-01-01 00:00:00

abstract：:It is generally believed that the remarkable sensitivity and frequency selectivity of mammalian hearing depend on outer hair cell-generated force, which amplifies sound-induced vibrations inside the cochlea. This 'reverse transduction' force production has never been demonstrated experimentally, however, in the living...

journal_title：Nature communications

authors： Ren T,He W,Barr-Gillespie PG

更新日期：2016-01-06 00:00:00

abstract：:The mechanisms underlying how cells subjected to genotoxic stress reestablish reduction-oxidation (redox) homeostasis to scavenge genotoxic stress-induced reactive oxygen species (ROS), which maintains the physiological function of cellular processes and cell survival, remain unclear. Herein, we report that, via a TCF...

journal_title：Nature communications

authors： Cao L,Wu G,Zhu J,Tan Z,Shi D,Wu X,Tang M,Li Z,Hu Y,Zhang S,Yu R,Mo S,Wu J,Song E,Li M,Song L,Li J

更新日期：2019-08-21 00:00:00

abstract：:Resident tissue macrophages (RTM) can fulfill various tasks during development, homeostasis, inflammation and repair. In the lung, non-alveolar RTM, called interstitial macrophages (IM), importantly contribute to tissue homeostasis but remain little characterized. Here we show, using single-cell RNA-sequencing (scRNA-...

journal_title：Nature communications

authors： Schyns J,Bai Q,Ruscitti C,Radermecker C,De Schepper S,Chakarov S,Farnir F,Pirottin D,Ginhoux F,Boeckxstaens G,Bureau F,Marichal T

更新日期：2019-09-03 00:00:00

abstract：:Magnetic skyrmion, a topologically stable spin-swirling object, can host emergent electromagnetism, as exemplified by the topological Hall effect and electric-current-driven skyrmion motion. To achieve efficient manipulation of nano-sized functional spin textures, it is imperative to exploit the resonant motion of sky...

journal_title：Nature communications

authors： Okamura Y,Kagawa F,Mochizuki M,Kubota M,Seki S,Ishiwata S,Kawasaki M,Onose Y,Tokura Y

更新日期：2013-01-01 00:00:00

abstract：:Parkinson's disease (PD) and Multiple System Atrophy (MSA) are clinically distinctive diseases that feature a common neuropathological hallmark of aggregated α-synuclein. Little is known about how differences in α-synuclein aggregate structure affect disease phenotype. Here, we amplified α-synuclein aggregates from PD...

journal_title：Nature communications

authors： Strohäker T,Jung BC,Liou SH,Fernandez CO,Riedel D,Becker S,Halliday GM,Bennati M,Kim WS,Lee SJ,Zweckstetter M

更新日期：2019-12-04 00:00:00

abstract：:The hypothalamic suprachiasmatic (SCN) clock contains several neurochemically defined cell groups that contribute to the genesis of circadian rhythms. Using cell-specific and genetically targeted approaches we have confirmed an indispensable role for vasoactive intestinal polypeptide-expressing SCN (SCNVIP) neurons, i...

journal_title：Nature communications

authors： Todd WD,Venner A,Anaclet C,Broadhurst RY,De Luca R,Bandaru SS,Issokson L,Hablitz LM,Cravetchi O,Arrigoni E,Campbell JN,Allen CN,Olson DP,Fuller PM

更新日期：2020-09-02 00:00:00

abstract：:The antiquity and global abundance of the enzyme, RuBisCO, attests to the crucial and longstanding role it has played in the biogeochemical cycles of Earth over billions of years. The counterproductive oxygenase activity of RuBisCO has persisted over billions of years of evolution, despite its competition with the car...

journal_title：Nature communications

authors： Shih PM,Occhialini A,Cameron JC,Andralojc PJ,Parry MA,Kerfeld CA

更新日期：2016-01-21 00:00:00

abstract：:When a thin film of active, nematic microtubules and kinesin motor clusters is confined on the surface of a vesicle, four +1/2 topological defects oscillate in a periodic manner between tetrahedral and planar arrangements. Here a theoretical description of nematics, coupled to the relevant hydrodynamic equations, is p...

journal_title：Nature communications

authors： Zhang R,Zhou Y,Rahimi M,de Pablo JJ

更新日期：2016-11-21 00:00:00

abstract：:There is increasing interest in transplantation of human stem cells for therapeutic purposes. It would benefit future application if one could achieve their long-term acceptance and functional differentiation in allogeneic hosts using minimal immunosuppression. Allogeneic stem cell transplants differ from conventional...

journal_title：Nature communications

authors： Lui KO,Howie D,Ng SW,Liu S,Chien KR,Waldmann H

更新日期：2014-12-01 00:00:00

abstract：:Small interfering RNAs (siRNAs) conjugated to a trivalent N-acetylgalactosamine (GalNAc) ligand are being evaluated in investigational clinical studies for a variety of indications. The typical development candidate selection process includes evaluation of the most active compounds for toxicity in rats at pharmacologi...

journal_title：Nature communications

authors： Janas MM,Schlegel MK,Harbison CE,Yilmaz VO,Jiang Y,Parmar R,Zlatev I,Castoreno A,Xu H,Shulga-Morskaya S,Rajeev KG,Manoharan M,Keirstead ND,Maier MA,Jadhav V

更新日期：2018-02-19 00:00:00

abstract：:CD4(+) Th17 are heterogeneous in terms of cytokine production and capacity to initiate autoimmune diseases, such as experimental autoimmune encephalomyelitis (EAE). Here we demonstrate that experimental priming of encephalitogenic Th cells expressing RORγt and T-bet and producing IL-17A, IFN-γ and GM-CSF but not IL-10...

journal_title：Nature communications

authors： Ronchi F,Basso C,Preite S,Reboldi A,Baumjohann D,Perlini L,Lanzavecchia A,Sallusto F

更新日期：2016-05-18 00:00:00

abstract：:The efficiencies of perovskite solar cells (PSCs) are now reaching such consistently high levels that scalable manufacturing at low cost is becoming critical. However, this remains challenging due to the expensive hole-transporting materials usually employed, and difficulties associated with the scalable deposition of...

journal_title：Nature communications

authors： Wu WQ,Wang Q,Fang Y,Shao Y,Tang S,Deng Y,Lu H,Liu Y,Li T,Yang Z,Gruverman A,Huang J

更新日期：2018-04-24 00:00:00

abstract：:The original version of this Article contained an error in the author affiliations. Xiaochun Yu was incorrectly associated with College of Life Sciences, Hebei University, Baoding 071000 Hebei, China.This has now been corrected in both the PDF and HTML versions of the Article. ...

journal_title：Nature communications

authors： Wang J,Yuan Z,Cui Y,Xie R,Yang G,Kassab MA,Wang M,Ma Y,Wu C,Yu X,Liu X

更新日期：2019-01-08 00:00:00

abstract：:Regaining the function of an impaired limb is highly desirable in paralyzed individuals. One possible avenue to achieve this goal is to bridge the interrupted pathway between preserved neural structures and muscles using a brain-computer interface. Here, we demonstrate that monkeys with subcortical stroke were able to...

journal_title：Nature communications

authors： Kato K,Sawada M,Nishimura Y

更新日期：2019-10-16 00:00:00

abstract：:Bipolar spindle assembly is a critical control point for initiation of mitosis through nucleation and organization of spindle microtubules and is regulated by kinesin-like proteins. In fission yeast, the kinesin-14 Pkl1 binds the γ-tubulin ring complex (γ-TuRC) microtubule-organizing centre at spindle poles and can al...

journal_title：Nature communications

authors： Olmsted ZT,Colliver AG,Riehlman TD,Paluh JL

更新日期：2014-10-28 00:00:00

abstract：:The costs for solar photovoltaics, wind, and battery storage have dropped markedly since 2010, however, many recent studies and reports around the world have not adequately captured such dramatic decrease. Those costs are projected to decline further in the near future, bringing new prospects for the widespread penetr...

journal_title：Nature communications

authors： He G,Lin J,Sifuentes F,Liu X,Abhyankar N,Phadke A

更新日期：2020-05-19 00:00:00

abstract：:There is a multi-billion dollar global industry dedicated to feeding wild birds in residential gardens. This extraordinary boost to food resources is almost certainly reshaping entire bird communities, yet the large-scale, long-term impacts on community ecology remain unknown. Here we reveal a 40-year transformation o...

journal_title：Nature communications

authors： Plummer KE,Risely K,Toms MP,Siriwardena GM

更新日期：2019-05-21 00:00:00

abstract：:The original version of this article contained an error in the spelling of the author Christian A.M. Wilson, which was incorrectly given as Christian M.A. Wilson. This has now been corrected in both the PDF and HTML versions of the article. ...

journal_title：Nature communications

authors： Bustamante A,Sotelo-Campos J,Guerra DG,Floor M,Wilson CAM,Bustamante C,Báez M

更新日期：2017-12-14 00:00:00

abstract：:Colloidal interactions in nematic liquid crystals can be described as interactions between elastic multipoles that depend on particle shape, topology, chirality, boundary conditions and induced topological defects. Here, we describe a nematic colloidal system consisting of mesostructures of gold capable of inducing el...

journal_title：Nature communications

authors： Yuan Y,Tasinkevych M,Smalyukh II

更新日期：2020-01-10 00:00:00

abstract：:Quantum technology promises revolutionizing applications in information processing, communications, sensing and modelling. However, efficient on-demand cooling of the functional quantum degrees of freedom remains challenging in many solid-state implementations, such as superconducting circuits. Here we demonstrate dir...

journal_title：Nature communications

authors： Tan KY,Partanen M,Lake RE,Govenius J,Masuda S,Möttönen M

更新日期：2017-05-08 00:00:00

abstract：:Gluconeogenesis is a fundamental feature of hepatocytes. Whether this gluconeogenic activity is also present in malignant hepatocytes remains unexplored. A better understanding of this biological process may lead to novel therapeutic strategies. Here we show that gluconeogenesis is not present in mouse or human malign...

journal_title：Nature communications

authors： Ma R,Zhang W,Tang K,Zhang H,Zhang Y,Li D,Li Y,Xu P,Luo S,Cai W,Ji T,Katirai F,Ye D,Huang B

更新日期：2013-01-01 00:00:00

abstract：:Turgor pressure plays pivotal roles in the growth and movement of walled cells that make up plants and fungi. However, the molecular mechanisms regulating turgor pressure and the coordination between turgor pressure and cell wall remodelling for cell growth remain poorly understood. Here, we report the characterizatio...

journal_title：Nature communications

authors： Chen LY,Shi DQ,Zhang WJ,Tang ZS,Liu J,Yang WC

更新日期：2015-01-16 00:00:00

abstract：:Although the pharmacological effects of fibroblast growth factor 21 (FGF21) are well-documented, uncertainty about its role in regulating excessive energy intake remains. Here, we show that FGF21 improves systemic insulin sensitivity by promoting the healthy expansion of subcutaneous adipose tissue (SAT). Serum FGF21 ...

journal_title：Nature communications

authors： Li H,Wu G,Fang Q,Zhang M,Hui X,Sheng B,Wu L,Bao Y,Li P,Xu A,Jia W

更新日期：2018-01-18 00:00:00

abstract：:Clostridium difficile is the leading cause of pseudomembranous colitis in hospitalized patients. C. difficile enterotoxins TcdA and TcdB promote this inflammatory condition via a cytotoxic response on intestinal epithelial cells (IECs), but the underlying mechanisms are incompletely understood. Additionally, TcdA and ...

journal_title：Nature communications

authors： Saavedra PHV,Huang L,Ghazavi F,Kourula S,Vanden Berghe T,Takahashi N,Vandenabeele P,Lamkanfi M

更新日期：2018-11-19 00:00:00

abstract：:Homologous recombination (HR) mediates the error-free repair of DNA double-strand breaks to maintain genomic stability. Here we characterize C17orf53/MCM8IP, an OB-fold containing protein that binds ssDNA, as a DNA repair factor involved in HR. MCM8IP-deficient cells exhibit HR defects, especially in long-tract gene c...

journal_title：Nature communications

authors： Huang JW,Acharya A,Taglialatela A,Nambiar TS,Cuella-Martin R,Leuzzi G,Hayward SB,Joseph SA,Brunette GJ,Anand R,Soni RK,Clark NL,Bernstein KA,Cejka P,Ciccia A

更新日期：2020-06-11 00:00:00