Abstract:
:Turgor pressure plays pivotal roles in the growth and movement of walled cells that make up plants and fungi. However, the molecular mechanisms regulating turgor pressure and the coordination between turgor pressure and cell wall remodelling for cell growth remain poorly understood. Here, we report the characterization of Arabidopsis TurgOr regulation Defect 1 (TOD1), which is preferentially expressed in pollen tubes and silique guard cells. We demonstrate that TOD1 is a Golgi-localized alkaline ceramidase. tod1 mutant pollen tubes have higher turgor than wild type and show growth retardation both in pistils and in agarose medium. In addition, tod1 guard cells are insensitive to abscisic acid (ABA)-induced stomatal closure, whereas sphingosine-1-phosphate, a putative downstream component of ABA signalling and product of alkaline ceramidases, promotes closure in both wild type and tod1. Our data suggest that TOD1 acts in turgor pressure regulation in both guard cells and pollen tubes.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Chen LY,Shi DQ,Zhang WJ,Tang ZS,Liu J,Yang WCdoi
10.1038/ncomms7030subject
Has Abstractpub_date
2015-01-16 00:00:00pages
6030issn
2041-1723pii
ncomms7030journal_volume
6pub_type
杂志文章abstract::Flexible, wearable sensing devices can yield important information about the underlying physiology of a human subject for applications in real-time health and fitness monitoring. Despite significant progress in the fabrication of flexible biosensors that naturally comply with the epidermis, most designs measure only a...
journal_title:Nature communications
pub_type: 临床试验,杂志文章
doi:10.1038/ncomms11650
更新日期:2016-05-23 00:00:00
abstract::Hydrogen can facilitate the detachment of protective oxide layer off metals and alloys. The degradation is usually exacerbated at elevated temperatures in many industrial applications; however, its origin remains poorly understood. Here by heating hydrogenated aluminium inside an environmental transmission electron mi...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms14564
更新日期:2017-02-20 00:00:00
abstract::The original version of this Article contained an error in the spelling of the author Woochul Song, which was incorrectly given as Woochul C. Song. This has been corrected in both the PDF and HTML versions of the Article. ...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41467-018-05447-3
更新日期:2018-08-14 00:00:00
abstract::Omniphobic membranes are attractive for membrane distillation (MD) because of their superior wetting resistance. However, a design framework for MD membrane remains incomplete, due to the complexity of omniphobic membrane fabrication and the lack of fundamental relationship between wetting resistance and water vapor p...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-11209-6
更新日期:2019-07-19 00:00:00
abstract::Owing to their pathogenical role and unique ability to exist both as soluble proteins and transmembrane complexes, pore-forming toxins (PFTs) have been a focus of microbiologists and structural biologists for decades. PFTs are generally secreted as water-soluble monomers and subsequently bind the membrane of target ce...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12062
更新日期:2016-07-13 00:00:00
abstract::The endoplasmic reticulum-mitochondria encounter structure (ERMES) connects the mitochondrial outer membrane with the ER. Multiple functions have been linked to ERMES, including maintenance of mitochondrial morphology, protein assembly and phospholipid homeostasis. Since the mitochondrial distribution and morphology p...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms13021
更新日期:2016-10-10 00:00:00
abstract::Supercooled liquids exhibit spatial heterogeneity in the dynamics of their fluctuating atomic arrangements. The length and time scales of the heterogeneous dynamics are central to the glass transition and influence nucleation and growth of crystals from the liquid. Here, we report direct experimental visualization of ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03604-2
更新日期:2018-03-19 00:00:00
abstract::Mitochondria are essential cellular organelles for generation of energy and their dysfunction may cause diabetes, Parkinson's disease and multi-systemic failure marked by failure to thrive, gastrointestinal problems, lactic acidosis and early lethality. Disease-associated mitochondrial mutations often affect component...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3886
更新日期:2013-01-01 00:00:00
abstract::Chikungunya virus (CHIKV) is a globally spreading alphavirus against which there is no commercially available vaccine or therapy. Here we use a genome-wide siRNA screen to identify 156 proviral and 41 antiviral host factors affecting CHIKV replication. We analyse the cellular pathways in which human proviral genes are...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms11320
更新日期:2016-05-12 00:00:00
abstract::Bacterial infections and antibiotic resistance, particularly by Gram-negative pathogens, have become a global healthcare crisis. We report the design of a class of cationic antimicrobial polymers that cluster local facial amphiphilicity from repeating units to enhance interactions with bacterial membranes without requ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-07651-7
更新日期:2018-12-07 00:00:00
abstract::Formation of domain walls in ferroelectrics is not energetically favourable in low-dimensional systems. Instead, vortex-type structures are formed that are driven by depolarization fields occurring in such systems. Consequently, polarization vortices have only been experimentally found in systems in which these fields...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms13484
更新日期:2016-11-16 00:00:00
abstract::The synergistic interaction among different components in complex catalysts is one of the crucial factors in determining catalytic performance. Here we report the interactions among the three components in controlling the catalytic performance of Cu-ZnO-ZrO2 (CZZ) catalyst for CO2 hydrogenation to methanol. The in sit...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09072-6
更新日期:2019-03-11 00:00:00
abstract::Insects have presented human society with some of its greatest development challenges by spreading diseases, consuming crops and damaging infrastructure. Despite the massive human and financial toll of invasive insects, cost estimates of their impacts remain sporadic, spatially incomplete and of questionable quality. ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12986
更新日期:2016-10-04 00:00:00
abstract::There are established associations between advanced paternal age and offspring risk for psychiatric and developmental disorders. These are commonly attributed to genetic mutations, especially de novo single nucleotide variants (dnSNVs), that accumulate with increasing paternal age. However, the actual magnitude of ris...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-11039-6
更新日期:2019-07-10 00:00:00
abstract::Cancer evolution is fueled by epigenetic as well as genetic diversity. In chronic lymphocytic leukemia (CLL), intra-tumoral DNA methylation (DNAme) heterogeneity empowers evolution. Here, to comprehensively study the epigenetic dimension of cancer evolution, we integrate DNAme analysis with histone modification mappin...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09645-5
更新日期:2019-04-23 00:00:00
abstract::During epithelial morphogenesis, cell contacts (junctions) are constantly remodeled by mechanical forces that work against adhesive forces. E-cadherin complexes play a pivotal role in this process by providing persistent cell adhesion and by transmitting mechanical tension. In this context, it is unclear how mechanica...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-07448-8
更新日期:2018-11-27 00:00:00
abstract::Continuous cycles of nucleocytoplasmic transport require disassembly of transport receptor/Ran-GTP complexes in the cytoplasm. A basic disassembly mechanism in all eukaryotes depends on soluble RanGAP and RanBP1. In vertebrates, a significant fraction of RanGAP1 stably interacts with the nucleoporin RanBP2 at a bindin...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms11482
更新日期:2016-05-10 00:00:00
abstract::The practices of synthetic biology are being integrated into 'multiscale' designs enabling two-way communication across organic and inorganic information substrates in biological, digital and cyber-physical system integrations. Novel applications of 'bio-informational' engineering will arise in environmental monitorin...
journal_title:Nature communications
pub_type: 杂志文章,评审
doi:10.1038/s41467-020-20764-2
更新日期:2021-01-15 00:00:00
abstract::Nuclear magnetic resonance (NMR) spectroscopy is a powerful method for analyzing the chemical composition and molecular structure of materials. At the nanometer scale, NMR has the prospect of mapping the atomic-scale structure of individual molecules, provided a method that can sensitively detect single nuclei and mea...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-07121-0
更新日期:2018-11-08 00:00:00
abstract::Patterns in biomass production are determined by resource input (productivity) and trophic transfer efficiency. At fixed resource input, variation in consumer biomass production has been related to food quality, metabolic type and diversity among species. In contrast, intraspecific variation in individual body size be...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms7441
更新日期:2015-03-04 00:00:00
abstract::Activation of the Hippo pathway effector Yap underlies many liver cancers, however no germline or somatic mutations have been identified. Autophagy maintains essential metabolic functions of the liver, and autophagy-deficient murine models develop benign adenomas and hepatomegaly, which have been attributed to activat...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-07338-z
更新日期:2018-11-23 00:00:00
abstract::SIRT1, the founding member of the mammalian family of seven NAD(+)-dependent sirtuins, is composed of 747 amino acids forming a catalytic domain and extended N- and C-terminal regions. We report the design and characterization of an engineered human SIRT1 construct (mini-hSIRT1) containing the minimal structural eleme...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms8645
更新日期:2015-07-02 00:00:00
abstract::Purely organic room temperature phosphorescence (RTP) has attracted wide attention recently due to its various application potentials. However, ultralong RTP (URTP) with high efficiency is still rarely achieved. Herein, by dissolving 1,8-naphthalic anhydride in certain organic solid hosts, URTP with a lifetime of over...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13048-x
更新日期:2019-11-14 00:00:00
abstract::Bell correlations are a foundational demonstration of how quantum entanglement contradicts the classical notion of local realism. Rigorous validation of quantum nonlocality have only been achieved between solid-state electron spins, internal states of trapped atoms, and photon polarisations, all weakly coupling to gra...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-12192-8
更新日期:2019-10-01 00:00:00
abstract::Cell fate determination requires the cooperation between extrinsic signals and intrinsic molecules including transcription factors as well as epigenetic regulators. Nevertheless, how neural fate commitment is regulated by epigenetic modifications remains largely unclear. Here we show that transient histone deacetylati...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms7830
更新日期:2015-04-23 00:00:00
abstract::Despite the pursuit of quantum advantages in various applications, the power of quantum computers in executing neural network has mostly remained unknown, primarily due to a missing tool that effectively designs a neural network suitable for quantum circuit. Here, we present a neural network and quantum circuit co-des...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-20729-5
更新日期:2021-01-25 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Nature communications
pub_type: 已发布勘误
doi:10.1038/s41467-019-13715-z
更新日期:2019-12-06 00:00:00
abstract::Transcription of eukaryotic protein-coding genes requires passage of RNA polymerase II (Pol II) through nucleosomes, but it is unclear how this is achieved. Here we report the cryo-EM structure of transcribing Saccharomyces cerevisiae Pol II engaged with a downstream nucleosome core particle at an overall resolution o...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-07870-y
更新日期:2018-12-21 00:00:00
abstract::Coordination of ciliary beating is essential to ensure mucus clearance in the airway tract. The orientation and synchronization of ciliary motion responds in part to the organization of the underlying cytoskeletal networks. Using electron tomography on mouse trachea, we show that basal bodies are collectively hooked a...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms5888
更新日期:2014-09-12 00:00:00
abstract::Generation and recombination of electrons and holes in organic solar cells occurs via charge transfer states located at the donor/acceptor interface. The energy of these charge transfer states is a crucial factor for the attainable open-circuit voltage and its correct determination is thus of utmost importance for a d...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-05987-8
更新日期:2018-09-07 00:00:00