Better Service by Doing Less: Introducing De-implementation Research in HIV.

abstract：:Neurocognitive compromise, a common sequela of HIV infection, ranges in severity from minor motor and information-processing speed decrements to severely incapacitating symptoms that affect functional independence. However, with the emergence of highly active antiretroviral therapy (HAART), neurocognitive phenotypes h...

journal_title：Current HIV/AIDS reports

authors： Foley J,Ettenhofer M,Wright M,Hinkin CH

更新日期：2008-11-01 00:00:00

abstract：:Nine months of daily isoniazid is efficacious in treating latent M. tuberculosis infection, but completion rates are low, limiting treatment effectiveness. In 2011, three important studies were published involving novel regimens for the treatment of latent M. tuberculosis infection. At least 36 months of isoniazid was...

journal_title：Current HIV/AIDS reports

authors： Person AK,Sterling TR

更新日期：2012-09-01 00:00:00

abstract：:Recent policies, guidelines, and laws reflect promising preliminary outcomes among transplant recipients with HIV infection, and ethical analyses suggest that it is not justifiable to deny solid organ transplantation based solely on HIV-infection status. These studies consistently describe stable HIV disease following...

journal_title：Current HIV/AIDS reports

authors： Roland ME,Stock PG

更新日期：2006-09-01 00:00:00

abstract：:The AIDS epidemic continues its unrelentless expansion. According to the Joint United Nations Programme on HIV/AIDS, there are more than 40 million people living with HIV, and more than 15,000 new infections occur every day. One approach to curbing HIV is the development of topical microbicidal agents or microbicides....

journal_title：Current HIV/AIDS reports

authors： Doncel G,Mauck C

更新日期：2004-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This review summarizes recent literature defining tissue-resident memory T cells (TRM) and discusses implications for HIV pathogenesis, vaccines, and eradication efforts. RECENT FINDINGS:Investigations using animal models and human tissues have identified a TRM transcriptional profile and elucidated ...

journal_title：Current HIV/AIDS reports

authors： Shacklett BL,Ferre AL,Kiniry BE

更新日期：2020-04-01 00:00:00

abstract：:Substance users are at elevated risk for HIV. HIV researchers, particularly at the intersection of HIV and substance use, have requested new methods to better understand and address this important area. New technologies, such as social media and mobile applications, are increasingly being used as research tools in stu...

journal_title：Current HIV/AIDS reports

authors： Young SD,Swendeman D,Holloway IW,Reback CJ,Kao U

更新日期：2015-12-01 00:00:00

abstract：:Due to life-enhancing effects of antiretroviral therapy, HIV-positive persons have the potential for long life comparable to their uninfected peers. Older women (age 50+) living with HIV (OWLH) are often an under-recognized aging group. We conducted a systematic review to examine psychosocial factors that impact how O...

journal_title：Current HIV/AIDS reports

authors： Rubtsova AA,Kempf MC,Taylor TN,Konkle-Parker D,Wingood GM,Holstad MM

更新日期：2017-02-01 00:00:00

abstract：:Sustained retention represents an enduring and evolving challenge to HIV treatment programs in Africa. We present a theoretical framework for sustained retention borrowing from ecologic principles of sustainability and dynamic adaptation. We posit that sustained retention from the patient perspective is dependent on t...

journal_title：Current HIV/AIDS reports

authors： Roy M,Czaicki N,Holmes C,Chavan S,Tsitsi A,Odeny T,Sikazwe I,Padian N,Geng E

更新日期：2016-06-01 00:00:00

abstract：:Increased access to testing and treatment means HIV can be managed as a chronic illness, though successful management requires continued engagement with the health care system. Most of the global HIV burden is in sub-Saharan Africa where rates of new infections are consistently higher in women versus men. Pregnancy is...

journal_title：Current HIV/AIDS reports

authors： Psaros C,Remmert JE,Bangsberg DR,Safren SA,Smit JA

更新日期：2015-03-01 00:00:00

abstract：:The first association between HIV-1 infection and kidney disease was made in 1984 and much has been learned over the past 20 years. In recent years, more effective therapies for HIV-1 infection and its associated opportunistic infections have led to improved patient survival. However, with prolonged survival, morbidit...

journal_title：Current HIV/AIDS reports

authors： Cho ME,Kopp JB

更新日期：2004-09-01 00:00:00

abstract：:Due to the rapid expansion of first-line antiretroviral therapy in resource-limited settings (RLS), increasing numbers of people are living with HIV for prolonged periods of time. Treatment programs must now decide how to balance monitoring costs necessary to maximize health benefits for those already on treatment wit...

journal_title：Current HIV/AIDS reports

authors： Hosseinipour MC,Schechter M

更新日期：2010-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Aligning HIV treatment services with patient preferences can promote long-term engagement. A rising number of studies solicit such preferences using discrete choice experiments, but have not been systematically reviewed to seek generalizable insights. Using a systematic search, we identified eleven ch...

journal_title：Current HIV/AIDS reports

authors： Eshun-Wilson I,Kim HY,Schwartz S,Conte M,Glidden DV,Geng EH

更新日期：2020-10-01 00:00:00

abstract：PURPOSE OF REVIEW:End-stage organ disease prevalence is increasing among HIV-infected (HIV+) individuals. Trial and registry data confirm that solid organ transplantation (SOT) is efficacious in this population. Optimizing access to transplant and decreasing complications represent active frontiers. RECENT FINDINGS:HI...

journal_title：Current HIV/AIDS reports

authors： Werbel WA,Durand CM

更新日期：2019-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review aims to describe the epidemiology of HIV among female sex workers (FSWs) in China over the past decade, to summarize current gaps in knowledge regarding risk factors, and to identify new directions for HIV prevention strategies. RECENT FINDINGS:We summarized national and regional levels o...

journal_title：Current HIV/AIDS reports

authors： Zhang H,Hsieh E,Wang L,Liao S

更新日期：2020-04-01 00:00:00

abstract：PURPOSE OF REVIEW:In the absence of antiretroviral therapy (ART), more than 50% of perinatally HIV-infected children die by 2 years of age. Early ART from infancy is therefore a global recommendation and significantly improves immune health, child survival, and disease outcome. However, even early treatment does not pr...

journal_title：Current HIV/AIDS reports

authors： Berendam SJ,Nelson AN,Goswami R,Persaud D,Haigwood NL,Chahroudi A,Fouda GG,Permar SR

更新日期：2020-06-01 00:00:00

abstract：:Combined antiretroviral therapy (CART) has turned HIV-infection to a treatable chronic disease during which many patients survive to middle and older age. However, they prematurely develop non-AIDS comorbidities such as cardiovascular disease, metabolic syndrome, diabetes, and HIV-associated neurocognitive disorders (...

journal_title：Current HIV/AIDS reports

authors： Monsuez JJ,Belin C,Bouchaud O

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF THE REVIEW:Early diagnosis and treatment of HIV following seroconversion improves individual and population health. Using published data on pre-treatment CD4 cell counts, we benchmarked the level of immunodeficiency at HIV diagnosis and ART initiation in the "real world" against those of the treatment and co...

journal_title：Current HIV/AIDS reports

authors： Nash D,Robertson M

更新日期：2019-08-01 00:00:00

abstract：:Neurocognitive impairment is common in people living with HIV and AIDS. Prior to highly active antiretroviral therapy (HAART), cognitive impairment primarily affected patients with advanced disease, and was a more rapidly progressive illness. With the use of HAART, cognitive impairment improved, along with the overall...

journal_title：Current HIV/AIDS reports

authors： Robinson-Papp J,Elliott KJ,Simpson DM

更新日期：2009-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Mental health disorders, especially depression, are prevalent among people living with HIV (PLWH) and are associated with cognitive impairment (CI) among HIV-uninfected (HIV-) individuals. We conducted a comprehensive review of the link between depression and cognition among PLWH. RECENT FINDINGS:Stu...

journal_title：Current HIV/AIDS reports

authors： Rubin LH,Maki PM

更新日期：2019-02-01 00:00:00

abstract：:Adolescents are critical to efforts to end the AIDS epidemic. Few national AIDS strategies explicitly program for children in their second decade of life. Adolescents (aged 10-19 years) are therefore largely invisible in global, regional, and country HIV and AIDS reports making it difficult to assess progress in this ...

journal_title：Current HIV/AIDS reports

authors： Kasedde S,Luo C,McClure C,Chandan U

更新日期：2013-06-01 00:00:00

abstract：:HIV may cause several forms of peripheral neuropathy, the most common of which is distal symmetric polyneuropathy (DSP) characterized by pain and sensory deficits in a stocking-glove distribution. The pathophysiology of DSP remains largely unknown but is thought to be related both to the neurotoxicity of HIV-through i...

journal_title：Current HIV/AIDS reports

authors： Stavros K,Simpson DM

更新日期：2014-09-01 00:00:00

abstract：:Despite impressive decreases in mortality and morbidity, significant adverse events have surfaced as a result of combination antiretroviral therapy (ART). They include lipoatrophy, or subcutaneous fat wasting of the face, arms, buttocks, or legs, which can be associated with central fat accumulation. Although the unde...

journal_title：Current HIV/AIDS reports

authors： Tungsiripat M,McComsey G

更新日期：2008-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The discovery of innate lymphoid cells (ILCs) over the past decade has reformed principles that were once thought to be exclusive to adaptive immunity. Here, we describe ILC nomenclature and function, and provide a survey of studies examining these cells in the context of HIV/SIV infections. Particula...

journal_title：Current HIV/AIDS reports

authors： Mudd JC,Brenchley JM

更新日期：2019-06-01 00:00:00

abstract：:An emerging body of evidence suggests that intergenerational sexual partnerships may increase risk of HIV acquisition among young men who have sex with men (YMSM). However, no studies have comprehensively evaluated literature in this area. We applied a scoping review methodology to explore the relationships between ag...

journal_title：Current HIV/AIDS reports

authors： Anema A,Marshall BD,Stevenson B,Gurm J,Montaner G,Small W,Roth EA,Lima VD,Montaner JS,Moore D,Hogg RS

更新日期：2013-12-01 00:00:00

abstract：:This article reviews the magnitude and spectrum of ocular complications of HIV infection in sub-Sahara Africa. A literature search was done using PubMed, Google, and UpToDate and by talking to ophthalmologists and HIV experts working in the region. Ocular complications of HIV infection, mostly retinal, are seen in 29%...

journal_title：Current HIV/AIDS reports

authors： Nkomazana O,Tshitswana D

更新日期：2008-08-01 00:00:00

abstract：:Generation of memory T cells, which mediate immunity against microbes and cancers, relies, for optimal activity, on the interactions of multiple cell types that are highly regulated through the expression of soluble factors and negative and positive receptors. Their disruption will lead to aberrant immune responses, w...

journal_title：Current HIV/AIDS reports

authors： El-Far M,Halwani R,Said E,Trautmann L,Doroudchi M,Janbazian L,Fonseca S,van Grevenynghe J,Yassine-Diab B,Sékaly RP,Haddad EK

更新日期：2008-02-01 00:00:00

abstract：:While combination antiretroviral therapy allows HIV-infected patients to have life expectancies similar to that of the general population, it may also contribute to the development of co-morbidities, such as cardiovascular disease and osteoporosis. Such complications could compromise long-term quality of life, especia...

journal_title：Current HIV/AIDS reports

authors： Eckard AR,Fowler SL,Haston JC,Dixon TC

更新日期：2016-08-01 00:00:00

abstract：:The role of voluntary counseling and testing (VCT)of HIV in resource-limited settings has recently broadened from primarily that of a prevention intervention to its identification as the key entry point into expanding access to life-saving antiretroviral therapy, additional HIV-specific medical care, and other support...

journal_title：Current HIV/AIDS reports

authors： Liechty CA

更新日期：2004-12-01 00:00:00

abstract：:The global HIV pandemic began to expand rapidly in southern Africa a decade later than was noted in central Africa, Europe, the Caribbean, and North America. Multiple factors played a role in this rapid expansion which led Southern Africa to become the most heavily afflicted region for HIV/AIDS globally. In this issue...

journal_title：Current HIV/AIDS reports

authors： Vermund SH,Sheldon EK,Sidat M

更新日期：2015-06-01 00:00:00

abstract：PURPOSE OF REVIEW:In this report, we review the need for point-of-care (POC) or near real-time testing for antiretrovirals, progress in the field, evidence for guiding implementation of these tests globally, and future directions in objective antiretroviral therapy (ART) or pre-exposure prophylaxis (PrEP) adherence mon...

journal_title：Current HIV/AIDS reports

authors： Drain PK,Bardon AR,Simoni JM,Cressey TR,Anderson P,Sevenler D,Olanrewaju AO,Gandhi M,Celum C

更新日期：2020-10-01 00:00:00