Evidence that specific and "general" control of ornithine carbamoyltransferase production occurs at the level of transcription in Saccharomyces cerevisiae.

Abstract:

:Ornithine carbamoyltransferase synthesis is subject to two major regulatory systems in Saccharomyces cerevisiae. One system is specific for the arginine biosynthetic enzymes, whereas the other appears to be general, acting on a variety of other amino acid pathways as well. We observed that the synthetic capacity for continued ornithine carbamoyltransferase synthesis had the same short half-life (ca. 5 to 7 min) whether repression of enzyme production was brought about by action of the specific or general control system. We present evidence suggesting that both control systems regulate accumulation or ornithine carbamoyltransferase-specific synthetic capacity, rather than modulating its expression.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Messenguy F,Cooper TG

doi

10.1128/JB.130.3.1253-1261.1977

subject

Has Abstract

pub_date

1977-06-01 00:00:00

pages

1253-61

issue

3

eissn

0021-9193

issn

1098-5530

journal_volume

130

pub_type

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