Identification of Nudix hydrolase family members with an antimutator role in Mycobacterium tuberculosis and Mycobacterium smegmatis.

Abstract:

:Mycobacterium tuberculosis and Mycobacterium smegmatis MutT1, MutT2, MutT3, and Rv3908 (MutT4) enzymes were screened for an antimutator role. Results indicate that both MutT1, in M. tuberculosis and M. smegmatis, and MutT4, in M. smegmatis, have that role. Furthermore, an 8-oxo-guanosine triphosphatase function for MutT1 and MutT2 is suggested.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Dos Vultos T,Blázquez J,Rauzier J,Matic I,Gicquel B

doi

10.1128/JB.188.8.3159-3161.2006

keywords:

subject

Has Abstract

pub_date

2006-04-01 00:00:00

pages

3159-61

issue

8

eissn

0021-9193

issn

1098-5530

pii

188/8/3159

journal_volume

188

pub_type

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