Nanoscale origins of creep in calcium silicate hydrates.

abstract：:Although chemically very simple, Fe2O3 is known to undergo a series of enigmatic structural, electronic and magnetic transformations at high pressures and high temperatures. So far, these transformations have neither been correctly described nor understood because of the lack of structural data. Here we report a syste...

journal_title：Nature communications

authors： Bykova E,Dubrovinsky L,Dubrovinskaia N,Bykov M,McCammon C,Ovsyannikov SV,Liermann HP,Kupenko I,Chumakov AI,Rüffer R,Hanfland M,Prakapenka V

更新日期：2016-02-11 00:00:00

abstract：:Human-pluripotent-stem-cell-derived kidney cells (hPSC-KCs) have important potential for disease modelling and regeneration. Whether the hPSC-KCs can reconstitute tissue-specific phenotypes is currently unknown. Here we show that hPSC-KCs self-organize into kidney organoids that functionally recapitulate tissue-specif...

journal_title：Nature communications

authors： Freedman BS,Brooks CR,Lam AQ,Fu H,Morizane R,Agrawal V,Saad AF,Li MK,Hughes MR,Werff RV,Peters DT,Lu J,Baccei A,Siedlecki AM,Valerius MT,Musunuru K,McNagny KM,Steinman TI,Zhou J,Lerou PH,Bonventre JV

更新日期：2015-10-23 00:00:00

abstract：:Isolators, or optical diodes, are devices enabling unidirectional light propagation by using non-reciprocal optical materials, namely materials able to break Lorentz reciprocity. The realization of isolators at terahertz frequencies is a very important open challenge made difficult by the intrinsically lossy propagati...

journal_title：Nature communications

authors： Tamagnone M,Moldovan C,Poumirol JM,Kuzmenko AB,Ionescu AM,Mosig JR,Perruisseau-Carrier J

更新日期：2016-04-06 00:00:00

abstract：:Sustainable food production in the context of climate change necessitates diversification of agriculture and a more efficient utilization of plant genetic resources. Fonio millet (Digitaria exilis) is an orphan African cereal crop with a great potential for dryland agriculture. Here, we establish high-quality genomic ...

journal_title：Nature communications

authors： Abrouk M,Ahmed HI,Cubry P,Šimoníková D,Cauet S,Pailles Y,Bettgenhaeuser J,Gapa L,Scarcelli N,Couderc M,Zekraoui L,Kathiresan N,Čížková J,Hřibová E,Doležel J,Arribat S,Bergès H,Wieringa JJ,Gueye M,Kane NA,Leclerc C

更新日期：2020-09-08 00:00:00

abstract：:Most DNA in the genomes of higher organisms does not encode proteins, yet much is transcribed by RNA polymerase II (RNAPII) into long non-coding RNAs (lncRNAs). The biological significance of most lncRNAs is largely unclear. Here, we identify a lncRNA (SVALKA) in a cold-sensitive region of the Arabidopsis genome. Muta...

journal_title：Nature communications

authors： Kindgren P,Ard R,Ivanov M,Marquardt S

更新日期：2018-11-01 00:00:00

abstract：:Plant phytochromes are thought to transduce light signals by mediating the degradation of phytochrome-interacting transcription factors (PIFs) through the N-terminal photosensory module, while the C-terminal module, including a histidine kinase-related domain (HKRD), does not participate in signaling. Here we show tha...

journal_title：Nature communications

authors： Qiu Y,Pasoreck EK,Reddy AK,Nagatani A,Ma W,Chory J,Chen M

更新日期：2017-12-04 00:00:00

abstract：:The mixed layer of modern oceans is a zone of fully homogenized sediment resulting from bioturbation. The mixed layer is host to complex biogeochemical cycles that directly impact ecosystem functioning, affecting ocean productivity and marine biodiversity. The timing of origin of the mixed layer has been controversial...

journal_title：Nature communications

authors： Gougeon RC,Mángano MG,Buatois LA,Narbonne GM,Laing BA

更新日期：2018-05-15 00:00:00

abstract：:Pulsars are rotating neutron stars emitting lighthouse-like beams. Owing to their unique properties, pulsars are a unique astrophysical tool to test general relativity, inform on matter in extreme conditions, and probe galactic magnetic fields. Understanding pulsar physics and emission mechanisms is critical to these ...

journal_title：Nature communications

authors： Gueroult R,Shi Y,Rax JM,Fisch NJ

更新日期：2019-07-19 00:00:00

abstract：:Anthropogenic CO2 emissions are causing ocean acidification, which can affect the physiology of marine organisms. Here we assess the possible effects of ocean acidification on the metabolic potential of sponge symbionts, inferred by metagenomic analyses of the microbiomes of two sponge species sampled at a shallow vol...

journal_title：Nature communications

authors： Botté ES,Nielsen S,Abdul Wahab MA,Webster J,Robbins S,Thomas T,Webster NS

更新日期：2019-09-12 00:00:00

abstract：:The basal ganglia, and the striatum in particular, have been implicated in the generation of contraversive movements. The striatum projects to downstream basal ganglia nuclei through two main circuits, originating in striatonigral and striatopallidal neurons, and different models postulate that the two pathways can wo...

journal_title：Nature communications

authors： Tecuapetla F,Matias S,Dugue GP,Mainen ZF,Costa RM

更新日期：2014-07-08 00:00:00

abstract：:Regulatory T (Treg) cells derived from the thymus (tTreg) and periphery (pTreg) have central and distinct functions in immunosuppression, but mechanisms for the generation and activation of Treg subsets in vivo are unclear. Here, we show that mechanistic target of rapamycin (mTOR) unexpectedly supports the homeostasis...

journal_title：Nature communications

authors： Chapman NM,Zeng H,Nguyen TM,Wang Y,Vogel P,Dhungana Y,Liu X,Neale G,Locasale JW,Chi H

更新日期：2018-05-29 00:00:00

abstract：:Compartmentalization of the gut microbiota is thought to be important to system function, but the extent of spatial organization in the gut ecosystem remains poorly understood. Here, we profile the murine colonic microbiota along longitudinal and lateral axes using laser capture microdissection. We found fine-scale sp...

journal_title：Nature communications

authors： Riva A,Kuzyk O,Forsberg E,Siuzdak G,Pfann C,Herbold C,Daims H,Loy A,Warth B,Berry D

更新日期：2019-09-25 00:00:00

abstract：:Since the 1970s, it has been known that black-hole (and other) horizons are truly thermodynamic. More generally, surfaces which are not horizons have also been conjectured to behave thermodynamically. Initially, for surfaces microscopically expanded from a horizon to so-called stretched horizons, and more recently, fo...

journal_title：Nature communications

authors： Wang ZW,Braunstein SL

更新日期：2018-07-30 00:00:00

abstract：:Previous studies have revealed that nucleosomes impede elongation of RNA polymerase II (RNAPII). Recent observations suggest a role for ATP-dependent chromatin remodellers in modulating this process, but direct in vivo evidence for this is unknown. Here using fission yeast, we identify Fun30Fft3 as a chromatin remodel...

journal_title：Nature communications

authors： Lee J,Choi ES,Seo HD,Kang K,Gilmore JM,Florens L,Washburn MP,Choe J,Workman JL,Lee D

更新日期：2017-02-20 00:00:00

abstract：:Mycobacterium tuberculosis is a pathogen with a unique cell envelope including very long fatty acids, implicated in bacterial resistance and host immune modulation. FasR is a TetR-like transcriptional activator that plays a central role in sensing mycobacterial long-chain fatty acids and regulating lipid biosynthesis....

journal_title：Nature communications

authors： Lara J,Diacovich L,Trajtenberg F,Larrieux N,Malchiodi EL,Fernández MM,Gago G,Gramajo H,Buschiazzo A

更新日期：2020-07-24 00:00:00

abstract：:The Barbier reaction, a widely utilized reaction for carbon-carbon bond formation, has played important roles in modern organic chemistry for more than a century. Here, we show its successful introduction to polymer chemistry. Through one-pot Barbier polyaddition (both A2+B2 type and AB type) of monomers containing an...

journal_title：Nature communications

authors： Sun XL,Liu DM,Tian D,Zhang XY,Wu W,Wan WM

更新日期：2017-10-31 00:00:00

abstract：:The original version of the Supplementary Information associated with this Article contained errors in Supplementary Figures 2, 12, 20 and 22. The HTML has been updated to include a corrected version of the Supplementary Information; the original incorrect versions of these Figures can be found as Supplementary Inform...

journal_title：Nature communications

authors： Eberlein C,Hénault M,Fijarczyk A,Charron G,Bouvier M,Kohn LM,Anderson JB,Landry CR

更新日期：2019-05-13 00:00:00

abstract：:We study spin transport in a fully hBN encapsulated monolayer-graphene van der Waals heterostructure at room temperature. A top-layer of bilayer-hBN is used as a tunnel barrier for spin-injection and detection in graphene with ferromagnetic cobalt electrodes. We report surprisingly large and bias-induced (differential...

journal_title：Nature communications

authors： Gurram M,Omar S,Wees BJV

更新日期：2017-08-15 00:00:00

abstract：:Genetic screens are powerful tools to identify the genes required for a given biological process. However, for technical reasons, comprehensive screens have been restricted to very few model organisms. Therefore, although deep sequencing is revealing the genes of ever more insect species, the functional studies predom...

journal_title：Nature communications

authors： Schmitt-Engel C,Schultheis D,Schwirz J,Ströhlein N,Troelenberg N,Majumdar U,Dao VA,Grossmann D,Richter T,Tech M,Dönitz J,Gerischer L,Theis M,Schild I,Trauner J,Koniszewski ND,Küster E,Kittelmann S,Hu Y,Lehmann S,S

更新日期：2015-07-28 00:00:00

abstract：:Microbial population growth is typically measured when cells can be directly observed, or when death is rare. However, neither of these conditions hold for the mammalian gut microbiota, and, therefore, standard approaches cannot accurately measure the growth dynamics of this community. Here we introduce a new method (...

journal_title：Nature communications

authors： Myhrvold C,Kotula JW,Hicks WM,Conway NJ,Silver PA

更新日期：2015-11-30 00:00:00

abstract：:Rotational invariance strongly constrains the viscosity tensor of classical fluids. When this symmetry is broken in anisotropic materials a wide array of novel phenomena become possible. We explore electron fluid behaviors arising from the most general viscosity tensors in two and three dimensions, constrained only th...

journal_title：Nature communications

authors： Varnavides G,Jermyn AS,Anikeeva P,Felser C,Narang P

更新日期：2020-09-18 00:00:00

abstract：:Impaired function in the medial prefrontal cortex (mPFC) contributes to depression, and the therapeutic response produced by novel rapid-acting antidepressants such as ketamine are mediated by mPFC activity. The mPFC contains multiple types of pyramidal cells, but it is unclear whether a particular subtype mediates th...

journal_title：Nature communications

authors： Hare BD,Shinohara R,Liu RJ,Pothula S,DiLeone RJ,Duman RS

更新日期：2019-01-15 00:00:00

abstract：:FDA proactively invests in tools to support innovation of emerging technologies, such as infectious disease next generation sequencing (ID-NGS). Here, we introduce FDA-ARGOS quality-controlled reference genomes as a public database for diagnostic purposes and demonstrate its utility on the example of two use cases. We...

journal_title：Nature communications

authors： Sichtig H,Minogue T,Yan Y,Stefan C,Hall A,Tallon L,Sadzewicz L,Nadendla S,Klimke W,Hatcher E,Shumway M,Aldea DL,Allen J,Koehler J,Slezak T,Lovell S,Schoepp R,Scherf U

更新日期：2019-07-25 00:00:00

abstract：:Thanks to the nature of strong programmability, field-programmable gate arrays (FPGAs) have been playing a significant role in signal processing and control. With the explosive growth in digital data, big data analytics becomes an important emerging field, in which FPGAs are a major player. However, the computational ...

journal_title：Nature communications

authors： Zhang W,Yao J

更新日期：2020-01-21 00:00:00

abstract：:Single-cell RNA-sequencing (scRNA-Seq) is a compelling approach to directly and simultaneously measure cellular composition and state, which can otherwise only be estimated by applying deconvolution methods to bulk RNA-Seq estimates. However, it has not yet become a widely used tool in population-scale analyses, due t...

journal_title：Nature communications

authors： Mandric I,Schwarz T,Majumdar A,Hou K,Briscoe L,Perez R,Subramaniam M,Hafemeister C,Satija R,Ye CJ,Pasaniuc B,Halperin E

更新日期：2020-10-30 00:00:00

abstract：:Twisted Laguerre-Gaussian lasers, with orbital angular momentum and characterized by doughnut-shaped intensity profiles, provide a transformative set of tools and research directions in a growing range of fields and applications, from super-resolution microcopy and ultra-fast optical communications to quantum computin...

journal_title：Nature communications

authors： Vieira J,Trines RM,Alves EP,Fonseca RA,Mendonça JT,Bingham R,Norreys P,Silva LO

更新日期：2016-01-28 00:00:00

abstract：:Cytidine base editors (CBEs) and adenine base editors (ABEs), composed of a cytidine deaminase or an evolved adenine deaminase fused to Cas9 nickase, enable the conversion of C·G to T·A or A·T to G·C base pair in organisms, respectively. Here, we show that BE3 and ABE7.10 systems can achieve a targeted mutation effici...

journal_title：Nature communications

authors： Liu Z,Chen M,Chen S,Deng J,Song Y,Lai L,Li Z

更新日期：2018-07-13 00:00:00

abstract：:Our memories enable us to form expectations for our future experiences, yet the precise neural mechanisms underlying how we compare any experience to our memory remain unknown. Here, using intracranial EEG recordings, we show that episodic memories formed after a single visual experience establish expectations for fut...

journal_title：Nature communications

authors： Haque RU,Inati SK,Levey AI,Zaghloul KA

更新日期：2020-11-27 00:00:00

abstract：:The xeroderma pigmentosum C (XPC) complex initiates nucleotide excision repair by recognizing DNA lesions before recruiting downstream factors. How XPC detects structurally diverse lesions embedded within normal DNA is unknown. Here we present a crystal structure that captures the yeast XPC orthologue (Rad4) on a sing...

journal_title：Nature communications

authors： Chen X,Velmurugu Y,Zheng G,Park B,Shim Y,Kim Y,Liu L,Van Houten B,He C,Ansari A,Min JH

更新日期：2015-01-06 00:00:00

abstract：:Forests impact regional hydrology and climate directly by regulating water and heat fluxes. Indirect effects through cloud formation and precipitation can be important in facilitating continental-scale moisture recycling but are poorly understood at regional scales. In particular, the impact of temperate forest on clo...

journal_title：Nature communications

authors： Teuling AJ,Taylor CM,Meirink JF,Melsen LA,Miralles DG,van Heerwaarden CC,Vautard R,Stegehuis AI,Nabuurs GJ,de Arellano JV

更新日期：2017-01-11 00:00:00