The introduction of the Barbier reaction into polymer chemistry.

abstract：:Multiphoton absorption processes enable many technologically important applications, such as in vivo imaging, photodynamic therapy and optical limiting, and so on. Specifically, higher-order nonlinear absorption such as five-photon absorption offers significant advantages of greater spatial confinement, increased pene...

journal_title：Nature communications

authors： Chen W,Bhaumik S,Veldhuis SA,Xing G,Xu Q,Grätzel M,Mhaisalkar S,Mathews N,Sum TC

更新日期：2017-05-12 00:00:00

abstract：:Ubiquitin-specific protease 14 (USP14) is one of the major proteasome-associated deubiquitinating enzymes critical for proteome homeostasis. However, substrates of USP14 remain largely unknown, hindering the understanding of its functional roles. Here we conduct a comprehensive proteome, ubiquitinome and interactome a...

journal_title：Nature communications

authors： Liu B,Jiang S,Li M,Xiong X,Zhu M,Li D,Zhao L,Qian L,Zhai L,Li J,Lu H,Sun S,Lin J,Lu Y,Li X,Tan M

更新日期：2018-11-13 00:00:00

abstract：:Autophagy-mediated degradation of mitochondria (mitophagy) is a key process in cellular quality control. Although mitophagy impairment is involved in several patho-physiological conditions, valuable methods to induce mitophagy with low toxicity in vivo are still lacking. Herein, we describe a new optogenetic tool to s...

journal_title：Nature communications

authors： D'Acunzo P,Strappazzon F,Caruana I,Meneghetti G,Di Rita A,Simula L,Weber G,Del Bufalo F,Dalla Valle L,Campello S,Locatelli F,Cecconi F

更新日期：2019-04-04 00:00:00

abstract：:Wntless transports Wnt morphogens to the cell surface and is required for Wnt secretion and morphogenic gradients formation. Recycling of endocytosed Wntless requires the sorting nexin-3 (SNX3)-retromer-dependent endosome-to-Golgi transport pathway. Here we demonstrate the essential role of SNX3-retromer assembly for ...

journal_title：Nature communications

authors： McGough IJ,de Groot REA,Jellett AP,Betist MC,Varandas KC,Danson CM,Heesom KJ,Korswagen HC,Cullen PJ

更新日期：2018-09-13 00:00:00

abstract：:With favourable error thresholds and requiring only nearest-neighbour interactions on a lattice, the surface code is an error-correcting code that has garnered considerable attention. At the heart of this code is the ability to perform a low-weight parity measurement of local code qubits. Here we demonstrate high-fide...

journal_title：Nature communications

authors： Chow JM,Gambetta JM,Magesan E,Abraham DW,Cross AW,Johnson BR,Masluk NA,Ryan CA,Smolin JA,Srinivasan SJ,Steffen M

更新日期：2014-06-24 00:00:00

abstract：:Despite their energy-efficient merits as promising light-weight structural materials, magnesium (Mg) based alloys suffer from inadequate corrosion resistance. One primary reason is that the native surface film on Mg formed in air mainly consists of Mg(OH)2 and MgO, which is porous and unprotective, especially in humid...

journal_title：Nature communications

authors： Wang Y,Liu B,Zhao X,Zhang X,Miao Y,Yang N,Yang B,Zhang L,Kuang W,Li J,Ma E,Shan Z

更新日期：2018-10-03 00:00:00

abstract：:The principles governing the recruitment of interneurons during acceleration in vertebrate locomotion are unknown. In the mouse, the V2a spinal interneurons are dispensable for left-right coordination at low locomotor frequencies, but their function is essential for maintaining left-right coordination at high frequenc...

journal_title：Nature communications

authors： Zhong G,Sharma K,Harris-Warrick RM

更新日期：2011-01-01 00:00:00

abstract：:Untethered small actuators have various applications in multiple fields. However, existing small-scale actuators are very limited in their intractability with their surroundings, respond to only a single type of stimulus and are unable to achieve programmable structural changes under different stimuli. Here, we presen...

journal_title：Nature communications

authors： Dong Y,Wang J,Guo X,Yang S,Ozen MO,Chen P,Liu X,Du W,Xiao F,Demirci U,Liu BF

更新日期：2019-09-09 00:00:00

abstract：:Axially chiral compounds play an important role in areas such as asymmetric catalysis. The tyrosine click-like reaction is an efficient approach for synthesis of urazoles with potential applications in pharmaceutical and asymmetric catalysis. Here we discover a class of urazole with axial chirality by restricted rotat...

journal_title：Nature communications

authors： Zhang JW,Xu JH,Cheng DJ,Shi C,Liu XY,Tan B

更新日期：2016-02-11 00:00:00

abstract：:Graphene and hexagonal boron nitride are typical conductor and insulator, respectively, while their hybrids hexagonal boron carbonitride are promising as a semiconductor. Here we demonstrate a direct chemical conversion reaction, which systematically converts the hexagonal carbon lattice of graphene to boron nitride, ...

journal_title：Nature communications

authors： Gong Y,Shi G,Zhang Z,Zhou W,Jung J,Gao W,Ma L,Yang Y,Yang S,You G,Vajtai R,Xu Q,MacDonald AH,Yakobson BI,Lou J,Liu Z,Ajayan PM

更新日期：2014-01-01 00:00:00

abstract：:Hyperconnected network architectures can endow nanomaterials with remarkable mechanical properties that are fundamentally controlled by designing connectivity into the intrinsic molecular structure. For hybrid organic-inorganic nanomaterials, here we show that by using 1,3,5 silyl benzene precursors, the connectivity ...

journal_title：Nature communications

authors： Burg JA,Oliver MS,Frot TJ,Sherwood M,Lee V,Dubois G,Dauskardt RH

更新日期：2017-10-18 00:00:00

abstract：:Textiles that are capable of harvesting biomechanical energy via triboelectric effects are of interest for self-powered wearable electronics. Fabrication of conformable and durable textiles with high triboelectric outputs remains challenging. Here we propose a washable skin-touch-actuated textile-based triboelectric n...

journal_title：Nature communications

authors： Xiong J,Cui P,Chen X,Wang J,Parida K,Lin MF,Lee PS

更新日期：2018-10-15 00:00:00

abstract：:We report color-selective photodetection from intermediate, monolayered, quantum dots buried in between amorphous-oxide semiconductors. The proposed active channel in phototransistors is a hybrid configuration of oxide-quantum dot-oxide layers, where the gate-tunable electrical property of silicon-doped, indium-zinc-o...

journal_title：Nature communications

authors： Cho KS,Heo K,Baik CW,Choi JY,Jeong H,Hwang S,Lee SY

更新日期：2017-10-10 00:00:00

abstract：:Natural killer (NK) cells are cytotoxic innate lymphoid cells that are involved in immune defense. NK cell reactivity is controlled in part by MHC class I recognition by inhibitory receptors, but the underlying molecular mechanisms remain undefined. Using a mouse model of conditional deletion in NK cells, we show here...

journal_title：Nature communications

authors： Viant C,Fenis A,Chicanne G,Payrastre B,Ugolini S,Vivier E

更新日期：2014-10-30 00:00:00

abstract：:Netrins, a family of laminin-related molecules, have been proposed to act as guidance cues either during nervous system development or the establishment of the vascular system. This was clearly demonstrated for netrin-1 via its interaction with the receptors DCC and UNC5s. However, mainly based on shared homologies wi...

journal_title：Nature communications

authors： Reuten R,Patel TR,McDougall M,Rama N,Nikodemus D,Gibert B,Delcros JG,Prein C,Meier M,Metzger S,Zhou Z,Kaltenberg J,McKee KK,Bald T,Tüting T,Zigrino P,Djonov V,Bloch W,Clausen-Schaumann H,Poschl E,Yurchenco PD,Eh

更新日期：2016-11-30 00:00:00

abstract：:Hypertensive disorders in pregnancy (HDPs) are leading perinatal diseases. Using a national cohort of 2,043,182 pregnant women in China, we evaluated the association between ambient temperatures and HDP subgroups, including preeclampsia or eclampsia, gestational hypertension, and superimposed preeclampsia. Under extre...

journal_title：Nature communications

authors： Xiong T,Chen P,Mu Y,Li X,Di B,Li J,Qu Y,Tang J,Liang J,Mu D

更新日期：2020-06-10 00:00:00

abstract：:Engineering catalytic sites at the atomic level provides an opportunity to understand the catalyst's active sites, which is vital to the development of improved catalysts. Here we show a reliable and tunable polyoxometalate template-based synthetic strategy to atomically engineer metal doping sites onto metallic 1T-Mo...

journal_title：Nature communications

authors： Huang Y,Sun Y,Zheng X,Aoki T,Pattengale B,Huang J,He X,Bian W,Younan S,Williams N,Hu J,Ge J,Pu N,Yan X,Pan X,Zhang L,Wei Y,Gu J

更新日期：2019-02-28 00:00:00

abstract：:Phonons are the main source of relaxation in molecular nanomagnets, and different mechanisms have been proposed in order to explain the wealth of experimental findings. However, very limited experimental investigations on phonons in these systems have been performed so far, yielding no information about their dispersi...

journal_title：Nature communications

authors： Garlatti E,Tesi L,Lunghi A,Atzori M,Voneshen DJ,Santini P,Sanvito S,Guidi T,Sessoli R,Carretta S

更新日期：2020-04-09 00:00:00

abstract：:Exocytic transmitter release is regulated by the SNARE complex, which contains a vesicular protein, synaptobrevin2 (Sb2). However, Sb2 vesicular arrangement is unclear. Here we use super-resolution fluorescence microscopy to study the prevalence and distribution of endogenous and exogenous Sb2 in single vesicles of as...

journal_title：Nature communications

authors： Singh P,Jorgačevski J,Kreft M,Grubišić V,Stout RF Jr,Potokar M,Parpura V,Zorec R

更新日期：2014-05-07 00:00:00

abstract：:The genome of the thermophilic bacterium, Aeribacillus pallidus 8, encodes the bacteriocin pallidocin. It belongs to the small class of glycocins and is posttranslationally modified, containing an S-linked glucose on a specific Cys residue. In this study, the pallidocin biosynthetic machinery is cloned and expressed i...

journal_title：Nature communications

authors： Kaunietis A,Buivydas A,Čitavičius DJ,Kuipers OP

更新日期：2019-03-07 00:00:00

abstract：:Metallic nanostructures exhibit a multitude of optical resonances associated with localized surface plasmon excitations. Recent observations of plasmonic phenomena at the sub-nanometre to atomic scale have stimulated the development of various sophisticated theoretical approaches for their description. Here instead we...

journal_title：Nature communications

authors： Mortensen NA,Raza S,Wubs M,Søndergaard T,Bozhevolnyi SI

更新日期：2014-05-02 00:00:00

abstract：:Radiotherapy is not currently informed by the genetic composition of an individual patient's tumour. To identify genetic features regulating survival after DNA damage, here we conduct large-scale profiling of cellular survival after exposure to radiation in a diverse collection of 533 genetically annotated human tumou...

journal_title：Nature communications

authors： Yard BD,Adams DJ,Chie EK,Tamayo P,Battaglia JS,Gopal P,Rogacki K,Pearson BE,Phillips J,Raymond DP,Pennell NA,Almeida F,Cheah JH,Clemons PA,Shamji A,Peacock CD,Schreiber SL,Hammerman PS,Abazeed ME

更新日期：2016-04-25 00:00:00

abstract：:The fracture toughness of glassy materials remains poorly understood. In large part, this is due to the disordered, intrinsically non-equilibrium nature of the glass structure, which challenges its theoretical description and experimental determination. We show that the notch fracture toughness of metallic glasses exh...

journal_title：Nature communications

authors： Ketkaew J,Chen W,Wang H,Datye A,Fan M,Pereira G,Schwarz UD,Liu Z,Yamada R,Dmowski W,Shattuck MD,O'Hern CS,Egami T,Bouchbinder E,Schroers J

更新日期：2018-08-16 00:00:00

abstract：:Coupling vibrational transitions to resonant optical modes creates vibrational polaritons shifted from the uncoupled molecular resonances and provides a convenient way to modify the energetics of molecular vibrations. This approach is a viable method to explore controlling chemical reactivity. In this work, we report ...

journal_title：Nature communications

authors： Dunkelberger AD,Spann BT,Fears KP,Simpkins BS,Owrutsky JC

更新日期：2016-11-22 00:00:00

abstract：:Acoustic waves, capable of transmitting through optically opaque objects, have been widely used in biomedical imaging, industrial sensing and particle manipulation. High-fidelity wave front shaping is essential to further improve performance in these applications. An acoustic analog to the successful spatial light mod...

journal_title：Nature communications

authors： Ma Z,Melde K,Athanassiadis AG,Schau M,Richter H,Qiu T,Fischer P

更新日期：2020-09-10 00:00:00

abstract：:Circuit reactivations involve a stereotyped sequence of neuronal firing and have been behaviourally linked to memory consolidation. Here we use multiphoton imaging and patch-clamp recording, and observe sparse and stereotyped circuit reactivations that correspond to UP states within active neurons. To evaluate the eff...

journal_title：Nature communications

authors： Kruskal PB,Li L,MacLean JN

更新日期：2013-01-01 00:00:00

abstract：:Autoimmunity and macrophage recruitment into the central nervous system (CNS) are critical determinants of neuroinflammatory diseases. However, the mechanisms that drive immunological responses targeted to the CNS remain largely unknown. Here we show that fibrinogen, a central blood coagulation protein deposited in th...

journal_title：Nature communications

authors： Ryu JK,Petersen MA,Murray SG,Baeten KM,Meyer-Franke A,Chan JP,Vagena E,Bedard C,Machado MR,Rios Coronado PE,Prod'homme T,Charo IF,Lassmann H,Degen JL,Zamvil SS,Akassoglou K

更新日期：2015-09-10 00:00:00

abstract：:Hydrogen-Deuterium eXchange coupled to Mass Spectrometry (HDX-MS) is now common practice in structural biology. However, it is most of the time applied to rather small oligomeric complexes. Here, we report on the use of HDX-MS to investigate conformational differences between the human standard 20S (std20S) and immuno...

journal_title：Nature communications

authors： Lesne J,Locard-Paulet M,Parra J,Zivković D,Menneteau T,Bousquet MP,Burlet-Schiltz O,Marcoux J

更新日期：2020-12-01 00:00:00

abstract：:After stroke, peripheral immune cells are activated and these systemic responses may amplify brain damage, but how the injured brain sends out signals to trigger systemic inflammation remains unclear. Here we show that a brain-to-cervical lymph node (CLN) pathway is involved. In rats subjected to focal cerebral ischem...

journal_title：Nature communications

authors： Esposito E,Ahn BJ,Shi J,Nakamura Y,Park JH,Mandeville ET,Yu Z,Chan SJ,Desai R,Hayakawa A,Ji X,Lo EH,Hayakawa K

更新日期：2019-11-22 00:00:00

abstract：:Many decisions are based on an internal model of the world. Yet, how such a model is constructed from experience and represented in memory remains unknown. We test the hypothesis that reward shapes memory for sequences of events by retroactively prioritizing memory for objects as a function of their distance from rewa...

journal_title：Nature communications

authors： Braun EK,Wimmer GE,Shohamy D

更新日期：2018-11-20 00:00:00