Abstract:
:Twisted Laguerre-Gaussian lasers, with orbital angular momentum and characterized by doughnut-shaped intensity profiles, provide a transformative set of tools and research directions in a growing range of fields and applications, from super-resolution microcopy and ultra-fast optical communications to quantum computing and astrophysics. The impact of twisted light is widening as recent numerical calculations provided solutions to long-standing challenges in plasma-based acceleration by allowing for high-gradient positron acceleration. The production of ultra-high-intensity twisted laser pulses could then also have a broad influence on relativistic laser-matter interactions. Here we show theoretically and with ab initio three-dimensional particle-in-cell simulations that stimulated Raman backscattering can generate and amplify twisted lasers to petawatt intensities in plasmas. This work may open new research directions in nonlinear optics and high-energy-density science, compact plasma-based accelerators and light sources.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Vieira J,Trines RM,Alves EP,Fonseca RA,Mendonça JT,Bingham R,Norreys P,Silva LOdoi
10.1038/ncomms10371subject
Has Abstractpub_date
2016-01-28 00:00:00pages
10371issn
2041-1723pii
ncomms10371journal_volume
7pub_type
杂志文章abstract::Transcriptome-wide association studies integrate gene expression data with common risk variation to identify gene-trait associations. By incorporating epigenome data to estimate the functional importance of genetic variation on gene expression, we generate a small but significant improvement in the accuracy of transcr...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-11874-7
更新日期:2019-08-23 00:00:00
abstract::Understanding the formation chemistry of metal halide perovskites is key to optimizing processing conditions and realizing enhanced optoelectronic properties. Here, we reveal the structure of the crystalline precursor in the formation of methylammonium lead iodide (MAPbI3) from the single-step deposition of lead chlor...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-05937-4
更新日期:2018-08-27 00:00:00
abstract::Alterations in the methylation of promoters of cancer-related genes are promising biomarkers for the early detection of disease. Compared with single methylation alteration, assessing combined methylation alterations can provide higher association with specific cancer. Here we use cationic conjugated polymer-based flu...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms2209
更新日期:2012-01-01 00:00:00
abstract::Metal-organic frameworks (MOFs) are well known for their tunable structure and porosity. Many studies have shown they are promising for various important applications, for which their performance can be further enhanced by encapsulating functional species, such as luminescent guest molecules, within the frameworks. Al...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3717
更新日期:2013-01-01 00:00:00
abstract::While main group elements have four valence orbitals accessible for bonding, quadruple bonding to main group elements is extremely rare. Here we report that main group element boron is able to form quadruple bonding interactions with iron in the BFe(CO)3- anion complex, which has been revealed by quantum chemical inve...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-12767-5
更新日期:2019-10-17 00:00:00
abstract::Cell competition is an emerging principle that eliminates suboptimal or potentially dangerous cells. For 'unfit' cells to be detected, their competitive status needs to be compared to the collective fitness of cells within a tissue. Here we report that the NMDA receptor controls cell competition of epithelial cells an...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16070-6
更新日期:2020-05-06 00:00:00
abstract::Neural crest migration is critical to its physiological function. Mechanisms controlling mammalian neural crest migration are comparatively unknown, due to difficulties accessing this cell population in vivo. Here we report requirements of glycogen synthase kinase 3 (GSK3) in regulating the neural crest in Xenopus and...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03512-5
更新日期:2018-03-19 00:00:00
abstract::Heparin-like oligosaccharides mediate numerous important biological interactions, of which many are implicated in various diseases. Synthetic improvements are central to the development of such oligosaccharides as therapeutics and, in addition, there are no methods to elucidate the pharmacokinetics of structurally def...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3016
更新日期:2013-01-01 00:00:00
abstract::Capturing and controlling plasmons at buried interfaces with nanometre and femtosecond resolution has yet to be achieved and is critical for next generation plasmonic devices. Here we use light to excite plasmonic interference patterns at a buried metal-dielectric interface in a nanostructured thin film. Plasmons are ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms13156
更新日期:2016-10-11 00:00:00
abstract::Accumulating evidence suggests that transcriptional regulation is required for maintenance of long-term memories (LTMs). Here we characterize global transcriptional and epigenetic changes that occur during LTM storage in the Drosophila mushroom bodies (MBs), structures important for memory. Although LTM formation requ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms13471
更新日期:2016-11-14 00:00:00
abstract::5-Deoxyribose is formed from 5'-deoxyadenosine, a toxic byproduct of radical S-adenosylmethionine (SAM) enzymes. The degradative fate of 5-deoxyribose is unknown. Here, we define a salvage pathway for 5-deoxyribose in bacteria, consisting of phosphorylation, isomerization, and aldol cleavage steps. Analysis of bacteri...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-05589-4
更新日期:2018-08-06 00:00:00
abstract::Tumour-associated macrophages (TAMs) play an important role in tumour progression, which is facilitated by their ability to respond to environmental cues. Here we report, using murine models of breast cancer, that TAMs expressing fibroblast activation protein alpha (FAP) and haem oxygenase-1 (HO-1), which are also fou...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-05346-7
更新日期:2018-07-27 00:00:00
abstract::D-Glucosamine (GlcN) is a freely available and commonly used dietary supplement potentially promoting cartilage health in humans, which also acts as an inhibitor of glycolysis. Here we show that GlcN, independent of the hexosamine pathway, extends Caenorhabditis elegans life span by impairing glucose metabolism that a...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms4563
更新日期:2014-04-08 00:00:00
abstract::Discarding by fisheries is perceived as contrary to responsible harvesting. Legislation seeking to end the practice is being introduced in many jurisdictions. However, discarded fish are food for a range of scavenging species; so, ending discarding may have ecological consequences. Here we investigate the sensitivity ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms4893
更新日期:2014-05-13 00:00:00
abstract::Scalable quantum networking requires quantum systems with quantum processing capabilities. Solid state spin systems with reliable spin-optical interfaces are a leading hardware in this regard. However, available systems suffer from large electron-phonon interaction or fast spin dephasing. Here, we demonstrate that the...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09873-9
更新日期:2019-04-26 00:00:00
abstract::The original version of this Article contained an error in the spelling of the author Jianyun Yan, which was incorrectly given as Jiangyun Yan. This has now been corrected in both the PDF and HTML versions of the Article. ...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41467-017-02617-7
更新日期:2018-01-12 00:00:00
abstract::Closed timelike curves are striking predictions of general relativity allowing for time-travel. They are afflicted by notorious causality issues (e.g. grandfather's paradox). Quantum models where a qubit travels back in time solve these problems, at the cost of violating quantum theory's linearity-leading e.g. to univ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-08100-1
更新日期:2019-01-14 00:00:00
abstract::Organic semiconductors are usually polycyclic aromatic hydrocarbons and their analogs containing heteroatom substitution. Bioinspired materials chemistry of organic electronics promises new charge transport mechanism and specific molecular recognition with biomolecules. We discover organic semiconductors from deoxyrib...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-12248-9
更新日期:2019-09-16 00:00:00
abstract::Various melting-related phenomena (like surface melting, size dependence of melting temperature, melting of few nm-size particles and overheating at a very fast heating rate) are of great fundamental and applied interest, although the corresponding theory is still lacking. Here we develop an advanced phase-field theor...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1275
更新日期:2011-01-01 00:00:00
abstract::Intentional doping is the core of semiconductor technologies to tune electrical and optical properties of semiconductors for electronic devices, however, it has shown to be a grand challenge for halide perovskites. Here, we show that some metal ions, such as silver, strontium, cerium ions, which exist in the precursor...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-20110-6
更新日期:2021-01-04 00:00:00
abstract::Device performance and in particular device stability for blue perovskite light-emitting diodes (PeLEDs) remain considerable challenges for the whole community. In this manuscript, we conceive an approach by tuning the 'A-site' cation composition of perovskites to develop blue-emitters. We herein report a Rubidium-Ces...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09794-7
更新日期:2019-04-23 00:00:00
abstract::Activation of free fatty acid receptor 1 (GPR40) by synthetic partial and full agonists occur via distinct allosteric sites. A crystal structure of GPR40-TAK-875 complex revealed the allosteric site for the partial agonist. Here we report the 2.76-Å crystal structure of human GPR40 in complex with a synthetic full ago...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-01240-w
更新日期:2018-04-25 00:00:00
abstract::Numerous examples of biosynthetic gene clusters (BGCs), including for compounds of agricultural and medicinal importance, have now been discovered in plant genomes. However, little is known about how these complex traits are assembled and diversified. Here, we examine a large number of variants within and between spec...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19153-6
更新日期:2020-10-23 00:00:00
abstract::The human brain has the capacity to rapidly change state, and in epilepsy these state changes can be catastrophic, resulting in loss of consciousness, injury and even death. Theoretical interpretations considering the brain as a dynamical system suggest that prior to a seizure, recorded brain signals may exhibit criti...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-15908-3
更新日期:2020-05-01 00:00:00
abstract::Inorganic perovskites such as CsPbX3 (X=Cl, Br, I) have attracted attention due to their excellent thermal stability and high photoluminescence quantum efficiency. However, the electroluminescence quantum efficiency of their light-emitting diodes was <1%. We posited that this low efficiency was a result of high leakag...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms15640
更新日期:2017-06-07 00:00:00
abstract::Fluctuations in glacier motion are very common and are thought to be controlled by subglacial hydrology and till deformation. There are few instrumented studies that have monitored seasonal changes. We use the innovative Glacsweb subglacial in situ wireless probes, combined with dGPS and custom geophone data from an I...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09547-6
更新日期:2019-04-08 00:00:00
abstract::Enlarged vestibular aqueduct (EVA) is one of the most commonly identified inner ear malformations in hearing loss patients including Pendred syndrome. While biallelic mutations of the SLC26A4 gene, encoding pendrin, causes non-syndromic hearing loss with EVA or Pendred syndrome, a considerable number of patients appea...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-15198-9
更新日期:2020-03-12 00:00:00
abstract::In fragmented forests, tree diversity declines near edges but the ecological processes underlying this loss of diversity remain poorly understood. Theory predicts that top-down regulation of seedling recruitment by insect herbivores and fungal pathogens contributes to maintaining tree diversity in forests, but it is u...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-06997-2
更新日期:2018-10-30 00:00:00
abstract::Dynamic changes in histone modifications under various physiological cues play important roles in gene transcription and cancer. Identification of new histone marks critical for cancer development is of particular importance. Here we show that, in a glucose-dependent manner, E3 ubiquitin ligase NEDD4 ubiquitinates his...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms14799
更新日期:2017-03-16 00:00:00
abstract::Translation efficiency can be affected by mRNA stability and secondary structures, including G-quadruplex structures (G4s). The highly conserved DEAH-box helicase DHX36/RHAU resolves G4s on DNA and RNA in vitro, however a systems-wide analysis of DHX36 targets and function is lacking. We map globally DHX36 binding to ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-10432-5
更新日期:2019-06-03 00:00:00