Abstract:
:TORC1 is arguably the best-studied regulator of cellular growth in eukaryotes. However, its activity has not been assessed in vivo in developing multicellular organisms. Two studies in this issue of Developmental Cell (Kim et al., 2017; Romero-Pozuelo et al., 2017) surprisingly reveal a patchy, cell-cycle-controlled pattern of TORC1 activation in Drosophila imaginal discs.
journal_name
Dev Celljournal_title
Developmental cellauthors
Stocker Hdoi
10.1016/j.devcel.2017.08.007subject
Has Abstractpub_date
2017-08-21 00:00:00pages
311-313issue
4eissn
1534-5807issn
1878-1551pii
S1534-5807(17)30635-4journal_volume
42pub_type
评论,杂志文章abstract::Our vasculature plays diverse and critical roles in homeostasis and disease. In recent decades, the use of zebrafish has driven our understanding of vascular development into new areas, identifying new genes and mechanisms controlling vessel formation and allowing unprecedented observation of the cellular and molecula...
journal_title:Developmental cell
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abstract::High-molecular-weight hyaluronan, a major component of the extracellular matrix, is anti-oncogenic, whereas low-molecular-weight hyaluronan is pro-oncogenic, though the mechanisms underlying the size-dependent opposite bioactivities of hyaluronan remain uncertain. We show here that treatment with high-molecular-weight...
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journal_title:Developmental cell
pub_type: 评论,杂志文章
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journal_title:Developmental cell
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journal_title:Developmental cell
pub_type: 评论,杂志文章
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journal_title:Developmental cell
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journal_title:Developmental cell
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journal_title:Developmental cell
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journal_title:Developmental cell
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journal_title:Developmental cell
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journal_title:Developmental cell
pub_type: 杂志文章
doi:10.1016/j.devcel.2020.09.021
更新日期:2020-12-07 00:00:00
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journal_title:Developmental cell
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journal_title:Developmental cell
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journal_title:Developmental cell
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journal_title:Developmental cell
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journal_title:Developmental cell
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