Antibacterial activity of the nitrovinylfuran G1 (Furvina) and its conversion products.

abstract：:Crystalline atomic layers on solid surfaces are composed of a single building block, unit cell, that is copied and stacked together to form the entire two-dimensional crystal structure. However, it appears that this is not an unique possibility. We report here on synthesis and characterization of the one-atomic-layer-...

journal_title：Scientific reports

authors： Gruznev DV,Bondarenko LV,Matetskiy AV,Mihalyuk AN,Tupchaya AY,Utas OA,Eremeev SV,Hsing CR,Chou JP,Wei CM,Zotov AV,Saranin AA

更新日期：2016-01-19 00:00:00

abstract：:Rapid diagnostic tests (RDTs) have been widely deployed in low-resource settings. These tests are typically read by visual inspection, and accurate record keeping and data aggregation remains a substantial challenge. A successful malaria elimination campaign will require new strategies that maximize the sensitivity of...

journal_title：Scientific reports

authors： Scherr TF,Gupta S,Wright DW,Haselton FR

更新日期：2016-06-27 00:00:00

abstract：:Parasites comprise a huge part of the biodiversity on earth. However, on a local scale, not much is known about their diversity and community structure. Here, we assess the diversity of larval trematode communities in an interconnected freshwater system of the River Ruhr in Germany and analyse how the parasites are sp...

journal_title：Scientific reports

authors： Selbach C,Soldánová M,Feld CK,Kostadinova A,Sures B

更新日期：2020-02-14 00:00:00

abstract：:The production of male and female offspring is often determined by the presence of specific sex chromosomes which control sex-specific expression, and sex chromosomes evolve through reduced recombination and specialized gene content. Here we present the genomes of Chrysomya rufifacies, a monogenic blow fly (females pr...

journal_title：Scientific reports

authors： Andere AA,Pimsler ML,Tarone AM,Picard CJ

更新日期：2020-09-25 00:00:00

abstract：:We show that the space in which scientific, technological and economic activities interplay with each other can be mathematically shaped using techniques from statistical physics of networks. We build a holistic view of the innovation system as the tri-layered network of interactions among these many activities (scien...

journal_title：Scientific reports

authors： Pugliese E,Cimini G,Patelli A,Zaccaria A,Pietronero L,Gabrielli A

更新日期：2019-11-11 00:00:00

abstract：:Incident myocardial infarction (MI) is a leading cause of adult mortality in the United States. However, because MI has a relatively low incidence in the young population, little information exists on the disease in younger adults. Because the retina has the unique quality that its vasculature is readily and noninvasi...

journal_title：Scientific reports

authors： Kromer R,Tigges E,Rashed N,Pein I,Klemm M,Blankenberg S

更新日期：2018-04-04 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Wang Z,Wang H,Tzvetanov T,Zhou Y

更新日期：2019-05-23 00:00:00

abstract：:The mammalian Target of Rapamycin complex 1 (mTORC1) nutrient-sensing pathway is a central regulator of cell growth and metabolism and is dysregulated in diabetes. The eukaryotic translation initiation factor 4E (EIF-4E) protein, a key regulator of gene translation and protein function, is controlled by mTORC1 and EIF...

journal_title：Scientific reports

authors： Soliman GA,Schooling CM

更新日期：2020-09-25 00:00:00

abstract：:Small for gestational age (SGA) is an established risk factor for cerebral palsy (CP) in term infants. However, there is conflicting data on the association between SGA and CP in moderate to late preterm infants. The aim of the article was to explore the relationship between SGA and CP in the moderate to late preterm ...

journal_title：Scientific reports

authors： Zhao M,Dai H,Deng Y,Zhao L

更新日期：2016-12-13 00:00:00

abstract：:Panax ginseng (GS) and Veratrum nigrum (VN) are representative of incompatible pairs in "eighteen antagonistic medicaments" that have been recorded in the Chinese medicinal literature for over 2,000 years. However, evidence linking interference effects with combination use is scare. Based on the estrogen-like effect o...

journal_title：Scientific reports

authors： Xu Y,Ding J,An JN,Qu YK,Li X,Ma XP,Zhang YM,Dai GJ,Lin N

更新日期：2016-05-27 00:00:00

abstract：:When and where animals breed can shape the genetic structure and diversity of animal populations. The importance of drivers of genetic diversity is amplified in island populations that tend to have more delineated gene pools compared to continental populations. Studies of relatedness as a function of the spatial distr...

journal_title：Scientific reports

authors： Garrett LJH,Myatt JP,Sadler JP,Dawson DA,Hipperson H,Colbourne JK,Dickey RC,Weber SB,Reynolds SJ

更新日期：2020-11-26 00:00:00

abstract：:Inhibitors of cyclin-dependent kinases (ICKs) are key regulators of cyclin-dependent kinase activities and cell division. Herein, we identified eight ICKs in maize, which we named Zeama;ICKs (ZmICKs). Primary sequencing and phylogenetic analyses were used to divide the ZmICK family into two classes: group B and group ...

journal_title：Scientific reports

authors： Xiao Q,Zhang C,Li H,Wei B,Wang Y,Huang H,Li Y,Yu G,Liu H,Zhang J,Liu Y,Hu Y,Huang Y

更新日期：2017-03-06 00:00:00

abstract：:Awarding CO2 offset credits may incentivize seagrass restoration projects and help reverse greenhouse gas (GHG) emissions from global seagrass loss. However, no study has quantified net GHG removal from the atmosphere from a seagrass restoration project, which would require coupled Corg stock and GHG flux enhancement ...

journal_title：Scientific reports

authors： Oreska MPJ,McGlathery KJ,Aoki LR,Berger AC,Berg P,Mullins L

更新日期：2020-04-30 00:00:00

abstract：:Internal solitary waves (ISWs) in the NE South China Sea (SCS) are tidally generated at the Luzon Strait. Their propagation, evolution, and dissipation processes involve numerous issues still poorly understood. Here, a novel method of seismic oceanography capable of capturing oceanic finescale structures is used to st...

journal_title：Scientific reports

authors： Tang Q,Wang C,Wang D,Pawlowicz R

更新日期：2014-06-20 00:00:00

abstract：:Zebrafish spontaneously regenerate the retina after injury. Although the gene expression profile has been extensively studied in this species during regeneration, this does not reflect protein function. To further understand the regenerative process in the zebrafish, we compared the proteomic profile of the retina dur...

journal_title：Scientific reports

authors： Eastlake K,Heywood WE,Tracey-White D,Aquino E,Bliss E,Vasta GR,Mills K,Khaw PT,Moosajee M,Limb GA

更新日期：2017-03-16 00:00:00

abstract：:In the last years, great advances have been made in therapies based in cold atmospheric plasmas (CAP). CAP generate reactive oxygen and nitrogen species (RONS) which can be transferred to liquids. These CAP activated liquids display the same biological efficacy (i.e. on killing cancer cells) as CAP themselves, opening...

journal_title：Scientific reports

authors： Labay C,Hamouda I,Tampieri F,Ginebra MP,Canal C

更新日期：2019-11-06 00:00:00

abstract：:The aim is to analyse the clinical presentation, treatment and outcomes in patients with Paget's disease with invasive ductal carcinoma (PD-IDC), with special emphasis on the role of surgical treatment. Using data obtained by the Surveillance, Epidemiology, and End Results (SEER) program from 2010-2013, we investigate...

journal_title：Scientific reports

authors： Wu Q,Ding X,Li J,Sun S,Zhu S,Wu J,Liu Q,Yao F,Sun S

更新日期：2017-04-19 00:00:00

abstract：:Three main surveillance systems (laboratory-confirmed, influenza-like illness (ILI) and nationwide Notifiable Infectious Diseases Reporting Information System (NIDRIS)) have been used for influenza surveillance in China. However, it is unclear which surveillance system is more reliable in developing influenza early wa...

journal_title：Scientific reports

authors： Yang X,Liu D,Wei K,Liu X,Meng L,Yu D,Li H,Li B,He J,Hu W

更新日期：2018-02-12 00:00:00

abstract：:It has previously been shown that the consumption of probiotics may have beneficial effects not only on peripheral tissues but also on the central nervous system and behavior via the microbiota-gut-brain axis, raising the possibility that treatment with probiotics could be an effective therapeutic strategy for managin...

journal_title：Scientific reports

authors： Kobayashi Y,Sugahara H,Shimada K,Mitsuyama E,Kuhara T,Yasuoka A,Kondo T,Abe K,Xiao JZ

更新日期：2017-10-18 00:00:00

abstract：:We have developed an optimized protocol for plasma targeted mRNA sequencing in our previous study. Here, we performed plasma targeted mRNA sequencing for 40 colorectal adenoma patients and 39 colonoscopy-proven normal controls in order to find potential circulating mRNA markers for colorectal adenoma. Results showed t...

journal_title：Scientific reports

authors： Xue VW,Cheung MT,Chan PT,Luk LLY,Lee VH,Au TC,Yu AC,Cho WCS,Tsang HFA,Chan AK,Wong SCC

更新日期：2019-09-10 00:00:00

abstract：:Lactic acidosis is common in critical care; by contrast, a subtype called alcohol-associated lactic acidosis (AALA) is rarely encountered. The primary purpose of this study was to determine the prognosis of AALA in critically ill patients and the second aim was to determine whether the survival was associated to the p...

journal_title：Scientific reports

authors： Yang CC,Chan KS,Tseng KL,Weng SF

更新日期：2016-10-17 00:00:00

abstract：:The liver has a variety of functions for maintaining homeostasis, and hepatocytes play a major role. In contrast with the high regenerative capacity of mature hepatocytes (MHs) in vivo, they have not been successfully expanded ex vivo. Here we demonstrate that CD44-positive cells sorted from small hepatocyte (SH) colo...

journal_title：Scientific reports

authors： Ishii M,Kino J,Ichinohe N,Tanimizu N,Ninomiya T,Suzuki H,Mizuguchi T,Hirata K,Mitaka T

更新日期：2017-04-11 00:00:00

abstract：:Spinal cord injury (SCI) is frequently accompanied by a degree of spontaneous functional recovery. The underlying mechanisms through which such recovery is generated remain elusive. In this study, we observed a significant spontaneous motor function recovery 14 to 28 days after spinal cord transection (SCT) in rats. U...

journal_title：Scientific reports

authors： Liu W,Shang FF,Xu Y,Belegu V,Xia L,Zhao W,Liu R,Wang W,Liu J,Li CY,Wang TH

更新日期：2015-11-23 00:00:00

abstract：:Combined treatment with 5-aminolevulinic acid (5-ALA) and X-rays improves tumor suppression in vivo. This is because the accumulated protoporphyrin IX from 5-ALA enhances the generation of ROS by the X-ray irradiation. In the present study, a high-energy medical linear accelerator was used instead of a non-medical low...

journal_title：Scientific reports

authors： Takahashi J,Murakami M,Mori T,Iwahashi H

更新日期：2018-02-09 00:00:00

abstract：:Abscisic acid (ABA) is an ancient stress hormone and is detectable in a wide variety of organisms where it regulates innate immunity and inflammation. Previously, we showed that oral supplementation with ABA decreased parasitemia in a mouse model of malaria, decreased liver and spleen pathology and reduced parasite tr...

journal_title：Scientific reports

authors： Glennon EKK,Megawati D,Torrevillas BK,Ssewanyana I,Huang L,Aweeka F,Greenhouse B,Adams LG,Luckhart S

更新日期：2018-06-11 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related mortality globally. Because most patients are diagnosed at advanced stages of the disease, multi-targeted tyrosine kinase inhibitor sorafenib is the only available drug to show limited effectiveness. Novel and effective therapies are unmet me...

journal_title：Scientific reports

authors： Wang J,Sun P,Chen Y,Yao H,Wang S

更新日期：2018-07-19 00:00:00

abstract：:Magnetic resonance imaging provides a noninvasive method for in situ monitoring of electrochemical processes involved in charge/discharge cycling of batteries. Determining how the electrochemical processes become irreversible, ultimately resulting in degraded battery performance, will aid in developing new battery mat...

journal_title：Scientific reports

authors： Tang JA,Dugar S,Zhong G,Dalal NS,Zheng JP,Yang Y,Fu R

更新日期：2013-01-01 00:00:00

abstract：:Antibody humanization is a key step in the preclinical phase of the development of therapeutic antibodies, originally developed and tested in non-human models (most typically, in mouse). The standard technique of Complementarity-Determining Regions (CDR) grafting into human Framework Regions of germline sequences has ...

journal_title：Scientific reports

authors： Clavero-Álvarez A,Di Mambro T,Perez-Gaviro S,Magnani M,Bruscolini P

更新日期：2018-10-04 00:00:00

abstract：:The human transcription elongation factor DSIF is highly conserved throughout all kingdoms of life and plays multiple roles during transcription. DSIF is a heterodimer, consisting of Spt4 and Spt5 that interacts with RNA polymerase II (RNAP II). DSIF binds to the elongation complex and induces promoter-proximal pausin...

journal_title：Scientific reports

authors： Zuber PK,Hahn L,Reinl A,Schweimer K,Knauer SH,Gottesman ME,Rösch P,Wöhrl BM

更新日期：2018-08-03 00:00:00

abstract：:The role of soil organic carbon in global carbon cycles is receiving increasing attention both as a potentially large and uncertain source of CO2 emissions in response to predicted global temperature rises, and as a natural sink for carbon able to reduce atmospheric CO2. There is general agreement that the technical p...

journal_title：Scientific reports

authors： Zomer RJ,Bossio DA,Sommer R,Verchot LV

更新日期：2017-11-14 00:00:00